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2023 Journal Article An in vitro dynamic bioreactor model for evaluating antimicrobial effectiveness on periodontal polymicrobial biofilms: a proof-of-concept studyRamachandra, Srinivas Sulugodu, Sime, Fekade Bruck, Naicker, Saiyuri, Han, Pingping, Lee, Ryan S.B., Wallis, Steven C., Roberts, Jason A. and Ivanovski, Sašo (2023). An in vitro dynamic bioreactor model for evaluating antimicrobial effectiveness on periodontal polymicrobial biofilms: a proof-of-concept study. Journal of Periodontology, 95 (4), 384-396. doi: 10.1002/JPER.23-0086 |
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2023 Journal Article A protocol for an international, multicentre pharmacokinetic study for Screening Antifungal Exposure in Intensive Care Units: The SAFE-ICU studyRoberts, Jason A., Sime, Fekade, Lipman, Jeffrey, Hernández-Mitre, Maria Patricia, Baptista, João Pedro, Brüggemann, Roger J., Darvall, Jai, De Waele, Jan J., Dimopoulos, George, Lefrant, Jean-Yves, Mat Nor, Mohd Basri, Rello, Jordi, Seoane, Leonardo, Slavin, Monica A., Valkonen, Miia, Venditti, Mario, Wong, Wai Tat, Zeitlinger, Markus and Roger, Claire (2023). A protocol for an international, multicentre pharmacokinetic study for Screening Antifungal Exposure in Intensive Care Units: The SAFE-ICU study. Critical Care and Resuscitation, 25 (1), 1-5. doi: 10.1016/j.ccrj.2023.04.002 |
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2023 Journal Article Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae—authors’ responseSumi, Chandra Datta, Roberts, Jason A and Sime, Fekade B (2023). Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Klebsiella pneumoniae—authors’ response. Journal of Antimicrobial Chemotherapy, 78 (3), 854-857. doi: 10.1093/jac/dkad017 |
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2022 Journal Article Current and emerging treatment options for multidrug resistant Escherichia coli urosepsis: a reviewWalker, Mikaela M., Roberts, Jason A., Rogers, Benjamin A., Harris, Patrick N. A. and Sime, Fekade B. (2022). Current and emerging treatment options for multidrug resistant Escherichia coli urosepsis: a review. Antibiotics, 11 (12) 1821, 1-20. doi: 10.3390/antibiotics11121821 |
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2022 Journal Article Evaluation of fosfomycin-sulbactam combination therapy against carbapenem-resistant Acinetobacter baumannii isolates in a hollow-fibre infection modelMohd Sazlly Lim, Sazlyna, Heffernan, Aaron, Naicker, Saiyuri, Wallis, Steven, Roberts, Jason A. and Sime, Fekade Bruck (2022). Evaluation of fosfomycin-sulbactam combination therapy against carbapenem-resistant Acinetobacter baumannii isolates in a hollow-fibre infection model. Antibiotics, 11 (11) 1578, 1-11. doi: 10.3390/antibiotics11111578 |
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2022 Journal Article Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Escherichia coli clinical isolatesSumi, Chandra Datta, Heffernan, Aaron J., Naicker, Saiyuri, Cottrell, Kyra, Wallis, Steven C., Lipman, Jeffrey, Harris, Patrick N. A., Sime, Fekade B. and Roberts, Jason A. (2022). Pharmacodynamic evaluation of intermittent versus extended and continuous infusions of piperacillin/tazobactam in a hollow-fibre infection model against Escherichia coli clinical isolates. Journal of Antimicrobial Chemotherapy, 77 (11), 3026-3034. doi: 10.1093/jac/dkac273 |
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2022 Journal Article Pharmacodynamics of Piperacillin-Tazobactam/Amikacin Combination versus Meropenem against Extended-Spectrum β-Lactamase-Producing Escherichia coli in a Hollow Fiber Infection ModelIslam, Kamrul, Sime, Fekade B., Wallis, Steven C., Bauer, Michelle J., Naicker, Saiyuri, Won, Hayoung, Zowawi, Hosam M., Choudhury, Md Abu, Shirin, Tahmina, Habib, Zakir H., Harris, Patrick N. A., Flora, Meerjady S. and Roberts, Jason A. (2022). Pharmacodynamics of Piperacillin-Tazobactam/Amikacin Combination versus Meropenem against Extended-Spectrum β-Lactamase-Producing Escherichia coli in a Hollow Fiber Infection Model. Antimicrobial Agents and Chemotherapy, 66 (9), e0016222. doi: 10.1128/aac.00162-22 |
