Professor Bryan Fry
Professor

Bryan Fry

Email: 
Phone: 
+61 7 336 58515
Mobile: 
0400 193 182

Background

Venoms play a range of adaptive roles in the animal kingdom from predation to defense to competitor deterrence. Remarkably, despite their biological importance and uniqueness, the evolution of venom systems is poorly understood. New insights into the evolution of venom systems and the importance of the associated toxins cannot be advanced without recognition of the true biochemical, ecological, morphological and pharmacological diversity of venoms and associated venom systems. A major limitation has been the very narrow taxonomical range studied. Entire groups of venomous animals remain virtually unstudied. My research is inherently interdisciplinary, integrating ecological, evolutionary, and functional genomics approaches in order to understand the evolution of venom systems. Studies range from discovering the shock-inducing hypotensive and anticoagulant venom of the iconic Komodo Dragon through to exploring the unique temperature specific adaptations of Antarctic octopus venoms.

Availability

Professor Bryan Fry is:
Available for supervision
Media expert

Fields of research

Biological Sciences Medicinal and biomolecular chemistry Zoology

Qualifications

  • Doctor of Philosophy, The University of Queensland

Search Professor Bryan Fry’s works on UQ eSpace

222 works between 1998 and 2025
All (222) Journal Article (204) Book Chapter (5) Conference Publication (13)

101 - 120 of 222 works

2019

Journal Article

Differential destructive (non-clotting) fibrinogenolytic activity in Afro-Asian elapid snake venoms and the links to defensive hooding behavior

Bittenbinder, Mátyás A., Dobson, James S., Zdenek, Christina N., op den Brouw, Bianca, Naude, Arno, Vonk, Freek J. and Fry, Bryan G. (2019). Differential destructive (non-clotting) fibrinogenolytic activity in Afro-Asian elapid snake venoms and the links to defensive hooding behavior. Toxicology in Vitro, 60, 330-335. doi: 10.1016/j.tiv.2019.05.026

Differential destructive (non-clotting) fibrinogenolytic activity in Afro-Asian elapid snake venoms and the links to defensive hooding behavior

2019

Journal Article

Basal but divergent: clinical implications of differential coagulotoxicity in a clade of Asian vipers

Debono, Jordan, Bos, Mettine H.A., Coimbra, Francisco, Ge, Lilin, Frank, Nathaniel, Kwok, Hang Fai and Fry, Bryan G. (2019). Basal but divergent: clinical implications of differential coagulotoxicity in a clade of Asian vipers. Toxicology in Vitro, 58, 195-206. doi: 10.1016/j.tiv.2019.03.038

Basal but divergent: clinical implications of differential coagulotoxicity in a clade of Asian vipers

2019

Journal Article

Coagulotoxic effects by brown snake (Pseudonaja) and taipan (Oxyuranus) venoms, and the efficacy of a new antivenom

Zdenek, Christina N., Hay, Chris, Arbuckle, Kevin, Jackson, Timothy N.W., Bos, Mettine H.A., op den Brouw, Bianca, Debono, Jordan, Allen, Luke, Dunstan, Nathan, Morley, Terry, Herrera, María, Gutiérrez, José M., Williams, David J. and Fry, Bryan G. (2019). Coagulotoxic effects by brown snake (Pseudonaja) and taipan (Oxyuranus) venoms, and the efficacy of a new antivenom. Toxicology in Vitro, 58, 97-109. doi: 10.1016/j.tiv.2019.03.031

Coagulotoxic effects by brown snake (Pseudonaja) and taipan (Oxyuranus) venoms, and the efficacy of a new antivenom

2019

Journal Article

Venomous landmines: Clinical implications of extreme coagulotoxic diversification and differential neutralization by antivenom of venoms within the viperid snake genus Bitis

Youngman, Nicholas J., Debono, Jordan, Dobson, James S., Zdenek, Christina N., Harris, Richard J., op den Brouw, Bianca, Coimbra, Francisco C. P., Naude, Arno, Coster, Kristian, Sundman, Eric, Braun, Ralph, Hendrikx, Iwan and Fry, Bryan G. (2019). Venomous landmines: Clinical implications of extreme coagulotoxic diversification and differential neutralization by antivenom of venoms within the viperid snake genus Bitis. Toxins, 11 (7) 422, 422. doi: 10.3390/toxins11070422

Venomous landmines: Clinical implications of extreme coagulotoxic diversification and differential neutralization by antivenom of venoms within the viperid snake genus Bitis

2019

Journal Article

Varanid lizard venoms disrupt the clotting ability of human fibrinogen through destructive cleavage

