New Antibiotics: Engaging Microbial Chemical Diversity (2012-2014)
Abstract
To maintain and improve the quality of life offered by modern health-care requires an ongoing commitment to the development of new drugs, to improve and replace those that have become less effective, and to bring to the community safer treatments for an ever-wider array of important diseases. This challenge is no more evident than in the case of infectious diseases, where rapidly emerging drug resistance has severely degraded the therapeutic value of existing antibiotics. This project will use innovative high throughput and high sensitivity technologies to assemble and explore a unique library of Australian microbes as a source of new chemical diversity, leading to the development of new antibiotics.
