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2018 Journal Article Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistanceBohlmann, Lisa, De Oliveira, David M. P., El-Deeb, Ibrahim M., Brazel, Erin B., Harbison-Price, Nichaela, Ong, Cheryl-lynn Y., Rivera-Hernandez, Tania, Ferguson, Scott A., Cork, Amanda J., Phan, Minh-Duy, Soderholm, Amelia T., Davies, Mark R., Nimmo, Graeme R., Dougan, Gordon, Schembri, Mark A., Cook, Gregory M., McEwan, Alastair G., von Itzstein, Mark, McDevitt, Christopher A. and Walker, Mark J. (2018). Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance. mBio, 9 (6) e02391-18. doi: 10.1128/mbio.02391-18 |
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2018 Journal Article Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistanceBohlmann, Lisa, De Oliveira, David M. P., El-Deeb, Ibrahim M., Brazel, Erin B., Harbison-Price, Nichaela, Ong, Cheryl-lynn Y., Rivera-Hernandez, Tania, Ferguson, Scott A., Cork, Amanda J., Phan, Minh-Duy, Soderholm, Amelia T., Davies, Mark R., Nimmo, Graeme R., Dougan, Gordon, Schembri, Mark A., Cook, Gregory M., McEwan, Alastair G., von Itzstein, Mark, McDevitt, Christopher A. and Walker, Mark J. (2018). Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance. mBio, 9 (6) e02391-18, 1-12. doi: 10.1128/mBio.02391-18 |
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2018 Journal Article Discovery of mcr-1-mediated colistin resistance in a highly virulent Escherichia coli lineageForde, Brian M., Zowawi, Hosam M., Harris, Patrick N. A., Roberts, Leah, Ibrahim, Emad, Shaikh, Nissar, Deshmukh, Anand, Sid Ahmed, Mazen A., Al Maslamani, Muna, Cottrell, Kyra, Trembizki, Ella, Sundac, Lana, Yu, Heidi H., Li, Jian, Schembri, Mark A., Whiley, David M., Paterson, David L. and Beatson, Scott A. (2018). Discovery of mcr-1-mediated colistin resistance in a highly virulent Escherichia coli lineage. mSphere, 3 (5) e00486-18. doi: 10.1128/msphere.00486-18 |
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2018 Journal Article Discovery of new genes involved in curli production by a uropathogenic Escherichia coli strain from the highly virulent O45:K1:H7 lineageNhu, Nguyen Thi Khanh, Phan, Minh-Duy, Peters, Kate M., Lo, Alvin W., Forde, Brian M., Min Chong, Teik, Yin, Wai-Fong, Chan, Kok-Gan, Chromek, Milan, Brauner, Annelie, Chapman, Matthew R., Beatson, Scott A. and Schembri, Mark A. (2018). Discovery of new genes involved in curli production by a uropathogenic Escherichia coli strain from the highly virulent O45:K1:H7 lineage. mBio, 9 (4) e01462-18. doi: 10.1128/mbio.01462-18 |
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2018 Journal Article Identification and characterization of a phase-variable element that regulates the autotransporter UpaE in uropathogenic Escherichia coliBattaglioli, E. J., Goh, K. G. K., Atruktsang, T. S., Schwartz, K., Schembri, M. A. and Welch, R. A. (2018). Identification and characterization of a phase-variable element that regulates the autotransporter UpaE in uropathogenic Escherichia coli. mBio, 9 (4) e01360-18. doi: 10.1128/mbio.01360-18 |
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2018 Journal Article A novel method of serum resistance by Escherichia coli that causes urosepsisCoggon, Carrie F., Jiang, Andrew, Goh, Kelvin G. K., Henderson, Ian R., Schembri, Mark A. and Wells, Timothy J. (2018). A novel method of serum resistance by Escherichia coli that causes urosepsis. mBio, 9 (3) e00920-18, e00920-18. doi: 10.1128/mbio.00920-18 |
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2018 Journal Article The urinary microbiome in patients with refractory urge incontinence and recurrent urinary tract infectionChen, Zhuoran, Phan, Minh-Duy, Bates, Lucy J., Peters, Kate M., Mukerjee, Chinmoy, Moore, Kate H. and Schembri, Mark A. (2018). The urinary microbiome in patients with refractory urge incontinence and recurrent urinary tract infection. International Urogynecology Journal, 29 (12), 1-8. doi: 10.1007/s00192-018-3679-2 |
