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2015

Journal Article

Centipede venom: Recent discoveries and current state of knowledge

Undheim, Eivind, Fry, Bryan and King, Glenn F (2015). Centipede venom: Recent discoveries and current state of knowledge. Toxins, 7 (3), 679-704. doi: 10.3390/toxins7030679

Centipede venom: Recent discoveries and current state of knowledge

2015

Journal Article

Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy (vol 47, pg 73, 2015)

Simons, Cas, Rash, Lachlan D., Crawford, Joanna, Ma, Linlin, Cristofori-Armstrong, Ben, Miller, David, Ru, Kelin, Baillie, Gregory J., Alanay, Yasemin, Jacquinet, Adeline, Debray, Franois-Guillaume, Verloes, Alain, Shen, Joseph, Yesil, Goezde, Guler, Serhat, Yuksel, Adnan, Cleary, John G., Grimmond, Sean M., McGaughran, Julie, King, Glenn F., Gabbett, Michael T. and Taft, Ryan J. (2015). Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy (vol 47, pg 73, 2015). Nature Genetics, 47 (3), 304-304. doi: 10.1038/ng0315-304b

Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy (vol 47, pg 73, 2015)

2015

Journal Article

Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy

Simons Cas, Rash, Lachlan D., Crawford, Joanna, Ma, Linlin, Cristofori-Armstrong, Ben, Miller, David, Ru, Kelin, Baillie, Gregory J., Alanay, Yasemin, Jacquinet, Adeline, Debray, François-Guillaume, Verloes, Alain, Shen, Joseph, Yesil, Gözde, Guler, Serhat, Yuksel, Adnan, Cleary, John G., Grimmond, Sean M., McGaughran, Julie, King, Glenn F., Gabbett, Michael T. and Taft, Ryan J. (2015). Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy. Nature Genetics, 47 (1), 73-77. doi: 10.1038/ng.3153

Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy

2015

Journal Article

Safety and Efficacy of Tumor-Targeted Interleukin 12 Gene Therapy in Treated and Non-Treated, Metastatic Lesions

Cutrera, Jeffry, King, Glenn, Jones, Pamela, Kicenuik, Kristin, Gumpel, Elias, Xia, Xueqing and Li, Shulin (2015). Safety and Efficacy of Tumor-Targeted Interleukin 12 Gene Therapy in Treated and Non-Treated, Metastatic Lesions. Current Gene Therapy, 15 (1), 44-54.

Safety and Efficacy of Tumor-Targeted Interleukin 12 Gene Therapy in Treated and Non-Treated, Metastatic Lesions

2015

Journal Article

From foe to friend: using animal toxins to investigate ion channel function

Kalia, Jeet, Milescu, Mirela, Salvatierra, Juan, Wagner, Jordan, Klint, Julie K., King, Glenn F., Olivera, Baldomero M. and Bosmans, Frank (2015). From foe to friend: using animal toxins to investigate ion channel function. Journal of Molecular Biology, 427 (1), 158-175. doi: 10.1016/j.jmb.2014.07.027

From foe to friend: using animal toxins to investigate ion channel function

2015

Journal Article

The cystine knot is responsible for the exceptional stability of the insecticidal spider toxin ω-Hexatoxin-Hv1a

Herzig, Volker and King, Glenn F. (2015). The cystine knot is responsible for the exceptional stability of the insecticidal spider toxin ω-Hexatoxin-Hv1a. Toxins, 7 (10), 4366-4380. doi: 10.3390/toxins7104366

The cystine knot is responsible for the exceptional stability of the insecticidal spider toxin ω-Hexatoxin-Hv1a

2014

Journal Article

Construction of a hypervirulent and specific mycoinsecticide for locust control

Fang, Weiguo, Lu, Hsiao-Ling, King, Glenn F and St. Leger, Raymond J. (2014). Construction of a hypervirulent and specific mycoinsecticide for locust control. Scientific Reports, 4 (1) 7345, 7345.1-7345.6. doi: 10.1038/srep07345

Construction of a hypervirulent and specific mycoinsecticide for locust control

2014

Journal Article

No gain, no pain: NaV1.7 as an analgesic target

King, Glenn F and Vetter, Irina (2014). No gain, no pain: NaV1.7 as an analgesic target. ACS Chemical Neuroscience, Articles ASAP (9), 749-751. doi: 10.1021/cn500171p

No gain, no pain: NaV1.7 as an analgesic target

2014

Journal Article

Clawing through evolution: toxin diversification and convergence in the ancient lineage Chilopoda (Centipedes)

Undheim, Eivind, Jones, Alun, Clauser, Karl R., Holland, John W., Pineda Gonzalez, Sandy, King, Glenn F and Bryan Fry (2014). Clawing through evolution: toxin diversification and convergence in the ancient lineage Chilopoda (Centipedes). Molecular Biology and Evolution, 31 (8), 2124-2148. doi: 10.1093/molbev/msu162

Clawing through evolution: toxin diversification and convergence in the ancient lineage Chilopoda (Centipedes)

2014

Journal Article

A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a

Bende, Niraj S., Dziemborowicz, Sławomir, Mobli, Mehdi, Herzig, Volker, Gilchrist, John, Wagner, Jordan, Nicholson, Graham M., King, Glenn F and Bosmans, Frank (2014). A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a. Nature Communications, 5 (1) 4350, 4350. doi: 10.1038/ncomms5350

A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a

2014

Journal Article

Isolation, synthesis and characterization of omega-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type CaV channels

