Professor Bryan Fry
Professor

Bryan Fry

Email: 
Phone: 
+61 7 336 58515
Mobile: 
0400 193 182

Background

Venoms play a range of adaptive roles in the animal kingdom from predation to defense to competitor deterrence. Remarkably, despite their biological importance and uniqueness, the evolution of venom systems is poorly understood. New insights into the evolution of venom systems and the importance of the associated toxins cannot be advanced without recognition of the true biochemical, ecological, morphological and pharmacological diversity of venoms and associated venom systems. A major limitation has been the very narrow taxonomical range studied. Entire groups of venomous animals remain virtually unstudied. My research is inherently interdisciplinary, integrating ecological, evolutionary, and functional genomics approaches in order to understand the evolution of venom systems. Studies range from discovering the shock-inducing hypotensive and anticoagulant venom of the iconic Komodo Dragon through to exploring the unique temperature specific adaptations of Antarctic octopus venoms.

Availability

Professor Bryan Fry is:
Available for supervision
Media expert

Fields of research

Biological Sciences Medicinal and biomolecular chemistry Zoology

Qualifications

  • Doctor of Philosophy, The University of Queensland

Search Professor Bryan Fry’s works on UQ eSpace

240 works between 1998 and 2026
All (240) Journal Article (221) Other Outputs (1) Conference Publication (13) Book Chapter (5)

201 - 220 of 240 works

2013

Journal Article

Venom proteomic characterization and relative antivenom neutralization of two medically important Pakistani elapid snakes (Bungarus sindanus and Naja naja)

Ali, Syed A., Yang, Daryl C., Jackson, Timothy N. W., Undheim, Eivind A. B., Koludarov, Ivan, Wood, Kelly, Jones, Alun, Hodgson, Wayne C., McCarthy, Sean, Ruder, Tim and Fry, Bryan G. (2013). Venom proteomic characterization and relative antivenom neutralization of two medically important Pakistani elapid snakes (Bungarus sindanus and Naja naja). Journal of Proteomics, 89, 15-23. doi: 10.1016/j.jprot.2013.05.015

Venom proteomic characterization and relative antivenom neutralization of two medically important Pakistani elapid snakes (Bungarus sindanus and Naja naja)

2013

Journal Article

Dracula's children: molecular evolution of vampire bat venom

Low, Dolyce H. W., Sunagar, Kartik, Undheim, Eivind A. B., Ali, Syed A., Alagon, Alejandro C., Ruder, Tim, Jackson, Timothy N. W., Gonzalez, Sandy Pineda, King, Glenn F., Jones, Alun, Antunes, Agostinho and Fry, Bryan G. (2013). Dracula's children: molecular evolution of vampire bat venom. Journal of Proteomics, 89, 95-111. doi: 10.1016/j.jprot.2013.05.034

Dracula's children: molecular evolution of vampire bat venom

2013

Journal Article

Squeezers and leaf-cutters: differential diversification and degeneration of the venom system in toxicoferan reptiles

Fry, Bryan G., Undheim, Eivind A. B., Ali, Syed A., Jackson, Timothy N. W., Debono, Jordan, Scheib, Holger, Ruder, Tim, Morgenstern, David, Cadwallader, Luke, Whitehead, Darryl, Nabuurs, Rob, van der Weerd, Louise, Vidal, Nicolas, Roelants, Kim, Hendrikx, Iwan, Gonzalez, Sandy Pineda, Koludarov, Ivan, Jones, Alun, King, Glenn F., Antunes, Agostinho and Sunagar, Kartik (2013). Squeezers and leaf-cutters: differential diversification and degeneration of the venom system in toxicoferan reptiles. Molecular and Cellular Proteomics, 12 (7), 1881-1899. doi: 10.1074/mcp.M112.023143

Squeezers and leaf-cutters: differential diversification and degeneration of the venom system in toxicoferan reptiles

2013

Journal Article

Molecular phylogeny and evolution of the proteins encoded by coleoid (cuttlefish, octopus, and squid) posterior venom glands

