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2025

Journal Article

Immune checkpoint inhibitors in field cancerization and keratinocyte cancer prevention

Cox, Charlotte, Brown, Susan, Walpole, Euan, Roy, Edwige, Dousset, Lea, Ladwa, Rahul and Khosrotehrani, Kiarash (2025). Immune checkpoint inhibitors in field cancerization and keratinocyte cancer prevention. JAMA Dermatology, 161 (4), 383-390. doi: 10.1001/jamadermatol.2024.5750

Immune checkpoint inhibitors in field cancerization and keratinocyte cancer prevention

2024

Journal Article

Automated scoring of tumour infiltrating lymphocytes informs risk of death from thin melanoma: a nested case-case study

Tan, Samuel X., Aung, Thazin N., Claeson, Magdalena, Acs, Balazs, Zhou, Chenhao, Brown, Susan, Lambie, Duncan, Baade, Peter D., Pandeya, Nirmala, Soyer, H. Peter, Smithers, B. Mark, Whiteman, David C., Rimm, David L. and Khosrotehrani, Kiarash (2024). Automated scoring of tumour infiltrating lymphocytes informs risk of death from thin melanoma: a nested case-case study. Journal of the American Academy of Dermatology, 90 (1), 179-182. doi: 10.1016/j.jaad.2023.09.026

Automated scoring of tumour infiltrating lymphocytes informs risk of death from thin melanoma: a nested case-case study

2023

Journal Article

Development of physiologically relevant skin organoids from human induced pluripotent stem cells

Shafiee, Abbas, Sun, Jane, Ahmed, Imaan A., Phua, Felicia, Rossi, Gustavo R., Lin, Cheng‐Yu, Souza‐Fonseca‐Guimaraes, Fernando, Wolvetang, Ernst J., Brown, Jason and Khosrotehrani, Kiarash (2023). Development of physiologically relevant skin organoids from human induced pluripotent stem cells. Small, 20 (16) e2304879, 1-14. doi: 10.1002/smll.202304879

Development of physiologically relevant skin organoids from human induced pluripotent stem cells

2023

Journal Article

Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy

Wong, Ho Yi, Lee, Ruby C., Chong, Sharene, Kapadia, Stuti, Freeman, Michael, Murigneux, Valentine, Brown, Susan, Soyer, H. Peter, Roy, Edwige and Khosrotehrani, Kiarash (2023). Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy. Science Advances, 9 (19) eadf2384, 1-13. doi: 10.1126/sciadv.adf2384

Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy

2021

Journal Article

Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitors

Zhao, Jilai, Patel, Jatin, Kaur, Simranpreet, Sim, Seen-Ling, Wong, Ho Yi, Styke, Cassandra, Hogan, Isabella, Kahler, Sam, Hamilton, Hamish, Wadlow, Racheal, Dight, James, Hashemi, Ghazaleh, Sormani, Laura, Roy, Edwige, Yoder, Mervin C., Francois, Mathias and Khosrotehrani, Kiarash (2021). Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitors. Nature Communications, 12 (1) 2564, 1-17. doi: 10.1038/s41467-021-22717-9

Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitors

2020

Journal Article

Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors

Roy, Edwige, Wong, Ho Yi, Villani, Rehan, Rouille, Thomas, Salik, Basit, Sim, Seen Ling, Murigneux, Valentine, Stark, Mitchell S., Fink, J. Lynn, Soyer, H. Peter, Walker, Graeme, Lyons, J. Guy, Saunders, Nicholas and Khosrotehrani, Kiarash (2020). Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors. Cell Reports, 31 (9) 107702, 107702. doi: 10.1016/j.celrep.2020.107702

Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors

2019

Journal Article

Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells

Lukowski, Samuel W., Patel, Jatin, Andersen, Stacey B., Sim, Seen-Ling, Wong, Ho Yi, Tay, Joshua, Winkler, Ingrid, Powell, Joseph E. and Khosrotehrani, Kiarash (2019). Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells. Cell Reports, 27 (9), 2748-2758. doi: 10.1016/j.celrep.2019.04.102

Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells

2019

Journal Article

Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis

Donovan, Prudence, Patel, Jatin, Dight, James, Wong, Ho Yi, Sim, Seen-Ling, Murigneux, Valentine, Francois, Mathias and Khosrotehrani, Kiarash (2019). Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis. Nature Communications, 10 (1) 18, 18. doi: 10.1038/s41467-018-07961-w

Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis

2016

Journal Article

Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling

Roy, Edwige, Neufeld, Zoltan, Cerone, Luca, Wong, Ho Yi, Hodgson, Samantha, Livet, Jean and Khosrotehrani, Kiarash (2016). Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling. EMBO Journal, 35 (24), 2658-2670. doi: 10.15252/embj.201693806

Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling

2011

Journal Article

Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease

Peyrin-Biroulet, Laurent, Khosrotehrani, Kiarash, Carrat, Fabrice, Bouvier, Anne-Marie, Chevaux, Jean-Baptiste, Simon, Tabassome, Carbonnel, Frank, Colombel, Jean-Frederic, Dupas, Jean-Louis, Godeberge, Philippe, Hugot, Jean-Pierre, Lemann, Marc, Nahon, Stephane, Sabate, Jean-Marc, Tucat, Gilbert, Beaugerie, Laurent and For the Cesame Study Group (2011). Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease. Gastroenterology, 141 (5), 1621-1628.e5. doi: 10.1053/j.gastro.2011.06.050

Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease

2007

Journal Article

Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cells

Huu, Sau Nguyen, Oster, Michele, Uzan, Serge, Chareyre, Fabrice, Aractingi, Selim and Khosrotehrani, Kiarash (2007). Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cells. Proceedings of the National Academy of Sciences of the United States of America, 104 (6), 1871-1876. doi: 10.1073/pnas.0606490104

Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cells

2004

Journal Article

Transfer of fetal cells with multilineage potential to maternal tissue

Khosrotehrani, Kiarash, Johnson, Kirby L., Cha, Dong Hyun, Salomon, Robert N. and Bianchi, Diana W. (2004). Transfer of fetal cells with multilineage potential to maternal tissue. Jama: Journal of The American Medical Association, 292 (1), 75-80. doi: 10.1001/jama.292.1.75

Transfer of fetal cells with multilineage potential to maternal tissue

2026

Journal Article

Moderate neuroprotection of combination cell therapy in fetal growth restricted newborns at postnatal day 10

Chand, Kirat K, Beecher, Kate, Nano, Rachel, Sim, Seen-Ling, Sun, Jane, Stokes-Marshall, Peytn, Macfarlane, Lillian, Luff, John, Musco, Hannah, Colditz, Paul B, Khosrotehrani, Kiarash, Patel, Jatin and Wixey, Julie A (2026). Moderate neuroprotection of combination cell therapy in fetal growth restricted newborns at postnatal day 10. Stem Cells Translational Medicine, 15 (5) szag019. doi: 10.1093/stcltm/szag019

Moderate neuroprotection of combination cell therapy in fetal growth restricted newborns at postnatal day 10

2026

Journal Article

A tissue multiplexing approach to maximize spatial omics output from pathology specimens

Kao, Yung-Ching, Lee, Katie J., Zhou, Chenhao, Causer, Andrew, Oey, Harald, Khosrotehrani, Kiarash, O’Brien, Blake, Collins, Angus, Nguyen, Quan, Soyer, H. Peter and Stark, Mitchell S. (2026). A tissue multiplexing approach to maximize spatial omics output from pathology specimens. Frontiers in Medicine, 13 1749401, 13. doi: 10.3389/fmed.2026.1749401

A tissue multiplexing approach to maximize spatial omics output from pathology specimens

2026

Conference Publication

Precision diagnostics for early melanoma detection using spatial biology and AI guided image analysis

