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2015

Journal Article

High-antibody-producing Chinese hamster ovary cells up-regulate intracellular protein transport and glutathione synthesis

Orellana, Camila A., Marcellin, Esteban, Schulz, Benjamin L., Nouwens, Amanda S., Gray, Peter P. and Nielsen, Lars K. (2015). High-antibody-producing Chinese hamster ovary cells up-regulate intracellular protein transport and glutathione synthesis. Journal of Proteome Research, 14 (2), 609-618. doi: 10.1021/pr501027c

High-antibody-producing Chinese hamster ovary cells up-regulate intracellular protein transport and glutathione synthesis

2014

Journal Article

Intracellular trafficking pathways for nuclear delivery of plasmid DNA complexed with highly efficient endosome escape polymers

Gillard, Marianne, Jia, Zhongfan, Hou, Jeff Jia Cheng, Song, Michael, Gray, Peter P., Munro, Trent P. and Monteiro, Michael J. (2014). Intracellular trafficking pathways for nuclear delivery of plasmid DNA complexed with highly efficient endosome escape polymers. Biomacromolecules, 15 (10), 3569-3576. doi: 10.1021/bm5008376

Intracellular trafficking pathways for nuclear delivery of plasmid DNA complexed with highly efficient endosome escape polymers

2014

Journal Article

Polyethyleneimine-poly(ethylene glycol)-star-copolymers as efficient and biodegradable vectors for mammalian cell transfection

Ladewig, Katharina, Xu, Zhi Ping, Gray, Peter and Lu, G. Q. (Max) (2014). Polyethyleneimine-poly(ethylene glycol)-star-copolymers as efficient and biodegradable vectors for mammalian cell transfection. Journal of Biomedical Materials Research - Part A, 102 (7), 2137-2146. doi: 10.1002/jbm.a.34888

Polyethyleneimine-poly(ethylene glycol)-star-copolymers as efficient and biodegradable vectors for mammalian cell transfection

2014

Journal Article

Timed-release polymers as novel transfection reagents

Gillard, Marianne, Jia, Zhongfan, Gray, Peter P., Munro, Trent P. and Monteiro, Michael J. (2014). Timed-release polymers as novel transfection reagents. Polymer Chemistry, 5 (10), 3372-3378. doi: 10.1039/c4py00176a

Timed-release polymers as novel transfection reagents

2014

Journal Article

High-throughput ClonePix FL analysis of mAb-expressing clones using the UCOE expression system

Hou, Jeff Jia Cheng, Hughes, Ben S., Smede, Matthew, Leung, Kar Man, Levine, Kara, Rigby, Susan, Gray, Peter P. and Munro, Trent P. (2014). High-throughput ClonePix FL analysis of mAb-expressing clones using the UCOE expression system. New Biotechnology, 31 (3), 214-220. doi: 10.1016/j.nbt.2014.02.002

High-throughput ClonePix FL analysis of mAb-expressing clones using the UCOE expression system

2014

Journal Article

Thermoresponsive worms for expansion and release of human embryonic stem cells

Chen, Xiaoli, Prowse, Andrew B. J., Jia, Zhongfan, Tellier, Helena, Munro,Trent P., Gray, Peter P. and Monteiro, Michael J. (2014). Thermoresponsive worms for expansion and release of human embryonic stem cells. Biomacromolecules, 15 (3), 844-855. doi: 10.1021/bm401702h

Thermoresponsive worms for expansion and release of human embryonic stem cells

2013

Journal Article

Technoeconomic analysis of renewable aviation fuel from microalgae, Pongamia pinnata, and sugarcane

Klein-Marcuschamer, Daniel, Turner, Christopher, Allen, Mark, Gray, Peter, Dietzgen, Ralf G., Gresshoff, Peter M., Hankamer, Ben, Heimann, Kirsten, Scott, Paul T., Stephens, Evan, Speight, Robert and Nielsen, Lars K. (2013). Technoeconomic analysis of renewable aviation fuel from microalgae, Pongamia pinnata, and sugarcane. Biofuels, Bioproducts and Biorefining, 7 (4), 416-428. doi: 10.1002/bbb.1404

Technoeconomic analysis of renewable aviation fuel from microalgae, Pongamia pinnata, and sugarcane

