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Featured 2025 Journal Article Immune checkpoint inhibitors in field cancerization and keratinocyte cancer preventionCox, Charlotte, Brown, Susan, Walpole, Euan, Roy, Edwige, Dousset, Lea, Ladwa, Rahul and Khosrotehrani, Kiarash (2025). Immune checkpoint inhibitors in field cancerization and keratinocyte cancer prevention. JAMA Dermatology, 161 (4), 383-390. doi: 10.1001/jamadermatol.2024.5750 |
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Featured 2024 Journal Article Automated scoring of tumour infiltrating lymphocytes informs risk of death from thin melanoma: a nested case-case studyTan, Samuel X., Aung, Thazin N., Claeson, Magdalena, Acs, Balazs, Zhou, Chenhao, Brown, Susan, Lambie, Duncan, Baade, Peter D., Pandeya, Nirmala, Soyer, H. Peter, Smithers, B. Mark, Whiteman, David C., Rimm, David L. and Khosrotehrani, Kiarash (2024). Automated scoring of tumour infiltrating lymphocytes informs risk of death from thin melanoma: a nested case-case study. Journal of the American Academy of Dermatology, 90 (1), 179-182. doi: 10.1016/j.jaad.2023.09.026 |
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2023 Journal Article Development of physiologically relevant skin organoids from human induced pluripotent stem cellsShafiee, Abbas, Sun, Jane, Ahmed, Imaan A., Phua, Felicia, Rossi, Gustavo R., Lin, Cheng‐Yu, Souza‐Fonseca‐Guimaraes, Fernando, Wolvetang, Ernst J., Brown, Jason and Khosrotehrani, Kiarash (2023). Development of physiologically relevant skin organoids from human induced pluripotent stem cells. Small, 20 (16) e2304879, 1-14. doi: 10.1002/smll.202304879 |
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Featured 2023 Journal Article Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapyWong, Ho Yi, Lee, Ruby C., Chong, Sharene, Kapadia, Stuti, Freeman, Michael, Murigneux, Valentine, Brown, Susan, Soyer, H. Peter, Roy, Edwige and Khosrotehrani, Kiarash (2023). Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy. Science Advances, 9 (19) eadf2384, 1-13. doi: 10.1126/sciadv.adf2384 |
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2021 Journal Article Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitorsZhao, Jilai, Patel, Jatin, Kaur, Simranpreet, Sim, Seen-Ling, Wong, Ho Yi, Styke, Cassandra, Hogan, Isabella, Kahler, Sam, Hamilton, Hamish, Wadlow, Racheal, Dight, James, Hashemi, Ghazaleh, Sormani, Laura, Roy, Edwige, Yoder, Mervin C., Francois, Mathias and Khosrotehrani, Kiarash (2021). Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitors. Nature Communications, 12 (1) 2564, 1-17. doi: 10.1038/s41467-021-22717-9 |
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Featured 2020 Journal Article Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal ProgenitorsRoy, Edwige, Wong, Ho Yi, Villani, Rehan, Rouille, Thomas, Salik, Basit, Sim, Seen Ling, Murigneux, Valentine, Stark, Mitchell S., Fink, J. Lynn, Soyer, H. Peter, Walker, Graeme, Lyons, J. Guy, Saunders, Nicholas and Khosrotehrani, Kiarash (2020). Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors. Cell Reports, 31 (9) 107702, 107702. doi: 10.1016/j.celrep.2020.107702 |
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Featured 2019 Journal Article Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cellsLukowski, Samuel W., Patel, Jatin, Andersen, Stacey B., Sim, Seen-Ling, Wong, Ho Yi, Tay, Joshua, Winkler, Ingrid, Powell, Joseph E. and Khosrotehrani, Kiarash (2019). Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells. Cell Reports, 27 (9), 2748-2758. doi: 10.1016/j.celrep.2019.04.102 |
