Multiplexed Molecular Reading of Protein Associations via Nanoscaled Devices (2005-2007)
Abstract
The combinatorial interactions between proteins and other genomic biomolecules create the complexity of biology in all organisms. In order to fully understand their role these associations need to be studied in their native environment. Current technologies for exploring these associations however are limited or inadequate. In this project we aim to develop and test innovative nano-scaled devices to enable such studies in a high-throughput manner. As well as enabling a fundamental understanding of complex protein interactions this will lead to the enablement of many medical applications of proteomics such as rapid drug discovery processes and novel devices for diagnostic and clinical applications