2013

Journal Article

Selective inhibition of human group IIA-secreted phospholipase a 2 (hGIIA) signaling reveals arachidonic acid metabolism is associated with colocalization of hGIIA to vimentin in rheumatoid synoviocytes

Lee, Lawrence K., Bryant, Katherine J., Bouveret, Romaric, Lei, Pei-Wen, Duff, Anthony P., Harrop, Stephen J., Huang, Edwin P., Harvey, Richard P., Gelb, Michael H., Gray, Peter P., Curmi, Paul M., Cunningham, Anne M., Church, W. Bret and Scott, Kieran F. (2013). Selective inhibition of human group IIA-secreted phospholipase a 2 (hGIIA) signaling reveals arachidonic acid metabolism is associated with colocalization of hGIIA to vimentin in rheumatoid synoviocytes. Journal of Biological Chemistry, 288 (21), 15269-15279. doi: 10.1074/jbc.M112.397893

Selective inhibition of human group IIA-secreted phospholipase a 2 (hGIIA) signaling reveals arachidonic acid metabolism is associated with colocalization of hGIIA to vimentin in rheumatoid synoviocytes

2013

Journal Article

Flux balance analysis of CHO cells before and after a metabolic switch from lactate production to consumption

Martínez, Verónica S., Dietmair, Stefanie, Quek, Lake-Ee, Hodson, Mark P., Gray, Peter and Nielsen, Lars K. (2013). Flux balance analysis of CHO cells before and after a metabolic switch from lactate production to consumption. Biotechnology and Bioengineering, 110 (2), 660-666. doi: 10.1002/bit.24728

Flux balance analysis of CHO cells before and after a metabolic switch from lactate production to consumption

2012

Journal Article

Analysis of Mitochondrial Function and Localisation during Human Embryonic Stem Cell Differentiation In Vitro

Prowse, Andrew B. J., Chong, Fenny, Elliott, David A., Elefanty, Andrew G., Stanley, Edouard G., Gray, Peter P., Munro, Trent P. and Osborne, Geoffrey W. (2012). Analysis of Mitochondrial Function and Localisation during Human Embryonic Stem Cell Differentiation In Vitro. PLoS One, 7 (12) e52214, e52214-1-e52214-10. doi: 10.1371/journal.pone.0052214

Analysis of Mitochondrial Function and Localisation during Human Embryonic Stem Cell Differentiation In Vitro

2012

Journal Article

A multi-omics analysis of recombinant protein production in Hek293 cells

Dietmair, Stefanie, Hodson, Mark P., Quek, Lake-Ee, Timmins, Nicholas E., Gray, Peter and Nielsen, Lars K. (2012). A multi-omics analysis of recombinant protein production in Hek293 cells. Plos One, 7 (8) e43394, e43394.1-e43394.15. doi: 10.1371/journal.pone.0043394

A multi-omics analysis of recombinant protein production in Hek293 cells

2012

Journal Article

Metabolite profiling of CHO cells with different growth characteristics

Dietmair, Stefanie, Hodson, Mark P., Quek, Lake-Ee, Timmins, Nicholas E., Chrysanthopoulos, Panagiotis, Jacob, Shana S., Gray, Peter and Nielsen, Lars K. (2012). Metabolite profiling of CHO cells with different growth characteristics. Biotechnology and Bioengineering, 109 (6), 1404-1414. doi: 10.1002/bit.24496

Metabolite profiling of CHO cells with different growth characteristics

2012

Journal Article

Recombinant human albumin supports single cell cloning of CHO cells in chemically defined media

Zhu, Jiang, Wooh, Jong Wei, Hou, Jeff Jia Cheng, Hughes, Benjamin S., Gray, Peter P. and Munro, Trent P. (2012). Recombinant human albumin supports single cell cloning of CHO cells in chemically defined media. Biotechnology Progress, 28 (3), 887-891. doi: 10.1002/btpr.1549

Recombinant human albumin supports single cell cloning of CHO cells in chemically defined media

2012

Book Chapter

An optimised transfection platform for the Epi-CHO transient expression system in serum-free media

