![Dr Nyoman Kurniawan](/sites/default/files/profiles/811.jpeg)
Overview
Background
Dr Nyoman Kurniawan is a Senior Research Fellow in the Centre for Advanced Imaging and the Facility Manager for Preclincal 16.4T Microimaging 9.4T MRI scanners.
Dr Kurniawan’s research areas are:
- Diffusion magnetic resonance imaging of mouse neuroanatomy, with view to study neurological disease model, including:
- developmental abnormalities
- spinal cord diseases
- Development of 3D mouse brain, human spinal cord and cephalopod brain atlases using high resolution structural and diffusion MRI
- Development of MR methods for nephron imaging
- Application of MRI for agriculture imaging
Availability
- Dr Nyoman Kurniawan is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Science, The University of Queensland
- Bachelor (Honours) of Science (Advanced), The University of Queensland
- Doctor of Philosophy, The University of Queensland
Research interests
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Spinal cord MRI
Using MRI to study degeneration and recovery in animal models of MS (EAE) and translation to clinical settings.
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Kidney imaging
Development of new MRI methods to image nephrons
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Development of structural connectome for animal model
Using diffusion MRI and fibre tracking to analyse brain wiring in animal models (rodents, fish, chepalopods)
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Development of MRI methods for agriculture imaging
Using MRI to characterise fruit maturation/ripening and root responses in crops.
Research impacts
Dr Kurniawan research focus is development of new MRI approaches for characterising animal models and ex vivo tissue specimens with the aim of relating the MRI signal to underlying tissue microstructures and processes. Insights gained with this approach have the potential to translate into improved use of MRI in humans. For example, he is working with clinicians at the Jamieson Trauma Institute to develop diffusion methods to measure brachial plexus injury.
Dr Kurniawan has a number of national and international collaborations, in the area of tumour microimaging (University of Sydney); multimodal MR imaging of Alzheimer brain (University of Southern California, USA), developing human spinal cord atlas (Polytechnique Montreal, Canada), and nephron imaging (Monash and University of Nottingham, UK).
Dr Kurniawan also works tangentialy in the applications of MRI to characterise agricultural products. He has been working with Uniquely Australian Foods at QAFFI, using MRI to characterise native fruit maturation and ripening process for commercialisation. Recently, he has obtained research infrastructure funding to establish Agriculture MRI facility at the Gatton Campus.
Works
Search Professor Nyoman Kurniawan’s works on UQ eSpace
2018
Journal Article
A pan-mammalian map of interhemispheric brain connections predates the evolution of the corpus callosum
Suárez, Rodrigo, Paolino, Annalisa, Fenlon, Laura R., Morcom, Laura R., Kozulin, Peter, Kurniawan, Nyoman D. and Richards, Linda J. (2018). A pan-mammalian map of interhemispheric brain connections predates the evolution of the corpus callosum. Proceedings of the National Academy of Sciences, 115 (38), 9622-9627. doi: 10.1073/pnas.1808262115
2018
Journal Article
Novel theranostic nanoplatform for complete mice tumor elimination via MR imaging-guided acid-enhanced photothermo-/chemo-therapy
Li, Bei, Tang, Jie, Chen, Weiyu, Hao, Guanyu, Kurniawan, Nyoman, Gu, Zi and Xu, Zhi Ping (2018). Novel theranostic nanoplatform for complete mice tumor elimination via MR imaging-guided acid-enhanced photothermo-/chemo-therapy. Biomaterials, 177, 40-51. doi: 10.1016/j.biomaterials.2018.05.055
2018
Journal Article
Hexarelin treatment preserves myocardial function and reduces cardiac fibrosis in a mouse model of acute myocardial infarction
McDonald, Hayley, Peart, Jason, Kurniawan, Nyoman, Galloway, Graham, Royce, Simon, Samuel, Chrishan S. and Chen, Chen (2018). Hexarelin treatment preserves myocardial function and reduces cardiac fibrosis in a mouse model of acute myocardial infarction. Physiological Reports, 6 (9) e13699, e13699. doi: 10.14814/phy2.13699
2018
Journal Article
