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Dr Pavlina Naydenova
Dr

Pavlina Naydenova

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Overview

Background

Dr Naydenova is an emerging early-career researcher in the field of quantum biotechnology with a rare cross-disciplinary expertise in quantum biotechnology and molecular biology. She specialises in single-molecule detection and optical trapping of proteins using biomolecular optomechanics approaches at the University of Queensland’s Quantum Optics Lab led by Prof. Warwick Bowen. She is interested in fundamental research questions such as the relationship between function-dynamics-structure in proteins, as well as applications of biomolecular optomechanics for sensing in sport (e.g. anti-doping) and in biosecurity contexts (e.g. plant pathogens).

Dr Naydenova holds a PhD in Pharmacognosy and Phytochemistry by the Medical University-Sofia, Bulgaria, where her research focused on plant biotechnology, epigenetics and plant-derived chiral metabolites with anti-cancer properties. Chiral metabolites have a property called chirality, also known as handedness, that underpins many interactions between molecules, including drugs binding to molecular targets such as proteins and enzymes to modulate activity. Her work was recognised with the Medical University – Sofia’s Award for best research in pharmacy, an annual distinction for outstanding doctoral and early-career researchers.

In 2023, she was awarded a prestigious National Intelligence Postdoctoral Research Grant to investigate protein dynamics using molecular optomechanics approaches. She joined Prof. Bowen's lab and successfully transitioned to the field of quantum biotechnology, securing over $1.2M in external research funding from Australian and Queensland Governments in the past two years. Previous experience in industry engagement and program management in Australia's higher education sector further provides a strong foundation for translating cutting-edge science into real-world applications, bridging academic innovation with practical impact.

In addition to her research development, Dr Naydenova is also committed to her leadership development. Through her affiliation with the Centre of Excellence in Quantum Biotechnology (QUBIC), she served as the inaugural co-Chair of the centre's EMCR Committee and is an active member of the centre's Outreach and Engagement Portfolio, engaging in STEM outreach to school students.

Dr Naydenova's goal is to harness and continue building skills and expertise to drive impactful cross-disciplinary research that can drive both applied and cutting-edge fundamental research in biosecurity and broader national security context.

Availability

Dr Pavlina Naydenova is:
Not available for supervision

Qualifications

  • Doctor of Philosophy of Pharmacy and Biology, Medical University of Sofia

Works

Search Professor Pavlina Naydenova’s works on UQ eSpace

14 works between 2010 and 2025

1 - 14 of 14 works

2025

Journal Article

Biomolecular condensates as emerging biomaterials: Functional mechanisms and advances in computational and experimental approaches

Zhu, Qiang, Raza, Zahra, Do-Ha, Dzung, De Costa, Emma, Sasheva, Pavlina, McAlary, Luke, Mahmodi, Hadi, Bowen, Warwick P., Ooi, Lezanne, Kabakova, Irina and Yu, Haibo (2025). Biomolecular condensates as emerging biomaterials: Functional mechanisms and advances in computational and experimental approaches. Advanced Materials, 37 (36) e10115, e10115. doi: 10.1002/adma.202510115

Biomolecular condensates as emerging biomaterials: Functional mechanisms and advances in computational and experimental approaches

2025

Journal Article

Correction to: Apoptotic mechanisms of the biotechnologically produced arylnaphtalene lignan justicidin B in the acute myeloid leukemia-derived cell line HL-60 (Pharmacological Reports, (2014), 66, 6, (1073-1076), 10.1016/j.pharep.2014.07.005)

Momekov, Georgi, Yossifov, Deyan, Guenova, Margarita, Michova, Albena, Stoyanov, Nikolay, Konstantinov, Spiro, Ionkov, Todor, Sasheva, Pavlina and Ionkova, Iliana (2025). Correction to: Apoptotic mechanisms of the biotechnologically produced arylnaphtalene lignan justicidin B in the acute myeloid leukemia-derived cell line HL-60 (Pharmacological Reports, (2014), 66, 6, (1073-1076), 10.1016/j.pharep.2014.07.005). Pharmacological Reports, 66 (6), 1073-1076. doi: 10.1007/s43440-025-00798-3