Dobson, James S., Zdenek, Christina N., Hay, Chris, Violette, Aude, Fourmy, Rudy, Cochran, Chip and Fry, Bryan G. (2019). Varanid lizard venoms disrupt the clotting ability of human fibrinogen through destructive cleavage. Toxins, 11 (5) 255, 255. doi: 10.3390/toxins11050255

Varanid lizard venoms disrupt the clotting ability of human fibrinogen through destructive cleavage

2019

Journal Article

Habu coagulotoxicity: clinical implications of the functional diversification of Protobothrops snake venoms upon blood clotting factors

Debono, Jordan, Bos, Mettine H.A., Nouwens, Amanda, Ge, Lilin, Frank, Nathaniel, Kwok, Hang Fai and Fry, Bryan (2019). Habu coagulotoxicity: clinical implications of the functional diversification of Protobothrops snake venoms upon blood clotting factors. Toxicology in Vitro, 55, 62-74. doi: 10.1016/j.tiv.2018.11.008

Habu coagulotoxicity: clinical implications of the functional diversification of Protobothrops snake venoms upon blood clotting factors

2019

Conference Publication

Coagulating colubrids: evolutionary, pathophysiological and biodiscovery implications of venom variations between Dispholidus typus and Thelotornis mossambicanus

Debono, Jordan, Dobson, James, Casewell, Nicholas R., Romilio, Anthony, Li, Bin, Kurniawan, Nyoman, Mardon, Karine, Weisbecker, Vera, Nouwens, Amanda, Kwok, Hang Fai and Fry, Bryan G. (2019). Coagulating colubrids: evolutionary, pathophysiological and biodiscovery implications of venom variations between Dispholidus typus and Thelotornis mossambicanus. 19th World Congress of the International-Society-on-Toxinology (IST) / 11th Asia Pacific Congress of the International-Society-on-Toxinology (IST) / 13th Chinese Conference on Toxins and Medical Applications, Haikou, Peoples Republic of China, 24-31 October 2017. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.toxicon.2018.10.144

Coagulating colubrids: evolutionary, pathophysiological and biodiscovery implications of venom variations between Dispholidus typus and Thelotornis mossambicanus

2019

Journal Article

Vampire venom: vasodilatory mechanisms of vampire bat (Desmodus rotundus) blood feeding

Kakumanu, Rahini, Hodgson, Wayne, Ravi, Ravina, Alagon, Alejandro, Harris, Richard, Brust, Andreas, Alewood, Paul, Kemp-Harper, Barbara and Fry, Bryan (2019). Vampire venom: vasodilatory mechanisms of vampire bat (Desmodus rotundus) blood feeding. Toxins, 11 (1) 26, 26. doi: 10.3390/toxins11010026

Vampire venom: vasodilatory mechanisms of vampire bat (Desmodus rotundus) blood feeding

2019

Journal Article

Mud in the blood: Novel potent anticoagulant coagulotoxicity in the venoms of the Australian elapid snake genus Denisonia (mud adders) and relative antivenom efficacy

Youngman, Nicholas J., Zdenek, Christina N., Dobson, James S., Bittenbinder, Matyas A., Gillett, Amber, Hamilton, Brett, Dunstan, Nathan, Allen, Luke, Veary, Andrew, Veary, Elle and Fry, Bryan G. (2019). Mud in the blood: Novel potent anticoagulant coagulotoxicity in the venoms of the Australian elapid snake genus Denisonia (mud adders) and relative antivenom efficacy. Toxicology Letters, 302, 1-6. doi: 10.1016/j.toxlet.2018.11.015

Mud in the blood: Novel potent anticoagulant coagulotoxicity in the venoms of the Australian elapid snake genus Denisonia (mud adders) and relative antivenom efficacy

2018

Journal Article

Coagulotoxic Cobras: Clinical Implications of Strong Anticoagulant Actions of African Spitting Naja Venoms That Are Not Neutralised by Antivenom but Are by LY315920 (Varespladib)

Bittenbinder, Mátyás A., Zdenek, Christina N., op den Brouw, Bianca, Youngman, Nicholas J., Dobson, James S., Naude, Arno, Vonk, Freek J. and Fry, Bryan G. (2018). Coagulotoxic Cobras: Clinical Implications of Strong Anticoagulant Actions of African Spitting Naja Venoms That Are Not Neutralised by Antivenom but Are by LY315920 (Varespladib). Toxins, 10 (12) 516, 516. doi: 10.3390/toxins10120516

