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2025 Journal Article Immune Checkpoint Inhibitors in Field Cancerization and Keratinocyte Cancer PreventionCox, Charlotte, Brown, Susan, Walpole, Euan, Roy, Edwige, Dousset, Lea, Ladwa, Rahul and Khosrotehrani, Kiarash (2025). Immune Checkpoint Inhibitors in Field Cancerization and Keratinocyte Cancer Prevention. JAMA Dermatology, 161 (4), 383. doi: 10.1001/jamadermatol.2024.5750 |
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Featured 2024 Journal Article Automated scoring of tumour infiltrating lymphocytes informs risk of death from thin melanoma: a nested case-case studyTan, Samuel X., Aung, Thazin N., Claeson, Magdalena, Acs, Balazs, Zhou, Chenhao, Brown, Susan, Lambie, Duncan, Baade, Peter D., Pandeya, Nirmala, Soyer, H. Peter, Smithers, B. Mark, Whiteman, David C., Rimm, David L. and Khosrotehrani, Kiarash (2024). Automated scoring of tumour infiltrating lymphocytes informs risk of death from thin melanoma: a nested case-case study. Journal of the American Academy of Dermatology, 90 (1), 179-182. doi: 10.1016/j.jaad.2023.09.026 |
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2023 Journal Article Development of physiologically relevant skin organoids from human induced pluripotent stem cellsShafiee, Abbas, Sun, Jane, Ahmed, Imaan A., Phua, Felicia, Rossi, Gustavo R., Lin, Cheng‐Yu, Souza‐Fonseca‐Guimaraes, Fernando, Wolvetang, Ernst J., Brown, Jason and Khosrotehrani, Kiarash (2023). Development of physiologically relevant skin organoids from human induced pluripotent stem cells. Small, 20 (16) e2304879, 1-14. doi: 10.1002/smll.202304879 |
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2023 Journal Article Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapyWong, Ho Yi, Lee, Ruby C., Chong, Sharene, Kapadia, Stuti, Freeman, Michael, Murigneux, Valentine, Brown, Susan, Soyer, H. Peter, Roy, Edwige and Khosrotehrani, Kiarash (2023). Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy. Science Advances, 9 (19) eadf2384, 1-13. doi: 10.1126/sciadv.adf2384 |
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2021 Journal Article Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitorsZhao, Jilai, Patel, Jatin, Kaur, Simranpreet, Sim, Seen-Ling, Wong, Ho Yi, Styke, Cassandra, Hogan, Isabella, Kahler, Sam, Hamilton, Hamish, Wadlow, Racheal, Dight, James, Hashemi, Ghazaleh, Sormani, Laura, Roy, Edwige, Yoder, Mervin C., Francois, Mathias and Khosrotehrani, Kiarash (2021). Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitors. Nature Communications, 12 (1) 2564, 1-17. doi: 10.1038/s41467-021-22717-9 |
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2020 Journal Article Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal ProgenitorsRoy, Edwige, Wong, Ho Yi, Villani, Rehan, Rouille, Thomas, Salik, Basit, Sim, Seen Ling, Murigneux, Valentine, Stark, Mitchell S., Fink, J. Lynn, Soyer, H. Peter, Walker, Graeme, Lyons, J. Guy, Saunders, Nicholas and Khosrotehrani, Kiarash (2020). Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors. Cell Reports, 31 (9) 107702, 107702. doi: 10.1016/j.celrep.2020.107702 |
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2019 Journal Article Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cellsLukowski, Samuel W., Patel, Jatin, Andersen, Stacey B., Sim, Seen-Ling, Wong, Ho Yi, Tay, Joshua, Winkler, Ingrid, Powell, Joseph E. and Khosrotehrani, Kiarash (2019). Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells. Cell Reports, 27 (9), 2748-2758. doi: 10.1016/j.celrep.2019.04.102 |
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Featured 2019 Journal Article Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasisDonovan, Prudence, Patel, Jatin, Dight, James, Wong, Ho Yi, Sim, Seen-Ling, Murigneux, Valentine, Francois, Mathias and Khosrotehrani, Kiarash (2019). Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis. Nature Communications, 10 (1) 18, 18. doi: 10.1038/s41467-018-07961-w |
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2016 Journal Article Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cyclingRoy, Edwige, Neufeld, Zoltan, Cerone, Luca, Wong, Ho Yi, Hodgson, Samantha, Livet, Jean and Khosrotehrani, Kiarash (2016). Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling. EMBO Journal, 35 (24), 2658-2670. doi: 10.15252/embj.201693806 |
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2011 Journal Article Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel diseasePeyrin-Biroulet, Laurent, Khosrotehrani, Kiarash, Carrat, Fabrice, Bouvier, Anne-Marie, Chevaux, Jean-Baptiste, Simon, Tabassome, Carbonnel, Frank, Colombel, Jean-Frederic, Dupas, Jean-Louis, Godeberge, Philippe, Hugot, Jean-Pierre, Lemann, Marc, Nahon, Stephane, Sabate, Jean-Marc, Tucat, Gilbert, Beaugerie, Laurent and For the Cesame Study Group (2011). Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease. Gastroenterology, 141 (5), 1621-1628.e5. doi: 10.1053/j.gastro.2011.06.050 |