Correction to: Apoptotic mechanisms of the biotechnologically produced arylnaphtalene lignan justicidin B in the acute myeloid leukemia-derived cell line HL-60 (Pharmacological Reports, (2014), 66, 6, (1073-1076), 10.1016/j.pharep.2014.07.005)

2019

Journal Article

Modelling the interaction and prediction of mictrotubule assembly inhibition of podophyllotoxin and its derivatives by molecular docking

Atanasova, M. D., Sasheva, P., Yonkova, I. M. and Doytchinova, I. A. (2019). Modelling the interaction and prediction of mictrotubule assembly inhibition of podophyllotoxin and its derivatives by molecular docking. Bulgarian Chemical Communications, 51 (4), 513-520. doi: 10.34049/bcc.51.4.4987

Modelling the interaction and prediction of mictrotubule assembly inhibition of podophyllotoxin and its derivatives by molecular docking

2017

Book Chapter

Differentially methylated region-representational difference analysis (DMR-RDA): A powerful method to identify DMRs in uncharacterized genomes

Sasheva, Pavlina and Grossniklaus, Ueli (2017). Differentially methylated region-representational difference analysis (DMR-RDA): A powerful method to identify DMRs in uncharacterized genomes. Plant epigenetics methods and protocols. (pp. 113-125) edited by Igor Kovalchuk. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4899-7708-3_10

Differentially methylated region-representational difference analysis (DMR-RDA): A powerful method to identify DMRs in uncharacterized genomes

2017

Book Chapter

Small cells for big ideas: the cytotoxic podophyllotoxin and the long journey in discovering its biosynthetic pathway

Sasheva, Pavlina and Ionkova, Iliana (2017). Small cells for big ideas: the cytotoxic podophyllotoxin and the long journey in discovering its biosynthetic pathway. Biotechnology and production of anti-cancer compounds. (pp. 177-199) edited by Sonia Malik. Cham, Switzerland: Springer International Publishing. doi: 10.1007/978-3-319-53880-8_8

Small cells for big ideas: the cytotoxic podophyllotoxin and the long journey in discovering its biosynthetic pathway

2015

Journal Article

Podophyllotoxin production by cell cultures of Linum thracicum ssp. Thracicum degen elicited with methyl jasmonate and salicylic acid

Sasheva, Pavlina and Ionkova, Iliana (2015). Podophyllotoxin production by cell cultures of Linum thracicum ssp. Thracicum degen elicited with methyl jasmonate and salicylic acid. Comptes Rendus de L'Academie Bulgare des Sciences, 68 (7), 883-888.

Podophyllotoxin production by cell cultures of Linum thracicum ssp. Thracicum degen elicited with methyl jasmonate and salicylic acid

2015

Journal Article

Methyl jasmonate induces enhanced podophyllotoxin production in cell cultures of thracian flax (linum thracicum ssp. thracicum)

Sasheva, Pavlina, Ionkova, Iliana and Stoilova, Nadezhda (2015). Methyl jasmonate induces enhanced podophyllotoxin production in cell cultures of thracian flax (linum thracicum ssp. thracicum). Natural Product Communications, 10 (7), 1225-1228. doi: 10.1177/1934578x1501000722

Methyl jasmonate induces enhanced podophyllotoxin production in cell cultures of thracian flax (linum thracicum ssp. thracicum)

2014

Journal Article

Cytotoxic effect of the biotechnologically-derived justicidin B on human lymphoma cells

Ilieva, Y., Zhelezova, I., Atanasova, T., Zaharieva, M. M., Sasheva, P., Ionkova, I. and Konstantinov, S. (2014). Cytotoxic effect of the biotechnologically-derived justicidin B on human lymphoma cells. Biotechnology Letters, 36 (11), 2177-2183. doi: 10.1007/s10529-014-1612-4

Cytotoxic effect of the biotechnologically-derived justicidin B on human lymphoma cells

2013

Journal Article

Study of primary photosynthetic reactions in winter wheat cultivars after cold hardening and freezing. effect of salicylic acid

Sasheva, P., Yordanova, R., Janda, T., Szalai, G. and Maslenkova, L. (2013). Study of primary photosynthetic reactions in winter wheat cultivars after cold hardening and freezing. effect of salicylic acid. Bulgarian Journal of Agricultural Science, 19 (SUPPL. 2), 45-48.

