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2020

Journal Article

Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors

Roy, Edwige, Wong, Ho Yi, Villani, Rehan, Rouille, Thomas, Salik, Basit, Sim, Seen Ling, Murigneux, Valentine, Stark, Mitchell S., Fink, J. Lynn, Soyer, H. Peter, Walker, Graeme, Lyons, J. Guy, Saunders, Nicholas and Khosrotehrani, Kiarash (2020). Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors. Cell Reports, 31 (9) 107702, 107702. doi: 10.1016/j.celrep.2020.107702

Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors

2019

Journal Article

Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells

Lukowski, Samuel W., Patel, Jatin, Andersen, Stacey B., Sim, Seen-Ling, Wong, Ho Yi, Tay, Joshua, Winkler, Ingrid, Powell, Joseph E. and Khosrotehrani, Kiarash (2019). Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells. Cell Reports, 27 (9), 2748-2758. doi: 10.1016/j.celrep.2019.04.102

Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells

2019

Journal Article

Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis

Donovan, Prudence, Patel, Jatin, Dight, James, Wong, Ho Yi, Sim, Seen-Ling, Murigneux, Valentine, Francois, Mathias and Khosrotehrani, Kiarash (2019). Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis. Nature Communications, 10 (1) 18, 18. doi: 10.1038/s41467-018-07961-w

Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis

2018

Journal Article

Genetic variation in the MAPK/ERK pathway affects contact hypersensitivity responses

Legrand, Julien M. D., Roy, Edwige, Baz, Batoul, Mukhopadhyay, Pamela, Wong, Ho Yi, Ram, Ramesh, Morahan, Grant, Walker, Graeme and Khosrotehrani, Kiarash (2018). Genetic variation in the MAPK/ERK pathway affects contact hypersensitivity responses. Journal of Allergy and Clinical Immunology, 142 (3), 981-984.e7. doi: 10.1016/j.jaci.2018.04.028

Genetic variation in the MAPK/ERK pathway affects contact hypersensitivity responses

2016

Journal Article

Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling

Roy, Edwige, Neufeld, Zoltan, Cerone, Luca, Wong, Ho Yi, Hodgson, Samantha, Livet, Jean and Khosrotehrani, Kiarash (2016). Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling. EMBO Journal, 35 (24), 2658-2670. doi: 10.15252/embj.201693806

Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling

2013

Journal Article

Reduced Il17a expression distinguishes a Ly6c lo MHCIIhi macrophage population promoting wound healing

Rodero, Mathieu P., Hodgson, Samantha S., Hollier, Brett, Combadiere, Christophe and Khosrotehrani, Kiarash (2013). Reduced Il17a expression distinguishes a Ly6c lo MHCIIhi macrophage population promoting wound healing. Journal of Investigative Dermatology, 133 (3), 783-792. doi: 10.1038/jid.2012.368

Reduced Il17a expression distinguishes a Ly6c lo MHCIIhi macrophage population promoting wound healing

2011

Journal Article

Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease

Peyrin-Biroulet, Laurent, Khosrotehrani, Kiarash, Carrat, Fabrice, Bouvier, Anne-Marie, Chevaux, Jean-Baptiste, Simon, Tabassome, Carbonnel, Frank, Colombel, Jean-Frederic, Dupas, Jean-Louis, Godeberge, Philippe, Hugot, Jean-Pierre, Lemann, Marc, Nahon, Stephane, Sabate, Jean-Marc, Tucat, Gilbert, Beaugerie, Laurent and For the Cesame Study Group (2011). Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease. Gastroenterology, 141 (5), 1621-1628.e5. doi: 10.1053/j.gastro.2011.06.050

Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease

2025

Journal Article

Haematological cancers and skin cancer: statistics from the Netherlands

von Schuckmann, Lena A and Khosrotehrani, Kiarash (2025). Haematological cancers and skin cancer: statistics from the Netherlands. British Journal of Dermatology. doi: 10.1093/bjd/ljaf081

Haematological cancers and skin cancer: statistics from the Netherlands

2025

Journal Article

Immune Checkpoint Inhibitors in Field Cancerization and Keratinocyte Cancer Prevention