Coagulotoxic Cobras: Clinical Implications of Strong Anticoagulant Actions of African Spitting Naja Venoms That Are Not Neutralised by Antivenom but Are by LY315920 (Varespladib)

2018

Journal Article

Future directions in the research and management of marine snakes

Udyawer, Vinay, Barnes, Peter, Bonnet, Xavier, Brischoux, François, Crowe-Riddell, Jenna M., D'Anastasi, Blanche, Fry, Bryan G., Gillett, Amber, Goiran, Claire, Guinea, Michael L., Heatwole, Harold, Heupel, Michelle R., Hourston, Mathew, Kangas, Mervi, Kendrick, Alan, Koefoed, Inigo, Lillywhite, Harvey B., Lobo, Aaron S., Lukoschek, Vimoksalehi, McAuley, Rory, Nitschke, Charlotte, Rasmussen, Arne R., Sanders, Kate L., Sheehy, Coleman, Shine, Richard, Somaweera, Ruchira, Sweet, Samuel S. and Voris, Harold K. (2018). Future directions in the research and management of marine snakes. Frontiers in Marine Science, 9 (NOV) 399. doi: 10.3389/fmars.2018.00399

Future directions in the research and management of marine snakes

2018

Journal Article

Buzz kill: Function and proteomic composition of venom from the Giant Assassin Fly Dolopus genitalis (Diptera: Asilidae)

Walker, Andrew, Dobson, James, Jin, Jiayi, Robinson, Samuel, Herzig, Volker, Vetter, Irina, King, Glenn and Fry, Bryan (2018). Buzz kill: Function and proteomic composition of venom from the Giant Assassin Fly Dolopus genitalis (Diptera: Asilidae). Toxins, 10 (11) 456, 456. doi: 10.3390/toxins10110456

Buzz kill: Function and proteomic composition of venom from the Giant Assassin Fly Dolopus genitalis (Diptera: Asilidae)

2018

Journal Article

Coagulotoxicity of Bothrops (Lancehead Pit-Vipers) venoms from Brazil: differential biochemistry and antivenom efficacy resulting from prey-driven venom variation

Sousa, Leijiane F., Zdenek, Christina N., Dobson, James S., Op den Brouw, Bianca, Coimbra, Francisco, Gillett, Amber, Del-Rei, Tiago H M, Chalkidis, Hipócrates de M, Sant'Anna, Sávio, Teixeira-da-Rocha, Marisa M., Grego, Kathleen, Travaglia Cardoso, Silvia R., Moura da Silva, Ana M. and Fry, Bryan G. (2018). Coagulotoxicity of Bothrops (Lancehead Pit-Vipers) venoms from Brazil: differential biochemistry and antivenom efficacy resulting from prey-driven venom variation. Toxins, 10 (10) 411, 411. doi: 10.3390/toxins10100411

Coagulotoxicity of Bothrops (Lancehead Pit-Vipers) venoms from Brazil: differential biochemistry and antivenom efficacy resulting from prey-driven venom variation

2018

Journal Article

Entomo-venomics: the evolution, biology and biochemistry of insect venoms

Walker, Andrew A., Robinson, Samuel D., Yeates, David K., Jin, Jiayi, Baumann, Kate, Dobson, James, Fry, Bryan G. and King, Glenn F. (2018). Entomo-venomics: the evolution, biology and biochemistry of insect venoms. Toxicon: official journal of the International Society on Toxinology, 154, 15-27. doi: 10.1016/j.toxicon.2018.09.004

Entomo-venomics: the evolution, biology and biochemistry of insect venoms

2018

Journal Article

Does size matter? Venom proteomic and functional comparison between night adder species (Viperidae: Causus) with short and long venom glands

Coimbra, Francisco C. P., Dobson, James, Zdenek, Christina N., Op den Brouw, Bianca, Hamilton, Brett, Debono, Jordan, Masci, Paul, Frank, Nathaniel, Ge, Lilin, Kwok, Hang Fai and Fry, Bryan G. (2018). Does size matter? Venom proteomic and functional comparison between night adder species (Viperidae: Causus) with short and long venom glands. Comparative Biochemistry and Physiology. Part C: Toxicology & Pharmacology, 211, 7-14. doi: 10.1016/j.cbpc.2018.05.003

Does size matter? Venom proteomic and functional comparison between night adder species (Viperidae: Causus) with short and long venom glands

2018

Journal Article

Erratum: A new species of bandy-bandy (Vermicella: Serpentes: Elapidae) from the Weipa region, Cape York, Australia(Zootaxa (2018) 4446 (001–012) DOI: 10.11646/zootaxa.4446.1.1)

