Carlie Cullen

Dr Carlie Cullen leads the Glial Neurobiology, Cognition and Behaviour Research Group at Mater Research and is an Honorary Senior Research Fellow at the Menzies Institute for Medical Research, University of Tasmania. Her research vision is to understand the neurobiological mechanisms that drive healthy brain function, and what happens when the system goes awry, to inform the development of sustained and effective treatments for neurodevelopmental, neurological, and neuropsychiatric disorders. More specifically, Carlie and her team are working to demonstrate the importance of myelin formation during brain development and ongoing adaptability of myelin content in shaping the way information is processed in the brain, and subsequently how this impacts behavioural actions throughout life. By uncovering how myelination and myelin plasticity influences brain function and behaviour, Carlie hopes to determine whether these processes could be targeted to treat the pathological symptoms of neurodevelopmental disorders, neuropsychiatric disease, and other neurological conditions.

Dr Cullen attained her PhD from The University of Queensland in 2014, under the supervision of Professor Karen Moritz, Associate Professor Nickolas Lavidis and Associate Professor Thomas Burne, where she used rodent models to demonstrate that chronic exposure to even a small amount of alcohol during gestation was associated with long-lasting anxiety-like behaviour in adult offspring. Carlie then joined the laboratory of Prof. Kaylene Young at the Menzies Institute for Medical Research, University of Tasmania where she developed a passion for understanding how glial cells influence healthy brain function, cognition and behaviour. In particular, her research focussed on understanding how cells of the oligodendrocyte lineage communicate with neurons; how this communication influences learning, memory and motor behaviour and whether this interaction could be targeted to promote brain repair in diseases like multiple sclerosis (MS).