Klint, Julie K., Berecki, Géza, Durek, Thomas, Mobli, Mehdi, Knapp, Oliver, King, Glenn F., Adams, David J., Alewood, Paul F. and Rash, Lachlan D. (2014). Isolation, synthesis and characterization of omega-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type CaV channels. Biochemical Pharmacology, 89 (2), 276-286. doi: 10.1016/j.bcp.2014.02.008

Isolation, synthesis and characterization of omega-TRTX-Cc1a, a novel tarantula venom peptide that selectively targets L-type CaV channels

2014

Journal Article

Multifunctional warheads: diversification of the toxin arsenal of centipedes via novel multidomain transcripts

Undheim, Eivind A. B., Sunagar, Kartik, Hamilton, Brett R., Jones, Alun, Venter, Deon J., Fry, Bryan G. and King, Glenn F. (2014). Multifunctional warheads: diversification of the toxin arsenal of centipedes via novel multidomain transcripts. Journal of Proteomics, 102, 1-10. doi: 10.1016/j.jprot.2014.02.024

Multifunctional warheads: diversification of the toxin arsenal of centipedes via novel multidomain transcripts

2014

Journal Article

Functional implications of large backbone amplitude motions of the glycoprotein 130-binding epitope of interleukin-6

Bobby, Romel, Robustelli, Paul, Kralicek, Andrew V., Mobli, Mehdi, King, Glenn F., Grotzinger, Joachim and Dingley, Andrew J. (2014). Functional implications of large backbone amplitude motions of the glycoprotein 130-binding epitope of interleukin-6. FEBS Journal, 281 (10), 2471-2483. doi: 10.1111/febs.12800

Functional implications of large backbone amplitude motions of the glycoprotein 130-binding epitope of interleukin-6

2014

Journal Article

Intraspecific venom variation in the medically significant Southern Pacific Rattlesnake (Crotalus oreganus helleri): biodiscovery, clinical and evolutionary implications

Sunagar, Kartik, Undheim, Eivind A. B., Scheib, Holger, Gren, Eric C. K., Cochran, Chip, Person, Carl E., Koludarov, Ivan, Kelln, Wayne, Hayes, William K., King, Glenn F., Antunes, Agosthino and Fry, Bryan Grieg (2014). Intraspecific venom variation in the medically significant Southern Pacific Rattlesnake (Crotalus oreganus helleri): biodiscovery, clinical and evolutionary implications. Journal of Proteomics, 99, 68-83. doi: 10.1016/j.jprot.2014.01.013

Intraspecific venom variation in the medically significant Southern Pacific Rattlesnake (Crotalus oreganus helleri): biodiscovery, clinical and evolutionary implications

2014

Journal Article

Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders

Pineda, Sandy S., Sollod, Brianna L., Wilson, David, Darling, Aaron, Sunagar, Kartik, Undheim, Eivind A. B., Kely, Laurence, Antunes, Agostinho, Fry, Bryan G. and King, Glenn F (2014). Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders. BMC Genomics, 15 (1) 177, 177.1-177.16. doi: 10.1186/1471-2164-15-177

Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders

2014

Journal Article

A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1–S4 gating domain

Gui, Junhong, Liu, Boyi, Cao, Guan, Lipchik, Andrew M., Perez, Minervo, Dekan, Zoltan, Mobli, Mehdi, Daly, Norelle L., Alewood, Paul F., Parker, Laurie L., King, Glenn F., Zhou, Yufeng, Jordt, Sven-Eric and Nitabach, Michael N. (2014). A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1–S4 gating domain. Current Biology, 24 (5), 473-483. doi: 10.1016/j.cub.2014.01.013

A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1–S4 gating domain

2014

Journal Article

Chemical synthesis, 3D structure and ASIC binding site of mambalgin-2

Schroeder, Christina I., Rash, Lachlan D., Vila-Farrés, Xavier, Rosengren, K. Johan, Mobli, Mehdi, King, Glenn F., Alewood, Paul F., Craik, David J. and Durek, Thomas (2014). Chemical synthesis, 3D structure and ASIC binding site of mambalgin-2. Angewandte Chemie International Edition, 53 (4), 1017-1020. doi: 10.1002/anie.201308898

Chemical synthesis, 3D structure and ASIC binding site of mambalgin-2

2014

Journal Article

Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2

Schroeder, Christina I., Rash, Lachlan D., Vila-Farrés, Xavier, Rosengren, K. Johan, Mobli, Mehdi, King, Glenn F., Alewood, Paul F., Craik, David J. and Durek, Thomas (2014). Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2. Angewandte Chemie, 126 (4), 1035-1038. doi: 10.1002/ange.201308898

Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2

2014

Journal Article

Methods for deployment of spider venom peptides as bioinsecticides

Herzig, Volker, Bende, Niraj S., Alam, Md. Shohidul, Tedford, H. William, Kennedy, Robert M. and King, Glenn F. (2014). Methods for deployment of spider venom peptides as bioinsecticides. Advances in Insect Physiology, 47, 389-411. doi: 10.1016/B978-0-12-800197-4.00008-7

Methods for deployment of spider venom peptides as bioinsecticides

2014

Journal Article

Spider venomics: implications for drug discovery

Pineda, Sandy S., Undheim, Eivind A. B., Rupasinghe, Darshani B., Ikonomopoulou, Maria P. and King, Glenn F. (2014). Spider venomics: implications for drug discovery. Future Medicinal Chemistry, 6 (15), 1699-1714. doi: 10.4155/FMC.14.103

Spider venomics: implications for drug discovery