Professor Bryan Fry
Professor

Bryan Fry

Email: 
Phone: 
+61 7 336 58515
Mobile: 
0400 193 182

Background

Venoms play a range of adaptive roles in the animal kingdom from predation to defense to competitor deterrence. Remarkably, despite their biological importance and uniqueness, the evolution of venom systems is poorly understood. New insights into the evolution of venom systems and the importance of the associated toxins cannot be advanced without recognition of the true biochemical, ecological, morphological and pharmacological diversity of venoms and associated venom systems. A major limitation has been the very narrow taxonomical range studied. Entire groups of venomous animals remain virtually unstudied. My research is inherently interdisciplinary, integrating ecological, evolutionary, and functional genomics approaches in order to understand the evolution of venom systems. Studies range from discovering the shock-inducing hypotensive and anticoagulant venom of the iconic Komodo Dragon through to exploring the unique temperature specific adaptations of Antarctic octopus venoms.

Availability

Professor Bryan Fry is:
Available for supervision
Media expert

Fields of research

Biological Sciences Medicinal and biomolecular chemistry Zoology

Qualifications

  • Doctor of Philosophy, The University of Queensland

Search Professor Bryan Fry’s works on UQ eSpace

224 works between 1998 and 2025
All (224) Journal Article (206) Book Chapter (5) Conference Publication (13)

161 - 180 of 224 works

2015

Journal Article

Privileged frameworks from snake venom

Reeks, T. A., Fry, B. G. and Alewood, P. F. (2015). Privileged frameworks from snake venom. Cellular and Molecular Life Sciences, 72 (10) 1844, 1939-1958. doi: 10.1007/s00018-015-1844-z

Privileged frameworks from snake venom

2015

Journal Article

Production and packaging of a biological arsenal: evolution of centipede venoms under morphological constraint

Undheim, Eivind A.B., Hamilton, Brett R., Kurniawan, Nyoman D., Bowlay, Greg, Cribb, Bronwen W., Merritt, David J., Fry,Bryan G., King, Glenn F and Venter, Deon J. (2015). Production and packaging of a biological arsenal: evolution of centipede venoms under morphological constraint. PNAS: Proceedings of the National Academy of Sciences of the United States of America, 112 (13), 4026-4031. doi: 10.1073/pnas.1424068112

Production and packaging of a biological arsenal: evolution of centipede venoms under morphological constraint

2015

Journal Article

Firing the sting: chemically induced discharge of cnidae reveals novel proteins and peptides from box jellyfish (Chironex fleckeri) venom

Jouiaei, Mahdokht, Casewell, Nicholas R., Yanagihara, Angel A., Nouwens, Amanda, Cribb, Bronwen W., Whitehead, Darryl, Jackson, Timothy N. W., Ali, Syed A., Wagstaff, Simon C., Koludarov, Ivan, Alewood, Paul, Hansen, Jay and Fry, Bryan G. (2015). Firing the sting: chemically induced discharge of cnidae reveals novel proteins and peptides from box jellyfish (Chironex fleckeri) venom. Toxins, 7 (3), 936-950. doi: 10.3390/toxins7030936

Firing the sting: chemically induced discharge of cnidae reveals novel proteins and peptides from box jellyfish (Chironex fleckeri) venom

2015

Journal Article

Centipede venom: Recent discoveries and current state of knowledge

Undheim, Eivind, Fry, Bryan and King, Glenn F (2015). Centipede venom: Recent discoveries and current state of knowledge. Toxins, 7 (3), 679-704. doi: 10.3390/toxins7030679

Centipede venom: Recent discoveries and current state of knowledge

2015

Journal Article

Extreme venom variation in Middle Eastern vipers: A proteomics comparison of Eristicophis macmahonii, Pseudocerastes fieldi and Pseudocerastes persicus