Ruder, Tim, Sunagar, Kartik, Undheim, Eivind A. B., Ali, Syed A., Wai, Tak-Cheung, Low, Dolyce H. W., Jackson, Timothy N. W., King, Glenn F., Antunes, Agostinho and Fry, Bryan G. (2013). Molecular phylogeny and evolution of the proteins encoded by coleoid (cuttlefish, octopus, and squid) posterior venom glands. Journal of Molecular Evolution, 76 (4), 192-204. doi: 10.1007/s00239-013-9552-5

Molecular phylogeny and evolution of the proteins encoded by coleoid (cuttlefish, octopus, and squid) posterior venom glands

2013

Journal Article

Response to "Replies to Fry et al. (Toxicon 2012, 60/4, 434-448). Part B. Analyses of squamate reptile oral glands and their products: A call for caution in formal assignment of terminology designating biological function"

Jackson, Timothy N. W., Casewell, Nicholas R. and Fry, Bryan G. (2013). Response to "Replies to Fry et al. (Toxicon 2012, 60/4, 434-448). Part B. Analyses of squamate reptile oral glands and their products: A call for caution in formal assignment of terminology designating biological function". Toxicon, 64, 113-115. doi: 10.1016/j.toxicon.2012.12.023

Response to "Replies to Fry et al. (Toxicon 2012, 60/4, 434-448). Part B. Analyses of squamate reptile oral glands and their products: A call for caution in formal assignment of terminology designating biological function"

2013

Journal Article

Response to "Replies to Fry et al. (Toxicon 2012, 60/4, 434-448). Part A. Analyses of squamate reptile oral glands and their products: A call for caution in formal assignment of terminology designating biological function"

Jackson, Timothy N. W., Casewell, Nicholas R. and Fry, Bryan G. (2013). Response to "Replies to Fry et al. (Toxicon 2012, 60/4, 434-448). Part A. Analyses of squamate reptile oral glands and their products: A call for caution in formal assignment of terminology designating biological function". Toxicon, 64, 106-112. doi: 10.1016/j.toxicon.2012.11.006

Response to "Replies to Fry et al. (Toxicon 2012, 60/4, 434-448). Part A. Analyses of squamate reptile oral glands and their products: A call for caution in formal assignment of terminology designating biological function"

2013

Journal Article

Differential evolution and neofunctionalization of snake venom metalloprotease domains

Brust, Andreas, Sunagar, Kartik, Eivind Undheim, Vetter, Irina, Yang, Daryl C., Casewell, Nicholas R., Ruder, Tim, Jackson, Timothy N. W., Koludarov, Ivan, Alewood, Paul F., Hodgson, Wayne C., Lewis, Richard J., King, Glenn F., Antunes, Agostinho, Hendrikx, Iwan and Fry, Bryan G. (2013). Differential evolution and neofunctionalization of snake venom metalloprotease domains. Molecular and Cellular Proteomics, 12 (3), 651-663. doi: 10.1074/mcp.M112.023135

Differential evolution and neofunctionalization of snake venom metalloprotease domains

2013

Journal Article

Anaerobic and aerobic bacteriology of the saliva and gingiva from 16 captive Komodo dragons (Varanus Komodoensis): New implications for the bacteria as venom model

Goldstein, Ellie J. C., Tyrrell, Kerin L., Citron, Diane M., Cox, Cathleen R., Recchio, Ian M., Okimoto, Ben, Bryja, Judith and Fry, Bryan G. (2013). Anaerobic and aerobic bacteriology of the saliva and gingiva from 16 captive Komodo dragons (Varanus Komodoensis): New implications for the bacteria as venom model. Journal of Zoo and Wildlife Medicine, 44 (2), 262-272. doi: 10.1638/2012-0022R.1

Anaerobic and aerobic bacteriology of the saliva and gingiva from 16 captive Komodo dragons (Varanus Komodoensis): New implications for the bacteria as venom model

2013

Journal Article

Evolution stings: the origin and diversification of scorpion toxin peptide scaffolds

