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2018

Journal Article

Adoption of Lung Protective ventilation IN patients undergoing Emergency laparotomy: the ALPINE study. A prospective multicentre observational study

Watson, X., Chereshneva, M., Odor, P. M., Chis Ster, I., Pan-London Perioperative Audit and Research Network (PLAN), Cecconi, M., Johnston, C., Huddart, S., Woods, J., Hadi, N., Ali, S., Gill, P., Thorning, G., Boomers, O., Rope, T., Bartlett, R., Kuttler, A., O'Carroll-Kuehn, B., Dickinson, M., Lyness, C., Jha, R., Patel, S., Raj, A., Tanqueray, T., Cox, M., Khader, A., Vashisht, S., Liyanage, S., Ahmed, K. ... McHugh, B. (2018). Adoption of Lung Protective ventilation IN patients undergoing Emergency laparotomy: the ALPINE study. A prospective multicentre observational study. British Journal of Anaesthesia, 121 (4), 909-917. doi: 10.1016/j.bja.2018.04.048

Adoption of Lung Protective ventilation IN patients undergoing Emergency laparotomy: the ALPINE study. A prospective multicentre observational study

2018

Journal Article

A bright forecast for autoregulation monitoring?

Highton, David (2018). A bright forecast for autoregulation monitoring?. The Journal of Physiology, 596 (14), 2637-2638. doi: 10.1113/JP276290

A bright forecast for autoregulation monitoring?

2017

Journal Article

Pressure passivity of cerebral mitochondrial metabolism is associated with poor outcome following perinatal hypoxic ischemic brain injury

Mitra, Subhabrata, Bale, Gemma, Highton, David, Gunny, Roxanna, Uria-Avellanal, Cristina, Bainbridge, Alan, Sokolska, Magdalena, Price, David, Huertas-Ceballos, Angela, Kendall, Giles S., Meek, Judith, Tachtsidis, Ilias and Robertson, Nicola J. (2017). Pressure passivity of cerebral mitochondrial metabolism is associated with poor outcome following perinatal hypoxic ischemic brain injury. Journal of Cerebral Blood Flow and Metabolism, 39 (1), 118-130. doi: 10.1177/0271678X17733639

Pressure passivity of cerebral mitochondrial metabolism is associated with poor outcome following perinatal hypoxic ischemic brain injury

2017

Journal Article

Image reconstruction of oxidized cerebral cytochrome C oxidase changes from broadband near-infrared spectroscopy data

Brigadoi, Sabrina, Phan, Phong, Highton, David, Powell, Samuel, Cooper, Robert J., Hebden, Jeremy, Smith, Martin, Tachtsidis, Ilias, Elwell, Clare E. and Gibson, Adam P. (2017). Image reconstruction of oxidized cerebral cytochrome C oxidase changes from broadband near-infrared spectroscopy data. Neurophotonics, 4 (2) 021105, 021105. doi: 10.1117/1.NPh.4.2.021105

Image reconstruction of oxidized cerebral cytochrome C oxidase changes from broadband near-infrared spectroscopy data

2017

Journal Article

Pain Assessment in INTensive care (PAINT): an observational study of physician‐documented pain assessment in 45 intensive care units in the United Kingdom

Kemp, H. I., Bantel, C., Gordon, F., Brett, S. J., Laycock, H. C., PLAN and SEARCH Contributors and Highton, David (2017). Pain Assessment in INTensive care (PAINT): an observational study of physician‐documented pain assessment in 45 intensive care units in the United Kingdom. Anaesthesia, 72 (6), 737-748. doi: 10.1111/anae.13786

Pain Assessment in INTensive care (PAINT): an observational study of physician‐documented pain assessment in 45 intensive care units in the United Kingdom

2016

Journal Article

Multi-channel multi-distance broadband nearinfrared spectroscopy system to measure the spatial response of cellular oxygen metabolism and tissue oxygenation

Phan, Phong, Highton, David, Lai, Jonathan, Smith, Martin, Elwell, Clare and Tachtsidis, Ilias (2016). Multi-channel multi-distance broadband nearinfrared spectroscopy system to measure the spatial response of cellular oxygen metabolism and tissue oxygenation. Biomedical Optics Express, 7 (11) #268365, 4424-4440. doi: 10.1364/BOE.7.004424

Multi-channel multi-distance broadband nearinfrared spectroscopy system to measure the spatial response of cellular oxygen metabolism and tissue oxygenation

2016

Journal Article

Functional imaging of the human brain using a modular, fibre-less, high-density diffuse optical tomography system

Chitnis, Danial, Cooper, Robert J., Dempsey, Laura, Powell, Samuel, Quaggia, Simone, Highton, David, Elwell, Clare, Hebden, Jeremy C. and Everdell, Nicholas L. (2016). Functional imaging of the human brain using a modular, fibre-less, high-density diffuse optical tomography system. Biomedical Optics Express, 7 (10) #269685, 4275-4288. doi: 10.1364/BOE.7.004275