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2022 Journal Article Pharmacodynamic evaluation of piperacillin/tazobactam against extended-spectrum β-lactamase-producing versus non-producing Escherichia coli in a hollow-fibre infection modelIslam, Kamrul, Sime, Fekade B., Bauer, Michelle J., Forde, Brian M., Wallis, Steven C., Harris, Patrick, Naicker, Saiyuri, Shirin, Tahmina, Habib, Zakir H., Flora, Meerjady S. and Roberts, Jason A. (2022). Pharmacodynamic evaluation of piperacillin/tazobactam against extended-spectrum β-lactamase-producing versus non-producing Escherichia coli in a hollow-fibre infection model. International Journal of Antimicrobial Agents, 60 (2) 106623, 1-7. doi: 10.1016/j.ijantimicag.2022.106623 |
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2022 Journal Article Pharmacodynamic evaluation of piperacillin/tazobactam versus meropenem against extended-spectrum β-lactamase-producing and non-producing Escherichia coli clinical isolates in a hollow-fibre infection modelIslam, Kamrul, Sime, Fekade B., Wallis, Steven C., Bauer, Michelle J., Forde, Brian M., Harris, Patrick, Shirin, Tahmina, Habib, Zakir H., Flora, Meerjady S. and Roberts, Jason A. (2022). Pharmacodynamic evaluation of piperacillin/tazobactam versus meropenem against extended-spectrum β-lactamase-producing and non-producing Escherichia coli clinical isolates in a hollow-fibre infection model. Journal of Antimicrobial Chemotherapy, 77 (9), 2448-2455. doi: 10.1093/jac/dkac186 |
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2022 Journal Article Evaluation of the stability of temocillin in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy in accordance with the requirements of the UK NHS Yellow Cover DocumentSime, Fekade Bruck, Wallis, Steven, Jamieson, Conor, Hills, Tim, Gilchrist, Mark, Santillo, Mark, Seaton, R Andrew, Drummond, Felicity and Roberts, Jason (2022). Evaluation of the stability of temocillin in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy in accordance with the requirements of the UK NHS Yellow Cover Document. European Journal of Hospital Pharmacy, 30 (e1), ejhpharm-2022. doi: 10.1136/ejhpharm-2022-003286 |
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2022 Journal Article Multicenter population pharmacokinetic study of unbound ceftriaxone in critically ill patientsHeffernan, Aaron J., Sime, Fekade B., Kumta, Nilesh, Wallis, Steven C., McWhinney, Brett, Ungerer, Jacobus, Wong, Gloria, Joynt, Gavin M., Lipman, Jeffrey and Roberts, Jason A. (2022). Multicenter population pharmacokinetic study of unbound ceftriaxone in critically ill patients. Antimicrobial Agents and Chemotherapy, 66 (6), e0218921. doi: 10.1128/aac.02189-21 |
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2022 Journal Article Evaluating mono- and combination therapy of meropenem and amikacin against Pseudomonas aeruginosa bacteremia in the hollow-fiber infection modelAvent, Minyon L., McCarthy, Kate L., Sime, Fekade B., Naicker, Saiyuri, Heffernan, Aaron J., Wallis, Steven C., Paterson, David L. and Roberts, Jason A. (2022). Evaluating mono- and combination therapy of meropenem and amikacin against Pseudomonas aeruginosa bacteremia in the hollow-fiber infection model. Microbiology Spectrum, 10 (3), e0052522. doi: 10.1128/spectrum.00525-22 |
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2022 Journal Article Use of the hollow-fiber infection model to measure the effect of combination therapy of septic shock exposures of Meropenem and Ciprofloxacin against intermediate and resistant Pseudomonas aeruginosa clinical IsolatesKarabasevic, Natalija, Roberts, Jason A., Stronach, Luke, Naicker, Saiyuri, Wallis, Steven C., Sjövall, Fredrik and Sime, Fekade (2022). Use of the hollow-fiber infection model to measure the effect of combination therapy of septic shock exposures of Meropenem and Ciprofloxacin against intermediate and resistant Pseudomonas aeruginosa clinical Isolates. Antimicrobial Agents and Chemotherapy, 66 (5) e0214021, e0214021. doi: 10.1128/aac.02140-21 |
