|
2024 Journal Article Enhancing the Intrinsic Antiplasmodial Activity and Improving the Stability and Selectivity of a Tunable Peptide Scaffold Derived from Human Platelet Factor 4Lawrence, Nicole, Handley, Thomas N. G., de Veer, Simon J., Harding, Maxim D., Andraszek, Alicja, Hall, Lachlan, Raven, Karoline D., Duffy, Sandra, Avery, Vicky M., Craik, David J., Malins, Lara R. and McMorran, Brendan J. (2024). Enhancing the Intrinsic Antiplasmodial Activity and Improving the Stability and Selectivity of a Tunable Peptide Scaffold Derived from Human Platelet Factor 4. ACS Infectious Diseases, 10 (8), 2899-2912. doi: 10.1021/acsinfecdis.4c00276 |
|
2024 Journal Article Display technologies for expanding the pharmaceutical applications of cyclotidesXie, Jing, Kan, Meng‐Wei, de Veer, Simon J., Wang, Conan and Craik, David J. (2024). Display technologies for expanding the pharmaceutical applications of cyclotides. Israel Journal of Chemistry, 64 (8-9) e202400010. doi: 10.1002/ijch.202400010 |
|
2024 Journal Article Nucleation of a key beta-turn promotes cyclotide oxidative foldingTian, Sixin, de Veer, Simon J., Durek, Thomas, Wang, Conan K. and Craik, David J. (2024). Nucleation of a key beta-turn promotes cyclotide oxidative folding. Journal of Biological Chemistry, 300 (4) 107125, 107125. doi: 10.1016/j.jbc.2024.107125 |
|
2024 Journal Article Tertiary amide bond formation by an engineered asparaginyl ligasede Veer, Simon J., Zhou, Yan, Durek, Thomas, Craik, David J. and Rehm, Fabian B. H. (2024). Tertiary amide bond formation by an engineered asparaginyl ligase. Chemical Science, 15 (14) 06352, 5248-5255. doi: 10.1039/d3sc06352f |
|
2022 Journal Article Engineering the cyclization loop of MCoTI-II generates targeted cyclotides that potently inhibit factor XIIaTian, Sixin, Durek, Thomas, Wang, Conan K., Zdenek, Christina N., Fry, Bryan G., Craik, David J. and de Veer, Simon J. (2022). Engineering the cyclization loop of MCoTI-II generates targeted cyclotides that potently inhibit factor XIIa. Journal of Medicinal Chemistry, 65 (23), 15698-15709. doi: 10.1021/acs.jmedchem.2c01080 |
|
2022 Journal Article Cystine knot peptides with tuneable activity and mechanismLi, Choi Yi, Rehm, Fabian B. H., Yap, Kuok, Zdenek, Christina N., Harding, Maxim D., Fry, Bryan G., Durek, Thomas, Craik, David J. and Veer, Simon J. (2022). Cystine knot peptides with tuneable activity and mechanism. Angewandte Chemie, 61 (19) e202200951, e202200951. doi: 10.1002/ange.202200951 |
|
2022 Journal Article Enzymatic C‐to‐C Protein LigationRehm, Fabian B. H., Tyler, Tristan J., Veer, Simon J., Craik, David J. and Durek, Thomas (2022). Enzymatic C‐to‐C Protein Ligation. Angewandte Chemie International Edition, 134 (11) e202116672, e202116672. doi: 10.1002/anie.202116672 |
|
2022 Journal Article Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation systemWu, Yue, Cui, Zhenling, Huang, Yen-Hua, de Veer, Simon J., Aralov, Andrey V., Guo, Zhong, Moradi, Shayli V., Hinton, Alexandra O., Deuis, Jennifer R., Guo, Shaodong, Chen, Kai-En, Collins, Brett M., Vetter, Irina, Herzig, Volker, Jones, Alun, Cooper, Matthew A., King, Glenn F., Craik, David J., Alexandrov, Kirill and Mureev, Sergey (2022). Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system. Nature Communications, 13 (1) 260, 260. doi: 10.1038/s41467-021-27854-9 |
|
2021 Journal Article Enzymatic C-terminal protein engineering with aminesRehm, Fabian B. H., Tyler, Tristan J., Yap, Kuok, de Veer, Simon J., Craik, David J. and Durek, Thomas (2021). Enzymatic C-terminal protein engineering with amines. Journal of the American Chemical Society, 143 (46) jacs.1c08976, 19498-19504. doi: 10.1021/jacs.1c08976 |
|
2021 Journal Article An ultrapotent and selective cyclic peptide inhibitor of human β-factor XIIa in a cyclotide scaffoldLiu, Wenyu, de Veer, Simon J., Huang, Yen-Hua, Sengoku, Toru, Okada, Chikako, Ogata, Kazuhiro, Zdenek, Christina N., Fry, Bryan G., Swedberg, Joakim E., Passioura, Toby, Craik, David J. and Suga, Hiroaki (2021). An ultrapotent and selective cyclic peptide inhibitor of human β-factor XIIa in a cyclotide scaffold. Journal of the American Chemical Society, 143 (44) jacs.1c07574, 18481-18489. doi: 10.1021/jacs.1c07574 |
