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2014 Journal Article Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal painDantas De Araujo, Aline, Mobli, Mehdi, Castro, Joel, Harrington, Andrea M., Vetter, Irina, Dekan, Zoltan, Muttenthale, Markus, Wan, JingJing, Lewis, Richard J., King, Glenn F., Brierley, Stuart M. and Alewood, Paul F. (2014). Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain. Nature Communications, 5 (1) 3165, 3165.1-3165.12. doi: 10.1038/ncomms4165 |
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2014 Journal Article Measuring interactions of FERM domain-containing sorting nexin proteins with endosomal lipids and cargo moleculesGhai, Rajesh, Mobli, Mehdi and Collins, Brett M. (2014). Measuring interactions of FERM domain-containing sorting nexin proteins with endosomal lipids and cargo molecules. Methods in Enzymology, 534, 331-349. doi: 10.1016/B978-0-12-397926-1.00019-6 |
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2014 Journal Article Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping PharmacophoresJensen, Jonas E., Cristofori-Armstrong, Ben, Anangi, Raveendra, Rosengren, K. Johan, Lau, Carus H. Y., Mobli, Mehdi, Brust, Andreas, Alewood, Paul F., King, Glenn F. and Rash, Lachlan D. (2014). Understanding the Molecular Basis of Toxin Promiscuity: The Analgesic Sea Anemone Peptide APETx2 Interacts with Acid-Sensing Ion Channel 3 and hERG Channels via Overlapping Pharmacophores. Journal of Medicinal Chemistry, 57 (21), 9195-9203. doi: 10.1021/jm501400p |
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2013 Journal Article Do vicinal disulfide bridges mediate functionally important redox transformations in proteins?Dantas De Araujo, Aline, Herzig, Volker, Windley, Monique J., Dziemborowicz, Slawomir, Mobli, Mehdi, Nicholson, Graham M., Alewood, Paul F. and King, Glenn F. (2013). Do vicinal disulfide bridges mediate functionally important redox transformations in proteins?. Antioxidants and Redox Signaling, 19 (16), 1976-1980. doi: 10.1089/ars.2013.5365 |
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2013 Journal Article Vicinal disulfide constrained cyclic peptidomimetics: a turn mimetic scaffold targeting the norepinephrine transporterBrust, Andreas, Wang, Ching-I. A., Daly, Norelle L., Kennerly, Joe, Sadeghi, Mahsa, Christie, Macdonald J., Lewis, Richard J., Mobli, Mehdi and Alewood, Paul F. (2013). Vicinal disulfide constrained cyclic peptidomimetics: a turn mimetic scaffold targeting the norepinephrine transporter. Angewandte Chemie (International Edition), 52 (46), 12020-12023. doi: 10.1002/anie.201304660 |
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2013 Journal Article Isolation of an orally active insecticidal toxin from the venom of an Australian tarantulaHardy, Margaret C., Daly, Norelle L., Mobli, Mehdi, Morales, Rodrigo A. V. and King, Glenn F. (2013). Isolation of an orally active insecticidal toxin from the venom of an Australian tarantula. PLoS ONE, 8 (9), e73136.1-e73136.12. doi: 10.1371/journal.pone.0073136 |
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2013 Journal Article Solution structure and peptide binding of the PTB domain from the AIDA1 postsynaptic signaling scaffolding proteinSmirnova, Ekaterina, Shanbhag, Riya, Kurabi, Arwa, Mobli, Mehdi, Kwan, Jamie J. and Donaldson, Logan W. (2013). Solution structure and peptide binding of the PTB domain from the AIDA1 postsynaptic signaling scaffolding protein. PLoS ONE, 8 (6) e65605, e65605.1-e65605.8. doi: 10.1371/journal.pone.0065605 |
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2013 Journal Article Production of recombinant disulfide-rich venom peptides for structural and functional analysis via expression in the periplasm of E. coliKlint, Julie K., Senff, Sebastian, Saez, Natalie J., Seshadri, Radha, Lau, Ho Yee, Bende, Nira J., Undheim, Eivind A. B., Rash, Lachlan D., Mobli, Mehdi and King, Glenn F. (2013). Production of recombinant disulfide-rich venom peptides for structural and functional analysis via expression in the periplasm of E. coli. PLoS One, 8 (5) e63865, e63865.1-e63865.12. doi: 10.1371/journal.pone.0063865 |
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2013 Journal Article The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channelsBende, Niraj S., Kang, Eunji, Herzig, Volker, Bosmans, Frank, Nicholson, Graham M., Mobli, Mehdi and King, Glenn F. (2013). The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels. Biochemical Pharmacology, 85 (10), 1542-1554. doi: 10.1016/j.bcp.2013.02.030 |