Functional imaging of the human brain using a modular, fibre-less, high-density diffuse optical tomography system

2016

Journal Article

Towards a wearable near infrared spectroscopic probe for monitoring concentrations of multiple chromophores in biological tissue in vivo

Chitnis, Danial, Airantzis, Dimitrios, Highton, David, Williams, Rhys, Phong Phan, Giagka, Vasiliki, Powell, Samuel, Cooper, Robert J., Tachtsidis, Ilias, Smith, Martin, Elwell, Clare E., Hebden, Jeremy C. and Everdell, Nicholas (2016). Towards a wearable near infrared spectroscopic probe for monitoring concentrations of multiple chromophores in biological tissue in vivo. Review of Scientific Instruments, 87 (6) 065112, 065112-1-065112-9. doi: 10.1063/1.4954722

Towards a wearable near infrared spectroscopic probe for monitoring concentrations of multiple chromophores in biological tissue in vivo

2016

Journal Article

Care of elderly patients: a prospective audit of the prevalence of hypotension and the use of BIS intraoperatively in 25 hospitals in London

Wickham, Alex, Highton, David, Martin, Daniel, The Pan London Perioperative Audit and Research Network, Anwar, Sibtain, Bampoe, Sohail, Bantel, Carsten, Gooneratne, Mevan, Hopkins, Philip, Hunningher, Annie, Johnston, Carolyn, Laycock, Helen, O'Carroll, James, Odor, Peter, Philips, Sioned, Visram, Anil and Wordsworth, Harriet (2016). Care of elderly patients: a prospective audit of the prevalence of hypotension and the use of BIS intraoperatively in 25 hospitals in London. Perioperative Medicine, 5 (1) 12. doi: 10.1186/s13741-016-0036-1

Care of elderly patients: a prospective audit of the prevalence of hypotension and the use of BIS intraoperatively in 25 hospitals in London

2016

Journal Article

Hyperoxia results in increased aerobic metabolism following acute brain injury

Ghosh, Arnab , Highton, David , Kolyva, Christina , Tachtsidis, Ilias , Elwell, Clare E. and Smith, Martin (2016). Hyperoxia results in increased aerobic metabolism following acute brain injury. Journal of Cerebral Blood Flow and Metabolism, 37 (8), 2910-2920. doi: 10.1177/0271678X16679171

Hyperoxia results in increased aerobic metabolism following acute brain injury

2015

Journal Article

Monitoring cerebral autoregulation after brain injury: multimodal assessment of cerebral slow-wave oscillations using near-infrared spectroscopy

Highton, David, Ghosh, Arnab, Tachtsidis, Ilias, Panovska-Griffiths, Jasmina, Elwell, Clare E. and Smith, Martin (2015). Monitoring cerebral autoregulation after brain injury: multimodal assessment of cerebral slow-wave oscillations using near-infrared spectroscopy. Anesthesia and Analgesia, 121 (1), 198-205. doi: 10.1213/ANE.0000000000000790

Monitoring cerebral autoregulation after brain injury: multimodal assessment of cerebral slow-wave oscillations using near-infrared spectroscopy

2015

Journal Article

BrainSignals revisited: simplifying a computational model of cerebral physiology

Caldwell, Matthew, Hapuarachchi, Tharindi, Highton, David, Elwell, Clare, Smith, Martin and Tachtsidis, Ilias (2015). BrainSignals revisited: simplifying a computational model of cerebral physiology. PLoS One, 10 (5) e0126695, e0126695. doi: 10.1371/journal.pone.0126695

BrainSignals revisited: simplifying a computational model of cerebral physiology

2014

Journal Article

Cytochrome c oxidase response to changes in cerebral oxygen delivery in the adult brain shows higher brain-specificity than haemoglobin

Kolyva, Christina, Ghosh, Arnab, Tachtsidis, Ilias, Highton, David, Cooper, Chris E., Smith, Martin and Elwell, Clare E. (2014). Cytochrome c oxidase response to changes in cerebral oxygen delivery in the adult brain shows higher brain-specificity than haemoglobin. NeuroImage, 85 (1), 234-244. doi: 10.1016/j.neuroimage.2013.05.070

Cytochrome c oxidase response to changes in cerebral oxygen delivery in the adult brain shows higher brain-specificity than haemoglobin

2013

Journal Article

Intensive care management of subarachnoid haemorrhage

Highton, David and Smith, Martin (2013). Intensive care management of subarachnoid haemorrhage. Journal of the Intensive Care Society, 14 (1), 28-35. doi: 10.1177/175114371301400108

Intensive care management of subarachnoid haemorrhage

2010

Journal Article

Noninvasive cerebral oximetry: Is there light at the end of the tunnel?

Highton, David, Elwell, Clare and Smith, Martin (2010). Noninvasive cerebral oximetry: Is there light at the end of the tunnel?. Current Opinion in Anesthesiology, 23 (5), 576-581. doi: 10.1097/ACO.0b013e32833e1536

Noninvasive cerebral oximetry: Is there light at the end of the tunnel?