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The making of a sea shell: function and evolution of genes encoding calcareous architectures of phenomenal strength purity and beauty (2005-2007)

Abstract

Shells and skeletons of phenomenal strength purity and beauty are produced by a wide range of animals. These highly-order crystalline structures are genetically encoded. Here we investigate the molecular basis of microlaminate formation in mollusc shells. Using arguably the best model for biomineralisation - the abalone gastropod - we will characterise hundreds of genes encoding the structural and regulatory proteins that build shells with different structural properties. This investigation significantly expands our knowledge of the molecular cellular and evolutionary basis of biomineralisation and provides a foundation for a range of biotechnology innovations

Experts

Professor Bernard Degnan

Affiliate of Centre for Marine Science
Centre for Marine Science
Faculty of Science
Professorial Research Fellow
School of the Environment
Faculty of Science
Bernard Degnan
Bernard Degnan

Associate Professor Fiona Simpson

Affiliate Associate Professor of School of Chemistry and Molecular Biosciences
School of Chemistry and Molecular Biosciences
Faculty of Science
Affiliate Associate Professor of School of Biomedical Sciences
School of Biomedical Sciences
Faculty of Medicine
NHMRC Leadership Fellow
Frazer Institute
Faculty of Medicine
Fiona Simpson
Fiona Simpson