Sunagar, Kartik, Undheim, Eivind A. B., Chan, Angelo H. C., Koludarov, Ivan, Munoz-Gomez, Sergio A., Antunes, Agostinho and Fry, Bryan G. (2013). Evolution stings: the origin and diversification of scorpion toxin peptide scaffolds. Toxins, 5 (12), 2456-2487. doi: 10.3390/toxins5122456

Evolution stings: the origin and diversification of scorpion toxin peptide scaffolds

2013

Journal Article

Molecular evidence that the deadliest sea snake Enhydrina schistosa (Elapidae: Hydrophiinae) consists of two convergent species

Ukuwela, Kanishka D. B., de Silva, Anslem, Mumpuni, Fry, Bryan G., Lee, Michael S. Y. and Sanders, Kate L. (2013). Molecular evidence that the deadliest sea snake Enhydrina schistosa (Elapidae: Hydrophiinae) consists of two convergent species. Molecular Phylogenetics and Evolution, 66 (1), 262-269. doi: 10.1016/j.ympev.2012.09.031

Molecular evidence that the deadliest sea snake Enhydrina schistosa (Elapidae: Hydrophiinae) consists of two convergent species

2013

Journal Article

Venom down under: dynamic evolution of Australian elapid snake toxins

Jackson, Timothy N. W., Sunagar, Kartik, Undheim, Eivind A. B., Koludarov, Ivan, Chan, Angelo H. C., Sanders, Kate, Ali, Syed A., Hendrikx, Iwan, Dunstan, Nathan and Fry, Bryan G. (2013). Venom down under: dynamic evolution of Australian elapid snake toxins. Toxins, 5 (12), 2621-2655. doi: 10.3390/toxins5122621

Venom down under: dynamic evolution of Australian elapid snake toxins

2013

Journal Article

Three-fingered RAVERs: Rapid Accumulation of Variations in Exposed Residues of snake venom toxins

Sunagar, Kartik, Jackson, Timothy N. W., Undheim, Elvind A. B., Ali, Syed A., Antunes, Agostinho and Fry, Bryan G. (2013). Three-fingered RAVERs: Rapid Accumulation of Variations in Exposed Residues of snake venom toxins. Toxins, 5 (11), 2172-2208. doi: 10.3390/toxins5112172

Three-fingered RAVERs: Rapid Accumulation of Variations in Exposed Residues of snake venom toxins

2013

Journal Article

A proteomics and transcriptomics investigation of the venom from the Barychelid spider Trittame loki (brush-foot trapdoor)

Undheim, Eivind A. B., Sunagar, Kartik, Herzig, Volker, Kely, Laurence, Low, Dolyce H. W., Jackson, Timothy N. W., Jones, Alun, Kurniawan, Nyoman, King, Glenn F., Ali, Syed A., Antunes, Agostino, Ruder, Tim and Fry, Bryan G. (2013). A proteomics and transcriptomics investigation of the venom from the Barychelid spider Trittame loki (brush-foot trapdoor). Toxins, 5 (12), 2488-2503. doi: 10.3390/toxins5122488

A proteomics and transcriptomics investigation of the venom from the Barychelid spider Trittame loki (brush-foot trapdoor)

2013

Journal Article

Atractaspis aterrima toxins: The first insight into the molecular evolution of venom in side-stabbers

Terrat, Yves, Sunagar, Kartik, Fry, Bryan G., Jackson, Timothy N. W., Scheib, Holger, Fourmy, Rudy, Verdenaud, Maria, Blanchet, Guillaume, Antunes, Agostinho and Ducancel, Frederic (2013). Atractaspis aterrima toxins: The first insight into the molecular evolution of venom in side-stabbers. Toxins, 5 (11), 1948-1964. doi: 10.3390/toxins5111948

Atractaspis aterrima toxins: The first insight into the molecular evolution of venom in side-stabbers