Early gestational ethanol exposure in mice: effects on brain structure, energy metabolism and adiposity in adult offspring
Zhang, Christine R., Kurniawan, Nyoman D., Yamada, Lisa, Fleming, Whitney, Kaminen-Ahola, Nina, Ahola, Arttu, Galloway, Graham and Chong, Suyinn (2018). Early gestational ethanol exposure in mice: effects on brain structure, energy metabolism and adiposity in adult offspring. Alcohol, 75, 1-10. doi: 10.1016/j.alcohol.2018.04.008
2018
Journal Article
Utility of gradient recalled echo magnetic resonance imaging for the study of myelination in cuprizone mice treated with fingolimod
Ziser, Laura, Meyer-Schell, Naja, Kurniawan, Nyoman D, Sullivan, Robert, Reutens, David, Chen, Min and Vegh, Viktor (2018). Utility of gradient recalled echo magnetic resonance imaging for the study of myelination in cuprizone mice treated with fingolimod. NMR in Biomedicine, 31 (3) e3877, e3877. doi: 10.1002/nbm.3877
2018
Journal Article
A combined tract-based spatial statistics and voxel-based morphometry study of the first MRI scan after diagnosis of amyotrophic lateral sclerosis with subgroup analysis
Alruwaili, A. R., Pannek, K., Coulthard, A., Henderson, R., Kurniawan, N. D. and McCombe, P. (2018). A combined tract-based spatial statistics and voxel-based morphometry study of the first MRI scan after diagnosis of amyotrophic lateral sclerosis with subgroup analysis. Journal of Neuroradiology, 45 (1), 41-48. doi: 10.1016/j.neurad.2017.03.007
2018
Journal Article
MRI in the study of animal models of neurodegenerative diseases
Kurniawan, Nyoman D. (2018). MRI in the study of animal models of neurodegenerative diseases. Methods in Molecular Biology , 1718, 347-375. doi: 10.1007/978-1-4939-7531-0_21
2018
Journal Article
Vitamin D deficiency is associated with reduced hippocampal volume and disrupted structural connectivity in patients with mild cognitive impairment
Al-Amin, Mamun, Bradford, DanaKai, Sullivan, Robert K. P., Kurniawan, Nyoman D., Moon, Yeonsil, Han, Seol-Heui, Zalesky, Andrew and Burne, Thomas H. J. (2018). Vitamin D deficiency is associated with reduced hippocampal volume and disrupted structural connectivity in patients with mild cognitive impairment. Human Brain Mapping, 40 (2), 394-406. doi: 10.1002/hbm.24380
2017
Journal Article
Radiological studies of fetal alcohol spectrum disorders in humans and animal models: an updated comprehensive review
Nguyen, Van T., Chong, Suyinn, Tieng, Quang M., Mardon, Karine, Galloway, Graham J. and Kurniawan, Nyoman D. (2017). Radiological studies of fetal alcohol spectrum disorders in humans and animal models: an updated comprehensive review. Magnetic Resonance Imaging, 43, 10-26. doi: 10.1016/j.mri.2017.06.012
2017
Journal Article
[OP.3B.05] Hexarelin preserves myocardial function and reduces inflammation and fibrosis in a mouse model of myocardial ischemia reperfusion
Mcdonald, H., Peart, J., Kurniawan, N.D., Galloway, G., Royce, S.G., Samuel, C.S. and Chen, C. (2017). [OP.3B.05] Hexarelin preserves myocardial function and reduces inflammation and fibrosis in a mouse model of myocardial ischemia reperfusion. Journal of Hypertension, 35 (Supplement 2), e29-e29. doi: 10.1097/01.hjh.0000523053.36429.97
2017
Journal Article
Manganese-based layered double hydroxide nanoparticles as a T1-MRI contrast agent with ultrasensitive pH response and high relaxivity
Li, Bei, Gu, Zi, Kurniawan, Nyoman, Chen, Weiyu and Xu, Zhi Ping (2017). Manganese-based layered double hydroxide nanoparticles as a T1-MRI contrast agent with ultrasensitive pH response and high relaxivity. Advanced Materials, 29 (29) 1700373, 1700373. doi: 10.1002/adma.201700373
2017
Journal Article
Complement C5aR1 signaling promotes polarization and proliferation of embryonic neural progenitor cells through PKCζ
Coulthard, Liam G., Hawksworth, Owen A., Li, Rui, Balachandran, Anushree, Lee, John D., Sepehrband, Farshid, Kurniawan, Nyoman, Jeanes, Angela, Simmons, David G., Wolvetang, Ernst and Woodruff, Trent M. (2017). Complement C5aR1 signaling promotes polarization and proliferation of embryonic neural progenitor cells through PKCζ. Journal of Neuroscience, 37 (22), 5395-5407. doi: 10.1523/JNEUROSCI.0525-17.2017
2017
Journal Article
Coagulating colubrids: evolutionary, pathophysiological and biodiscovery implications of venom variations between boomslang (Dispholidus typus) and twig snake (Thelotornis mossambicanus)
