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2019

Journal Article

Aneuvis: web-based exploration of numerical chromosomal variation in single cells

Piqué, Daniel G., Andriani, Grasiella A., Maggi, Elaine, Zimmerman, Samuel E., Greally, John M., Montagna, Cristina and Mar, Jessica C. (2019). Aneuvis: web-based exploration of numerical chromosomal variation in single cells. BMC Bioinformatics, 20 (1) 336, 336. doi: 10.1186/s12859-019-2842-1

Aneuvis: web-based exploration of numerical chromosomal variation in single cells

2019

Journal Article

A comparison of survival analysis methods for cancer gene expression RNA-Sequencing data

Raman, Pichai, Zimmerman, Samuel, Rathi, Komal S., de Torrenté, Laurence, Sarmady, Mahdi, Wu, Chao, Leipzig, Jeremy, Taylor, Deanne M., Tozeren, Aydin and Mar, Jessica C. (2019). A comparison of survival analysis methods for cancer gene expression RNA-Sequencing data. Cancer Genetics, 235-236, 1-12. doi: 10.1016/j.cancergen.2019.04.004

A comparison of survival analysis methods for cancer gene expression RNA-Sequencing data

2019

Journal Article

The Pediatric Cell Atlas: defining the growth phase of human development at single-cell resolution

Taylor, Deanne M., Aronow, Bruce J., Tan, Kai, Bernt, Kathrin, Salomonis, Nathan, Greene, Casey S., Frolova, Alina, Henrickson, Sarah E., Wells, Andrew, Pei, Liming, Jaiswal, Jyoti K., Whitsett, Jeffrey, Hamilton, Kathryn E., MacParland, Sonya A., Kelsen, Judith, Heuckeroth, Robert O., Potter, S. Steven, Vella, Laura A., Terry, Natalie A., Ghanem, Louis R., Kennedy, Benjamin C., Helbig, Ingo, Sullivan, Kathleen E., Castelo-Soccio, Leslie, Kreigstein, Arnold, Herse, Florian, Nawijn, Martijn C., Koppelman, Gerard H., Haendel, Melissa ... White, Peter S. (2019). The Pediatric Cell Atlas: defining the growth phase of human development at single-cell resolution. Developmental Cell, 49 (1), 10-29. doi: 10.1016/j.devcel.2019.03.001

The Pediatric Cell Atlas: defining the growth phase of human development at single-cell resolution

2019

Journal Article

The rise of the distributions: why non-normality is important for understanding the transcriptome and beyond

Mar, Jessica C. (2019). The rise of the distributions: why non-normality is important for understanding the transcriptome and beyond. Biophysical Reviews, 11 (1), 89-94. doi: 10.1007/s12551-018-0494-4

The rise of the distributions: why non-normality is important for understanding the transcriptome and beyond

2019

Journal Article

Estrogen activates Alzheimer's disease genes

Ratnakumar, Abhirami, Zimmerman, Samuel E., Jordan, Bryen A. and Mar, Jessica C. (2019). Estrogen activates Alzheimer's disease genes. Alzheimer's and Dementia: Translational Research and Clinical Interventions, 5 (C), 906-917. doi: 10.1016/j.trci.2019.09.004

Estrogen activates Alzheimer's disease genes

2019

Journal Article

A novel approach to modelling transcriptional heterogeneity identifies the oncogene candidate CBX2 in invasive breast carcinoma

Piqué, Daniel G., Montagna, Cristina, Greally, John M. and Mar, Jessica C. (2019). A novel approach to modelling transcriptional heterogeneity identifies the oncogene candidate CBX2 in invasive breast carcinoma. British Journal of Cancer, 120 (7), 746-753. doi: 10.1038/s41416-019-0387-8

A novel approach to modelling transcriptional heterogeneity identifies the oncogene candidate CBX2 in invasive breast carcinoma

2018

Journal Article

Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow

Xu, Chunliang, Gao, Xin, Wei, Qiaozhi, Nakahara, Fumio, Zimmerman, Samuel E., Mar, Jessica and Frenette, Paul S. (2018). Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow. Nature Communications, 9 (1) 2449. doi: 10.1038/s41467-018-04726-3

Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow

2018

Journal Article

The majority of CD45- Ter119- CD31- bone marrow cell fraction is of hematopoietic origin and contains erythroid and lymphoid progenitors