Cox, Charlotte, Brown, Susan, Walpole, Euan, Roy, Edwige, Dousset, Lea, Ladwa, Rahul and Khosrotehrani, Kiarash (2025). Immune Checkpoint Inhibitors in Field Cancerization and Keratinocyte Cancer Prevention. JAMA Dermatology, 161 (4). doi: 10.1001/jamadermatol.2024.5750

Immune Checkpoint Inhibitors in Field Cancerization and Keratinocyte Cancer Prevention

2025

Journal Article

Prognostic markers could extend adjuvant immunotherapy to high-risk Stage IB/IIA melanoma: a modelling study

Tan, Samuel X., Muller, Nicholas, Zhou, Chenhao, Walpole, Euan, Smithers, B. Mark, Whiteman, David C. and Khosrotehrani, Kiarash (2025). Prognostic markers could extend adjuvant immunotherapy to high-risk Stage IB/IIA melanoma: a modelling study. JAAD International, 18, 86-87. doi: 10.1016/j.jdin.2024.09.010

Prognostic markers could extend adjuvant immunotherapy to high-risk Stage IB/IIA melanoma: a modelling study

2025

Journal Article

Assessing spatial sequencing and imaging approaches to capture the molecular and pathological heterogeneity of archived cancer tissues

Vo, Tuan, Prakrithi, P., Jones, Kahli, Yoon, Sohye, Lam, Pui Yeng, Kao, Yung-Ching, Ma, Ning, Tan, Samuel X., Jin, Xinnan, Zhou, Chenhao, Crawford, Joanna, Walters, Shaun, Gupta, Ishaan, Soyer, Peter H., Khosrotehrani, Kiarash, Stark, Mitchell S. and Nguyen, Quan (2025). Assessing spatial sequencing and imaging approaches to capture the molecular and pathological heterogeneity of archived cancer tissues. Journal of Pathology, 265 (3), 274-288. doi: 10.1002/path.6383

Assessing spatial sequencing and imaging approaches to capture the molecular and pathological heterogeneity of archived cancer tissues

2025

Journal Article

Understanding the pathophysiology of Pseudomonas aeruginosa colonization as a guide for future treatment for chronic leg ulcers

Matheus, Gabriela Gonzalez, Chamoun, Michelle N., Khosrotehrani, Kiarash, Sivakumaran, Yogeesan and Wells, Timothy J. (2025). Understanding the pathophysiology of Pseudomonas aeruginosa colonization as a guide for future treatment for chronic leg ulcers. Burns and Trauma, 13 tkae083, tkae083. doi: 10.1093/burnst/tkae083

Understanding the pathophysiology of Pseudomonas aeruginosa colonization as a guide for future treatment for chronic leg ulcers

2025

Journal Article

The empowering influence of air-liquid interface culture on skin organoid hair follicle development

Sun, Jane, Ahmed, Imaan, Brown, Jason, Khosrotehrani, Kiarash and Shafiee, Abbas (2025). The empowering influence of air-liquid interface culture on skin organoid hair follicle development. Burns and Trauma, 13 tkae070, tkae070-13. doi: 10.1093/burnst/tkae070

The empowering influence of air-liquid interface culture on skin organoid hair follicle development

2025

Journal Article

Beta‐Blockers and Cutaneous Melanoma Outcomes: A Systematic Review and Random‐Effects Meta‐Analysis

Muller, Nicholas M., Tan, Samuel X., Vipulaguna, Nisal, Zhou, Chenhao, Hughes, Maria Celia B., Soyer, H. Peter, von Schuckmann, Lena and Khosrotehrani, Kiarash (2025). Beta‐Blockers and Cutaneous Melanoma Outcomes: A Systematic Review and Random‐Effects Meta‐Analysis. Pigment Cell & Melanoma Research, 38 (1) e13225, e13225-1. doi: 10.1111/pcmr.13225

Beta‐Blockers and Cutaneous Melanoma Outcomes: A Systematic Review and Random‐Effects Meta‐Analysis

2024

Journal Article

A new frontier in drug discovery for skin cancer through electronic medical records

Dousset, Lea and Khosrotehrani, Kiarash (2024). A new frontier in drug discovery for skin cancer through electronic medical records. British Journal of Dermatology, 192 (4) ljae489, 570-571. doi: 10.1093/bjd/ljae489

