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2021 Journal Article A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA virusesAmarilla, Alberto A., Sng, Julian D. J., Parry, Rhys, Deerain, Joshua M., Potter, James R., Setoh, Yin Xiang, Rawle, Daniel J., Le, Thuy T., Modhiran, Naphak, Wang, Xiaohui, Peng, Nias Y. G., Torres, Francisco J., Pyke, Alyssa, Harrison, Jessica J., Freney, Morgan E., Liang, Benjamin, McMillan, Christopher L. D., Cheung, Stacey T. M., Guevara, Darwin J Da Costa, Hardy, Joshua M., Bettington, Mark, Muller, David A., Coulibaly, Fasséli, Moore, Frederick, Hall, Roy A., Young, Paul R., Mackenzie, Jason M., Hobson-Peters, Jody, Suhrbier, Andreas ... Khromykh, Alexander A. (2021). A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses. Nature Communications, 12 (1) 3431, 3431. doi: 10.1038/s41467-021-23779-5 |
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2021 Journal Article A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic virusesHardy, Joshua M., Newton, Natalee D., Modhiran, Naphak, Scott, Connor A. P., Venugopal, Hariprasad, Vet, Laura J., Young, Paul R., Hall, Roy A., Hobson-Peters, Jody, Coulibaly, Fasséli and Watterson, Daniel (2021). A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses. Nature Communications, 12 (1) 3266, 3266. doi: 10.1038/s41467-021-22773-1 |
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2021 Journal Article A chimeric dengue virus vaccine candidate delivered by high density microarray patches protects against infection in miceChoo, Jovin J. Y., Vet, Laura J., McMillan, Christopher L. D., Harrison, Jessica J., Scott, Connor A. P., Depelsenaire, Alexandra C. I., Fernando, Germain J. P., Watterson, Daniel, Hall, Roy A., Young, Paul R., Hobson-Peters, Jody and Muller, David A. (2021). A chimeric dengue virus vaccine candidate delivered by high density microarray patches protects against infection in mice. npj Vaccines, 6 (1) 66, 66. doi: 10.1038/s41541-021-00328-1 |
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2021 Journal Article The structure of an infectious immature flavivirus redefines viral architecture and maturationNewton, Natalee D., Hardy, Joshua M., Modhiran, Naphak, Hugo, Leon E., Amarilla, Alberto A., Bibby, Summa, Venugopal, Hariprasad, Harrison, Jessica J., Traves, Renee J., Hall, Roy A., Hobson-Peters, Jody, Coulibaly, Fasséli and Watterson, Daniel (2021). The structure of an infectious immature flavivirus redefines viral architecture and maturation. Science Advances, 7 (20) eabe4507, 1-12. doi: 10.1126/sciadv.abe4507 |
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2021 Journal Article Assessing the potential of unmanned aerial vehicle spraying of aqueous ozone as an outdoor disinfectant for SARS-CoV-2Albert, Simon, Amarilla, Alberto A., Trollope, Ben, Sng, Julian D.J., Setoh, Yin Xiang, Deering, Nathaniel, Modhiran, Naphak, Weng, Sung-Hsia, Melo, Maria C., Hutley, Nicholas, Nandy, Avik, Furlong, Michael J., Young, Paul R., Watterson, Daniel, Grinham, Alistair R. and Khromykh, Alexander A. (2021). Assessing the potential of unmanned aerial vehicle spraying of aqueous ozone as an outdoor disinfectant for SARS-CoV-2. Environmental Research, 196 110944, 110944. doi: 10.1016/j.envres.2021.110944 |
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2021 Journal Article Preclinical development of a molecular clamp-stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2Watterson, Daniel, Wijesundara, Danushka K., Modhiran, Naphak, Mordant, Francesca L., Li, Zheyi, Avumegah, Michael S., McMillan, Christopher L. D., Lackenby, Julia, Guilfoyle, Kate, van Amerongen, Geert, Stittelaar, Koert, Cheung, Stacey T. M., Bibby, Summa, Daleris, Mallory, Hoger, Kym, Gillard, Marianne, Radunz, Eve, Jones, Martina L., Hughes, Karen, Hughes, Ben, Goh, Justin, Edwards, David, Scoble, Judith, Pearce, Lesley, Kowalczyk, Lukasz, Phan, Tram, La, Mylinh, Lu, Louis, Pham, Tam ... Chappell, Keith J. (2021). Preclinical development of a molecular clamp-stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2. Clinical & Translational Immunology, 10 (4) e1269, e1269. doi: 10.1002/cti2.1269 |