Debono, Jordan, Dobson, James, Casewell, Nicholas R., Romilio, Anthony, Li, Bin, Kurniawan, Nyoman, Mardon, Karine, Weisbecker, Vera, Nouwens, Amanda , Kwok, Hang Fai and Fry, Bryan G. (2017). Coagulating colubrids: evolutionary, pathophysiological and biodiscovery implications of venom variations between boomslang (Dispholidus typus) and twig snake (Thelotornis mossambicanus). Toxins, 9 (5) 171, 171. doi: 10.3390/toxins9050171
2017
Conference Publication
Complement anaphylatoxin receptors have critical physiological functions in the developing mammalian brain
Woodruff, Trent M., Hawksworth, Owen A., Li, Rui, Balachandran, Anushree, Leel, John D., Sepehrband', Farshid, Kurniawan, Nyoman, Jeanes, Angela, Simmons, David G., Wolvetang, Ernst and Coulthard, Liam G. (2017). Complement anaphylatoxin receptors have critical physiological functions in the developing mammalian brain. 16th European Meeting on Complement in Human Disease (EMCHD), Copenhagen Denmark, 8-12 September 2017. Kidlington, Oxford United Kingdom: Pergamon Press. doi: 10.1016/j.molimm.2017.06.178
2016
Journal Article
Altered structural connectome in adolescent socially isolated mice
Liu, Cirong, Li, Yonghui, Edwards, Timothy J., Kurniawan, Nyoman D., Richards, Linda J. and Jiang, Tianzi (2016). Altered structural connectome in adolescent socially isolated mice. NeuroImage, 139, 259-270. doi: 10.1016/j.neuroimage.2016.06.037
2016
Journal Article
Risperidone induces long-lasting changes in the conditioned avoidance response and accumbal gene expression selectively in animals treated as adolescents
Moe, Aung Aung Kywe, Kurniawan, Nyoman D., Alexander, Suzanne, Cui, Xiaoying, Burne, Thomas H. J. and Eyles, Darryl W. (2016). Risperidone induces long-lasting changes in the conditioned avoidance response and accumbal gene expression selectively in animals treated as adolescents. Neuropharmacology, 108, 264-274. doi: 10.1016/j.neuropharm.2016.04.035
2016
Journal Article
IVIg attenuates complement and improves spinal cord injury outcomes in mice
Brennan, Faith H., Kurniawan, Nyoman D., Vukovic, Jana, Bartlett, Perry F., Käsermann, Fabian, Arumugam, Thiruman V., Basta, Milan and Ruitenberg, Marc J. (2016). IVIg attenuates complement and improves spinal cord injury outcomes in mice. Annals of Clinical and Translational Neurology, 3 (7), 495-511. doi: 10.1002/acn3.318
2016
Journal Article
Parametric probability distribution functions for axon diameters of corpus callosum
Sepehrband, Farshid, Alexander, Daniel C., Clark, Kristi A., Kurniawan, Nyoman D., Yang, Zhengyi and Reutens, David C. (2016). Parametric probability distribution functions for axon diameters of corpus callosum. Frontiers in Neuroanatomy, 10 (MAY) 59, 59. doi: 10.3389/fnana.2016.00059
2016
Journal Article
Towards higher sensitivity and stability of axon diameter estimation with diffusion-weighted MRI
Sepehrband, Farshid, Alexander, Daniel C., Kurniawan, Nyoman D., Reutens, David C. and Yang, Zhengyi (2016). Towards higher sensitivity and stability of axon diameter estimation with diffusion-weighted MRI. NMR in Biomedicine, 29 (3), 293-308. doi: 10.1002/nbm.3462
2016
Conference Publication
Cardioprotective Role of Hexarelin in a Mouse Model of Myocardial Infarction
McDonald, Hayley, Peart, Jason, Kurniawan, Nyoman, Galloway, Graham, Samuel, Chrishan and Chen, Chen (2016). Cardioprotective Role of Hexarelin in a Mouse Model of Myocardial Infarction. Annual Conference of the British-Cardiovascular-Society (BCS) on Prediction and Prevention, Manchester, England, United Kingdom, Jun 06-08, 2016. London, United Kingdom: B M J Group. doi: 10.1136/heartjnl-2016-309890.184
Funding
Current funding
Supervision
Availability
- Dr Nyoman Kurniawan is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
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Developing novel methods of kidney MRI acquisition and image analysis using artificial intelligence
Nephrons are the basic functional unit of the kidney, an organ with a central role in maintaining homeostasis in the body. The number of nephrons in the kidneys and their microstructure reflect the success of renal development and the trajectory of renal health through life. Low nephron number increases the risk of chronic kidney disease, hypertension and cardiovascular disease.