Ali, Syed A., Jackson, Timothy N., Casewell, Nicholas R., Low, Dolyce H.W., Rossi, Sarah, Baumann, Kate, Fathinia, Behzad, Visser, Jeroen, Nouwens, Amanda, Hendrikx, Iwan, Jones, Alun and Fry, Bryan G. (2015). Extreme venom variation in Middle Eastern vipers: A proteomics comparison of Eristicophis macmahonii, Pseudocerastes fieldi and Pseudocerastes persicus. Journal of Proteomics, 116, 106-113. doi: 10.1016/j.jprot.2014.09.003

Extreme venom variation in Middle Eastern vipers: A proteomics comparison of Eristicophis macmahonii, Pseudocerastes fieldi and Pseudocerastes persicus

2015

Book Chapter

Seeing the woods for the trees: understanding venom evolution as a guide for biodiscovery

Fry, Bryan G., Koludarov, Ivan, Jackson, Timothy N. W., Holford, Mandë, Terrat, Yves, Casewell, Nicholas R., Undheim, Eivind A. B., Vetter, Irina, Ali, Syed A., Low, Dolyce H. W. and Sunagar, Kartik (2015). Seeing the woods for the trees: understanding venom evolution as a guide for biodiscovery. Venoms to drugs: venom as a source for the development of human therapeutics. (pp. 1-36) edited by Glenn F. King. Cambridge, United Kingdom: Royal Society of Chemistry. doi: 10.1039/9781849737876-00001

Seeing the woods for the trees: understanding venom evolution as a guide for biodiscovery

2015

Book Chapter

Lesser-known or putative reptile toxins

Fry, Bryan G., Richards, Renee S., Earl, Stephen, Cousin, Xavier, Jackson, Timothy N. W., Weise, Christoph and Sunagar, Kartik (2015). Lesser-known or putative reptile toxins. Venomous reptiles and their toxins: evolution, pathophysiology and biodiscovery. (pp. 364-407) edited by B. G. Fry. New York, NY, United States: Oxford University Press.

Lesser-known or putative reptile toxins

2015

Book Chapter

Research methods

Fry, B. G., Undheim, E. A. B., Jackson, T. N. W., Georgieva, D., Vetter, I., Calvete, J. J., Schieb, H., Cribb, B. W., Yang, D. C., Daly, N. L., Manchadi, M. L. Roy, Gutierrez, J. M., Roelants, K., Lomonte, B., Nicholson, G. M., Dziemborowicz, S., Lavergne, V., Ragnarsson, L., Rash, L. D., Mobli, M., Hodgson, W. C., Casewell, N. R., Nouwens, A., Wagstaff, S. C., Ali, S. A., Whitehead, D. L., Herzig, V., Monagle, P., Kurniawan, N. D. ... Sunagar, K. (2015). Research methods. Venomous reptiles and their toxins: evolution, pathophysiology and biodiscovery. (pp. 153-214) New York, NY, United States: Oxford University Press.

Research methods

2015

Book Chapter

Venoms-Based Drug Discovery: Proteomic and Transcriptomic Approaches

Dutertre, Sebastien, Undheim, Eivind, Pineda, Sandy S., Jin, Ai-Hua (Jean), Lavergne, Vincent, Fry, Bryan G., Lewis, Richard J., Alewood, Paul F. and King, Glenn F. (2015). Venoms-Based Drug Discovery: Proteomic and Transcriptomic Approaches. Venoms to Drugs. (pp. 80-96) edited by King, Glenn F. London, United Kingdom: Royal Society of Chemistry. doi: 10.1039/9781849737876-00080

Venoms-Based Drug Discovery: Proteomic and Transcriptomic Approaches

2014

Journal Article

Fossilized venom: the unusually conserved venom profiles of heloderma species (beaded lizards and gila monsters).

Koludarov, Ivan, Jackson, Timothy N. W., Sunagar, Kartik, Nouwens, Amanda, Hendrikx, Iwan and Fry, Bryan G. (2014). Fossilized venom: the unusually conserved venom profiles of heloderma species (beaded lizards and gila monsters).. Toxins, 6 (12), 3582-3595. doi: 10.3390/toxins6123582

Fossilized venom: the unusually conserved venom profiles of heloderma species (beaded lizards and gila monsters).

