
Overview
Background
Dr Nyoman Kurniawan is a Senior Research Fellow in the Centre for Advanced Imaging and the Facility Manager for Preclincal 16.4T Microimaging 9.4T MRI scanners.
Dr Kurniawan’s research areas are:
- Diffusion magnetic resonance imaging of mouse neuroanatomy, with view to study neurological disease model, including:
- developmental abnormalities
- spinal cord diseases
- Development of 3D mouse brain, human spinal cord and cephalopod brain atlases using high resolution structural and diffusion MRI
- Development of MR methods for nephron imaging
- Application of MRI for agriculture imaging
Availability
- Dr Nyoman Kurniawan is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Science, The University of Queensland
- Bachelor (Honours) of Science (Advanced), The University of Queensland
- Doctor of Philosophy, The University of Queensland
Research interests
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Spinal cord MRI
Using MRI to study degeneration and recovery in animal models of MS (EAE) and translation to clinical settings.
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Kidney imaging
Development of new MRI methods to image nephrons
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Development of structural connectome for animal model
Using diffusion MRI and fibre tracking to analyse brain wiring in animal models (rodents, fish, chepalopods)
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Development of MRI methods for agriculture imaging
Using MRI to characterise fruit maturation/ripening and root responses in crops.
Research impacts
Dr Kurniawan research focus is development of new MRI approaches for characterising animal models and ex vivo tissue specimens with the aim of relating the MRI signal to underlying tissue microstructures and processes. Insights gained with this approach have the potential to translate into improved use of MRI in humans. For example, he is working with clinicians at the Jamieson Trauma Institute to develop diffusion methods to measure brachial plexus injury.
Dr Kurniawan has a number of national and international collaborations, in the area of tumour microimaging (University of Sydney); multimodal MR imaging of Alzheimer brain (University of Southern California, USA), developing human spinal cord atlas (Polytechnique Montreal, Canada), and nephron imaging (Monash and University of Nottingham, UK).
Dr Kurniawan also works tangentialy in the applications of MRI to characterise agricultural products. He has been working with Uniquely Australian Foods at QAFFI, using MRI to characterise native fruit maturation and ripening process for commercialisation. Recently, he has obtained research infrastructure funding to establish Agriculture MRI facility at the Gatton Campus.
Works
Search Professor Nyoman Kurniawan’s works on UQ eSpace
2013
Journal Article
A proteomics and transcriptomics investigation of the venom from the Barychelid spider Trittame loki (brush-foot trapdoor)
Undheim, Eivind A. B., Sunagar, Kartik, Herzig, Volker, Kely, Laurence, Low, Dolyce H. W., Jackson, Timothy N. W., Jones, Alun, Kurniawan, Nyoman, King, Glenn F., Ali, Syed A., Antunes, Agostino, Ruder, Tim and Fry, Bryan G. (2013). A proteomics and transcriptomics investigation of the venom from the Barychelid spider Trittame loki (brush-foot trapdoor). Toxins, 5 (12), 2488-2503. doi: 10.3390/toxins5122488
2013
Journal Article
Detection of endogenous iron deposits in the injured mouse spinal cord through high-resolution ex vivo and in vivo MRI
Blomster, Linda V., Cowin, Gary J., Kurniawan, Nyoman D. and Ruitenberg, Marc J. (2013). Detection of endogenous iron deposits in the injured mouse spinal cord through high-resolution ex vivo and in vivo MRI. NMR in Biomedicine, 26 (2), 141-150. doi: 10.1002/nbm.2829
