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2024

Journal Article

The Potential of Sugarcane Waste-Derived Cellulose Fibres as Haemostatic Agents

Malone, Siobhan, Yegappan, Ramanathan, Kijas, Amanda, Gemmell, Anna, Rowan, Alan, Rajah, Divya, Kim, Minjun, Lauko, Jan and Amiralian, Nasim (2024). The Potential of Sugarcane Waste-Derived Cellulose Fibres as Haemostatic Agents. Polymers, 16 (12) 1654, 1654. doi: 10.3390/polym16121654

The Potential of Sugarcane Waste-Derived Cellulose Fibres as Haemostatic Agents

2023

Journal Article

Entry and exit of extracellular vesicles to and from the blood circulation

Iannotta, Dalila, A, Amruta, Kijas, Amanda W., Rowan, Alan E. and Wolfram, Joy (2023). Entry and exit of extracellular vesicles to and from the blood circulation. Nature Nanotechnology, 19 (1), 137-20. doi: 10.1038/s41565-023-01522-z

Entry and exit of extracellular vesicles to and from the blood circulation

2023

Journal Article

Snake venom-defined fibrin architecture dictates fibroblast survival and differentiation

Wang, Zhao, Lauko, Jan, Kijas, Amanda W., Gilbert, Elliot P., Turunen, Petri, Yegappan, Ramanathan, Zou, Dongxiu, Mata, Jitendra and Rowan, Alan E. (2023). Snake venom-defined fibrin architecture dictates fibroblast survival and differentiation. Nature Communications, 14 (1) 1029, 1-16. doi: 10.1038/s41467-023-36437-9

Snake venom-defined fibrin architecture dictates fibroblast survival and differentiation

2022

Journal Article

Snake venom hydrogels as a rapid hemostatic agent for uncontrolled bleeding

Yegappan, Ramanathan, Lauko, Jan, Wang, Zhao, Lavin, Martin F., Kijas, Amanda W. and Rowan, Alan E. (2022). Snake venom hydrogels as a rapid hemostatic agent for uncontrolled bleeding. Advanced Healthcare Materials, 11 (15) 2200574, 2200574. doi: 10.1002/adhm.202200574

Snake venom hydrogels as a rapid hemostatic agent for uncontrolled bleeding

2022

Journal Article

The Mechanosensory Role of Osteocytes and Implications for Bone Health and Disease States

Choi, Jung Un Ally, Kijas, Amanda W., Lauko, Jan and Rowan, Alan E. (2022). The Mechanosensory Role of Osteocytes and Implications for Bone Health and Disease States. Frontiers in Cell and Developmental Biology, 9 770143, 770143. doi: 10.3389/fcell.2021.770143

The Mechanosensory Role of Osteocytes and Implications for Bone Health and Disease States

2021

Journal Article

Heterodyne Brillouin microscopy for biomechanical imaging

Taylor, Michael A., Kijas, Amanda W., Wang, Zhao, Lauko, Jan and Rowan, Alan E. (2021). Heterodyne Brillouin microscopy for biomechanical imaging. Biomedical Optics Express, 12 (10) 6259, 6259-6268. doi: 10.1364/boe.435869

Heterodyne Brillouin microscopy for biomechanical imaging

2020

Journal Article

Correction of ATM mutations in iPS cells from two ataxia-telangiectasia patients restores DNA damage and oxidative stress responses

Ovchinnikov, Dmitry A., Withey, Sarah L., Leeson, Hannah C., Lei, U. Wang, Sundarrajan, Ashmitha, Junday, Keerat, Pewarchuk, Michelle, Yeo, Abrey J., Kijas, Amanda W., Lavin, Martin F. and Wolvetang, Ernst J. (2020). Correction of ATM mutations in iPS cells from two ataxia-telangiectasia patients restores DNA damage and oxidative stress responses. Human Molecular Genetics, 29 (6), 990-1001. doi: 10.1093/hmg/ddaa023

Correction of ATM mutations in iPS cells from two ataxia-telangiectasia patients restores DNA damage and oxidative stress responses

2020

Journal Article

Simultaneous targeting of DNA replication and homologous recombination in glioblastoma with a polyether ionophore