Codamo, Joe, Munro, Trent P., Hughes, Benjamin S., Song, Michael and Gray, Peter P. (2012). An optimised transfection platform for the Epi-CHO transient expression system in serum-free media. Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009. (pp. 19-23) edited by Nigel Jenkins, Niall Barron and Paula Alves. Dordrecht, Netherlands: Springer. doi: 10.1007/978-94-007-0884-6_3

An optimised transfection platform for the Epi-CHO transient expression system in serum-free media

2012

Book Chapter

Metabolomic analysis of CHO cultures with different growth characteristics – development of a metabolite extraction protocol for suspension adapted mammalian cells

Dietmair, Stefanie, Timmins, Nicholas E., Chrysanthopoulos, Panagiotis, Gray, Peter P., Krömer, Jens O. and Nielsen, Lars K. (2012). Metabolomic analysis of CHO cultures with different growth characteristics – development of a metabolite extraction protocol for suspension adapted mammalian cells. Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009. (pp. 37-41) edited by Nigel Jenkins, Niall Barron and Paula Alves. Dordrecht, Netherlands: Springer.

Metabolomic analysis of CHO cultures with different growth characteristics – development of a metabolite extraction protocol for suspension adapted mammalian cells

2012

Book Chapter

Analysis of protein expression via alternate 3’ Untranslated Region (UTR) signals through the use of site specific recombination

Hou, Jeff Jia Cheng, Song, Michael, Munro, Trent P. and Gray, Peter P. (2012). Analysis of protein expression via alternate 3’ Untranslated Region (UTR) signals through the use of site specific recombination. Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009. (pp. 47-51) edited by Nigel Jenkins, Niall Barron and Paula Alves. Dordrecht, Netherlands: Springer. doi: 10.1007/978-94-007-0884-6_8

Analysis of protein expression via alternate 3’ Untranslated Region (UTR) signals through the use of site specific recombination

2011

Journal Article

Bridging the gap: Facilities and technologies for development of early stage therapeutic mAb candidates

Munro, Trent P., Mahler, Stephen M., Huang, Edwin P., Chin, David Y. and Gray, Peter P. (2011). Bridging the gap: Facilities and technologies for development of early stage therapeutic mAb candidates. mAbs, 3 (5), 440-452. doi: 10.4161/mabs.3.5.16968

Bridging the gap: Facilities and technologies for development of early stage therapeutic mAb candidates

2011

Journal Article

Clonal selection of high producing, stably transfected HEK293 cell lines utilizing modified, high-throughput FACS screening

Song, Michael, Raphaelli, Kristin, Jones, Martina L., Aliabadi-Zadeh, Khosrow, Leung, Kar Man, Crowley, David, Hughes, Benjamin, Mahler, Stephen, Gray, Peter P., Huang, Edwin P. and Chin, David Y. (2011). Clonal selection of high producing, stably transfected HEK293 cell lines utilizing modified, high-throughput FACS screening. Journal of Chemical Technology and Biotechnology, 86 (7), 935-941. doi: 10.1002/jctb.2618

Clonal selection of high producing, stably transfected HEK293 cell lines utilizing modified, high-throughput FACS screening

2011

Journal Article

Efficient mAb production in CHO cells incorporating PEI-mediated transfection, mild hypothermia and the co-expression of XBP-1

Codamo, Joe, Hou, Jeff Jia Cheng, Hughes, Benjamin S., Gray, Peter P. and Munro, Trent P. (2011). Efficient mAb production in CHO cells incorporating PEI-mediated transfection, mild hypothermia and the co-expression of XBP-1. Journal of Chemical Technology and Biotechnology, 86 (7), 923-934. doi: 10.1002/jctb.2572

Efficient mAb production in CHO cells incorporating PEI-mediated transfection, mild hypothermia and the co-expression of XBP-1

2011

Journal Article

New frontiers in cell line development: Challenges for biosimilars

Hou, Jeff Jia Cheng, Codamo, Joe, Pilbrough, Warren, Hughes, Benjamin, Gray, Peter P. and Munro, Trent P. (2011). New frontiers in cell line development: Challenges for biosimilars. Journal of Chemical Technology and Biotechnology, 86 (7), 895-904. doi: 10.1002/jctb.2574

New frontiers in cell line development: Challenges for biosimilars