|
2021 Journal Article Melanocortin 1 receptor agonists based on a bivalent, bicyclic peptide frameworkDurek, Thomas, Kaas, Quentin, White, Andrew M., Weidmann, Joachim, Fuaad, Abdullah Ahmad, Cheneval, Olivier, Schroeder, Christina I., de Veer, Simon J., Dellsén, Anita, Österlund, Torben, Larsson, Niklas, Knerr, Laurent, Bauer, Udo, Plowright, Alleyn T. and Craik, David J. (2021). Melanocortin 1 receptor agonists based on a bivalent, bicyclic peptide framework. Journal of Medicinal Chemistry, 64 (14) acs.jmedchem.1c00095, 9906-9915. doi: 10.1021/acs.jmedchem.1c00095 |
|
2021 Journal Article Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidasesYap, Kuok, Du, Junqiao, Rehm, Fabian B. H., Tang, Shyn Ric, Zhou, Yan, Xie, Jing, Wang, Conan K., de Veer, Simon J., Lua, Linda H. L., Durek, Thomas and Craik, David J. (2021). Yeast-based bioproduction of disulfide-rich peptides and their cyclization via asparaginyl endopeptidases. Nature Protocols, 16 (3), 1-23. doi: 10.1038/s41596-020-00483-0 |
|
2020 Journal Article Der Sonnenblumen‐Trypsin‐Inhibitor 1 (SFTI‐1) in der Chemie und BiologieVeer, Simon J., White, Andrew M. and Craik, David J. (2020). Der Sonnenblumen‐Trypsin‐Inhibitor 1 (SFTI‐1) in der Chemie und Biologie. Angewandte Chemie, 133 (15), 8128-8151. doi: 10.1002/ange.202006919 |
|
2020 Journal Article Sunflower trypsin inhibitor-1 (SFTI-1): sowing seeds in the fields of chemistry and biologyde Veer, Simon J., White, Andrew M. and Craik, David (2020). Sunflower trypsin inhibitor-1 (SFTI-1): sowing seeds in the fields of chemistry and biology. Angewandte Chemie (International Edition), 59 (15), 2-24. doi: 10.1002/anie.202006919 |
|
2020 Journal Article An environmentally sustainable biomimetic production of cyclic disulfide-rich peptidesYap, Kuok, Du, Junqiao, Looi, Fong Yang, Tang, Shyn Ric, de Veer, Simon J., Bony, Anuja R., Rehm, Fabian B. H., Xie, Jing, Chan, Lai Yue, Wang, Conan K., Adams, David J., Lua, Linda H. L., Durek, Thomas and Craik, David J. (2020). An environmentally sustainable biomimetic production of cyclic disulfide-rich peptides. Green Chemistry, 22 (15), 5002-5016. doi: 10.1039/d0gc01366h |
|
2020 Journal Article Inside Cover: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. Int. Ed. 28/2020)White, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas and Craik, David J. (2020). Inside Cover: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. Int. Ed. 28/2020). Angewandte Chemie International Edition, 59 (28), 11162-11162. doi: 10.1002/anie.202006713 |
|
2020 Journal Article Innentitelbild: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. 28/2020)White, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas and Craik, David J. (2020). Innentitelbild: Application and Structural Analysis of Triazole‐Bridged Disulfide Mimetics in Cyclic Peptides (Angew. Chem. 28/2020). Angewandte Chemie, 132 (28), 11258-11258. doi: 10.1002/ange.202006713 |
|
2020 Journal Article Application and structural analysis of triazole‐bridged disulfide mimetics in cyclic peptidesWhite, Andrew M., Veer, Simon J., Wu, Guojie, Harvey, Peta J., Yap, Kuok, King, Gordon J., Swedberg, Joakim E., Wang, Conan K., Law, Ruby H. P., Durek, Thomas and Craik, David J. (2020). Application and structural analysis of triazole‐bridged disulfide mimetics in cyclic peptides. Angewandte Chemie International Edition, 132 (28) anie.202003435, 11369-11373. doi: 10.1002/anie.202003435 |
|
2020 Journal Article Binding loop substitutions in the cyclic peptide SFTI-1 generate potent and selective chymase inhibitorsLi, Choi Yi, Yap, Kuok, Swedberg, Joakim E., Craik, David J. and de Veer, Simon J. (2020). Binding loop substitutions in the cyclic peptide SFTI-1 generate potent and selective chymase inhibitors. Journal of Medicinal Chemistry, 63 (2) acs.jmedchem.9b01811, 816-826. doi: 10.1021/acs.jmedchem.9b01811 |
|
2019 Journal Article Cyclotides: from structure to functionde Veer, Simon J., Kan, Meng-Wei and Craik, David J. (2019). Cyclotides: from structure to function. Chemical Reviews, 119 (24) acs.chemrev.9b00402, 12375-12421. doi: 10.1021/acs.chemrev.9b00402 |