Kao, Yung-Ching, Tan, Samuel X., Tan, Xiao, Oey, Harald, Lee, Katie J., Vallius, Tuulia, Pelletier, Roxanne, Causer, Andrew, Zhou, Chenhao, Smit, Darren, O'Neill, Jade, Xiong, Albert, O'Brien, Blake, Collins, Angus, Sorger, Peter Karl, Soyer, H. Peter, Khosrotehrani, Kiarash, Nguyen, Quan and Stark, Mitchell S. (2026). Precision diagnostics for early melanoma detection using spatial biology and AI guided image analysis. AACR Annual Meeting, San Diego, CA United States, 17-22 April 2026. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2026-4021

Precision diagnostics for early melanoma detection using spatial biology and AI guided image analysis

2026

Journal Article

Second primary invasive cutaneous melanomas in Queensland over 4 decades

Youlden, Danny R., Atkinson, Victoria, Pinkham, Mark B., Barbour, Andrew, Xu, Wen, Khosrotehrani, Kiarash, Eastgate, Melissa, Lyle, Megan, Green, Solange, Nath, Artika, Negrello, Theresa, Cossio, Danica and Smithers, B. Mark (2026). Second primary invasive cutaneous melanomas in Queensland over 4 decades. Journal of Investigative Dermatology. doi: 10.1016/j.jid.2026.01.026

Second primary invasive cutaneous melanomas in Queensland over 4 decades

2026

Journal Article

Diagnosis of a case of scabies infestation with line-field confocal optical coherence tomography

Muller, Nicholas M., Tan, Samuel X., Nufer, Kaitlin, Darch, Katherine, van Rooij, Nicholas, Khosrotehrani, Kiarash, Soyer, H. Peter, Manahan, Melissa and Wu, Jason (2026). Diagnosis of a case of scabies infestation with line-field confocal optical coherence tomography. SKINdeep, 2 e183007. doi: 10.1553/skindeep.2026.183007

Diagnosis of a case of scabies infestation with line-field confocal optical coherence tomography

2026

Journal Article

Robust and interpretable prediction of gene markers and cell types from spatial transcriptomics data

Tan, Xiao, Mulay, Onkar, Xie, Jacky, MacDonald, Samual, Kim, Taehyun, Zhou, Chenhao, Xiong, Zherui, Tan, Samuel X., Ye, Nan, McCart Reed, Amy, Khosrotehrani, Kiarash, Roosta, Fred, Trzaskowski, Maciej, Simpson, Peter T. and Nguyen, Quan (2026). Robust and interpretable prediction of gene markers and cell types from spatial transcriptomics data. Nature Communications, 17 (1) 1781, 1781. doi: 10.1038/s41467-026-68487-0

Robust and interpretable prediction of gene markers and cell types from spatial transcriptomics data

2026

Journal Article

Development of digital algorithms for the early identification of rare clinical outcomes using electronic medical records: a case study of Hidradenitis suppurativa

Pham, Hai, McMeniman, Erin, Liu, Timothy, Eva, Jonaa, Khosrotehrani, Kiarash and Pole, Jason D. (2026). Development of digital algorithms for the early identification of rare clinical outcomes using electronic medical records: a case study of Hidradenitis suppurativa. Population Health Management, 29 (1), 50-55. doi: 10.1177/19427891251404892

Development of digital algorithms for the early identification of rare clinical outcomes using electronic medical records: a case study of Hidradenitis suppurativa

2026

Journal Article

A Prebiotic and Panthenol-Containing Repair Balm Improves Tolerability of Topical 5-Fluorouracil Field Therapy for Actinic Keratoses: A Randomised Controlled Trial

Tseng, Anne, Yu, Regina, Brown, Susan, Muller, Nicholas, Tan, Samuel X., Roy, Edwige, Nguyen, Suzanne, Kerob, Delphine and Khosrotehrani, Kiarash (2026). A Prebiotic and Panthenol-Containing Repair Balm Improves Tolerability of Topical 5-Fluorouracil Field Therapy for Actinic Keratoses: A Randomised Controlled Trial. Dermatology and Therapy. doi: 10.1007/s13555-026-01775-1

A Prebiotic and Panthenol-Containing Repair Balm Improves Tolerability of Topical 5-Fluorouracil Field Therapy for Actinic Keratoses: A Randomised Controlled Trial