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2018 Journal Article Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophagesMurthy, Ambika M. V., Phan, Minh-Duy, Peters, Kate M., Nhu, Nguyen Thi Khanh, Welch, Rodney A., Ulett, Glen C., Schembri, Mark A. and Sweet, Matthew J. (2018). Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages. Virulence, 9 (1), 1-32. doi: 10.1080/21505594.2018.1465786 |
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2018 Journal Article Molecular basis for the folding of β-helical autotransporter passenger domainsYuan, Xiaojun, Johnson, Matthew D., Zhang, Jing, Lo, Alvin W., Schembri, Mark A., Wijeyewickrema, Lakshmi C., Pike, Robert N., Huysmans, Gerard H. M., Henderson, Ian R. and Leyton, Denisse L. (2018). Molecular basis for the folding of β-helical autotransporter passenger domains. Nature Communications, 9 (1) 1395, 1395. doi: 10.1038/s41467-018-03593-2 |
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2018 Journal Article Intestinal colonization traits of pandemic multidrug-resistant Escherichia coli ST131Sarkar, Sohinee, Hutton, Melanie L., Vagenas, Dimitrios, Ruter, Rinaldo, Schüller, Stephanie, Lyras, Dena, Schembri, Mark A. and Totsika, Makrina (2018). Intestinal colonization traits of pandemic multidrug-resistant Escherichia coli ST131. The Journal of Infectious Diseases, 218 (6), 979-990. doi: 10.1093/infdis/jiy031 |
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2018 Journal Article Copper ions and coordination complexes as novel carbapenem adjuvantsDjoko, Karrera Y., Achard, Maud E. S., Phan, Minh-Duy, Lo, Alvin W., Miraula, Manfredi, Prombhul, Sasiprapa, Hancock, Steven J., Peters, Kate M., Sidjabat, Hanna E., Harris, Patrick N., Mitić, Nataša, Walsh, Timothy R., Anderson, Gregory J., Shafer, William M., Paterson, David L., Schenk, Gerhard, McEwan, Alastair G. and Schembri, Mark A. (2018). Copper ions and coordination complexes as novel carbapenem adjuvants. Antimicrobial Agents and Chemotherapy, 62 (2) e02280-17. doi: 10.1128/AAC.02280-17 |
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2018 Journal Article Bacterial pathogenesis and interleukin-17: interconnecting mechanisms of immune regulation, host genetics, and microbial virulence that influence severity of infectionChamoun, Michelle N., Blumenthal, Antje, Sullivan, Matthew J., Schembri, Mark A. and Ulett, Glen C. (2018). Bacterial pathogenesis and interleukin-17: interconnecting mechanisms of immune regulation, host genetics, and microbial virulence that influence severity of infection. Critical Reviews in Microbiology, 44 (4), 1-22. doi: 10.1080/1040841X.2018.1426556 |
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2018 Journal Article For when bacterial infections persist: toll-like receptor-inducible direct antimicrobial pathways in macrophagesStocks, Claudia J., Schembri, Mark A., Sweet, Matthew J. and Kapetanovic, Ronan (2018). For when bacterial infections persist: toll-like receptor-inducible direct antimicrobial pathways in macrophages. Journal of Leukocyte Biology, 103 (1), 35-51. doi: 10.1002/JLB.4RI0917-358R |
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2017 Journal Article Crystal structures of Staphylococcus aureus ketol-acid reductoisomerase in complex with two transition state analogs that have biocidal activityPatel, Khushboo, Teran, David, Zheng, Shan, Kandale, Ajit, Garcia, Mario, Lv, You, Schembri, Mark A, McGeary, Ross P, Schenk, Gerhard and Guddat, Luke William (2017). Crystal structures of Staphylococcus aureus ketol-acid reductoisomerase in complex with two transition state analogs that have biocidal activity. Chemistry- A European Journal, 23 (72), 18289-18295. doi: 10.1002/chem.201704481 |
