Understanding the mechanism of Wolbachia-mediated antiviral protection (2010-2012)
Abstract
Pathogenic viruses that rely on insects for transmission between hosts cause many serious diseases in plants and animals. Understanding antiviral responses in insects is critical for strategies aimed at controlling insect virus transmission. We recently demonstrated that insects infected with the extremely common bacteria, Wolbachia are substantially protected from pathogenic viruses. This project will investigate the mechanisms that drive Wolbachia-mediated antiviral protection. This knowledge will significantly advance our understanding of control of virus infection in insects and will facilitate programs to control virus disease.
