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2025

Journal Article

Immune checkpoint inhibitors in field cancerization and keratinocyte cancer prevention

Cox, Charlotte, Brown, Susan, Walpole, Euan, Roy, Edwige, Dousset, Lea, Ladwa, Rahul and Khosrotehrani, Kiarash (2025). Immune checkpoint inhibitors in field cancerization and keratinocyte cancer prevention. JAMA Dermatology, 161 (4), 383-390. doi: 10.1001/jamadermatol.2024.5750

Immune checkpoint inhibitors in field cancerization and keratinocyte cancer prevention

2024

Journal Article

Automated scoring of tumour infiltrating lymphocytes informs risk of death from thin melanoma: a nested case-case study

Tan, Samuel X., Aung, Thazin N., Claeson, Magdalena, Acs, Balazs, Zhou, Chenhao, Brown, Susan, Lambie, Duncan, Baade, Peter D., Pandeya, Nirmala, Soyer, H. Peter, Smithers, B. Mark, Whiteman, David C., Rimm, David L. and Khosrotehrani, Kiarash (2024). Automated scoring of tumour infiltrating lymphocytes informs risk of death from thin melanoma: a nested case-case study. Journal of the American Academy of Dermatology, 90 (1), 179-182. doi: 10.1016/j.jaad.2023.09.026

Automated scoring of tumour infiltrating lymphocytes informs risk of death from thin melanoma: a nested case-case study

2023

Journal Article

Development of physiologically relevant skin organoids from human induced pluripotent stem cells

Shafiee, Abbas, Sun, Jane, Ahmed, Imaan A., Phua, Felicia, Rossi, Gustavo R., Lin, Cheng‐Yu, Souza‐Fonseca‐Guimaraes, Fernando, Wolvetang, Ernst J., Brown, Jason and Khosrotehrani, Kiarash (2023). Development of physiologically relevant skin organoids from human induced pluripotent stem cells. Small, 20 (16) e2304879, 1-14. doi: 10.1002/smll.202304879

Development of physiologically relevant skin organoids from human induced pluripotent stem cells

2023

Journal Article

Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy

Wong, Ho Yi, Lee, Ruby C., Chong, Sharene, Kapadia, Stuti, Freeman, Michael, Murigneux, Valentine, Brown, Susan, Soyer, H. Peter, Roy, Edwige and Khosrotehrani, Kiarash (2023). Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy. Science Advances, 9 (19) eadf2384, 1-13. doi: 10.1126/sciadv.adf2384

Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy

2021

Journal Article

Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitors

Zhao, Jilai, Patel, Jatin, Kaur, Simranpreet, Sim, Seen-Ling, Wong, Ho Yi, Styke, Cassandra, Hogan, Isabella, Kahler, Sam, Hamilton, Hamish, Wadlow, Racheal, Dight, James, Hashemi, Ghazaleh, Sormani, Laura, Roy, Edwige, Yoder, Mervin C., Francois, Mathias and Khosrotehrani, Kiarash (2021). Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitors. Nature Communications, 12 (1) 2564, 1-17. doi: 10.1038/s41467-021-22717-9

Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitors

2020

Journal Article

Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors

Roy, Edwige, Wong, Ho Yi, Villani, Rehan, Rouille, Thomas, Salik, Basit, Sim, Seen Ling, Murigneux, Valentine, Stark, Mitchell S., Fink, J. Lynn, Soyer, H. Peter, Walker, Graeme, Lyons, J. Guy, Saunders, Nicholas and Khosrotehrani, Kiarash (2020). Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors. Cell Reports, 31 (9) 107702, 107702. doi: 10.1016/j.celrep.2020.107702

Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors

2019

Journal Article

Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells

Lukowski, Samuel W., Patel, Jatin, Andersen, Stacey B., Sim, Seen-Ling, Wong, Ho Yi, Tay, Joshua, Winkler, Ingrid, Powell, Joseph E. and Khosrotehrani, Kiarash (2019). Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells. Cell Reports, 27 (9), 2748-2758. doi: 10.1016/j.celrep.2019.04.102

Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells

2019

Journal Article

Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis

Donovan, Prudence, Patel, Jatin, Dight, James, Wong, Ho Yi, Sim, Seen-Ling, Murigneux, Valentine, Francois, Mathias and Khosrotehrani, Kiarash (2019). Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis. Nature Communications, 10 (1) 18, 18. doi: 10.1038/s41467-018-07961-w

Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis

2016

Journal Article

Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling

Roy, Edwige, Neufeld, Zoltan, Cerone, Luca, Wong, Ho Yi, Hodgson, Samantha, Livet, Jean and Khosrotehrani, Kiarash (2016). Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling. EMBO Journal, 35 (24), 2658-2670. doi: 10.15252/embj.201693806

Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling

2011

Journal Article

Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease

Peyrin-Biroulet, Laurent, Khosrotehrani, Kiarash, Carrat, Fabrice, Bouvier, Anne-Marie, Chevaux, Jean-Baptiste, Simon, Tabassome, Carbonnel, Frank, Colombel, Jean-Frederic, Dupas, Jean-Louis, Godeberge, Philippe, Hugot, Jean-Pierre, Lemann, Marc, Nahon, Stephane, Sabate, Jean-Marc, Tucat, Gilbert, Beaugerie, Laurent and For the Cesame Study Group (2011). Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease. Gastroenterology, 141 (5), 1621-1628.e5. doi: 10.1053/j.gastro.2011.06.050

Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease

2007

Journal Article

Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cells

Huu, Sau Nguyen, Oster, Michele, Uzan, Serge, Chareyre, Fabrice, Aractingi, Selim and Khosrotehrani, Kiarash (2007). Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cells. Proceedings of the National Academy of Sciences of the United States of America, 104 (6), 1871-1876. doi: 10.1073/pnas.0606490104

Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cells

2004

Journal Article

Transfer of fetal cells with multilineage potential to maternal tissue

Khosrotehrani, Kiarash, Johnson, Kirby L., Cha, Dong Hyun, Salomon, Robert N. and Bianchi, Diana W. (2004). Transfer of fetal cells with multilineage potential to maternal tissue. Jama: Journal of The American Medical Association, 292 (1), 75-80. doi: 10.1001/jama.292.1.75

Transfer of fetal cells with multilineage potential to maternal tissue

2026

Journal Article

The genomic and spatial transcriptomic landscape of seborrheic keratoses

Oey, Harald M., Kao, Yung-Ching, Lee, Katie J., Zhou, Chenhao, Brysland, Simone A., Jagirdar, Kasturee, Sunnefeldt, Erik, Hammerlindl, Sabrina, Tom, Lisa N., Tan, Jean-Marie, Lambie, Duncan, Sturm, Richard A., Schaider, Helmut, Dicker, Tony, Khosrotehrani, Kiarash, Soyer, H. Peter and Stark, Mitchell S. (2026). The genomic and spatial transcriptomic landscape of seborrheic keratoses. Journal of Investigative Dermatology. doi: 10.1016/j.jid.2026.03.048

The genomic and spatial transcriptomic landscape of seborrheic keratoses

2026

Journal Article

The burning question: Does exposure to low dose and low irradiance ultraviolet radiation lead to cutaneous <scp>DNA</scp> damage in people with skin types I– <scp>III</scp> ?

O'Hara, Montana, Hartel, Gunter, Byrne, Scott, Hacker, Elke, Hang, Xiaozhun, Ilinsky, Olga V., Ross, Tanya, Stewart, Linda, Hayward, Nicholas, Khosrotehrani, Kiarash, Sinclair, Craig, Whiteman, David C. and Neale, Rachel E. (2026). The burning question: Does exposure to low dose and low irradiance ultraviolet radiation lead to cutaneous DNA damage in people with skin types I– III ?. Photochemistry and Photobiology php.70120. doi: 10.1111/php.70120

The burning question: Does exposure to low dose and low irradiance ultraviolet radiation lead to cutaneous <scp>DNA</scp> damage in people with skin types I– <scp>III</scp> ?