2014

Journal Article

Multilocus phylogeography of the sea snake Hydrophis curtus reveals historical vicariance and cryptic lineage diversity

Ukuwela, Kanishka D. B., de Silva, Anslem, Mumpuni, Fry, Bryan G. and Sanders, Kate L. (2014). Multilocus phylogeography of the sea snake Hydrophis curtus reveals historical vicariance and cryptic lineage diversity. Zoologica Scripta, 43 (5), 472-484. doi: 10.1111/zsc.12070

Multilocus phylogeography of the sea snake Hydrophis curtus reveals historical vicariance and cryptic lineage diversity

2014

Journal Article

Clawing through evolution: toxin diversification and convergence in the ancient lineage Chilopoda (Centipedes)

Undheim, Eivind, Jones, Alun, Clauser, Karl R., Holland, John W., Pineda Gonzalez, Sandy, King, Glenn F and Bryan Fry (2014). Clawing through evolution: toxin diversification and convergence in the ancient lineage Chilopoda (Centipedes). Molecular Biology and Evolution, 31 (8), 2124-2148. doi: 10.1093/molbev/msu162

Clawing through evolution: toxin diversification and convergence in the ancient lineage Chilopoda (Centipedes)

2014

Journal Article

A ray of venom: Combined proteomic and transcriptomic investigation of fish venom composition using barb tissue from the blue-spotted stingray (Neotrygon kuhlii)

Baumann, Kate, Casewell, Nicholas R., Ali, Syed A., Jackson, Timothy N. W., Vetter, Irina, Dobson, James S., Cutmore, Scott C., Nouwens, Amanda, Lavergne, Vincent and Fry, Bryan G. (2014). A ray of venom: Combined proteomic and transcriptomic investigation of fish venom composition using barb tissue from the blue-spotted stingray (Neotrygon kuhlii). Journal of Proteomics, 109, 188-198. doi: 10.1016/j.jprot.2014.06.004

A ray of venom: Combined proteomic and transcriptomic investigation of fish venom composition using barb tissue from the blue-spotted stingray (Neotrygon kuhlii)

2014

Journal Article

Multifunctional warheads: diversification of the toxin arsenal of centipedes via novel multidomain transcripts

Undheim, Eivind A. B., Sunagar, Kartik, Hamilton, Brett R., Jones, Alun, Venter, Deon J., Fry, Bryan G. and King, Glenn F. (2014). Multifunctional warheads: diversification of the toxin arsenal of centipedes via novel multidomain transcripts. Journal of Proteomics, 102, 1-10. doi: 10.1016/j.jprot.2014.02.024

Multifunctional warheads: diversification of the toxin arsenal of centipedes via novel multidomain transcripts

2014

Journal Article

Evolution of separate predation- and defence-evoked venoms in carnivorous cone snails

Dutertre, Sébastien, Jin, Ai-Hua, Vetter, Irina, Hamilton, Brett, Sunagar, Kartik, Lavergne, Vincent, Dutertre, Valentin, Fry, Bryan G., Antunes, Agostinho, Venter, Deon J., Alewood, Paul F. and Lewis, Richard J. (2014). Evolution of separate predation- and defence-evoked venoms in carnivorous cone snails. Nature Communications, 5 (3521) 3521, 1-9. doi: 10.1038/ncomms4521

Evolution of separate predation- and defence-evoked venoms in carnivorous cone snails

2014

Journal Article

Intraspecific venom variation in the medically significant Southern Pacific Rattlesnake (Crotalus oreganus helleri): biodiscovery, clinical and evolutionary implications