Derez, Chantelle M, Arbuckle, Kevin, Ruan, Zhiqiang, Xie, Bing, Huang, Yu, Dibben, Lauren, Shi, Qiong, Vonk, Freek J and Fry, Bryan G (2018). Erratum: A new species of bandy-bandy (Vermicella: Serpentes: Elapidae) from the Weipa region, Cape York, Australia(Zootaxa (2018) 4446 (001–012) DOI: 10.11646/zootaxa.4446.1.1). Zootaxa, 4461 (4), 600-600. doi: 10.11646/zootaxa.4461.4.9

Erratum: A new species of bandy-bandy (Vermicella: Serpentes: Elapidae) from the Weipa region, Cape York, Australia(Zootaxa (2018) 4446 (001–012) DOI: 10.11646/zootaxa.4446.1.1)

2018

Journal Article

Scratching the surface of an itch: molecular evolution of Aculeata venom allergens

Baumann, Kate, Dashevsky, Daniel, Sunagar, Kartik and Fry, Bryan (2018). Scratching the surface of an itch: molecular evolution of Aculeata venom allergens. Journal of Molecular Evolution, 86 (7), 484-500. doi: 10.1007/s00239-018-9860-x

Scratching the surface of an itch: molecular evolution of Aculeata venom allergens

2018

Journal Article

A new species of bandy-bandy (Vermicella: Serpentes: Elapidae) from the Weipa region, Cape York, Australia

Derez, Chantelle M., Arbuckle, Kevin, Ruan, Zhiqiang, Xie, Bing, Huang, Yu, Dibben, Lauren, Shi, Qiong, Vonik, Freek J. and Fry, Bryan G. (2018). A new species of bandy-bandy (Vermicella: Serpentes: Elapidae) from the Weipa region, Cape York, Australia. Zootaxa, 4446 (1), 1-12. doi: 10.11646/zootaxa.4446.1.1

A new species of bandy-bandy (Vermicella: Serpentes: Elapidae) from the Weipa region, Cape York, Australia

2018

Journal Article

Correction to: Harden up: metal acquisition in the weaponized ovipositors of aculeate hymenoptera

Baumann, Kate, Vicenzi, Edward P., Lam, Thomas, Douglas, Janet, Arbuckle, Kevin, Cribb, Bronwen, Brady, Seán G. and Fry, Bryan G. (2018). Correction to: Harden up: metal acquisition in the weaponized ovipositors of aculeate hymenoptera. Zoomorphology, 137 (3), 407-408. doi: 10.1007/s00435-018-0413-z

Correction to: Harden up: metal acquisition in the weaponized ovipositors of aculeate hymenoptera

2018

Journal Article

Factor X activating atractaspis snake venoms and the relative coagulotoxicity neutralising efficacy of African antivenoms

Oulion, Brice, Dobson, James S., Zdenek, Christina N., Arbuckle, Kevin, Lister, Callum, Coimbra, Francisco C. P., Op den Brouw, Bianca, Debono, Jordan, Rogalski, Aymeric, Violette, Aude, Fourmy, Rudy, Frank, Nathaniel and Fry, Bryan G. (2018). Factor X activating atractaspis snake venoms and the relative coagulotoxicity neutralising efficacy of African antivenoms. Toxicology Letters, 288, 119-128. doi: 10.1016/j.toxlet.2018.02.020

Factor X activating atractaspis snake venoms and the relative coagulotoxicity neutralising efficacy of African antivenoms

