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2013

Journal Article

Cyclotides suppress human T-Lymphocyte proliferation by an interleukin 2-dependent mechanism

Gruendemann, Carsten, Thell, Kathrin, Lengen, Karin, Garcia-Kaeufer, Manuel, Huang, Yen-Hua, Huber, Roman, Craik, David J., Schabbauer, Gernot and Gruber, Christian W. (2013). Cyclotides suppress human T-Lymphocyte proliferation by an interleukin 2-dependent mechanism. Plos One, 8 (6) e68016, e68016.1-e68016.12. doi: 10.1371/journal.pone.0068016

Cyclotides suppress human T-Lymphocyte proliferation by an interleukin 2-dependent mechanism

2013

Journal Article

High-affinity cyclic peptide matriptase inhibitors

Quimbar, Pedro, Malik, Uru, Sommerhoff, Christian P., Kaas, Quentin, Chan, Lai Y., Huang, Yen-Hua, Grundhuber, Maresa, Dunse, Kerry, Craik, David J., Anderson, Marilyn A. and Daly, Norelle L. (2013). High-affinity cyclic peptide matriptase inhibitors. Journal of Biological Chemistry, 288 (19), 13885-13896. doi: 10.1074/jbc.M113.460030

High-affinity cyclic peptide matriptase inhibitors

2013

Journal Article

Cyclization of the antimicrobial peptide gomesin with native chemical ligation: influences on stability and bioactivity

Chan, Lai Yue, Zhang, Veronica M., Huang, Yen-hua, Waters, Norman C., Bansal, Paramjit S., Craik, David J. and Daly, Norelle L. (2013). Cyclization of the antimicrobial peptide gomesin with native chemical ligation: influences on stability and bioactivity. Chembiochem, 14 (5), 617-624. doi: 10.1002/cbic.201300034

Cyclization of the antimicrobial peptide gomesin with native chemical ligation: influences on stability and bioactivity

2013

Journal Article

Design and characterization of novel antimicrobial peptides, R-BP100 and RW-BP100, with activity against Gram-negative and Gram-positive bacteria

Torcato, Inês M., Huang, Yen-Hua, Franquelim, Henri G., Gaspar, Diana, Craik, David J., Castanho, Miguel A. R. B. and Henriques, Sonia Troeira (2013). Design and characterization of novel antimicrobial peptides, R-BP100 and RW-BP100, with activity against Gram-negative and Gram-positive bacteria. Biochimica et Biophysica Acta, 1828 (3), 944-955. doi: 10.1016/j.bbamem.2012.12.002

Design and characterization of novel antimicrobial peptides, R-BP100 and RW-BP100, with activity against Gram-negative and Gram-positive bacteria

2012

Journal Article

Phosphatidylethanolamine-binding is a conserved feature of cyclotide-membrane interactions

Henriques, Sonia Troeira, Huang, Yen-Hua, Castanho, Miguel A. R. B., Bagatolli, Luis A., Sonza, Secondo, Tachedjan, Gilda, Daly, Norelle L. and Craik, David J. (2012). Phosphatidylethanolamine-binding is a conserved feature of cyclotide-membrane interactions. Journal of Biological Chemistry, 287 (40), 33629-33643. doi: 10.1074/jbc.M112.372011

Phosphatidylethanolamine-binding is a conserved feature of cyclotide-membrane interactions

2011

Journal Article

Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities

Henriques, Sónia Troeira, Huang, Yen-Hua, Rosengren, K. Johan, Franquelim, Henri G., Carvalho, Filomena A., Johnson, Adam, Sonza, Secondo, Tachedjian, Gilda, Castanho, Miguel A. R. B., Daly, Norelle L. and Craik, David J. (2011). Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities. Journal of Biological Chemistry, 286 (27), 24231-24241. doi: 10.1074/jbc.M111.253393

Decoding the membrane activity of the cyclotide kalata B1: The importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities

2011

Journal Article

Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides

Cascales, Laura, Henriques, Sónia T., Kerr, Markus C., Huang, Yen-Hua, Sweet, Matthew J., Daly, Norelle L. and Craik, David J. (2011). Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides. Journal of Biological Chemistry, Epub ahead of print (42), 36932-36943. doi: 10.1074/jbc.M111.264424

Identification and characterization of a new family of cell penetrating peptides: Cyclic cell penetrating peptides

2010

Journal Article

Cyclotide interactions with the nematode external surface

Colgrave, Michelle L., Huang, Yen-Hua, Craik, David J. and Kotze, Andrew C. (2010). Cyclotide interactions with the nematode external surface. Antimicrobial Agents and Chemotherapy, 54 (5), 2160-2166. doi: 10.1128/AAC.01306-09

Cyclotide interactions with the nematode external surface

2010

Journal Article

Lysine-scanning mutagenesis reveals an amendable face of the cyclotide kalata B1 for the optimization of nematocidal activity

Huang, Yen-Hua (黃彥華), Colgrave, Michelle L., Clark, Richard J., Kotze, Andrew C. and Craik, David J. (2010). Lysine-scanning mutagenesis reveals an amendable face of the cyclotide kalata B1 for the optimization of nematocidal activity. Journal of Biological Chemistry, 285 (14), 10797-10805. doi: 10.1074/jbc.M109.089854

Lysine-scanning mutagenesis reveals an amendable face of the cyclotide kalata B1 for the optimization of nematocidal activity

2009

Journal Article

The Biological Activity of the Prototypic Cyclotide Kalata B1 Is Modulated by the Formation of Multimeric Pores

Huang, Y. H., Colgrave, M. L., Daly, N. L., Keleshian, A, Martinac, B and Craik, D. J. (2009). The Biological Activity of the Prototypic Cyclotide Kalata B1 Is Modulated by the Formation of Multimeric Pores. Journal of Biological Chemistry, 284 (31), 20699-20707. doi: 10.1074/jbc.M109.003384

The Biological Activity of the Prototypic Cyclotide Kalata B1 Is Modulated by the Formation of Multimeric Pores

2008

Journal Article

Cyclotides: Natural, Circular Plant Peptides that possess significant activity against Gastrointestinal nematode parasites of sheep

Colgrave, M. L., Kotze, A. C., Huang, Y., O'Grady, J., Simonsen, S. M. and Craik, D. J. (2008). Cyclotides: Natural, Circular Plant Peptides that possess significant activity against Gastrointestinal nematode parasites of sheep. Biochemistry, 47 (20), 5581-5589. doi: 10.1021/bi800223y

Cyclotides: Natural, Circular Plant Peptides that possess significant activity against Gastrointestinal nematode parasites of sheep