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The inhibition of muscle disuse atrophy in burrowing frogs (2006-2011)

Abstract

The aim of this project is to investigate the underlying regulatory mechanisms which inhibit muscle wasting in the green striped burrowing frog, Cyclorana alboguttata. We will take a novel integrative approach, examining physiological, biochemical and molecular processes associated with the inhibition of muscle atrophy in aestivating C. alboguttata, focusing on the role of metabolic depression, antioxidants and endogenous opioids. The significance of this study stems from utilising a unique animal model to examine the regulatory mechanisms that are associated with a natural inhibition of muscle atrophy.

Experts

Professor Craig Franklin

Professor
School of the Environment
Faculty of Science
Affiliate of Centre for Marine Science
Centre for Marine Science
Faculty of Science
Craig Franklin
Craig Franklin