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2012 Journal Article Cyclization of peptides by using selenolanthionine bridgesDantas de Araujo, Aline, Mobli, Mehdi, King, Glenn F. and Alewood, Paul F. (2012). Cyclization of peptides by using selenolanthionine bridges. Angewandte Chemie International Edition, 51 (41), 10298-10302. doi: 10.1002/anie.201204229 |
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2012 Journal Article Sparse sampling methods in multidimensional NMRMobli, Mehdi, Maciejewski, Mark W., Schuyler, Adam D., Stern, Alan S. and Hoch, Jeffrey C. (2012). Sparse sampling methods in multidimensional NMR. Physical Chemistry Chemical Physics, 14 (31), 10835-10843. doi: 10.1039/c2cp40174f |
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2012 Journal Article Functional expression in Escherichia coli of the disulfide-rich sea anemone peptide APETx2, a potent blocker of acid-sensing ion channel 3Anangi, Raveendra, Rash, Lachlan D., Mobli, Mehdi and King, Glenn F. (2012). Functional expression in Escherichia coli of the disulfide-rich sea anemone peptide APETx2, a potent blocker of acid-sensing ion channel 3. Marine Drugs, 10 (7), 1605-1618. doi: 10.3390/md10071605 |
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2012 Journal Article Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3Jensen, Jonas E., Mobli, Mehdi, Brust, Andreas, Alewood, Paul F., King, Glenn F. and Rash, Lachlan D. (2012). Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3. Marine Drugs, 10 (7), 1511-1527. doi: 10.3390/md10071511 |
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2012 Journal Article Insulin-like growth factor binding protein 2: NMR analysis and structural characterization of the N-terminal domainGalea, Charles A., Mobli, Mehdi, McNeil, Kerrie A., Mulhern, Terrence D., Wallace, John C., King, Glenn F., Forbes, Briony E. and Norton, Raymond S. (2012). Insulin-like growth factor binding protein 2: NMR analysis and structural characterization of the N-terminal domain. Biochimie, 94 (3), 608-616. doi: 10.1016/j.biochi.2011.09.012 |
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2011 Journal Article Site-specific pKa determination of selenocysteine residues in selenovasopressin using 77Se NMRMobli, Mehdi, Morgenstern, David, King, Glenn F., Alewood, Paul F. and Muttenthaler, Markus (2011). Site-specific pKa determination of selenocysteine residues in selenovasopressin using 77Se NMR. Angewandte Chemie (International Edition), 50 (50), 11952-11955. doi: 10.1002/anie.201104169 |
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2011 Journal Article A dynamic pharmacophore drives the interaction between psalmotoxin-1 and the putative drug target acid-sensing ion channel 1aSaez, Natalie J., Mobli, Mehdi, Bieri, Michael, Chassagnon, Irene R., Malde, Alpeshkumar K., Gamsjaeger, Roland, Mark, Alan E., Gooley, Paul R., Rash. Lachlan D. and King, Glenn F. (2011). A dynamic pharmacophore drives the interaction between psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a. Molecular Pharmacology, 80 (5), 796-808. doi: 10.1124/mol.111.072207 |
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2011 Journal Article Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPasesGhai, Rajesh, Mobli, Mehdi, Norwood, Suzanne J., Bugarcic, Andrea, Teasdale, Rohan D., King, Glenn F. and Collins, Brett M. (2011). Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPases. Proceedings of the National Academy of Sciences of the United States of America, 108 (19), 7763-7768. doi: 10.1073/pnas.1017110108 |
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2011 Journal Article Macromolecular NMR spectroscopy for the non-spectroscopist: Beyond macromolecular structure determinationBieri, Michael, Kwan, Ann H., Mobli, Mehdi, King, Glenn F., Mackay, Joel P. and Gooley, Paul R. (2011). Macromolecular NMR spectroscopy for the non-spectroscopist: Beyond macromolecular structure determination. Febs Journal, 278 (5), 704-715. doi: 10.1111/j.1742-4658.2011.08005.x |
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2011 Journal Article Macromolecular NMR spectroscopy for the non-spectroscopistKwan, Ann H., Mobli, Mehdi, Gooley, Paul R., King, Glenn F. and Mackay, Joel P. (2011). Macromolecular NMR spectroscopy for the non-spectroscopist. Febs Journal, 278 (5), 687-703. doi: 10.1111/j.1742-4658.2011.08004.x |
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2011 Journal Article The N-terminal tail of hERG contains an amphipathic alpha-helix that regulates channel deactivationNg, Chai Ann, Hunter, Mark J., Perry, Matthew D., Mobli, Mehdi, Ke, Ying, Kuchel, Philip W., King, Glenn F., Stock, Daniela and Vandenberg, Jamie I. (2011). The N-terminal tail of hERG contains an amphipathic alpha-helix that regulates channel deactivation. PLoS One, 6 (1) e16191, e16191.1-e16191.9. doi: 10.1371/journal.pone.0016191 |