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2021 Journal Article Discovery of sisunatovir (RV521), an inhibitor of respiratory syncytial virus fusionCockerill, G. Stuart, Angell, Richard M., Bedernjak, Alexandre, Chuckowree, Irina, Fraser, Ian, Gascon-Simorte, Jose, Gilman, Morgan S. A., Good, James A. D., Harland, Rachel, Johnson, Sara M., Ludes-Meyers, John H., Littler, Edward, Lumley, James, Lunn, Graham, Mathews, Neil, McLellan, Jason S., Paradowski, Michael, Peeples, Mark E., Scott, Claire, Tait, Dereck, Taylor, Geraldine, Thom, Michelle, Thomas, Elaine, Villalonga Barber, Carol, Ward, Simon E., Watterson, Daniel, Williams, Gareth, Young, Paul and Powell, Kenneth (2021). Discovery of sisunatovir (RV521), an inhibitor of respiratory syncytial virus fusion. Journal of Medicinal Chemistry, 64 (7) acs.jmedchem.0c01882, 3658-3676. doi: 10.1021/acs.jmedchem.0c01882 |
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2021 Journal Article Epidemiology of respiratory syncytial virus in a community birth cohort of infants in the first 2 years of lifeTakashima, Mari D., Grimwood, Keith, Sly, Peter D., Lambert, Stephen B., Chappell, Keith J., Watterson, Daniel and Ware, Robert S. (2021). Epidemiology of respiratory syncytial virus in a community birth cohort of infants in the first 2 years of life. European Journal of Pediatrics, 180 (7), 2125-2135. doi: 10.1007/s00431-021-03998-0 |
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2021 Journal Article An optimized high-throughput immuno-plaque assay for SARS-CoV-2Amarilla, Alberto A., Modhiran, Naphak, Setoh, Yin Xiang, Peng, Nias Y. G., Sng, Julian D. J., Liang, Benjamin, McMillan, Christopher L. D., Freney, Morgan E, Cheung, Stacey T. M., Chappell, Keith J., Khromykh, Alexander A., Young, Paul R. and Watterson, Daniel (2021). An optimized high-throughput immuno-plaque assay for SARS-CoV-2. Frontiers in Microbiology, 12 625136, 625136. doi: 10.3389/fmicb.2021.625136 |
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2021 Journal Article Adjuvant selection for influenza and RSV prefusion subunit vaccinesIsaacs, Ariel, Li, Zheyi, Cheung, Stacey T. M., Wijesundara, Danushka K., McMillan, Christopher L. D., Modhiran, Naphak, Young, Paul R., Ranasinghe, Charani, Watterson, Daniel and Chappell, Keith J. (2021). Adjuvant selection for influenza and RSV prefusion subunit vaccines. Vaccines, 9 (2) 71, 1-14. doi: 10.3390/vaccines9020071 |
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2021 Journal Article A broadly protective antibody that targets the flavivirus NS1 proteinModhiran, Naphak, Song, Hao, Liu, Lidong, Bletchly, Cheryl, Brillault, Lou, Amarilla, Alberto A., Xu, Xiaoying, Qi, Jianxun, Chai, Yan, Cheung, Stacey T. M., Traves, Renee, Setoh, Yin Xiang, Bibby, Summa, Scott, Connor A. P., Freney, Morgan E., Newton, Natalee D., Khromykh, Alexander A., Chappell, Keith J., Muller, David A., Stacey, Katryn J., Landsberg, Michael J., Shi, Yi, Gao, George F., Young, Paul R. and Watterson, Daniel (2021). A broadly protective antibody that targets the flavivirus NS1 protein. Science, 371 (6525), 190-194. doi: 10.1126/science.abb9425 |
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2021 Journal Article The next generation of influenza vaccines: towards a universal solutionMcMillan, Christopher L. D., Young, Paul R., Watterson, Daniel and Chappell, Keith J. (2021). The next generation of influenza vaccines: towards a universal solution. Vaccines, 9 (1) 26, 1-20. doi: 10.3390/vaccines9010026 |
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2020 Journal Article Rapid response subunit vaccine design in the absence of structural informationWijesundara, Danushka K., Avumegah, Michael S., Lackenby, Julia, Modhiran, Naphak, Isaacs, Ariel, Young, Paul R., Watterson, Daniel and Chappell, Keith J. (2020). Rapid response subunit vaccine design in the absence of structural information. Frontiers in Immunology, 11 592370, 592370. doi: 10.3389/fimmu.2020.592370 |
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2020 Journal Article Micro-fusion inhibition tests: quantifying antibody neutralization of virus-mediated cell–cell fusionThakur, Nazia, Conceicao, Carina, Isaacs, Ariel, Human, Stacey, Modhiran, Naphak, McLean, Rebecca K., Pedrera, Miriam, Tan, Tiong Kit, Rijal, Pramila, Townsend, Alain, Taylor, Geraldine, Young, Paul R., Watterson, Daniel, Chappell, Keith J., Graham, Simon P. and Bailey, Dalan (2020). Micro-fusion inhibition tests: quantifying antibody neutralization of virus-mediated cell–cell fusion. Journal of General Virology, 102 (1) 001506. doi: 10.1099/jgv.0.001506 |