2026

Journal Article

Skin cancer mortality in Australian and New Zealand kidney transplant recipients: A population-based cohort study using linked health data, 1990-2019

Forcey, Dana S, Rosales, Brenda Maria, Wyld, Melanie L, De La Mata, Nicole, Khosrotehrani, Kiarash and Webster, Angela C (2026). Skin cancer mortality in Australian and New Zealand kidney transplant recipients: A population-based cohort study using linked health data, 1990-2019. British Journal of Dermatology ljag232. doi: 10.1093/bjd/ljag232

Skin cancer mortality in Australian and New Zealand kidney transplant recipients: A population-based cohort study using linked health data, 1990-2019

2026

Journal Article

Rapid-access oncodermatology reduces systemic corticosteroid use and supports continuation of anticancer therapy after treatment-related cutaneous toxicity

Liu, Yuyang, Tan, Samuel X., Muller, Nicholas M., Shen, Xiaohua, Lee, Celine, Lau, Yit Nah, Atkinson, Victoria, Ladwa, Rahul, Karlsen, Emma-Anne and Khosrotehrani, Kiarash (2026). Rapid-access oncodermatology reduces systemic corticosteroid use and supports continuation of anticancer therapy after treatment-related cutaneous toxicity. JAAD International, 27, 70-72. doi: 10.1016/j.jdin.2026.04.020

Rapid-access oncodermatology reduces systemic corticosteroid use and supports continuation of anticancer therapy after treatment-related cutaneous toxicity

2026

Conference Publication

Review of HS genetics and whole exome sequencing of Australia's first Hidradenitis Suppurativa cohort

Maas, Ellie, Kahler, Sam, Snehlata, Kumari, Khosrotehrani, Kiarash, McMeniman, Erin and McInerney-Leo, Aideen (2026). Review of HS genetics and whole exome sequencing of Australia's first Hidradenitis Suppurativa cohort. Australasian College of Dermatologists, 58th Annual Scientific Meeting, Melbourne, VIC, Australia, 16-18 May 2026. Richmond, VIC, Australia: John Wiley & Sons. doi: 10.1111/ajd.70104

Review of HS genetics and whole exome sequencing of Australia's first Hidradenitis Suppurativa cohort

2026

Conference Publication

Why are thick melanomas lethal? Immune exclusion underpins recurrence in stage II melanoma

Tan, Samuel, Muller, Nicholas, Kao, Yung-Ching, Xiong, Zherui, Zhou, Chenhao, Gavanescu, Danielle, Roy, Edwige, Whiteman, David, Lambie, Duncan, Soyer, H. Peter, Stark, Mitchell, Nguyen, Quan and Khosrotehrani, Kiarash (2026). Why are thick melanomas lethal? Immune exclusion underpins recurrence in stage II melanoma. Australasian College of Dermatologists, 58th Annual Scientific Meeting, Melbourne, VIC, Australia, 16–18 May 2026. Richmond, VIC, Australia: John Wiley & Sons. doi: 10.1111/ajd.70101

Why are thick melanomas lethal? Immune exclusion underpins recurrence in stage II melanoma

2026

Conference Publication

Functional microbiome differences underlie wound healing outcomes

Matheus, Gabriela Gonzalez, Lim, Kai, Sivakumaran, Yogeesan, Khosrotehrani, Kiarash and Timothy, Wells (2026). Functional microbiome differences underlie wound healing outcomes. Australasian College of Dermatologists, 58th Annual Scientific Meeting 2026, Melbourne, VIC, Australia, 16 - 18 May 2026. Richmond, VIC, Australia: John Wiley & Sons.

Functional microbiome differences underlie wound healing outcomes

2026

Journal Article

A prebiotic and panthenol-containing repair balm improves tolerability of topical 5-fluorouracil field therapy for actinic keratoses: a randomised controlled trial

Tseng, Anne, Yu, Regina, Brown, Susan, Muller, Nicholas, Tan, Samuel X., Roy, Edwige, Nguyen, Suzanne, Kerob, Delphine and Khosrotehrani, Kiarash (2026). A prebiotic and panthenol-containing repair balm improves tolerability of topical 5-fluorouracil field therapy for actinic keratoses: a randomised controlled trial. Dermatology and Therapy, 16 (6), 3065-3078. doi: 10.1007/s13555-026-01775-1

A prebiotic and panthenol-containing repair balm improves tolerability of topical 5-fluorouracil field therapy for actinic keratoses: a randomised controlled trial