
Overview
Background
I currently have a number of research interests, both in Biomedical and well as in Teaching-Focussed Research.
Biomedical projects have traditionally been done with collaborators, and some of the projects have included:
- mechanisms of action of animal venoms and toxins, and we have used the organ bath laboratory and pharmacologoical techniques as bioassays
- study of bitter tasting compounds on pig digestive processes, to better understand activation of bitter taste receptors in vivo
Teaching-focussed interested are around university student behaviour with regard to learning activities and engagement. Universities around the world are grappling with shifts in effective and engaging educational strategies, as well as student expectations, in their delivery of content. In an age where students can do on-line courses at universities far from Australia, academics are carefully considering student engagement and success here at UQ.
- Lecture slots currently have the bulk of contact hours in most courses, with ~39 lectures per course across a semester. These are largely recorded and used as a teaching resource. Student attendance to the traditional lecture spaces has decreased significantly across all campuses, with a UQ average of ~60% across all courses. This type of analysis has recently led to UQ offering smaller venues for larger courses in which there have been patterns of partial attendance.
- My work seeks to better understand what motivates students to attend these spaces in their traditional sense and in the transition to an increasing number of flipped classroom models and blended learning, where the academics are less on the stage, and are instead facilitating activities for learning, while students will be engaged in learning content largely outside the lecture slots.
- "Embracing the Unknown" Experience in third year science courses is also an interest, in which research work and its associated uncertainties cause varying levels of anxiety in some students. Best understanding this process and supporting students through it is also an interest of mine.
Availability
- Dr Mary-Louise Roy Manchadi is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, Northwestern University
Works
Search Professor Mary-Louise Roy Manchadi’s works on UQ eSpace
2024
Journal Article
Utilizing systems genetics to enhance understanding into molecular targets of skin cancer
Kim, Minjae J., Kulkarni, Vishnutheertha, Goode, Micah A., Hernandez, Jacob, Graham, Sean, Sivesind, Torunn E. and Manchadi, Mary‐Louise (2024). Utilizing systems genetics to enhance understanding into molecular targets of skin cancer. Experimental Dermatology, 33 (3) e15043, 1-9. doi: 10.1111/exd.15043
2022
Book Chapter
The virtual microscope: tracing knowledge of human microstructure through digital images
Aland, R. Claire, Shepherd, Nicole, Swyny, Belinda and Manchadi, Mary-Louise Roy (2022). The virtual microscope: tracing knowledge of human microstructure through digital images. Making sense of medicine: materiality and the reproduction of medical knowledge. (pp. 271-280) Bristol, United Kingdom: Intellect Books. doi: 10.1386/9781789385779_19
2022
Conference Publication
Using action learning to develop a model for inclusive teaching in a COVID-split cohort
Aland, Claire, Oancea, Iulia, Midwinter, Mark, Pillai, Suja, Manchadi, Mary-Louise, Reichelt, Melissa and Wu, Sherry (2022). Using action learning to develop a model for inclusive teaching in a COVID-split cohort. 26th Annual International Association for Medical Science Educators, Denver, CO, United States, 4-7 June 2022.
2017
Journal Article
The impact of periconceptional alcohol exposure on fat preference and gene expression in the mesolimbic reward pathway in adult rat offspring
Dorey, E. S., Cullen, C. L., Lucia, D., Mah, K. M., Manchadi, M.-L. Roy, Muhlhausler, B. S. and Moritz, K. M. (2017). The impact of periconceptional alcohol exposure on fat preference and gene expression in the mesolimbic reward pathway in adult rat offspring. Journal of Developmental Origins of Health and Disease, 9 (2), 223-231. doi: 10.1017/S2040174417000824
2017
Journal Article
Enter the dragon: the dynamic and multifunctional evolution of anguimorpha lizard venoms
Koludarov, Ivan, Jackson, Timothy N. W., op den Brouw, Bianca, Dobson, James, Dashevsky, Daniel, Arbuckle, Kevin, Clemente, Christofer J., Stockdale, Edward J., Cochran, Chip, Debono, Jordan, Stephens, Carson, Panagides, Nadya, Li, Bin, Manchadi, Mary-Louise Roy, Violette, Aude, Fourmy, Rudy, Hendrikx, Iwan, Nouwens, Amanda, Clements, Judith, Martelli, Paolo, Kwok, Hang Fai and Fry, Bryan G. (2017). Enter the dragon: the dynamic and multifunctional evolution of anguimorpha lizard venoms. Toxins, 9 (8) 242, 242. doi: 10.3390/toxins9080242
2016
Conference Publication
Bitter compounds delayed gastric emptying and induced intestinal smooth muscle relaxation in a pig model
Fu, Minghai, Manchadi, Mary-Louise, De Jager, Nadia, Val-Laillet, David, Guerin, Sylvie and Roura, Eugeni (2016). Bitter compounds delayed gastric emptying and induced intestinal smooth muscle relaxation in a pig model. 17th International Symposium on Olfaction and Taste (ISOT), Yokohama Japan, 5-9 June 2016. United Kingdom: Oxford University Press.