Current methods for nephron quantitation are limited to ex vivo methods which are labour intensive, affected by shrinkage or use contrast agents. Magnetic Resonance Imaging (MRI) has strong potential to characterise kidney microstructures, but in vivo it suffers from low image resolution and motion artefacts. This PhD project aims to develop novel methods for kidney MR image acquisitions and analyses using artificial intelligence (such as Deep Learning and super resolution methods) to allow characterisation of key components of nephrons, the glomeruli and tubules. It is expected that these new methods will play important roles in future kidney research and contribute to reducing Australia’s epidemic of chronic kidney disease.
This is an opportunity to work with researchers at the Centre for Advanced Imaging, a leading imaging research facility in Australia, and The University of Queensland School of Information Technology and Electrical Engineering.
The project will suit an enthusiastic and highly motivated student with a background in computer science, physics or engineering.
Supervision history
Current supervision
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Doctor Philosophy
Mapping human cervical spinal cord using high resolution structural and diffusion magnetic resonance imaging
Principal Advisor
Other advisors: Dr Gary Cowin
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Doctor Philosophy
Machine learning methods for visualisation and quantification of nephrons with MRI.
Associate Advisor
Other advisors: Dr Shakes Chandra
Completed supervision
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2024
Doctor Philosophy
Development of Diffusion MRI and Tractography Protocols to Characterise Mouse Brain Development
Principal Advisor
Other advisors: Professor Michael Piper
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2023
Doctor Philosophy
Multimodal MRI to monitor disease and treatment in a chronic-progressive EAE mouse model of multiple sclerosis
Principal Advisor
Other advisors: Dr Gary Cowin, Dr Nemat Khan
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2019
Doctor Philosophy
Advanced Diffusion Magnetic Resonance Imaging at Ultrahigh Field to Investigate Neurological Microstructural Changes in an EAE Mouse Model of Multiple Sclerosis
Principal Advisor
Other advisors: Emeritus Professor Maree Smith
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2018
Doctor Philosophy
Anatomical Study of the Human Cervical Spinal Cord and Pathology Assessment of Spinal Cord Injury in Animal Models Using Magnetic Resonance Imaging
Principal Advisor
Other advisors: Dr Gary Cowin, Professor Marc Ruitenberg
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2018
Doctor Philosophy
Neurological study of a mouse model of Fetal Alcohol Spectrum Disorders using advanced imaging techniques
Principal Advisor
Other advisors: Professor Graham Galloway, Dr Karine Mardon
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2015
Doctor Philosophy
Development of magnetic resonance diffusion weighted imaging at 16.4T to assess neurological degeneration in a mouse model of multiple sclerosis
Principal Advisor
Other advisors: Emeritus Professor Maree Smith, Professor Graham Galloway
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2020
Doctor Philosophy
The cardioprotective effects of growth hormone secretagogues in mouse models of myocardial ischemia reperfusion and infarction
Associate Advisor
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2017
Doctor Philosophy
Measuring the progression of upper motor neuron disease using diffusion MRI and its correlation with Clinical phenotype
Associate Advisor
Other advisors: Associate Professor Robert Henderson, Professor Pamela McCombe, Dr Kerstin Pannek
Media
Enquiries
Contact Dr Nyoman Kurniawan directly for media enquiries about:
- Imaging - MRI
- Magnetic Resonance Imaging
- MRI
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