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2015

Journal Article

Effective heritable gene knockdown in zebrafish using synthetic microRNAs

Giacomotto, Jean, Rinkwitz, Silke and Becker, Thomas S. (2015). Effective heritable gene knockdown in zebrafish using synthetic microRNAs. Nature Communications, 6 (7378) 7378, 1-11. doi: 10.1038/ncomms8378

Effective heritable gene knockdown in zebrafish using synthetic microRNAs

2015

Journal Article

Motor neuron-expressed microRNAs 218 and their enhancers are nested within introns of Slit2/3 genes

Punnamoottil, Beena, Rinkwitz, Silke, Giacomotto, Jean, Svahn, Adam J. and Becker, Thomas S. (2015). Motor neuron-expressed microRNAs 218 and their enhancers are nested within introns of Slit2/3 genes. Genesis, 53 (5), 321-328. doi: 10.1002/dvg.22852

Motor neuron-expressed microRNAs 218 and their enhancers are nested within introns of Slit2/3 genes

2013

Journal Article

Chemical genetics unveils a key role of mitochondrial dynamics, cytochrome c release and ip3r activity in muscular dystrophy

Giacomotto, Jean, Brouilly, Nicolas, Walter, Ludivine, Mariol, Marie-Christine, Berger, Joachim, Segalat, Laurent, Becker, Thomas S., Currie, Peter D. and Gieseler, Kathrin (2013). Chemical genetics unveils a key role of mitochondrial dynamics, cytochrome c release and ip3r activity in muscular dystrophy. Human Molecular Genetics, 22 (22) ddt302, 4562-4578. doi: 10.1093/hmg/ddt302

Chemical genetics unveils a key role of mitochondrial dynamics, cytochrome c release and ip3r activity in muscular dystrophy

2012

Journal Article

Pax4 is not essential for beta-cell differentiation in zebrafish embryos but modulates alpha-cell generation by repressing arx gene expression

Djiotsa, Joachim, Verbruggen, Vincianne, Giacomotto, Jean, Ishibashi, Minaka, Manning, Elisabeth, Rinkwitz, Silke, Manfroid, Isabelle, Lvoz, Marianne L. and Peers, Bernard (2012). Pax4 is not essential for beta-cell differentiation in zebrafish embryos but modulates alpha-cell generation by repressing arx gene expression. BMC Developmental Biology, 12 (1) 37, 37.1-37.16. doi: 10.1186/1471-213X-12-37

Pax4 is not essential for beta-cell differentiation in zebrafish embryos but modulates alpha-cell generation by repressing arx gene expression

2011

Journal Article

Caenorhabditis elegans as a chemical screening tool for the study of neuromuscular disorders. Manual and semi-automated methods

Giacomotto, Jean, Segalat, Laurent, Carre-Pierrat, Maite and Gieseler, Kathrin (2011). Caenorhabditis elegans as a chemical screening tool for the study of neuromuscular disorders. Manual and semi-automated methods. Methods, 56 (1), 103-113. doi: 10.1016/j.ymeth.2011.10.010

Caenorhabditis elegans as a chemical screening tool for the study of neuromuscular disorders. Manual and semi-automated methods

2010

Journal Article

High-throughput screening and small animal models, where are we?

Giacomotto, Jean and Segalat, Laurent (2010). High-throughput screening and small animal models, where are we?. British Journal of Pharmacology, 160 (2), 204-216. doi: 10.1111/j.1476-5381.2010.00725.x

High-throughput screening and small animal models, where are we?

2009

Journal Article

Metabolic profiling strategy of Caenorhabditis elegans by whole-organism nuclear magnetic resonance

Blaise, Benjamin J., Giacomotto, Jean, Triba, Mohamed N., Toulhoat, Pierre, Piotto, Martial, Emsley, Lyndon, Segalat, Laurent, Dumas, Marc-Emmanuel and Elena, Benedicte (2009). Metabolic profiling strategy of Caenorhabditis elegans by whole-organism nuclear magnetic resonance. Journal of Proteome Research, 8 (5), 2542-2550. doi: 10.1021/pr900012d

Metabolic profiling strategy of Caenorhabditis elegans by whole-organism nuclear magnetic resonance

2009

Journal Article

Evaluation of the therapeutic potential of carbonic anhydrase inhibitors in two animal models of dystrophin deficient muscular dystrophy

Giacomotto, Jean, Pertl, Cordula, Borrel, Caroline, Walter, Maggie C., Bulst, Stefanie, Johnsen, Bob, Baillie, David L., Lochmuller, Hanns, Thirion, Christian and Segalat, Laurent (2009). Evaluation of the therapeutic potential of carbonic anhydrase inhibitors in two animal models of dystrophin deficient muscular dystrophy. Human Molecular Genetics, 18 (21), 4089-4101. doi: 10.1093/hmg/ddp358

Evaluation of the therapeutic potential of carbonic anhydrase inhibitors in two animal models of dystrophin deficient muscular dystrophy

2007

Journal Article

Metabotyping of Caenorhabditis elegans reveals latent phenotypes

Blaise, Benjamin J., Giacomotto, Jean, Elena, Benedicte, Dumas, Marc-Emmanuel, Toulhoat, Pierre, Segalat, Laurent and Emsley, Lyndon (2007). Metabotyping of Caenorhabditis elegans reveals latent phenotypes. Proceedings of the National Academy of Sciences of the United States of America, 104 (50), 19808-19812. doi: 10.1073/pnas.0707393104

Metabotyping of Caenorhabditis elegans reveals latent phenotypes

2006

Journal Article

Blocking of striated muscle degeneration by serotonin in C. elegans

Carre-Pierrat, Maite´, Mariol, Marie-Christine, Chambonnier, Lucie, Laugraud, Aurelie, Heskia, Fabienne, Giacomotto, Jean and Segalat, Laurent (2006). Blocking of striated muscle degeneration by serotonin in C. elegans. Journal of Muscle Research and Cell Motility, 27 (3-4), 253-258. doi: 10.1007/s10974-006-9070-9

Blocking of striated muscle degeneration by serotonin in C. elegans