2013
Other Outputs
Average wild-type C57BL/6J mouse 3D MRI hippocampus labels
Janke, Andrew, Kurniawan, Nyoman D., Ullmann, Jeremy F., Reutens, David, Galloway, Graham J. and Watson, Charles (2013). Average wild-type C57BL/6J mouse 3D MRI hippocampus labels. The University of Queensland. (Dataset) doi: 10.14264/uql.2015.868
2012
Journal Article
MRI-guided volume reconstruction of mouse brain from histological sections
Yang, Zhengyi, Richards, Kay, Kurniawan, Nyoman D., Petrou, Steven and Reutens, David C. (2012). MRI-guided volume reconstruction of mouse brain from histological sections. Journal of Neuroscience Methods, 211 (2), 2010-2017. doi: 10.1016/j.jneumeth.2012.08.021
2012
Journal Article
Diffusion-weighted magnetic resonance imaging detection of basal forebrain cholinergic degeneration in a mouse model
Kerbler, Georg M., Hamlin, Adam S., Pannek, Kerstin, Kurniawan, Nyoman D., Keller, Marianne D., Rose, Stephen E. and Coulson, Elizabeth J. (2012). Diffusion-weighted magnetic resonance imaging detection of basal forebrain cholinergic degeneration in a mouse model. NeuroImage, 66, 133-141. doi: 10.1016/j.neuroimage.2012.10.075
2012
Journal Article
Microscopic diffusion anisotropy in formalin fixed prostate tissue: Preliminary findings
Bourne, Roger M., Kurniawan, Nyoman, Cowin, Gary, Sved, Paul and Watson, Geoffrey (2012). Microscopic diffusion anisotropy in formalin fixed prostate tissue: Preliminary findings. Magnetic Resonance in Medicine, 68 (6), 1943-1948. doi: 10.1002/mrm.24179
2012
Journal Article
Segmentation of the C57BL/6J mouse cerebellum in magnetic resonance images
Ullmann, Jeremy F. P., Keller, Marianne D., Watson, Charles, Janke, Andrew L., Kurniawan, Nyoman D., Yang, Zhengyi, Richards, Kay, Paxinos, George, Egan, Gary F., Petrou, Steven, Bartlett, Perry, Galloway, Graham J. and Reutens, David C. (2012). Segmentation of the C57BL/6J mouse cerebellum in magnetic resonance images. NeuroImage, 62 (3), 1408-1414. doi: 10.1016/j.neuroimage.2012.05.061
2012
Journal Article
Biexponential diffusion decay in formalin-fixed prostate tissue: Preliminary findings
Bourne, Roger M., Kurniawan, Nyoman, Cowin, Gary, Stait-Gardner, Timothy, Sved, Paul, Watson, Geoffrey, Chowdhury, Supriya and Price, William S. (2012). Biexponential diffusion decay in formalin-fixed prostate tissue: Preliminary findings. Magnetic Resonance In Medicine, 68 (3), 954-959. doi: 10.1002/mrm.23291
2012
Journal Article
Microscopic diffusivity compartmentation in formalin-fixed prostate tissue
Bourne, Roger M., Kurniawan, Nyoman, Cowin, Gary, Stait-Gardner, Timothy, Sved, Paul, Watson, Geoffrey and Price, William S. (2012). Microscopic diffusivity compartmentation in formalin-fixed prostate tissue. Magnetic Resonance in Medicine, 68 (2), 614-620. doi: 10.1002/mrm.23244
2012
Journal Article
Association between congenital defects in papillary outgrowth and functional obstruction in Crim1 mutant mice
Wilkinson, Lorine, Kurniwan, Nyoman D., Phua, Yu Leng, Nguyen, Michael J., Li, Joan, Galloway, Graham J., Hashitani, Hikaru, Lang, Richard J. and Little, Melissa H. (2012). Association between congenital defects in papillary outgrowth and functional obstruction in Crim1 mutant mice. Journal of Pathology, 227 (4), 499-510. doi: 10.1002/path.4036
2012
Journal Article
Neuroanatomy and psychomimetic-induced locomotion in C57BL/6J and 129/X1SvJ mice exposed to developmental vitamin D deficiency
Harms, Lauren R., Cowin, Gary, Eyles, Darryl W., Kurniawan, Nyoman D., McGrath, John J. and Burne, Thomas H. J. (2012). Neuroanatomy and psychomimetic-induced locomotion in C57BL/6J and 129/X1SvJ mice exposed to developmental vitamin D deficiency. Behavioural Brain Research, 230 (1), 125-131. doi: 10.1016/j.bbr.2012.02.007