Lim, Yi Chieh, Ensbey, Kathleen S., Offenhäuser, Carolin, D'souza, Rochelle C. J., Cullen, Jason K., Stringer, Brett W., Quek, Hazel, Bruce, Zara C., Kijas, Amanda, Cianfanelli, Valentina, Mahboubi, Bijan, Smith, Fiona, Jeffree, Rosalind L., Wiesmüeller, Lisa, Wiegmans, Adrian P., Bain, Amanda, Lombard, Fanny J., Roberts, Tara L., Khanna, Kum Kum, Lavin, Martin F., Kim, Baek, Hamerlik, Petra, Johns, Terrance G., Coster, Mark J., Boyd, Andrew W. and Day, Bryan W. (2020). Simultaneous targeting of DNA replication and homologous recombination in glioblastoma with a polyether ionophore. Neuro-Oncology, 22 (2), 216-228. doi: 10.1093/neuonc/noz159

Simultaneous targeting of DNA replication and homologous recombination in glioblastoma with a polyether ionophore

2017

Book Chapter

Assaying for radioresistant DNA synthesis, the hallmark feature of the intra-S-phase checkpoint using a DNA fiber technique

Kijas, Amanda W. and Lavin, Martin F. (2017). Assaying for radioresistant DNA synthesis, the hallmark feature of the intra-S-phase checkpoint using a DNA fiber technique. ATM kinase: methods and protocols. (pp. 13-23) edited by Sergei V. Kozlov. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-6955-5_2

Assaying for radioresistant DNA synthesis, the hallmark feature of the intra-S-phase checkpoint using a DNA fiber technique

2016

Journal Article

Therapeutic targets and investigated treatments for Ataxia-Telangiectasia

Lavin, Martin F., Yeo, Abrey J., Kijas, Amanda W., Wolvetang, Ernst, Sly, Peter D., Wainwright, Claire and Sinclair, Kate (2016). Therapeutic targets and investigated treatments for Ataxia-Telangiectasia. Expert Opinion on Orphan Drugs, 4 (12), 1263-1276. doi: 10.1080/21678707.2016.1254618

Therapeutic targets and investigated treatments for Ataxia-Telangiectasia

2015

Journal Article

ATM-dependent phosphorylation of all three members of the MRN complex: from sensor to adaptor

Lavin, Martin F., Kozlov, Sergei, Gatei, Magtouf and Kijas, Amanda W. (2015). ATM-dependent phosphorylation of all three members of the MRN complex: from sensor to adaptor. Biomolecules, 5 (4) A31, 2877-2902. doi: 10.3390/biom5042877

ATM-dependent phosphorylation of all three members of the MRN complex: from sensor to adaptor

2015

Journal Article

ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1

Kijas, Amanda W., Lim, Yi Chieh, Bolderson, Emma, Cerosaletti, Karen, Gatei, Magtouf, Jakob, Burkhard, Tobias, Frank, Taucher-Scholz, Gisela, Gueven, Nuri, Oakley, Greg, Concannon, Patrick, Wolvetang, Ernst, Khanna, Kum Kum, Wiesmuller, Lisa and Lavin, Martin F. (2015). ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1. Nucleic Acids Research, 43 (17), 8352-8367. doi: 10.1093/nar/gkv754

ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1

2014

Journal Article

RAD50 phosphorylation promotes ATR downstream signaling and DNA restart following replication stress

Gatei, Magtouf, Kijas, Amanda W., Biard, Denis, Dork, Thilo and Lavin, Martin F. (2014). RAD50 phosphorylation promotes ATR downstream signaling and DNA restart following replication stress. Human Molecular Genetics, 23 (16) ddu141, 4232-4248. doi: 10.1093/hmg/ddu141

RAD50 phosphorylation promotes ATR downstream signaling and DNA restart following replication stress

2013

Journal Article

A patient-derived olfactory stem cell disease model for ataxia-telangiectasia

Stewart, Romal, Kozlov, Sergei, Matigian, Nicholas, Wali, Gautam, Gatei, Magtouf, Sutharsan, Ratneswary, Bellette, Bernadette, Kijas, Amanda Wraith, Cochrane, Julie, Coulthard, Mark, Perry, Chris, Sinclair, Kate, Mackay-Sim, Alan and Lavin, Martin F. (2013). A patient-derived olfactory stem cell disease model for ataxia-telangiectasia. Human Molecular Genetics, 22 (12), 2495-2509. doi: 10.1093/hmg/ddt101