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Featured 2019 Journal Article Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasisDonovan, Prudence, Patel, Jatin, Dight, James, Wong, Ho Yi, Sim, Seen-Ling, Murigneux, Valentine, Francois, Mathias and Khosrotehrani, Kiarash (2019). Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis. Nature Communications, 10 (1) 18, 18. doi: 10.1038/s41467-018-07961-w |
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Featured 2016 Journal Article Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cyclingRoy, Edwige, Neufeld, Zoltan, Cerone, Luca, Wong, Ho Yi, Hodgson, Samantha, Livet, Jean and Khosrotehrani, Kiarash (2016). Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling. EMBO Journal, 35 (24), 2658-2670. doi: 10.15252/embj.201693806 |
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Featured 2011 Journal Article Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel diseasePeyrin-Biroulet, Laurent, Khosrotehrani, Kiarash, Carrat, Fabrice, Bouvier, Anne-Marie, Chevaux, Jean-Baptiste, Simon, Tabassome, Carbonnel, Frank, Colombel, Jean-Frederic, Dupas, Jean-Louis, Godeberge, Philippe, Hugot, Jean-Pierre, Lemann, Marc, Nahon, Stephane, Sabate, Jean-Marc, Tucat, Gilbert, Beaugerie, Laurent and For the Cesame Study Group (2011). Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease. Gastroenterology, 141 (5), 1621-1628.e5. doi: 10.1053/j.gastro.2011.06.050 |
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Featured 2007 Journal Article Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cellsHuu, Sau Nguyen, Oster, Michele, Uzan, Serge, Chareyre, Fabrice, Aractingi, Selim and Khosrotehrani, Kiarash (2007). Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cells. Proceedings of the National Academy of Sciences of the United States of America, 104 (6), 1871-1876. doi: 10.1073/pnas.0606490104 |
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Featured 2004 Journal Article Transfer of fetal cells with multilineage potential to maternal tissueKhosrotehrani, Kiarash, Johnson, Kirby L., Cha, Dong Hyun, Salomon, Robert N. and Bianchi, Diana W. (2004). Transfer of fetal cells with multilineage potential to maternal tissue. Jama: Journal of The American Medical Association, 292 (1), 75-80. doi: 10.1001/jama.292.1.75 |
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2026 Conference Publication Functional microbiome differences underlie wound healing outcomesMatheus, Gabriela Gonzalez, Lim, Kai, Sivakumaran, Yogeesan, Khosrotehrani, Kiarash and Timothy, Wells (2026). Functional microbiome differences underlie wound healing outcomes. HOBOKEN: WILEY. |
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2026 Journal Article Rapid-access oncodermatology reduces systemic corticosteroid use and supports continuation of anticancer therapy after treatment-related cutaneous toxicityLiu, Yuyang, Tan, Samuel X., Muller, Nicholas M., Shen, Xiaohua, Lee, Celine, Lau, Yit Nah, Atkinson, Victoria, Ladwa, Rahul, Karlsen, Emma-Anne and Khosrotehrani, Kiarash (2026). Rapid-access oncodermatology reduces systemic corticosteroid use and supports continuation of anticancer therapy after treatment-related cutaneous toxicity. JAAD International. doi: 10.1016/j.jdin.2026.04.020 |
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2026 Journal Article A prebiotic and panthenol-containing repair balm improves tolerability of topical 5-fluorouracil field therapy for actinic keratoses: a randomised controlled trialTseng, Anne, Yu, Regina, Brown, Susan, Muller, Nicholas, Tan, Samuel X., Roy, Edwige, Nguyen, Suzanne, Kerob, Delphine and Khosrotehrani, Kiarash (2026). A prebiotic and panthenol-containing repair balm improves tolerability of topical 5-fluorouracil field therapy for actinic keratoses: a randomised controlled trial. Dermatology and Therapy. doi: 10.1007/s13555-026-01775-1 |