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2017 Journal Article Whole genome analysis of cephalosporin-resistant Escherichia coli from bloodstream infections in Australia, New Zealand and Singapore: high prevalence of CMY-2 producers and ST131 carrying blaCTX-M-15 and blaCTX-M-27Harris, Patrick N. A., Ben Zakour, Nouri L., Roberts, Leah W., Wailan, Alexander M., Zowawi, Hosam M., Tambyah, Paul A., Lye, David C., Jureen, Roland, Lee, Tau H., Yin, Mo, Izharuddin, Ezlyn, Looke, David, Runnegar, Naomi, Rogers, Benjamin, Bhally, Hasan, Crowe, Amy, Schembri, Mark A., Beatson, Scott A. and Paterson, David L. (2017). Whole genome analysis of cephalosporin-resistant Escherichia coli from bloodstream infections in Australia, New Zealand and Singapore: high prevalence of CMY-2 producers and ST131 carrying blaCTX-M-15 and blaCTX-M-27. The Journal of Antimicrobial Chemotherapy, 73 (3), 634-642. doi: 10.1093/jac/dkx466 |
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2017 Journal Article Genome-wide discovery of genes required for capsule production by uropathogenic Escherichia coliGoh, Kelvin G. K., Phan, Minh-Duy, Forde, Brian M., Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, Ulett, Glen C., Sweet, Matthew J., Beatson, Scott A. and Schembri, Mark A. (2017). Genome-wide discovery of genes required for capsule production by uropathogenic Escherichia coli. MBio, 8 (5) e01558-17. doi: 10.1128/mBio.01558-17 |
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2017 Journal Article Modifications in the pmrB gene are the primary mechanism for the development of chromosomally encoded resistance to polymyxins in uropathogenic Escherichia coliPhan, Minh-Duy, Nhu, Nguyen Thi Khanh, Achard, Maud E. S., Forde, Brian M., Hong, Kar Wai, Chong, Teik Min, Yin, Wai-Fong, Chan, Kok-Gan, West, Nicholas P., Walker, Mark J., Paterson, David L., Beatson, Scott A. and Schembri, Mark A. (2017). Modifications in the pmrB gene are the primary mechanism for the development of chromosomally encoded resistance to polymyxins in uropathogenic Escherichia coli. Journal of Antimicrobial Chemotherapy, 72 (10), 2729-2736. doi: 10.1093/jac/dkx204 |
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2017 Journal Article YeeJ is an inverse autotransporter from Escherichia coli that binds to peptidoglycan and promotes biofilm formationMartinez-Gil, Marta, Goh, Kelvin G. K., Rackaityte, Elze, Sakamoto, Chizuko, Audrain, Bianca, Moriel, Danilo G., Totsika, Makrina, Ghigo, Jean-Marc, Schembri, Mark A. and Beloin, Christophe (2017). YeeJ is an inverse autotransporter from Escherichia coli that binds to peptidoglycan and promotes biofilm formation. Scientific Reports, 7 (1) 11326, 11326. doi: 10.1038/s41598-017-10902-0 |
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2017 Journal Article A shape-shifting redox foldase contributes to Proteus mirabilis copper resistanceFurlong, Emily J., Lo, Alvin W., Kurth, Fabian, Premkumar, Lakshmanane, Totsika, Makrina, Achard, Maud E. S., Halili, Maria A., Heras, Begona, Whitten, Andrew E., Choudhury, Hassanul G., Schembri, Mark A. and Martin, Jennifer L. (2017). A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance. Nature Communications, 8 (1) 16065, 16065. doi: 10.1038/ncomms16065 |
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2017 Journal Article Structure-function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G-proteinsLittler, Dene R., Ang, Sheng Y., Moriel, Danilo G., Kocan, Martina, Kleifeld, Oded, Johnson, Matthew D., Tran, Mai T., Paton, Adrienne W., Paton, James C., Summers, Roger J., Schembri, Mark A., Rossjohn, Jamie and Beddoe, Travis (2017). Structure-function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G-proteins. Journal of Biological Chemistry, 292 (36), 15143-15158. doi: 10.1074/jbc.M117.796094 |