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2022 Journal Article Influence of PEGylated porous silicon nanoparticles on permeation and efflux of an orally administered antibioticRaza, A., Kamato, D., Sime, F.B., Roberts, J.A., Popat, A., Falconer, J.R. and Kumeria, T. (2022). Influence of PEGylated porous silicon nanoparticles on permeation and efflux of an orally administered antibiotic. Materials Today Advances, 13 100210, 100210. doi: 10.1016/j.mtadv.2022.100210 |
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2022 Journal Article Cefepime precision dosing tool: from standard to precise dose using nonparametric population pharmacokineticsAlshaer, Mohammad H., Goutelle, Sylvain, Santevecchi, Barbara, Shoulders, Bethany, Venugopalan, Veena, Cherabuddi, Kartikeya, Liu, Jiajun, Kiel, Patrick J., Roberts, Jason A., Sime, Fekade Bruck, Scheetz, Marc H., Neely, Michael N. and Peloquin, Charles A. (2022). Cefepime precision dosing tool: from standard to precise dose using nonparametric population pharmacokinetics. Antimicrobial Agents and Chemotherapy, 66 (2) e02046-21, 1-9. doi: 10.1128/aac.02046-21 |
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2022 Journal Article Pharmacodynamics of ceftriaxone for the treatment of methicillin‐susceptible Staphylococcus aureus: is it a viable treatment option?Heffernan, A.J., Sime, F.B., Lim, S. Mohd Sazlly, Adiraju, S., Wallis, S.C., Lipman, J., Grant, G.D. and Roberts, J.A. (2022). Pharmacodynamics of ceftriaxone for the treatment of methicillin‐susceptible Staphylococcus aureus: is it a viable treatment option?. International Journal of Antimicrobial Agents, 59 (3) 106537, 106537. doi: 10.1016/j.ijantimicag.2022.106537 |
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2021 Journal Article Pharmacodynamic evaluation of a single dose versus a 24-hour course of multiple doses of cefazolin for surgical prophylaxisHeffernan, Aaron, Alawie, Jowana, Wallis, Steven C., Naicker, Saiyuri, Adiraju, Santosh, Roberts, Jason A. and Sime, Fekade Bruck (2021). Pharmacodynamic evaluation of a single dose versus a 24-hour course of multiple doses of cefazolin for surgical prophylaxis. Antibiotics, 10 (5) 602, 602. doi: 10.3390/antibiotics10050602 |
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2021 Journal Article Epidemiology of extended-spectrum β-lactamase and metallo-β-lactamase-producing in South AsiaIslam, Kamrul, Heffernan, Aaron J., Naicker, Saiyuri, Henderson, Andrew, Chowdhury, Mohammed Abdul Hassan, Roberts, Jason A. and Sime, Fekade B. (2021). Epidemiology of extended-spectrum β-lactamase and metallo-β-lactamase-producing in South Asia. Future Microbiology, 16 (7) fmb-2020-0193, 521-535. doi: 10.2217/fmb-2020-0193 |
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2021 Journal Article Microfluidic assembly of pomegranate-like hierarchical microspheres for efflux regulation in oral drug deliveryRaza, Aun, Alavi, Seyed Ebrahim, Sime, Fekade Bruck, Han, Felicity Y., Roberts, Jason A., Popat, Amirali, Falconer, James R. and Kumeria, Tushar (2021). Microfluidic assembly of pomegranate-like hierarchical microspheres for efflux regulation in oral drug delivery. Acta Biomaterialia, 126, 277-290. doi: 10.1016/j.actbio.2021.03.042 |
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2021 Journal Article Semi-mechanistic PK/PD modelling of meropenem and sulbactam combination against carbapenem-resistant strains of Acinetobacter baumanniiMohd Sazlly Lim, Sazlyna, Heffernan, Aaron J., Zowawi, Hosam M., Roberts, Jason A. and Sime, Fekade B. (2021). Semi-mechanistic PK/PD modelling of meropenem and sulbactam combination against carbapenem-resistant strains of Acinetobacter baumannii. European Journal of Clinical Microbiology and Infectious Diseases, 40 (9), 1943-1952. doi: 10.1007/s10096-021-04252-z |