Boulais, Philip E., Mizoguchi, Toshihide, Zimmerman, Samuel, Nakahara, Fumio, Vivie, Judith, Mar, Jessica C., van Oudenaarden, Alexander and Frenette, Paul S. (2018). The majority of CD45- Ter119- CD31- bone marrow cell fraction is of hematopoietic origin and contains erythroid and lymphoid progenitors. Immunity, 49 (4), 627-639. doi: 10.1016/j.immuni.2018.2018.08.019

The majority of CD45- Ter119- CD31- bone marrow cell fraction is of hematopoietic origin and contains erythroid and lymphoid progenitors

2018

Journal Article

Evaluating methods of inferring gene regulatory networks highlights their lack of performance for single cell gene expression data

Chen, Shuonan and Mar, Jessica C. (2018). Evaluating methods of inferring gene regulatory networks highlights their lack of performance for single cell gene expression data. BMC Bioinformatics, 19 (1) 232, 232. doi: 10.1186/s12859-018-2217-z

Evaluating methods of inferring gene regulatory networks highlights their lack of performance for single cell gene expression data

2018

Journal Article

Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older adults

Kulkarni, Ameya S., Brutsaert, Erika F., Anghel, Valentin, Zhang, Kehao, Bloomgarden, Noah, Pollak, Michael, Mar, Jessica C., Hawkins, Meredith, Crandall, Jill P. and Barzilai, Nir (2018). Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older adults. Aging Cell, 17 (2) e12723, e12723. doi: 10.1111/acel.12723

Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older adults

2017

Journal Article

Changes in gene expression variability reveal a stable synthetic lethal interaction network in BRCA2-ovarian cancers

Bueno, Raymund and Mar, Jessica C. (2017). Changes in gene expression variability reveal a stable synthetic lethal interaction network in BRCA2-ovarian cancers. Methods, 131, 74-82. doi: 10.1016/j.ymeth.2017.07.021

Changes in gene expression variability reveal a stable synthetic lethal interaction network in BRCA2-ovarian cancers

2017

Journal Article

pathVar: a new method for pathway-based interpretation of gene expression variability

de Torrente, Laurence, Zimmerman, Samuel, Taylor, Deanne, Hasegawa, Yu, Wells, Christine A. and Mar, Jessica C. (2017). pathVar: a new method for pathway-based interpretation of gene expression variability. PeerJ, 2017 (5) e3334, e3334. doi: 10.7717/peerj.3334

pathVar: a new method for pathway-based interpretation of gene expression variability

2016

Journal Article

Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance

Ito, Kyoko, Turcotte, Raphaël, Cui, Jinhua, Zimmerman, Samuel E., Pinho, Sandra, Mizoguchi, Toshihide, Arai, Fumio, Runnels, Judith M., Alt, Clemens, Teruya-Feldstein, Julie, Mar, Jessica C., Singh, Rajat, Suda, Toshio, Lin, Charles P., Frenette, Paul S. and Ito, Keisuke (2016). Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance. Science, 354 (6316), 1156-1160. doi: 10.1126/science.aaf5530

Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance

2016

Journal Article

Not just a colourful metaphor: modelling the landscape of cellular development using Hopfield networks

Taherian Fard, Atefeh, Srihari, Sriganesh, Mar, Jessica C. and Ragan, Mark A. (2016). Not just a colourful metaphor: modelling the landscape of cellular development using Hopfield networks. NPJ Systems Biology and Applications, 2 (1) 16001, 16001. doi: 10.1038/npjsba.2016.1

Not just a colourful metaphor: modelling the landscape of cellular development using Hopfield networks

2015

Journal Article

The constrained maximal expression level owing to haploidy shapes gene content on the mammalian X chromosome

Hurst, Laurence D., Ghanbarian, Avazeh T., Forrest, Alistair R. R., Huminiecki, Lukasz, Rehli, Michael, Baillie, J. Kenneth, de Hoon, Michiel J. L., Haberle, Vanja, Lassmann, Timo, Kulakovskiy, Ivan V., Lizio, Marina, Itoh, Masayoshi, Andersson, Robin, Mungall, Christopher J., Meehan, Terrence F., Schmeier, Sebastian, Bertin, Nicolas, Jorgensen, Mette, Dimont, Emmanuel, Arner, Erik, Schmidl, Christian, Schaefer, Ulf, Medvedeva, Yulia A., Plessy, Charles, Vitezic, Morana, Severin, Jessica, Semple, Colin A., Ishizu, Yuri, Young, Robert S. ... Hayashizaki, Yoshihide (2015). The constrained maximal expression level owing to haploidy shapes gene content on the mammalian X chromosome. PLoS Biology, 13 (12) e1002315, e1002315. doi: 10.1371/journal.pbio.1002315