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2026 Journal Article Moderate neuroprotection of combination cell therapy in fetal growth restricted newborns at postnatal day 10Chand, Kirat K., Beecher, Kate, Nano, Rachel, Sim, Seen-Ling, Sun, Jane, Stokes-Marshall, Peytn, Macfarlane, Lillian, Luff, John, Musco, Hannah, Colditz, Paul B., Khosrotehrani, Kiarash, Patel, Jatin and Wixey, Julie A (2026). Moderate neuroprotection of combination cell therapy in fetal growth restricted newborns at postnatal day 10. Stem Cells Translational Medicine, 15 (5) szag019. doi: 10.1093/stcltm/szag019 |
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2026 Conference Publication H3K27ac-HiChIP variant-to-gene mapping confirms the importance of cancer drivers and oncogenic signaling pathways in melanoma riskThakur, Rohit, Jayasinghe, G. J. M. Shanika R., Xu, Mai, Bui-Raborn, Linh, Shi, Jianxin, Dutta, Diptavo, Hoang, Phuc H., Seviiri, Mathias, Amos, Christopher I., Bakshi, Andrew, Cust, Anne E., Demenais, Florence, Duffy, David L., Fritsche, Lars G., Han, Jiali, Hayward, Nicholas K., Khosrotehrani, Kiarash, Kumar, Rajiv, Thompson, John F., MacGregor, Stuart, Renteria, Miguel, Smelser, Diane T., Ward, Sarah V., Fargnoli, Maria Concetta, Ghiorzo, Paola, Goldstein, Alisa M., Menin, Chiara, Millan-Esteban, David, Nagore, Eduardo ... Brown, Kevin M. (2026). H3K27ac-HiChIP variant-to-gene mapping confirms the importance of cancer drivers and oncogenic signaling pathways in melanoma risk. AACR Annual Meeting, San Diego Ca, Apr 17-22, 2026. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.AM2026-LB384 |
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2026 Journal Article A tissue multiplexing approach to maximize spatial omics output from pathology specimensKao, Yung-Ching, Lee, Katie J., Zhou, Chenhao, Causer, Andrew, Oey, Harald, Khosrotehrani, Kiarash, O’Brien, Blake, Collins, Angus, Nguyen, Quan, Soyer, H. Peter and Stark, Mitchell S. (2026). A tissue multiplexing approach to maximize spatial omics output from pathology specimens. Frontiers in Medicine, 13 1749401, 13. doi: 10.3389/fmed.2026.1749401 |
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2026 Conference Publication Precision diagnostics for early melanoma detection using spatial biology and AI guided image analysisKao, Yung-Ching, Tan, Samuel X., Tan, Xiao, Oey, Harald, Lee, Katie J., Vallius, Tuulia, Pelletier, Roxanne, Causer, Andrew, Zhou, Chenhao, Smit, Darren, O'Neill, Jade, Xiong, Albert, O'Brien, Blake, Collins, Angus, Sorger, Peter Karl, Soyer, H. Peter, Khosrotehrani, Kiarash, Nguyen, Quan and Stark, Mitchell S. (2026). Precision diagnostics for early melanoma detection using spatial biology and AI guided image analysis. AACR Annual Meeting, San Diego, CA United States, 17-22 April 2026. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.AM2026-4021 |
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2026 Journal Article Second primary invasive cutaneous melanomas in Queensland over 4 decadesYoulden, Danny R., Atkinson, Victoria, Pinkham, Mark B., Barbour, Andrew, Xu, Wen, Khosrotehrani, Kiarash, Eastgate, Melissa, Lyle, Megan, Green, Solange, Nath, Artika, Negrello, Theresa, Cossio, Danica and Smithers, B. Mark (2026). Second primary invasive cutaneous melanomas in Queensland over 4 decades. Journal of Investigative Dermatology. doi: 10.1016/j.jid.2026.01.026 |