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2020 Journal Article Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal ProgenitorsRoy, Edwige, Wong, Ho Yi, Villani, Rehan, Rouille, Thomas, Salik, Basit, Sim, Seen Ling, Murigneux, Valentine, Stark, Mitchell S., Fink, J. Lynn, Soyer, H. Peter, Walker, Graeme, Lyons, J. Guy, Saunders, Nicholas and Khosrotehrani, Kiarash (2020). Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors. Cell Reports, 31 (9) 107702, 107702. doi: 10.1016/j.celrep.2020.107702 |
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2019 Journal Article Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cellsLukowski, Samuel W., Patel, Jatin, Andersen, Stacey B., Sim, Seen-Ling, Wong, Ho Yi, Tay, Joshua, Winkler, Ingrid, Powell, Joseph E. and Khosrotehrani, Kiarash (2019). Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells. Cell Reports, 27 (9), 2748-2758. doi: 10.1016/j.celrep.2019.04.102 |
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2019 Journal Article Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasisDonovan, Prudence, Patel, Jatin, Dight, James, Wong, Ho Yi, Sim, Seen-Ling, Murigneux, Valentine, Francois, Mathias and Khosrotehrani, Kiarash (2019). Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis. Nature Communications, 10 (1) 18, 18. doi: 10.1038/s41467-018-07961-w |
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2018 Journal Article Genetic variation in the MAPK/ERK pathway affects contact hypersensitivity responsesLegrand, Julien M. D., Roy, Edwige, Baz, Batoul, Mukhopadhyay, Pamela, Wong, Ho Yi, Ram, Ramesh, Morahan, Grant, Walker, Graeme and Khosrotehrani, Kiarash (2018). Genetic variation in the MAPK/ERK pathway affects contact hypersensitivity responses. Journal of Allergy and Clinical Immunology, 142 (3), 981-984.e7. doi: 10.1016/j.jaci.2018.04.028 |
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2016 Journal Article Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cyclingRoy, Edwige, Neufeld, Zoltan, Cerone, Luca, Wong, Ho Yi, Hodgson, Samantha, Livet, Jean and Khosrotehrani, Kiarash (2016). Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling. EMBO Journal, 35 (24), 2658-2670. doi: 10.15252/embj.201693806 |
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2013 Journal Article Reduced Il17a expression distinguishes a Ly6c lo MHCIIhi macrophage population promoting wound healingRodero, Mathieu P., Hodgson, Samantha S., Hollier, Brett, Combadiere, Christophe and Khosrotehrani, Kiarash (2013). Reduced Il17a expression distinguishes a Ly6c lo MHCIIhi macrophage population promoting wound healing. Journal of Investigative Dermatology, 133 (3), 783-792. doi: 10.1038/jid.2012.368 |
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2011 Journal Article Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel diseasePeyrin-Biroulet, Laurent, Khosrotehrani, Kiarash, Carrat, Fabrice, Bouvier, Anne-Marie, Chevaux, Jean-Baptiste, Simon, Tabassome, Carbonnel, Frank, Colombel, Jean-Frederic, Dupas, Jean-Louis, Godeberge, Philippe, Hugot, Jean-Pierre, Lemann, Marc, Nahon, Stephane, Sabate, Jean-Marc, Tucat, Gilbert, Beaugerie, Laurent and For the Cesame Study Group (2011). Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease. Gastroenterology, 141 (5), 1621-1628.e5. doi: 10.1053/j.gastro.2011.06.050 |
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2025 Journal Article Haematological cancers and skin cancer: statistics from the Netherlandsvon Schuckmann, Lena A and Khosrotehrani, Kiarash (2025). Haematological cancers and skin cancer: statistics from the Netherlands. British Journal of Dermatology. doi: 10.1093/bjd/ljaf081 |
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2025 Journal Article Immune Checkpoint Inhibitors in Field Cancerization and Keratinocyte Cancer PreventionCox, Charlotte, Brown, Susan, Walpole, Euan, Roy, Edwige, Dousset, Lea, Ladwa, Rahul and Khosrotehrani, Kiarash (2025). Immune Checkpoint Inhibitors in Field Cancerization and Keratinocyte Cancer Prevention. JAMA Dermatology, 161 (4). doi: 10.1001/jamadermatol.2024.5750 |
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2025 Journal Article Prognostic markers could extend adjuvant immunotherapy to high-risk Stage IB/IIA melanoma: a modelling studyTan, Samuel X., Muller, Nicholas, Zhou, Chenhao, Walpole, Euan, Smithers, B. Mark, Whiteman, David C. and Khosrotehrani, Kiarash (2025). Prognostic markers could extend adjuvant immunotherapy to high-risk Stage IB/IIA melanoma: a modelling study. JAAD International, 18, 86-87. doi: 10.1016/j.jdin.2024.09.010 |
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2025 Journal Article Assessing spatial sequencing and imaging approaches to capture the molecular and pathological heterogeneity of archived cancer tissuesVo, Tuan, Prakrithi, P., Jones, Kahli, Yoon, Sohye, Lam, Pui Yeng, Kao, Yung-Ching, Ma, Ning, Tan, Samuel X., Jin, Xinnan, Zhou, Chenhao, Crawford, Joanna, Walters, Shaun, Gupta, Ishaan, Soyer, Peter H., Khosrotehrani, Kiarash, Stark, Mitchell S. and Nguyen, Quan (2025). Assessing spatial sequencing and imaging approaches to capture the molecular and pathological heterogeneity of archived cancer tissues. Journal of Pathology, 265 (3), 274-288. doi: 10.1002/path.6383 |