The constrained maximal expression level owing to haploidy shapes gene content on the mammalian X chromosome

2015

Journal Article

Application of gene expression trajectories initiated from ErbB receptor activation highlights the dynamics of divergent promoter usage

Carbajo, Daniel, Magi, Shigeyuki, Itoh, Masayoshi, Kawaji, Hideya, Lassmann, Timo, Arner, Erik, Forrest, Alistair R. R., Carninci, Piero, Hayashizaki, Yoshihide, Daub, Carsten O., Okada-Hatakeyama, Mariko and Mar, Jessica C. (2015). Application of gene expression trajectories initiated from ErbB receptor activation highlights the dynamics of divergent promoter usage. Plos One, 10 (12) e0144176, e0144176. doi: 10.1371/journal.pone.0144176

Application of gene expression trajectories initiated from ErbB receptor activation highlights the dynamics of divergent promoter usage

2015

Journal Article

Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development

Hasegawa, Yu., Taylor, Deanne., Ovchinnikov, Dmitry A., Wolvetang, Ernst J., de Torrente, Laurence. and Mar, Jessica C. (2015). Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development. PLoS Genetics, 11 (8) e1005428, e1005428. doi: 10.1371/journal.pgen.1005428

Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development

2015

Journal Article

Corrigendum: Genome-wide characterization of the routes to pluripotency

Hussein, Samer M. I., Puri, Mira C., Tonge, Peter D., Benevento, Marco, Corso, Andrew J., Clancy, Jennifer L., Mosbergen, Rowland, Li, Mira, Lee, Dong-Sung, Cloonan, Nicole, Wood, David L. A., Munoz, Javier, Middleton, Robert, Korn, Othmar, Patel, Hardip R., White, Carl A., Shin, Jong-Yeon, Gauthier, Maely E., Le Cao, Kim-Anh, Kim, Jong-Il, Mar, Jessica C., Shakiba, Nika, Ritchie, William, Rasko, John E. J., Grimmond, Sean M., Zandstra, Peter W., Wells, Christine A., Preiss, Thomas, Seo, Jeong-Sun ... Nagy, Andras (2015). Corrigendum: Genome-wide characterization of the routes to pluripotency. Nature, 523 (7562), 626-626. doi: 10.1038/nature14606

Corrigendum: Genome-wide characterization of the routes to pluripotency

2015

Journal Article

Erratum: Divergent reprogramming routes lead to alternative stem-cell states (Nature (2014) 516 (192-197) DOI: 10.1038/nature14047)

Tonge, Peter D., Corso, Andrew J., Monetti, Claudio, Hussein, Samer M. I., Puri, Mira C., Michael, Iacovos P., Li, Mira, Lee, Dong-Sung, Mar, Jessica C., Cloonan, Nicole, Wood, David L., Gauthier, Maely E., Korn, Othmar, Clancy, Jennifer L., Preiss, Thomas, Grimmond, Sean M., Shin, Jong-Yeon, Seo, Jeong-Sun, Wells, Christine A., Rogers, Ian M. and Nagy, Andras (2015). Erratum: Divergent reprogramming routes lead to alternative stem-cell states (Nature (2014) 516 (192-197) DOI: 10.1038/nature14047). Nature, 523 (7562), 626-626. doi: 10.1038/nature14607

Erratum: Divergent reprogramming routes lead to alternative stem-cell states (Nature (2014) 516 (192-197) DOI: 10.1038/nature14047)

2015

Journal Article

Chromosome instability in diffuse large B cell lymphomas is suppressed by activation of the noncanonical NF-κB pathway

Ramachandiran, Sampath, Adon, Arsene, Guo, Xiangxue, Wang, Yi, Wang, Huichen, Chen, Zhengjia, Kowalski, Jeanne, Sunay, Ustun R., Young, Andrew N., Brown, Theresa, Mar, Jessica C., Du, Yuhong, Fu, Haian, Mann, Karen P., Natkunam, Yasodha, Boise, Lawrence H., Saavedra, Harold I., Lossos, Izidore S. and Bernal-Mizrachi, Leon (2015). Chromosome instability in diffuse large B cell lymphomas is suppressed by activation of the noncanonical NF-κB pathway. International Journal of Cancer, 136 (10), 2341-2351. doi: 10.1002/ijc.29301

Chromosome instability in diffuse large B cell lymphomas is suppressed by activation of the noncanonical NF-κB pathway