Sunagar, Kartik, Undheim, Eivind A. B., Scheib, Holger, Gren, Eric C. K., Cochran, Chip, Person, Carl E., Koludarov, Ivan, Kelln, Wayne, Hayes, William K., King, Glenn F., Antunes, Agosthino and Fry, Bryan Grieg (2014). Intraspecific venom variation in the medically significant Southern Pacific Rattlesnake (Crotalus oreganus helleri): biodiscovery, clinical and evolutionary implications. Journal of Proteomics, 99, 68-83. doi: 10.1016/j.jprot.2014.01.013

Intraspecific venom variation in the medically significant Southern Pacific Rattlesnake (Crotalus oreganus helleri): biodiscovery, clinical and evolutionary implications

2014

Journal Article

Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders

Pineda, Sandy S., Sollod, Brianna L., Wilson, David, Darling, Aaron, Sunagar, Kartik, Undheim, Eivind A. B., Kely, Laurence, Antunes, Agostinho, Fry, Bryan G. and King, Glenn F (2014). Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders. BMC Genomics, 15 (1) 177, 177.1-177.16. doi: 10.1186/1471-2164-15-177

Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders

2014

Journal Article

Venomics of new world pit vipers: Genus-wide comparisons of venom proteomes across agkistrodon

Lomonte, Bruno, Tsai, Wan-Chih, Urena-Diaz, Juan Manuel, Sanz, Libia, Mora-Obando, Diana, Sanchez, Elda E., Fry, Bryan G., Gutierrez, Jose Maria, Gibbs, H. Lisle, Sovic, Michael G. and Calvete. Juan J. (2014). Venomics of new world pit vipers: Genus-wide comparisons of venom proteomes across agkistrodon. Journal of Proteomics, 96, 103-116. doi: 10.1016/j.jprot.2013.10.036

Venomics of new world pit vipers: Genus-wide comparisons of venom proteomes across agkistrodon

2014

Journal Article

Vintage venoms: proteomic and pharmacological stability of snake venoms stored for up to eight decades

Jesupret, Clémence, Baumann, Kate, Jackson, Timothy N. W., Ali, Syed Abid, Yang, Daryl C., Greisman, Laura, Kern, Larissa, Steuten, Jessica, Jouiaei, Mahdokht, Casewell, Nicholas R., Undheim, Eivind A. B., Koludarov, Ivan, Debono, Jordan, Low, Dolyce H. W., Rossi, Sarah, Panagides, Nadya, Winter, Kelly, Ignjatovic, Vera, Summerhayes, Robyn, Jones, Alun, Nouwens, Amanda, Dunstan, Nathan, Hodgson, Wayne C., Winkel, Kenneth D., Monagle, Paul and Fry, Bryan Grieg (2014). Vintage venoms: proteomic and pharmacological stability of snake venoms stored for up to eight decades. Journal of Proteomics, 105, 285-294. doi: 10.1016/j.jprot.2014.01.004

Vintage venoms: proteomic and pharmacological stability of snake venoms stored for up to eight decades

2014

Journal Article

Origin and Functional Diversification of an Amphibian Defense Peptide Arsenal

Roelants, Kim, Fry, Bryan G., Ye, Lumeng, Stijlemans, Benoit, Brys, Lea, Kok, Philippe, Clynen, Elke, Schoofs, Liliane, Cornelis, Pierre and Bossuyt, Franky (2014). Origin and Functional Diversification of an Amphibian Defense Peptide Arsenal. Plos Genetics, 9 (8) e1003662, e1003662.1-e1003662.15. doi: 10.1371/journal.pgen.1003662