2012
Journal Article
Loss of neuronal potassium/chloride cotransporter 3 (KCC3) is responsible for the degenerative phenotype in a conditional mouse model of hereditary motor and sensory neuropathy associated with agenesis of the corpus callosum
Shekarabi, Masoud, Moldrich, Randal X., Rasheed, Sarah, Salin-Cantegrel, Adele, Laganiere, Janet, Rochefort, Daniel, Hince, Pascale, Huot, Karine, Gaudet, Rebecca, Kurniawan, Nyoman, Sotocinal, Susana G., Ritchie, Jennifer, Dion, Patrick A., Mogil, Jeffrey S., Richards, Linda J. and Rouleau, Guy A. (2012). Loss of neuronal potassium/chloride cotransporter 3 (KCC3) is responsible for the degenerative phenotype in a conditional mouse model of hereditary motor and sensory neuropathy associated with agenesis of the corpus callosum. Journal of Neuroscience, 32 (11), 3865-3876. doi: 10.1523/JNEUROSCI.3679-11.2012
2012
Journal Article
Super-resolution track-density imaging studies of mouse brain: Comparison to histology
Calamante, Fernando, Tournier, Jacques-Donald, Kurniawan, Nyoman D., Yang, Zhengyi, Gyengesi, Erika, Galloway, Graham J., Reutens, David C. and Connelly, Alan (2012). Super-resolution track-density imaging studies of mouse brain: Comparison to histology. NeuroImage, 59 (1), 286-296. doi: 10.1016/j.neuroimage.2011.07.014
2012
Conference Publication
Complement C3 Upregulation Contributes to a Sustained Inflammatory Response and Perpetuation of Seizure Foci in a Pilocarpine Model of Temporal Lobe Epilepsy
Kharatishvili, I., She, D., Shan, Z., Kurniawan, N. and Reutens, D. (2012). Complement C3 Upregulation Contributes to a Sustained Inflammatory Response and Perpetuation of Seizure Foci in a Pilocarpine Model of Temporal Lobe Epilepsy. 10th European Congress on Epileptology, London England, 30 September-4 October 2012. Hoboken, NJ United States: Wiley-Blackwell Publishing. doi: 10.1111/j.1528-1167.2012.03677.x
2012
Conference Publication
Maternal Ethanol Consumption Affects Offspring Epigenotype and Phenotype in the Mouse
Zhang, C., Yamada, L., Ho, M. F., Kaminen-Ahola, N., Ahola, A., Maga, M., Kurniawan, N., Galloway, G., Cox, T., Whitelaw, E. and Chong, S. (2012). Maternal Ethanol Consumption Affects Offspring Epigenotype and Phenotype in the Mouse. 16th World Congress of the International-Society for Biomedical Research on Alcoholism (ISBRA), Sapporo Japan, 09-12 September 2012. Hoboken, NJ, United States: Wiley-Blackwell. doi: 10.1111/j.1530-0277.2012.01917.x
2012
Conference Publication
Diffusion weighted imaging of zebrafish embryos using dedicated radio frequency coils
Ariens, Miriam, Ullmann, Jeremy, Kurniawan, Nyoman, Lo, Harriet, Reutens, David and Vegh, Viktor (2012). Diffusion weighted imaging of zebrafish embryos using dedicated radio frequency coils. 20th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Melbourme, VIC, Australia, 5-11 May 2012.
2012
Conference Publication
Probabilistic atlas of the C57BL/6J mouse cerebellum
Ullmann, J. F. P., Janke, A. L., Watson, C., Kurniawan, N. D., Paxinos, G., Keller, M, Yang, Z., Richards, K., Egan, G., Petrou, S., Galloway, G. and Reutens, D. (2012). Probabilistic atlas of the C57BL/6J mouse cerebellum. 20th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Melbourme, VIC, Australia, 5-11 May 2012.
2012
Conference Publication
Visualization of mouse barrel cortex using ex-vivo track density imaging
Kurniawan, Nyoman D., Yang, Zhengyi, Richards, Kay, Calamante, Fernando, Ullmann, Jeremy F. P., Galloway, Graham J., Petrou, Steven and Reutens, David C. (2012). Visualization of mouse barrel cortex using ex-vivo track density imaging. 20th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Melbourme, VIC, Australia, 5-11 May 2012.