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2007 Journal Article Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cellsHuu, Sau Nguyen, Oster, Michele, Uzan, Serge, Chareyre, Fabrice, Aractingi, Selim and Khosrotehrani, Kiarash (2007). Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cells. Proceedings of the National Academy of Sciences of the United States of America, 104 (6), 1871-1876. doi: 10.1073/pnas.0606490104 |
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2004 Journal Article Transfer of fetal cells with multilineage potential to maternal tissueKhosrotehrani, Kiarash, Johnson, Kirby L., Cha, Dong Hyun, Salomon, Robert N. and Bianchi, Diana W. (2004). Transfer of fetal cells with multilineage potential to maternal tissue. Jama: Journal of The American Medical Association, 292 (1), 75-80. doi: 10.1001/jama.292.1.75 |
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2025 Journal Article Haematological cancers and skin cancer: statistics from the Netherlandsvon Schuckmann, Lena A and Khosrotehrani, Kiarash (2025). Haematological cancers and skin cancer: statistics from the Netherlands. British Journal of Dermatology. doi: 10.1093/bjd/ljaf081 |
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2025 Journal Article Prognostic markers could extend adjuvant immunotherapy to high-risk Stage IB/IIA melanoma: a modelling studyTan, Samuel X., Muller, Nicholas, Zhou, Chenhao, Walpole, Euan, Smithers, B. Mark, Whiteman, David C. and Khosrotehrani, Kiarash (2025). Prognostic markers could extend adjuvant immunotherapy to high-risk Stage IB/IIA melanoma: a modelling study. JAAD International, 18, 86-87. doi: 10.1016/j.jdin.2024.09.010 |
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2025 Journal Article Assessing spatial sequencing and imaging approaches to capture the molecular and pathological heterogeneity of archived cancer tissuesVo, Tuan, Prakrithi, P., Jones, Kahli, Yoon, Sohye, Lam, Pui Yeng, Kao, Yung-Ching, Ma, Ning, Tan, Samuel X., Jin, Xinnan, Zhou, Chenhao, Crawford, Joanna, Walters, Shaun, Gupta, Ishaan, Soyer, Peter H., Khosrotehrani, Kiarash, Stark, Mitchell S. and Nguyen, Quan (2025). Assessing spatial sequencing and imaging approaches to capture the molecular and pathological heterogeneity of archived cancer tissues. Journal of Pathology, 265 (3), 274-288. doi: 10.1002/path.6383 |
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2025 Journal Article Understanding the pathophysiology of Pseudomonas aeruginosa colonization as a guide for future treatment for chronic leg ulcersMatheus, Gabriela Gonzalez, Chamoun, Michelle N., Khosrotehrani, Kiarash, Sivakumaran, Yogeesan and Wells, Timothy J. (2025). Understanding the pathophysiology of Pseudomonas aeruginosa colonization as a guide for future treatment for chronic leg ulcers. Burns and Trauma, 13 tkae083, tkae083. doi: 10.1093/burnst/tkae083 |
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2025 Journal Article The empowering influence of air-liquid interface culture on skin organoid hair follicle developmentSun, Jane, Ahmed, Imaan, Brown, Jason, Khosrotehrani, Kiarash and Shafiee, Abbas (2025). The empowering influence of air-liquid interface culture on skin organoid hair follicle development. Burns and Trauma, 13 tkae070, tkae070-13. doi: 10.1093/burnst/tkae070 |
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2025 Journal Article Beta‐Blockers and Cutaneous Melanoma Outcomes: A Systematic Review and Random‐Effects Meta‐AnalysisMuller, Nicholas M., Tan, Samuel X., Vipulaguna, Nisal, Zhou, Chenhao, Hughes, Maria Celia B., Soyer, H. Peter, von Schuckmann, Lena and Khosrotehrani, Kiarash (2025). Beta‐Blockers and Cutaneous Melanoma Outcomes: A Systematic Review and Random‐Effects Meta‐Analysis. Pigment Cell & Melanoma Research, 38 (1) e13225, e13225-1. doi: 10.1111/pcmr.13225 |
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2025 Journal Article Dermatopathologist consensus is crucial for the development of artificial intelligence training data in dermatologyMuller, N., Tan, S., Rutjes, C., Katz, I., Khosrotehrani, K., Ge, Z. and Soyer, P. (2025). Dermatopathologist consensus is crucial for the development of artificial intelligence training data in dermatology. EJC Skin Cancer, 3 100472, 100472. doi: 10.1016/j.ejcskn.2025.100472 |
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2024 Journal Article A new frontier in drug discovery for skin cancer through electronic medical recordsDousset, Lea and Khosrotehrani, Kiarash (2024). A new frontier in drug discovery for skin cancer through electronic medical records. British Journal of Dermatology, 192 (4) ljae489, 570-571. doi: 10.1093/bjd/ljae489 |