Origin and Functional Diversification of an Amphibian Defense Peptide Arsenal

Past funding

  • 2021 - 2024
    Evolutionary models and biodiscovery tools from neurotoxic snake venoms
    ARC Discovery Projects
    Open grant
  • 2020 - 2021
    Replacing the use of animals for the study of the alpha-5 subunit of nicotinic acetylcholine receptors and to probe the drug potential of novel ligands for colitis and anti-smoking
    The MAWA Trust
    Open grant
  • 2020 - 2021
    An integrated, multi-node bio-layer interferometry facility
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2019 - 2022
    Functional evolution and therapeutic potential of snake venom coagulotoxins
    ARC Discovery Projects
    Open grant
  • 2019
    Imaging Mass Spectrometry at Higher Mass Resolution
    UQ Research Facilities Infrastructure Grants
    Open grant
  • 2018 - 2019
    Coagulotoxic effects of Brazilian snake venoms: Role in adaptive evolution and human pathophysiological implications
    UQ-FAPESP Strategic Research Fund SPRINT
    Open grant
  • 2018
    Multichannel peptide synthesiser to accelerate UQ's biodiscovery pipeline and peptide drug development programs
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017
    Deep Protein Sequencing, Structure and Quantification Facility
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2016
    Integrative blood coagulation research core facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2016
    Patch-clamp electrophysiology platform for drug and insecticide discovery
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2016
    Evolution of Sea Snakes in Australia's Gulf of Carpentaria
    National Geographic Society
    Open grant
  • 2015
    A sensitive, high resolution QTOF mass spectrometer with nanoUPLC system for qualitative and quantitative biomolecule analysis.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015
    Beyond genomes, transcriptomes and proteomes: high throughput analysis of gene and protein expression and function
    UQ Major Equipment and Infrastructure
    Open grant
  • 2014 - 2017
    Imaging the world of miniature venomous arthropods
    ARC Linkage Projects
    Open grant
  • 2014 - 2016
    Fish venom as a model system for the molecular evolution of defensive toxins
    ARC Discovery Projects
    Open grant
  • 2013 - 2014
    Investigation of the venom of two endangered snakes
    Australian Geographic Pty Limited
    Open grant
  • 2013 - 2014
    ResTeach 2013 0.05 FTE School of Biological Sciences
    UQ ResTeach
    Open grant
  • 2013
    UQ Travel Awards Category 1 - Dr Nicholas Casewell
    UQ Travel Grants Scheme
    Open grant
  • 2011 - 2014
    The only poisonous primates: the ecological and behaviour context of slow loris venom.
    Oxford Brookes University
    Open grant
  • 2011 - 2012
    Molecular toxinology of Australia's lesser known venomous snakes
    ARC Discovery Projects
    Open grant
  • 2011 - 2015
    Adaptive evolution of coleoid (cuttlefish, octopus, squid) venoms
    ARC Future Fellowships
    Open grant
  • 2011
    Evolutionary venomics: Venom system diversification in the animal kingdom
    ARC Discovery Projects
    Open grant

Availability

Professor Bryan Fry is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    Venom variation in American pit vipers

    Principal Advisor

    Other advisors: Dr Andrew Walker

  • Doctor Philosophy

    Evaluation of Phylogenetic Patterns of Scorpion Pathophysiological Effects and Effectiveness of Next-Generation Antivenoms

    Principal Advisor

    Other advisors: Professor Glenn King, Dr Sam Robinson

  • Doctor Philosophy

    Anacondas as sentinel species for accumulation of oil spill heavy metals into the food web

    Principal Advisor

    Other advisors: Professor Jianxin Zhao

  • Doctor Philosophy

    Evolutionary and clinical implications of differential pathophysiological effects of rattlesnake venoms upon blood coagulation, cell function, and nerve transmission.

    Principal Advisor

    Other advisors: Dr Andrew Walker

  • Doctor Philosophy

    Clinical implications and evolutionary insights of Latin American pit viper venom function

    Principal Advisor

    Other advisors: Dr Fernanda Cardoso, Dr Andrew Walker

  • Doctor Philosophy

    Salivary Adaptations in Australian Blood-feeding Arthropods: Insights from Tabanid Flies and the Australian Paralysis Tick

    Associate Advisor

    Other advisors: Professor Glenn King, Dr Andrew Walker

Completed supervision

Enquiries

Contact Professor Bryan Fry directly for media enquiries about:

  • Animal venoms
  • Antivenoms
  • Biodiscovery
  • Drug design
  • Venom

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