2012
Conference Publication
Maternal ethanol consumption affects offspring epigenotype and phenotype in the mouse
Kaminen-Ahola, N., Ahola, A., Maga, M., Zhang, C., Yamada, L., Kurniawan, N., Galloway, G., Cox, T., Whitelaw, E. and Chong, S. (2012). Maternal ethanol consumption affects offspring epigenotype and phenotype in the mouse. 35th Annual Scientific Meeting of the Research Society on Alcoholism (RSA), San Francisco, CA, United States, 23-27 June 2012. Hoboken, NJ, United States: Wiley-Blackwell Publishing. doi: 10.1111/j.1530-0277.2012.01804.x
2012
Conference Publication
Structural magnetic resonance imaging of zebrafish brain using dedicated radio frequency microcoils
Vegh, Viktor, Ariens, Miriam, Ullmann, Jeremy, Kurniawan, Nyoman and Reutens, David (2012). Structural magnetic resonance imaging of zebrafish brain using dedicated radio frequency microcoils. 20th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Melbourme, VIC, Australia, 5-11 May 2012.
Funding
Current funding
Supervision
Availability
- Dr Nyoman Kurniawan is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
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Developing novel methods of kidney MRI acquisition and image analysis using artificial intelligence
Nephrons are the basic functional unit of the kidney, an organ with a central role in maintaining homeostasis in the body. The number of nephrons in the kidneys and their microstructure reflect the success of renal development and the trajectory of renal health through life. Low nephron number increases the risk of chronic kidney disease, hypertension and cardiovascular disease.
Current methods for nephron quantitation are limited to ex vivo methods which are labour intensive, affected by shrinkage or use contrast agents. Magnetic Resonance Imaging (MRI) has strong potential to characterise kidney microstructures, but in vivo it suffers from low image resolution and motion artefacts. This PhD project aims to develop novel methods for kidney MR image acquisitions and analyses using artificial intelligence (such as Deep Learning and super resolution methods) to allow characterisation of key components of nephrons, the glomeruli and tubules. It is expected that these new methods will play important roles in future kidney research and contribute to reducing Australia’s epidemic of chronic kidney disease.
This is an opportunity to work with researchers at the Centre for Advanced Imaging, a leading imaging research facility in Australia, and The University of Queensland School of Information Technology and Electrical Engineering.
The project will suit an enthusiastic and highly motivated student with a background in computer science, physics or engineering.
Supervision history
Current supervision
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Doctor Philosophy
Mapping human cervical spinal cord using high resolution structural and diffusion magnetic resonance imaging
Principal Advisor
Other advisors: Dr Gary Cowin
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Doctor Philosophy
Machine learning methods for visualisation and quantification of nephrons with MRI.
Associate Advisor
Other advisors: Dr Shakes Chandra
Completed supervision
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2024
Doctor Philosophy
Development of Diffusion MRI and Tractography Protocols to Characterise Mouse Brain Development
Principal Advisor
Other advisors: Professor Michael Piper
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2023
Doctor Philosophy
Multimodal MRI to monitor disease and treatment in a chronic-progressive EAE mouse model of multiple sclerosis
Principal Advisor
Other advisors: Dr Gary Cowin, Dr Nemat Khan
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2019
Doctor Philosophy
Advanced Diffusion Magnetic Resonance Imaging at Ultrahigh Field to Investigate Neurological Microstructural Changes in an EAE Mouse Model of Multiple Sclerosis
Principal Advisor
Other advisors: Emeritus Professor Maree Smith
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2018
Doctor Philosophy
Anatomical Study of the Human Cervical Spinal Cord and Pathology Assessment of Spinal Cord Injury in Animal Models Using Magnetic Resonance Imaging
Principal Advisor
Other advisors: Dr Gary Cowin, Professor Marc Ruitenberg
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2018
Doctor Philosophy
Neurological study of a mouse model of Fetal Alcohol Spectrum Disorders using advanced imaging techniques
Principal Advisor
Other advisors: Dr Karine Mardon
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2015
Doctor Philosophy
Development of magnetic resonance diffusion weighted imaging at 16.4T to assess neurological degeneration in a mouse model of multiple sclerosis
Principal Advisor
Other advisors: Emeritus Professor Maree Smith
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2020
Doctor Philosophy
The cardioprotective effects of growth hormone secretagogues in mouse models of myocardial ischemia reperfusion and infarction
Associate Advisor
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2017
Doctor Philosophy
Measuring the progression of upper motor neuron disease using diffusion MRI and its correlation with Clinical phenotype
Associate Advisor
Other advisors: Associate Professor Robert Henderson, Professor Pamela McCombe, Dr Kerstin Pannek
Media
Enquiries
Contact Dr Nyoman Kurniawan directly for media enquiries about:
- Imaging - MRI
- Magnetic Resonance Imaging
- MRI
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