A patient-derived olfactory stem cell disease model for ataxia-telangiectasia

2012

Journal Article

A role for homologous recombination and abnormal cell-cycle progression in radioresistance of glioma-initiating cells

Lim, Yi Chieh, Roberts, Tara L., Day, Bryan W., Harding, Angus, Kozlov, Sergei, Kijas, Amanda W., Ensbey, Kathleen S., Walker, David G. and Lavin, Martin F. (2012). A role for homologous recombination and abnormal cell-cycle progression in radioresistance of glioma-initiating cells. Molecular Cancer Therapeutics, 11 (9), 1863-1872. doi: 10.1158/1535-7163.MCT-11-1044

A role for homologous recombination and abnormal cell-cycle progression in radioresistance of glioma-initiating cells

2012

Conference Publication

Response of glioma initiating cells to ionising radiation

Lim, Y. C., Roberts, T., Day, B., Harding, A., Ensbey, K., Kozlov, S., Kijas, A., Walker, D. and Lavin, M. (2012). Response of glioma initiating cells to ionising radiation. Targeting Cancer from Diagnosis to Cure & 5th Annual COGNO Annual Scientific Meeting, Brisbane, QLD, Australia, 8-10 August 2012. Chichester, West Sussex, United Kingdom: Wiley-Blackwell. doi: 10.1111/j.1743-7563.2012.01586_2.x

Response of glioma initiating cells to ionising radiation

2011

Journal Article

ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control

Gatei, Magtouf, Jakob, Burkhard, Chen, Philip, Kijas, Amanda W., Becherel, Olivier J., Gueven, Nuri, Birrell, Geoff, Lee, Ji-Hoon, Paull, Tanya T., Lerenthal, Yaniv, Fazry, Shazrul, Taucher-Scholtz, Gisela, Kalb, Reinhard, Schindler, Detlev, Waltes, Regina, Doerk, Thilo and Lavin, Martin F. (2011). ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control. Journal of Biological Chemistry, 286 (36), 31542-31556. doi: 10.1074/jbc.M111.258152

ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control

2011

Journal Article

Autophosphorylation and ATM activation: Additional sites add to the complexity

Kozlov, Sergei V., Graham, Mark E., Jakob, Burkhard, Tobias, Frank, Kijas, Amanda W., Tanuji, Marcel, Chen, Philip, Robinson, Phillip J., Taucher-Scholz, Gisela, Suzuki, Keiji, So, Sairai, Chen, David and Lavin, Martin F. (2011). Autophosphorylation and ATM activation: Additional sites add to the complexity. The Journal of Biological Chemistry, 286 (11), 9107-9119. doi: 10.1074/jbc.M110.204065

Autophosphorylation and ATM activation: Additional sites add to the complexity

2010

Journal Article

CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response

Becherel, Olivier J., Jakob, Burkhard, Cherry, Amy L., Gueven, Nuri, Fusser, Markus, Kijas, Amanda W., Peng, Cheng, Katyal, Sachin, McKinnon, Peter J., Chen, Junjie, Epe, Bernd, Smerdon, Stephen J., Taucher-Scholz, Gisela and Lavin, Martin F. (2010). CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response. Nucleic Acids Research, 38 (5) gkp1149, 1489-1503. doi: 10.1093/nar/gkp1149

CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response

2010

Book Chapter

ATM mediated signaling defends the integrity of the genome

Lavin, Martin F., Gatei, Magtouf, Chen, Philip, Kijas, Amanda and Kozlov, Sergei (2010). ATM mediated signaling defends the integrity of the genome. Handbook of Cell Signaling. (pp. 2171-2183) edited by Ralph A. Bradshaw and Edward A. Dennis. Amsterdam, The Netherlands: Elsevier Inc.. doi: 10.1016/B978-0-12-374145-5.00263-1

ATM mediated signaling defends the integrity of the genome