Past funding

  • 2021 - 2024
    Evolutionary models and biodiscovery tools from neurotoxic snake venoms
    ARC Discovery Projects
    Open grant
  • 2020 - 2021
    Replacing the use of animals for the study of the alpha-5 subunit of nicotinic acetylcholine receptors and to probe the drug potential of novel ligands for colitis and anti-smoking
    The MAWA Trust
    Open grant
  • 2020 - 2021
    An integrated, multi-node bio-layer interferometry facility
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2019 - 2022
    Functional evolution and therapeutic potential of snake venom coagulotoxins
    ARC Discovery Projects
    Open grant
  • 2019
    Imaging Mass Spectrometry at Higher Mass Resolution
    UQ Research Facilities Infrastructure Grants
    Open grant
  • 2018 - 2019
    Coagulotoxic effects of Brazilian snake venoms: Role in adaptive evolution and human pathophysiological implications
    UQ-FAPESP Strategic Research Fund SPRINT
    Open grant
  • 2018
    Multichannel peptide synthesiser to accelerate UQ's biodiscovery pipeline and peptide drug development programs
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017
    Deep Protein Sequencing, Structure and Quantification Facility
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2016
    Integrative blood coagulation research core facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2016
    Patch-clamp electrophysiology platform for drug and insecticide discovery
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2016
    Evolution of Sea Snakes in Australia's Gulf of Carpentaria
    National Geographic Society
    Open grant
  • 2015
    A sensitive, high resolution QTOF mass spectrometer with nanoUPLC system for qualitative and quantitative biomolecule analysis.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015
    Beyond genomes, transcriptomes and proteomes: high throughput analysis of gene and protein expression and function
    UQ Major Equipment and Infrastructure
    Open grant
  • 2014 - 2017
    Imaging the world of miniature venomous arthropods
    ARC Linkage Projects
    Open grant
  • 2014 - 2016
    Fish venom as a model system for the molecular evolution of defensive toxins
    ARC Discovery Projects
    Open grant
  • 2013 - 2014
    Investigation of the venom of two endangered snakes
    Australian Geographic Pty Limited
    Open grant
  • 2013 - 2014
    ResTeach 2013 0.05 FTE School of Biological Sciences
    UQ ResTeach
    Open grant
  • 2013
    UQ Travel Awards Category 1 - Dr Nicholas Casewell
    UQ Travel Grants Scheme
    Open grant
  • 2011 - 2014
    The only poisonous primates: the ecological and behaviour context of slow loris venom.
    Oxford Brookes University
    Open grant
  • 2011 - 2012
    Molecular toxinology of Australia's lesser known venomous snakes
    ARC Discovery Projects
    Open grant
  • 2011 - 2015
    Adaptive evolution of coleoid (cuttlefish, octopus, squid) venoms
    ARC Future Fellowships
    Open grant
  • 2011
    Evolutionary venomics: Venom system diversification in the animal kingdom
    ARC Discovery Projects
    Open grant

Availability

Professor Bryan Fry is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    Clinical implications and evolutionary insights of Latin American pit viper venom function

    Principal Advisor

    Other advisors: Dr Fernanda Cardoso, Dr Andrew Walker

  • Doctor Philosophy

    Evaluation of Phylogenetic Patterns of Scorpion Pathophysiological Effects and Effectiveness of Next-Generation Antivenoms

    Principal Advisor

    Other advisors: Professor Glenn King, Dr Sam Robinson

  • Doctor Philosophy

    The evolution of prey-selectivity for snake venom neurotoxins, and the parallel evolution of neurotoxin resistance in prey

    Principal Advisor

  • Doctor Philosophy

    Pathophysiological actions of elapid snake venom on prey and human targets

    Principal Advisor

  • Doctor Philosophy

    Venom variation in New World pit vipers

    Principal Advisor

    Other advisors: Dr Fernanda Cardoso, Dr Andrew Walker

  • Doctor Philosophy

    Pathophysiological actions of elapid snake venom on prey and human targets

    Principal Advisor

  • Doctor Philosophy

    Evaluation of Phylogenetic Patterns of Scorpion Pathophysiological Effects and Effectiveness of Next-Generation Antivenoms

    Principal Advisor

    Other advisors: Professor Glenn King, Dr Sam Robinson

  • Doctor Philosophy

    Venom variation in American pit vipers

    Principal Advisor

    Other advisors: Dr Andrew Walker

  • Doctor Philosophy

    Anacondas as sentinel species for accumulation of oil spill heavy metals into the food web

    Principal Advisor

    Other advisors: Professor Jianxin Zhao

  • Doctor Philosophy

    Evolutionary and clinical implications of differential pathophysiological effects of rattlesnake venoms upon blood coagulation, cell function, and nerve transmission.

    Principal Advisor

    Other advisors: Dr Andrew Walker

  • Doctor Philosophy

    Clinical implications and evolutionary insights of Latin American pit viper venom function

    Principal Advisor

    Other advisors: Dr Fernanda Cardoso, Dr Andrew Walker

  • Doctor Philosophy

    Pathophysiological actions of elapid venom on prey and human targets

    Principal Advisor

  • Doctor Philosophy

    Utilising invertebrates to identify novel coagulotoxins

    Associate Advisor

    Other advisors: Professor Glenn King, Dr Andrew Walker

Completed supervision

Enquiries

Contact Professor Bryan Fry directly for media enquiries about:

  • Animal venoms
  • Antivenoms
  • Biodiscovery
  • Drug design
  • Venom

Need help?

For help with finding experts, story ideas and media enquiries, contact our Media team:

communications@uq.edu.au