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2025 Journal Article Understanding the pathophysiology of Pseudomonas aeruginosa colonization as a guide for future treatment for chronic leg ulcersMatheus, Gabriela Gonzalez, Chamoun, Michelle N., Khosrotehrani, Kiarash, Sivakumaran, Yogeesan and Wells, Timothy J. (2025). Understanding the pathophysiology of Pseudomonas aeruginosa colonization as a guide for future treatment for chronic leg ulcers. Burns and Trauma, 13 tkae083, tkae083. doi: 10.1093/burnst/tkae083 |
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2025 Journal Article The empowering influence of air-liquid interface culture on skin organoid hair follicle developmentSun, Jane, Ahmed, Imaan, Brown, Jason, Khosrotehrani, Kiarash and Shafiee, Abbas (2025). The empowering influence of air-liquid interface culture on skin organoid hair follicle development. Burns and Trauma, 13 tkae070, tkae070-13. doi: 10.1093/burnst/tkae070 |
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2025 Journal Article Beta‐Blockers and Cutaneous Melanoma Outcomes: A Systematic Review and Random‐Effects Meta‐AnalysisMuller, Nicholas M., Tan, Samuel X., Vipulaguna, Nisal, Zhou, Chenhao, Hughes, Maria Celia B., Soyer, H. Peter, von Schuckmann, Lena and Khosrotehrani, Kiarash (2025). Beta‐Blockers and Cutaneous Melanoma Outcomes: A Systematic Review and Random‐Effects Meta‐Analysis. Pigment Cell & Melanoma Research, 38 (1) e13225, e13225-1. doi: 10.1111/pcmr.13225 |
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2024 Journal Article A new frontier in drug discovery for skin cancer through electronic medical recordsDousset, Lea and Khosrotehrani, Kiarash (2024). A new frontier in drug discovery for skin cancer through electronic medical records. British Journal of Dermatology, 192 (4) ljae489, 570-571. doi: 10.1093/bjd/ljae489 |
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2024 Conference Publication Pathologist consensus for diagnostic labels is crucial in the developement of artificial intelligence training data in dermatologyMuller, N.M., Tan, S.X., Rutjes, C., Khosrotehrani, K., von Schuckmann, L., Betz-Stablein, B. and Soyer, H. P. (2024). Pathologist consensus for diagnostic labels is crucial in the developement of artificial intelligence training data in dermatology. 53rd Annual ESDR Meeting, Lisbon, Portugal, 4-7 September 2024. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.jid.2024.10.431 |
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2024 Conference Publication Endothelial progenitors: Unlocking Tumor Vessel Normalization to Overcome Therapeutic Challenges in MelanomaSormani, L., Hashemi, G., Li, H., Zhou, C., Li, K., Chan, S., Tan, S.X., Nguyen, Q., Roy, E. and Khosrotehrani, K. (2024). Endothelial progenitors: Unlocking Tumor Vessel Normalization to Overcome Therapeutic Challenges in Melanoma. 53rd Annual ESDR Meeting, Lisbon, Portugal, 4-7 September 2024. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2024.10.391 |
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2024 Conference Publication 404 Spatial transcriptomic signatures in primary melanomas associated with sentinel node positivityMuller, N. M., Tan, S. X., Zhou, C., Kao, Y., Stark, M., Nguyen, Q. and Khosrotehrani, K. (2024). 404 Spatial transcriptomic signatures in primary melanomas associated with sentinel node positivity. 53rd Annual ESDR Meeting, 4-7 September 2024, Lisbon, Portugal. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2024.10.414 |
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2024 Conference Publication Systems genetics multi-trait analysis of mouse wound healing reveals novel trait interactions with candidate genes characterised by their epidermal expression nicheMuller, N.M., Tan, S.X., Galbraith, J., Zhou, C., Roy, E. and Khosrotehrani, K. (2024). Systems genetics multi-trait analysis of mouse wound healing reveals novel trait interactions with candidate genes characterised by their epidermal expression niche. 53rd Annual ESDR Meeting, Lisbon, Portugal, 4-7 September 2024. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2024.10.546 |
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2024 Journal Article Trial protocol for SiroSkin: a randomised double-blind placebo-controlled trial of topical sirolimus in chemoprevention of facial squamous cell carcinomas in solid organ transplant recipientsDousset, Lea, Chambers, Daniel C., Webster, Angela, Isbel, Nicole, Campbell, Scott, Duarte, Carla, Collins, Louisa, Damian, Diona, Tseng, Anne, Karlsen, Emma, Ilinsky, Olga Victoria, Brown, Susan, Schaider, Helmut, Soyer, H. Peter, Ospino, Daniel Ariza, Hogarth, Sam, Chong, Alvin H., Mar, Victoria, McKenzie, Scott, Gin, Douglas, Fernandez-Penas, Pablo, Kern, Johannes S., Loewe, Katja, Roy, Edwige, Herschtal, Alan and Khosrotehrani, Kiarash (2024). Trial protocol for SiroSkin: a randomised double-blind placebo-controlled trial of topical sirolimus in chemoprevention of facial squamous cell carcinomas in solid organ transplant recipients. Trials, 25 (1) 789. doi: 10.1186/s13063-024-08619-3 |