Study of primary photosynthetic reactions in winter wheat cultivars after cold hardening and freezing. effect of salicylic acid

2013

Journal Article

Biotechnological production of podophyllotoxin and podophyllotoxinrelated lignans in cultures of Linum thracicum degen

Sasheva, Pavlina, Letkarska, Gergana and Ionkova, Iliana (2013). Biotechnological production of podophyllotoxin and podophyllotoxinrelated lignans in cultures of Linum thracicum degen. Comptes Rendus de L'Academie Bulgare des Sciences, 66 (10), 1445-1450.

Biotechnological production of podophyllotoxin and podophyllotoxinrelated lignans in cultures of Linum thracicum degen

2013

Journal Article

Linum narbonense: a new valuable tool for biotechnological production of a potent anticancer lignan Justicidine B

Ionkova, Iliana, Sasheva, Pavlina, Ionkov, Todor and Momekov, Georgi (2013). Linum narbonense: a new valuable tool for biotechnological production of a potent anticancer lignan Justicidine B. Pharmacognosy Magazine, 9 (33), 39-44. doi: 10.4103/0973-1296.108138

Linum narbonense: a new valuable tool for biotechnological production of a potent anticancer lignan Justicidine B

2013

Journal Article

Combined control of the bioprocess for production of C-glycosylflavones from Linum Thracicum in bioreactor

Ionkov, Todor, Sasheva, Pavlina, Ionkova, Iliana, Bucar, Franz and Milanova, Desislava (2013). Combined control of the bioprocess for production of C-glycosylflavones from Linum Thracicum in bioreactor. Comptes Rendus de L'Academie Bulgare des Sciences, 66 (1), 139-146.

Combined control of the bioprocess for production of C-glycosylflavones from Linum Thracicum in bioreactor

2012

Journal Article

Improvement bioreactor production of cytotoxic saponins in Astragalus membranaceus by combined control of the bioprocess

Ionkov, Todor, Ionkova, Iliana, Momekov, Georgi and Sasheva, Pavlina (2012). Improvement bioreactor production of cytotoxic saponins in Astragalus membranaceus by combined control of the bioprocess. Comptes Rendus de L'Academie Bulgare des Sciences, 65 (10), 1447-1454.

Improvement bioreactor production of cytotoxic saponins in Astragalus membranaceus by combined control of the bioprocess

2010

Journal Article

Study of the behaviour of antioxidant enzymes in the response to hardening and freezing stress in two wheat (triticum aestivum l.) varieties

Sasheva, Pavlina, Szalai, Gabriella, Janda, Tibor and Popova, Losanka (2010). Study of the behaviour of antioxidant enzymes in the response to hardening and freezing stress in two wheat (triticum aestivum l.) varieties. Comptes Rendus de L'Academie Bulgare des Sciences, 63 (12), 1733-1740.

Study of the behaviour of antioxidant enzymes in the response to hardening and freezing stress in two wheat (triticum aestivum l.) varieties

Funding

Current funding

  • 2025 - 2026
    Quantum-enabled detection of invasive pathogens for improved biosecurity
    Data Effects Pty Ltd
    Open grant
  • 2024 - 2027
    Quantum biomolecular assays for anti-doping control
    Quantum 2032 Challenge Program
    Open grant
  • 2023 - 2026
    Using molecular optomechanics to understand proteins at the quantum level
    National Intelligence Postdoctoral Grants ONI
    Open grant

Supervision

Availability

Dr Pavlina Naydenova is:
Not available for supervision

Supervision history

Current supervision

Media

Enquiries

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