2012

Journal Article

Complex cocktails: the evolutionary novelty of venoms

Casewell, Nicholas R., Wuster, Wolfgang, Vonk, Freek J., Harrison, Robert A. and Fry, Bryan G. (2012). Complex cocktails: the evolutionary novelty of venoms. Trends In Ecology & Evolution, 28 (4), 219-229. doi: 10.1016/j.tree.2012.10.020

Complex cocktails: the evolutionary novelty of venoms

2012

Journal Article

Structural and molecular diversification of the Anguimorpha lizard mandibular venom gland system in the arboreal species Abronia graminea

Koludarov, Ivan, Sunagar, Kartik, Undheim, Eivind A. B., Jackson, Timothy N. W., Ruder, Tim, Whitehead, Darryl, Saucedo, Alejandro C., Roberto Mora, G., Alagon, Alejandro C., King, Glenn, Antunes, Agostinho and Fry, Bryan G. (2012). Structural and molecular diversification of the Anguimorpha lizard mandibular venom gland system in the arboreal species Abronia graminea. Journal of Molecular Evolution, 75 (5-6), 168-183. doi: 10.1007/s00239-012-9529-9

Structural and molecular diversification of the Anguimorpha lizard mandibular venom gland system in the arboreal species Abronia graminea

2012

Journal Article

Differential Evolution and Neofunctionalization of Snake Venom Metalloprotease Domains (vol 12, pg 651, 2013)

Brust, Andreas, Sunagar, Kartik, Undheim, Eivind A. B., Vetter, Irina, Yang, Daryl C., Casewell, Nicholas R., Jackson, Timothy N. W., Koludarov, Ivan, Alewood, Paul F., Hodgson, Wayne C., Lewis, Richard J., King, Glenn F., Antunes, Agostinho, Hendrikx, Iwan and Fry, Bryan G. (2012). Differential Evolution and Neofunctionalization of Snake Venom Metalloprotease Domains (vol 12, pg 651, 2013). Molecular & Cellular Proteomics, 12 (5), 1488-1488. doi: 10.1074/mcp.M112.023135

Differential Evolution and Neofunctionalization of Snake Venom Metalloprotease Domains (vol 12, pg 651, 2013)

2012

Journal Article

Toxinology of venoms from five Australian lesser known elapid snakes

Pycroft, Kyle, Fry, Bryan G., Isbister, Geoffrey K., Kuruppu, Sanjaya, Lawrence, Josie, Smith, A. Ian and Hodgson, Wayne C. (2012). Toxinology of venoms from five Australian lesser known elapid snakes. Basic & Clinical Pharmacology & Toxicology, 111 (4), 268-274. doi: 10.1111/j.1742-7843.2012.00907.x

Toxinology of venoms from five Australian lesser known elapid snakes

2012

Journal Article

Molecular evidence for an Asian origin of monitor lizards followed by Tertiary dispersals to Africa and Australasia

Vidal, Nicolas, Marin, Julie, Sassi, Julia, Battistuzzi, Fabia U., Donnellan, Steve, Fitch, Alison J., Fry, Bryan G., Vonk, Freek J., de la Vega, Ricardo C. Rodriguez, Couloux, Arnaud and Hedges, S. Blair (2012). Molecular evidence for an Asian origin of monitor lizards followed by Tertiary dispersals to Africa and Australasia. Biology Letters, 8 (5), 853-855. doi: 10.1098/rsbl.2012.0460

Molecular evidence for an Asian origin of monitor lizards followed by Tertiary dispersals to Africa and Australasia

2012

Journal Article

The structural and functional diversification of the Toxicofera reptile venom system

Fry, Bryan G., Casewell, Nicholas R., Wuester, Wolfgang, Vidal, Nicolas, Young, Bruce and Jackson, Timothy N. W. (2012). The structural and functional diversification of the Toxicofera reptile venom system. Toxicon, 60 (4), 434-448. doi: 10.1016/j.toxicon.2012.02.013

The structural and functional diversification of the Toxicofera reptile venom system

Current funding

  • 2025 - 2027
    Adaptive Biotoxicology Lab (Venom Evolution Lab)
    The University of Queensland in America, Inc
    Open grant