2015
Journal Article
Modulation of smooth muscle relaxation by short and long carbon based chemicals
Poyton, Curtis Nicholas, Cheesman, Matthew James, Manchadi, Mary-Louise and Lavidis, Nickolas Anastasios (2015). Modulation of smooth muscle relaxation by short and long carbon based chemicals. Pharmacognosy Communications, 5 (4), 250-256. doi: 10.5530/pc.2015.4.6
2015
Journal Article
Effects of lavender and linalool on neurotransmission and contraction of smooth muscle
Poyton, Curtis, Manchadi, Mary-Louise, Cheesman, Matthew and Lavidis, Nickolas (2015). Effects of lavender and linalool on neurotransmission and contraction of smooth muscle. Pharmacognosy Communications, 5 (3), 217-225. doi: 10.5530/pc.2015.3.7
2015
Journal Article
Student Interaction with a Computer Tablet Exam Application Replicating the Traditional Paper Exam
Cheesman, Matthew J., Chunduri, Prasad, Manchadi, Mary Louise, Colthorpe, Kay and Matthews, Ben (2015). Student Interaction with a Computer Tablet Exam Application Replicating the Traditional Paper Exam. Mobile Computing, 4, 10-21. doi: 10.14355/mc.2015.04.002
2015
Book Chapter
Research methods
Fry, B. G., Undheim, E. A. B., Jackson, T. N. W., Georgieva, D., Vetter, I., Calvete, J. J., Schieb, H., Cribb, B. W., Yang, D. C., Daly, N. L., Manchadi, M. L. Roy, Gutierrez, J. M., Roelants, K., Lomonte, B., Nicholson, G. M., Dziemborowicz, S., Lavergne, V., Ragnarsson, L., Rash, L. D., Mobli, M., Hodgson, W. C., Casewell, N. R., Nouwens, A., Wagstaff, S. C., Ali, S. A., Whitehead, D. L., Herzig, V., Monagle, P., Kurniawan, N. D. ... Sunagar, K. (2015). Research methods. Venomous reptiles and their toxins: evolution, pathophysiology and biodiscovery. (pp. 153-214) New York, NY, United States: Oxford University Press.
2014
Journal Article
Implementation of a Virtual Laboratory Practical Class (VLPC) module in pharmacology education
Cheesman, Matthew J., Chen, Steven, Manchadi, Mary-Louise, Jacob, Teague, Minchin, Rodney F. and Tregloan, Peter A. (2014). Implementation of a Virtual Laboratory Practical Class (VLPC) module in pharmacology education. Pharmacognosy Communications, 4 (1), 2-10. doi: 10.5530/pc.2014.1.2
2014
Conference Publication
Analysis of student behavioural patterns in the use of a virtual laboratory: A comparison of cohorts from two different disciplines
Cheesman, Matthew, Williams, Mark, Chunduri, Prasad, Manchadi, Mary-Louise and Tregloan, Peter (2014). Analysis of student behavioural patterns in the use of a virtual laboratory: A comparison of cohorts from two different disciplines. Australian Conference on Science and Mathematics Education, Sydney NSW Australia, 29-30 September 2014. ACSME.
2013
Journal Article
Functional characterization on invertebrate and vertebrate tissues of tachykinin peptides from octopus venoms
Ruder, Tim, Ali, Syed Abid, Ormerod, Kiel, Brust, Andreas, Roymanchadi, Mary-Louise, Ventura, Sabatino, Undheim, Eivind A. B., Jackson, Timothy N. W., Mercier, A. Joffre, King, Glenn F., Alewood, Paul F. and Fry, Bryan G. (2013). Functional characterization on invertebrate and vertebrate tissues of tachykinin peptides from octopus venoms. Peptides, 47, 71-76. doi: 10.1016/j.peptides.2013.07.002
1997
Journal Article
A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG
Rampe, David, Roy, Mary-Louise, Dennis, Adrienne and Brown, Arthur M. (1997). A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG. FEBS Letters, 417 (1), 28-32. doi: 10.1016/s0014-5793(97)01249-0
1996
Journal Article
Manipulation of the delayed rectifier Kv1.5 potassium channel in glial cells by antisense oligodeoxynucleotides
Roy, Mary Louise, Saal, Daniel, Perney, Teresa, Sontheimer, Harald, Waxman, Stephen G. and Kaczmarek, Leonard K. (1996). Manipulation of the delayed rectifier Kv1.5 potassium channel in glial cells by antisense oligodeoxynucleotides. Glia, 18 (3), 177-184. doi: 10.1002/(sici)1098-1136(199611)18:33.0.co;2-x
1996
Journal Article
Regulation by spermine of native inward rectifier K+ channels in RBL-1 cells
Bianchi, Laura, Roy, Mary-Louise, Taglialatela, Maurizio, Lundgren, David W., Brown, Arthur M. and Ficker, Eckhard (1996). Regulation by spermine of native inward rectifier K+ channels in RBL-1 cells. Journal of Biological Chemistry, 271 (11), 6114-6121. doi: 10.1074/jbc.271.11.6114
1995
Journal Article
Sodium channels and GABAA receptor-channel complex as targets of environmental toxicants
Narahashi, Toshio, Carter, Donald B., Frey, Joseph, Ginsburg, Kenneth, hamilton, Beverly J., Nagata, Keiichi, Roy, Mary Louise, Song, Jin-ho and Tatebayashi, Hideharu (1995). Sodium channels and GABAA receptor-channel complex as targets of environmental toxicants. Toxicology Letters, 82-83 (C), 239-245. doi: 10.1016/0378-4274(95)03482-x
1994
Journal Article
Single-channel analysis of tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels in rat dorsal root ganglion neurons
