Overview
Background
Dr Zachary Hawula is a postdoctoral research fellow in the Lymphoma Research Lab at the Frazer Institute located within the Translational Research Institute in Brisbane. Having completed his Doctor of Philosophy at the University of Queensland in 2021 investigating genetic and chemical modulators of iron metabolism, haemochromatosis and anaemia. After Completing his PhD, Zach research interests changed to developing novel cell lines using CRISPR/Cas9 prime editing which mimic the rare inherited condition Wilson's Disease. A copper overolad disorder causes copper levels to build up in several organs, especially the liver, brain and eyes. Since begining his role in the Lymphoma Research Lab in 2022, Zachary is now focused on using cutting edge technologies such as single cell RNAseq (scRNAseq) to understand rare B cell lymphomas primarily focusing on Primary Central Nervous System Lymphoma (PCNSL) and Secondary CNS Lymphoma.
Availability
- Dr Zachary Hawula is:
- Available for supervision
Research interests
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Tumour Immunology
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Primary CNS Lymphoma
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DLBCL
Works
Search Professor Zachary Hawula’s works on UQ eSpace
2024
Conference Publication
Multiomics Analysis of Paired Diagnosis and Relapse DLBCL Biopsies Shows a Reduction in T Cell Infiltration and Function at Relapse
Swain, Fiona, Burgess, Melinda, Kempe, Sarah, Sabdia, Muhammed B., Henden, Andrea S., Wight, Joel, Hawkes, Eliza A., Mutsando, Howard, Talaulikar, Dipti, Merida de Long, Lilia, Birch, Simone, Wyche, Penelope, Hawula, Zachary, Chowdhury, Rakin, Gandhi, Maher K. and Keane, Colm (2024). Multiomics Analysis of Paired Diagnosis and Relapse DLBCL Biopsies Shows a Reduction in T Cell Infiltration and Function at Relapse. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-199352
2023
Conference Publication
Gene expression and spatial transcriptomic analysis of paired diagnosis and relapse DLBCL biopsies show a reduction in T cell infiltration and function at relapse
Swain, F., Burgess, M., Kempe, S., Sabdia, M., Wight, J., Hawkes, E., Mutsando, H., Talaulikar, D., Merida de Long, L., Hawula, Z., Birch, S., Wyche, P., Gandhi, M. K. and Keane, C. (2023). Gene expression and spatial transcriptomic analysis of paired diagnosis and relapse DLBCL biopsies show a reduction in T cell infiltration and function at relapse. 17th International Conference on Malignant Lymphoma, Lugano, Switzerland, 13 - 17 June 2023. Chichester, West Sussex United Kingdom: Wiley-Blackwell. doi: 10.1002/hon.3164_191
2021
Journal Article
The effect of the flavonol rutin on serum and liver iron content in a genetic mouse model of iron overload
Hawula, Zachary J., Secondes, Eriza S., Wallace, Daniel F., Rishi, Gautam and Subramaniam, V. Nathan (2021). The effect of the flavonol rutin on serum and liver iron content in a genetic mouse model of iron overload. Bioscience Reports, 41 (7) BSR20210720. doi: 10.1042/BSR20210720
Supervision
Availability
- Dr Zachary Hawula is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Investigating the mechanisms of immune evasion in relapsed/refractory DLBCL
Associate Advisor
Other advisors: Associate Professor Colm Keane
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Doctor Philosophy
Immuno-genetic biomarkers of response in a prospective study of immune checkpoint therapy in primary CNS lymphoma
Associate Advisor
Other advisors: Associate Professor Arutha Kulasinghe, Associate Professor Colm Keane
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Doctor Philosophy
Investigation of responses to CAR-T cell therapy in PCNSL
Associate Advisor
Other advisors: Associate Professor Colm Keane
Media
Enquiries
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