Past funding

  • 2021 - 2024
    Evolutionary models and biodiscovery tools from neurotoxic snake venoms
    ARC Discovery Projects
    Open grant
  • 2020 - 2021
    Replacing the use of animals for the study of the alpha-5 subunit of nicotinic acetylcholine receptors and to probe the drug potential of novel ligands for colitis and anti-smoking
    The MAWA Trust
    Open grant
  • 2020 - 2021
    An integrated, multi-node bio-layer interferometry facility
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2019 - 2022
    Functional evolution and therapeutic potential of snake venom coagulotoxins
    ARC Discovery Projects
    Open grant
  • 2019
    Imaging Mass Spectrometry at Higher Mass Resolution
    UQ Research Facilities Infrastructure Grants
    Open grant
  • 2018 - 2019
    Coagulotoxic effects of Brazilian snake venoms: Role in adaptive evolution and human pathophysiological implications
    UQ-FAPESP Strategic Research Fund SPRINT
    Open grant
  • 2018
    Multichannel peptide synthesiser to accelerate UQ's biodiscovery pipeline and peptide drug development programs
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017
    Deep Protein Sequencing, Structure and Quantification Facility
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2016
    Integrative blood coagulation research core facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2016
    Patch-clamp electrophysiology platform for drug and insecticide discovery
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2016
    Evolution of Sea Snakes in Australia's Gulf of Carpentaria
    National Geographic Society
    Open grant
  • 2015
    A sensitive, high resolution QTOF mass spectrometer with nanoUPLC system for qualitative and quantitative biomolecule analysis.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015
    Beyond genomes, transcriptomes and proteomes: high throughput analysis of gene and protein expression and function
    UQ Major Equipment and Infrastructure
    Open grant
  • 2014 - 2017
    Imaging the world of miniature venomous arthropods
    ARC Linkage Projects
    Open grant
  • 2014 - 2016
    Fish venom as a model system for the molecular evolution of defensive toxins
    ARC Discovery Projects
    Open grant
  • 2013 - 2014
    Investigation of the venom of two endangered snakes
    Australian Geographic Pty Limited
    Open grant
  • 2013
    High throughput electrophysiology platform
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013 - 2014
    ResTeach 2013 0.05 FTE School of Biological Sciences
    UQ ResTeach
    Open grant
  • 2013
    UQ Travel Awards Category 1 - Dr Nicholas Casewell
    UQ Travel Grants Scheme
    Open grant
  • 2011 - 2014
    The only poisonous primates: the ecological and behaviour context of slow loris venom.
    Oxford Brookes University
    Open grant
  • 2011 - 2012
    Molecular toxinology of Australia's lesser known venomous snakes
    ARC Discovery Projects
    Open grant
  • 2011 - 2015
    Adaptive evolution of coleoid (cuttlefish, octopus, squid) venoms
    ARC Future Fellowships
    Open grant
  • 2011
    Evolutionary venomics: Venom system diversification in the animal kingdom
    ARC Discovery Projects
    Open grant

Availability

Professor Bryan Fry is:
Available for supervision

Looking for a supervisor? Read our advice on how to choose a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    Evolutionary and clinical implications of differential pathophysiological effects of rattlesnake venoms upon blood coagulation, cell function, and nerve transmission.

    Principal Advisor

    Other advisors: Dr Andrew Walker

  • Doctor Philosophy

    Integrated analysis of scorpion venom and morphological evolution

    Principal Advisor

    Other advisors: Professor Glenn King, Dr Sam Robinson

  • Doctor Philosophy

    Anacondas as sentinel species for accumulation of oil spill heavy metals into the food web

    Principal Advisor

    Other advisors: Professor Jianxin Zhao

  • Master Philosophy

    Comparing Clotting Factor Activation in Bothrops species

    Principal Advisor

    Other advisors: Dr Andrew Walker

Completed supervision

Enquiries

Contact Professor Bryan Fry directly for media enquiries about:

  • Animal venoms
  • Antivenoms
  • Biodiscovery
  • Drug design
  • Venom

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