Roy, Mary Louise, Reuveny, Eitan and Narahashi, Toshio (1994). Single-channel analysis of tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels in rat dorsal root ganglion neurons. Brain Research, 650 (2), 341-346. doi: 10.1016/0006-8993(94)91803-1
1994
Book Chapter
Contributors to Volume 19
Akaike, Norio, Albuquerque, Edson X., Alford, Simon, Alkondon, Manickavasagom, Angelides, Kimon J., Bangalore, Ramesh, Castro, Newton G., Chiu, S.Y., Collingridge, Graham L., Drewe, John A., Eberwine, James, Farley, Jerry M., Ferrer-Montiel, Antonio V., Glaum, Steven R., Grove, Anne, Harata, Nobutoshi, Hartmann, Hali A., Henzi, Victor, Hicks, Barry W., Kass, Robert S., Kirsch, Glenn E., Lester, Henry A., Macdermott, Amy B., Macdonald, John F., Montal, Mauricio, Montes, Joseph G., Narahashi, Toshio, Pereira, Edna F.R., Puro, Donald G. ... Wilson, C.J. (1994). Contributors to Volume 19. Ion channels of excitable cells. (pp. vii-x) Amsterdam, Netherlands: Elsevier. doi: 10.1016/b978-0-12-185287-0.50004-1
1994
Book Chapter
Sodium channels of rat dorsal root ganglion neurons
Roy, Mary Louise and Narahashi, Toshio (1994). Sodium channels of rat dorsal root ganglion neurons. Ion channels of excitable cells. (pp. 21-38) edited by Toshio Narahashi. Amsterdam, Netherlands: Elsevier. doi: 10.1016/b978-0-12-185287-0.50008-9
Funding
Past funding
Supervision
Availability
- Dr Mary-Louise Roy Manchadi is:
- Available for supervision
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Available projects
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What are the motivators for attending lectures and other learning activities, directly assessed or not?
In association with the Spaces Management team at UQ, we have access to accurate student numbers across the university so as to track lecture attendance based on body heat entering and exiting lecture venues. Aligning the use of these sensors with course, lecturer and topic will give a rich qualitative data set. In addition to this, surveys will be done with key courses across the university for those which have high attendance and those with low – and drivers identified and shared with the Course Coordinators, along with such learnings being used to inform the Teaching and Learning Community.
A former Honours student has shown that the biggest motivator for lecture attendance between professional, science and therapies students is feeling part of a student cohort. As the professional and therapies students tend to do all of the same courses through their degree, the bonds of friendship and community can run deep and being together with friends in educational spaces has been identified as a main driver for attendance. Science students, however, do not have this profile, as there can be wide variation in courses chosen after first year.
I have data from second and third year science students which asks them to reflect on their experiences as a university student in learning spaces, and such data can be analysed for quality statement and frequency of responses to better inform academics around what students are actually experiencing.
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“Embracing the Unknown” Experience
In our third year Pharmacology course for Science students (BIOM3401), we have a practical called “Identification of Unknowns”, in which students are given an unknown drug(s), and they are asked to design experiments around identifying which drug class this might be over 2-3 weeks. This has caused some minor (and major!) anxiety in some students, as the activity is assessed as a lab report, with marks being awarded for the arguments made, and not the correct identification.
Students were surveyed before and after the experiments to capture their thinking and concerns, and these data are available for thematic analysis. Such analysis can enable future students to be better supported, or even less supported, depending upon feedback.
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To Lecture or not to Lecture….that is the question…
We have meta-learning data from second and third year science students about their habits, preferred types of learning and access to information, and their perceptions of live lectures. This data can be analysed thematically, and thus contribute meaningfully to the development of blended learning courses.
Supervision history
Completed supervision
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2023
Doctor Philosophy
Therapeutic options for divergent snake venom.
Associate Advisor
Other advisors: Professor Bryan Fry
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2017
Doctor Philosophy
Dietary Manipulation of Feed Intake in Pigs by Bitter Compounds
Associate Advisor
Other advisors: Professor Eugeni Roura
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Media
Enquiries
Contact Dr Mary-Louise Roy Manchadi directly for media enquiries about:
- Drug effects on nervous system
- Drugs - effects on diseased conditions
- Drugs - effects on health
- Nervous system - impact of drugs
- Neuroscience
- Pharmacology
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