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2020 Journal Article Genetic, morphological and antigenic relationships between mesonivirus isolates from Australian mosquitoes and evidence for their horizontal transmissionNewton, Natalee D., Colmant, Agathe M. G., O’Brien, Caitlin A., Ledger, Emma, Paramitha, Devina, Bielefeldt-Ohmann, Helle, Watterson, Daniel, McLean, Breeanna J., Hall-Mendelin, Sonja, Warrilow, David, van den Hurk, Andrew F., Liu, Wenjun, Hoare, Christina, Kizu, Joanne R., Gauci, Penelope J., Haniotis, John, Doggett, Stephen L., Shaban, Babak, Johansen, Cheryl A., Hall, Roy A. and Hobson-Peters, Jody (2020). Genetic, morphological and antigenic relationships between mesonivirus isolates from Australian mosquitoes and evidence for their horizontal transmission. Viruses, 12 (10) 1159, 1159. doi: 10.3390/v12101159 |
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2020 Journal Article A unique relative of Rotifer birnavirus Isolated from Australian mosquitoesO’Brien, Caitlin A., Pegg, Cassandra L., Nouwens, Amanda S., Bielefeldt-Ohmann, Helle, Huang, Bixing, Warrilow, David, Harrison, Jessica J., Haniotis, John, Schulz, Benjamin L., Paramitha, Devina, Colmant, Agathe M. G., Newton, Natalee D., Doggett, Stephen L., Watterson, Daniel, Hobson-Peters, Jody and Hall, Roy A. (2020). A unique relative of Rotifer birnavirus Isolated from Australian mosquitoes. Viruses, 12 (9) 1056, 1056. doi: 10.3390/v12091056 |
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2020 Journal Article Bovine herpesvirus-4-vectored delivery of nipah virus glycoproteins enhances T cell immunogenicity in pigsPedrera, Miriam, Macchi, Francesca, McLean, Rebecca K., Franceschi, Valentina, Thakur, Nazia, Russo, Luca, Medfai, Lobna, Todd, Shawn, Tchilian, Elma Z., Audonnet, Jean-Christophe, Chappell, Keith, Isaacs, Ariel, Watterson, Daniel, Young, Paul R., Marsh, Glenn A., Bailey, Dalan, Graham, Simon P. and Donofrio, Gaetano (2020). Bovine herpesvirus-4-vectored delivery of nipah virus glycoproteins enhances T cell immunogenicity in pigs. Vaccines, 8 (1) 115, 115. doi: 10.3390/vaccines8010115 |
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2020 Journal Article Flow-cytometry detection of fluorescent magnetic nanoparticle clusters increases sensitivity of dengue immunoassaySanjaya, K.C., Ranzoni, Andrea, Hung, Jacky, Blaskovich, Mark A.T., Watterson, Daniel, Young, Paul R. and Cooper, Matthew A. (2020). Flow-cytometry detection of fluorescent magnetic nanoparticle clusters increases sensitivity of dengue immunoassay. Analytica Chimica Acta, 1107, 85-91. doi: 10.1016/j.aca.2020.02.007 |
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2020 Journal Article Novel monoclonal antibodies against Australian strains of negeviruses and insights into virus structure, replication and host -restrictionColmant, Agathe M. G., O'Brien, Caitlin A., Newton, Natalee D., Watterson, Daniel, Hardy, Joshua, Coulibaly, Fasséli, Bielefeldt-Ohmann, Helle, Warrilow, David, Huang, Bixing, Paramitha, Devina, Harrison, Jessica J., Hall, Roy A. and Hobson-Peters, Jody (2020). Novel monoclonal antibodies against Australian strains of negeviruses and insights into virus structure, replication and host -restriction. Journal of General Virology, 101 (4), 440-452. doi: 10.1099/jgv.0.001388 |
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2019 Journal Article A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virusHobson-Peters, Jody, Harrison, Jessica J., Watterson, Daniel, Hazlewood, Jessamine E., Vet, Laura J., Newton, Natalee D., Warrilow, David, Colmant, Agathe M. G., Taylor, Carmel, Huang, Bixing, Piyasena, Thisun B. H., Chow, Weng Kong, Setoh, Yin Xiang, Tang, Bing, Nakayama, Eri, Yan, Kexin, Amarilla, Alberto A., Wheatley, Sarah, Moore, Peter R., Finger, Mitchell, Kurucz, Nina, Modhiran, Naphak, Young, Paul R., Khromykh, Alexander A., Bielefeldt-Ohmann, Helle, Suhrbier, Andreas and Hall, Roy A. (2019). A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus. Science Translational Medicine, 11 (522) eaax7888, 1-15. doi: 10.1126/scitranslmed.aax7888 |