A new frontier in drug discovery for skin cancer through electronic medical records

2024

Journal Article

Trial protocol for SiroSkin: a randomised double-blind placebo-controlled trial of topical sirolimus in chemoprevention of facial squamous cell carcinomas in solid organ transplant recipients

Dousset, Lea, Chambers, Daniel C., Webster, Angela, Isbel, Nicole, Campbell, Scott, Duarte, Carla, Collins, Louisa, Damian, Diona, Tseng, Anne, Karlsen, Emma, Ilinsky, Olga Victoria, Brown, Susan, Schaider, Helmut, Soyer, H. Peter, Ospino, Daniel Ariza, Hogarth, Sam, Chong, Alvin H., Mar, Victoria, McKenzie, Scott, Gin, Douglas, Fernandez-Penas, Pablo, Kern, Johannes S., Loewe, Katja, Roy, Edwige, Herschtal, Alan and Khosrotehrani, Kiarash (2024). Trial protocol for SiroSkin: a randomised double-blind placebo-controlled trial of topical sirolimus in chemoprevention of facial squamous cell carcinomas in solid organ transplant recipients. Trials, 25 (1) 789. doi: 10.1186/s13063-024-08619-3

Trial protocol for SiroSkin: a randomised double-blind placebo-controlled trial of topical sirolimus in chemoprevention of facial squamous cell carcinomas in solid organ transplant recipients

2024

Journal Article

Consensus versus discordance in the classification of borderline melanocytic lesions between dermatopathologists and artificial intelligence: An Australian cohort study

Muller, Nicholas M., Rutjes, Chantal, Tan, Samuel X., Vipulaguna, Nisal, Oloruntoba, Ayooluwatomiwa, Nguyen, Toan, von Schuckmann, Lena, Betz‐Stablein, Brigid, Khosrotehrani, Kiarash, Ge, Zongyuan, Soyer, H. Peter and Katz, Ian (2024). Consensus versus discordance in the classification of borderline melanocytic lesions between dermatopathologists and artificial intelligence: An Australian cohort study. Journal of the European Academy of Dermatology and Venereology. doi: 10.1111/jdv.20412

Consensus versus discordance in the classification of borderline melanocytic lesions between dermatopathologists and artificial intelligence: An Australian cohort study

2024

Journal Article

Generating skin‐derived precursor‐like cells from human‐induced pluripotent stem cell‐derived skin organoids

Ahmed, Imaan A., Sun, Jane, Kong, Min Jie, Khosrotehrani, Kiarash and Shafiee, Abbas (2024). Generating skin‐derived precursor‐like cells from human‐induced pluripotent stem cell‐derived skin organoids. Experimental Dermatology, 33 (11) e70017, e70017. doi: 10.1111/exd.70017

Generating skin‐derived precursor‐like cells from human‐induced pluripotent stem cell‐derived skin organoids

2024

Journal Article

Dr. Kiarash Khosrotehrani

Khosrotehrani, Kiarash (2024). Dr. Kiarash Khosrotehrani. The Nishinihon Journal of Dermatology, 86 (5), 517-518. doi: 10.2336/nishinihonhifu.86.517

Dr. Kiarash Khosrotehrani

2024

Journal Article

A scalable, spin‐free approach to generate enhanced induced pluripotent stem cell–derived natural killer cells for cancer immunotherapy

Rossi, Gustavo R., Sun, Jane, Lin, Cheng‐Yu, Wong, Joshua K.M., Alim, Louisa, Lam, Pui Yeng, Khosrotehrani, Kiarash, Wolvetang, Ernst, Cheetham, Seth W., Derrick, Emily B., Amoako, Akwasi, Lehner, Christoph, Brooks, Andrew J., Beavis, Paul A. and Souza‐Fonseca‐Guimaraes, Fernando (2024). A scalable, spin‐free approach to generate enhanced induced pluripotent stem cell–derived natural killer cells for cancer immunotherapy. Immunology & Cell Biology, 102 (10), 1-11. doi: 10.1111/imcb.12820

A scalable, spin‐free approach to generate enhanced induced pluripotent stem cell–derived natural killer cells for cancer immunotherapy