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2025

Journal Article

Immune checkpoint inhibitors in field cancerization and keratinocyte cancer prevention

Cox, Charlotte, Brown, Susan, Walpole, Euan, Roy, Edwige, Dousset, Lea, Ladwa, Rahul and Khosrotehrani, Kiarash (2025). Immune checkpoint inhibitors in field cancerization and keratinocyte cancer prevention. JAMA Dermatology, 161 (4), 383-390. doi: 10.1001/jamadermatol.2024.5750

Immune checkpoint inhibitors in field cancerization and keratinocyte cancer prevention

2024

Journal Article

Automated scoring of tumour infiltrating lymphocytes informs risk of death from thin melanoma: a nested case-case study

Tan, Samuel X., Aung, Thazin N., Claeson, Magdalena, Acs, Balazs, Zhou, Chenhao, Brown, Susan, Lambie, Duncan, Baade, Peter D., Pandeya, Nirmala, Soyer, H. Peter, Smithers, B. Mark, Whiteman, David C., Rimm, David L. and Khosrotehrani, Kiarash (2024). Automated scoring of tumour infiltrating lymphocytes informs risk of death from thin melanoma: a nested case-case study. Journal of the American Academy of Dermatology, 90 (1), 179-182. doi: 10.1016/j.jaad.2023.09.026

Automated scoring of tumour infiltrating lymphocytes informs risk of death from thin melanoma: a nested case-case study

2023

Journal Article

Development of physiologically relevant skin organoids from human induced pluripotent stem cells

Shafiee, Abbas, Sun, Jane, Ahmed, Imaan A., Phua, Felicia, Rossi, Gustavo R., Lin, Cheng‐Yu, Souza‐Fonseca‐Guimaraes, Fernando, Wolvetang, Ernst J., Brown, Jason and Khosrotehrani, Kiarash (2023). Development of physiologically relevant skin organoids from human induced pluripotent stem cells. Small, 20 (16) e2304879, 1-14. doi: 10.1002/smll.202304879

Development of physiologically relevant skin organoids from human induced pluripotent stem cells

2023

Journal Article

Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy

Wong, Ho Yi, Lee, Ruby C., Chong, Sharene, Kapadia, Stuti, Freeman, Michael, Murigneux, Valentine, Brown, Susan, Soyer, H. Peter, Roy, Edwige and Khosrotehrani, Kiarash (2023). Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy. Science Advances, 9 (19) eadf2384, 1-13. doi: 10.1126/sciadv.adf2384

Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy

2021

Journal Article

Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitors

Zhao, Jilai, Patel, Jatin, Kaur, Simranpreet, Sim, Seen-Ling, Wong, Ho Yi, Styke, Cassandra, Hogan, Isabella, Kahler, Sam, Hamilton, Hamish, Wadlow, Racheal, Dight, James, Hashemi, Ghazaleh, Sormani, Laura, Roy, Edwige, Yoder, Mervin C., Francois, Mathias and Khosrotehrani, Kiarash (2021). Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitors. Nature Communications, 12 (1) 2564, 1-17. doi: 10.1038/s41467-021-22717-9

Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitors

2020

Journal Article

Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors

Roy, Edwige, Wong, Ho Yi, Villani, Rehan, Rouille, Thomas, Salik, Basit, Sim, Seen Ling, Murigneux, Valentine, Stark, Mitchell S., Fink, J. Lynn, Soyer, H. Peter, Walker, Graeme, Lyons, J. Guy, Saunders, Nicholas and Khosrotehrani, Kiarash (2020). Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors. Cell Reports, 31 (9) 107702, 107702. doi: 10.1016/j.celrep.2020.107702

Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors

2019

Journal Article

Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells

Lukowski, Samuel W., Patel, Jatin, Andersen, Stacey B., Sim, Seen-Ling, Wong, Ho Yi, Tay, Joshua, Winkler, Ingrid, Powell, Joseph E. and Khosrotehrani, Kiarash (2019). Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells. Cell Reports, 27 (9), 2748-2758. doi: 10.1016/j.celrep.2019.04.102

Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells

2019

Journal Article

Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis

Donovan, Prudence, Patel, Jatin, Dight, James, Wong, Ho Yi, Sim, Seen-Ling, Murigneux, Valentine, Francois, Mathias and Khosrotehrani, Kiarash (2019). Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis. Nature Communications, 10 (1) 18, 18. doi: 10.1038/s41467-018-07961-w

Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis

2016

Journal Article

Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling

Roy, Edwige, Neufeld, Zoltan, Cerone, Luca, Wong, Ho Yi, Hodgson, Samantha, Livet, Jean and Khosrotehrani, Kiarash (2016). Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling. EMBO Journal, 35 (24), 2658-2670. doi: 10.15252/embj.201693806

Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling

2011

Journal Article

Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease

Peyrin-Biroulet, Laurent, Khosrotehrani, Kiarash, Carrat, Fabrice, Bouvier, Anne-Marie, Chevaux, Jean-Baptiste, Simon, Tabassome, Carbonnel, Frank, Colombel, Jean-Frederic, Dupas, Jean-Louis, Godeberge, Philippe, Hugot, Jean-Pierre, Lemann, Marc, Nahon, Stephane, Sabate, Jean-Marc, Tucat, Gilbert, Beaugerie, Laurent and For the Cesame Study Group (2011). Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease. Gastroenterology, 141 (5), 1621-1628.e5. doi: 10.1053/j.gastro.2011.06.050

Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease

2007

Journal Article

Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cells

Huu, Sau Nguyen, Oster, Michele, Uzan, Serge, Chareyre, Fabrice, Aractingi, Selim and Khosrotehrani, Kiarash (2007). Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cells. Proceedings of the National Academy of Sciences of the United States of America, 104 (6), 1871-1876. doi: 10.1073/pnas.0606490104

Maternal neoangiogenesis during pregnancy partly derives from fetal endothelial progenitor cells

2004

Journal Article

Transfer of fetal cells with multilineage potential to maternal tissue

Khosrotehrani, Kiarash, Johnson, Kirby L., Cha, Dong Hyun, Salomon, Robert N. and Bianchi, Diana W. (2004). Transfer of fetal cells with multilineage potential to maternal tissue. Jama: Journal of The American Medical Association, 292 (1), 75-80. doi: 10.1001/jama.292.1.75

Transfer of fetal cells with multilineage potential to maternal tissue

2025

Journal Article

Coordinated development of immune cell populations in vascularized skin organoids from human induced pluripotent stem cells

Mostina, Mitchell, Sun, Jane, Sim, Seen Ling, Ahmed, Imaan A., Souza-Fonesca-Guimaraes, Fernando, Wolvetang, Ernst J., Brown, Jason, Kumari, Snehlata, Khosrotehrani, Kiarash and Shafiee, Abbas (2025). Coordinated development of immune cell populations in vascularized skin organoids from human induced pluripotent stem cells. Advanced Healthcare Materials e02108. doi: 10.1002/adhm.202502108

Coordinated development of immune cell populations in vascularized skin organoids from human induced pluripotent stem cells

2025

Journal Article

Criteria for Commencing and Continuing Subsidised Janus Kinase Inhibitor Therapy in Australian Alopecia Areata Patients—Results From an Australian Expert Consensus Exercise

Thomas, Meryl, Hankins, Madeline, Darchini‐Maragheh, Emadodin, Bokhari, Laita, Eisman, Samantha, Yip, Leona, York, Katherine, Li, Jane, Sharma, Pooja, Triwongwaranat, Daranporn, Chitreddy, Vijaya, Ghiya, Ragini, Kushnir‐Grinbaum, Daniella, Frewen, John, Yong, Shin Shen, Rathnayake, Deepani, Cranwell, William, Wall, Dmitri, Varathan, Vanathy, Khosrotehrani, Kiarash, Orchard, David, Moussa, Anthony, Paranjape, Meghana and Sinclair, Rodney (2025). Criteria for Commencing and Continuing Subsidised Janus Kinase Inhibitor Therapy in Australian Alopecia Areata Patients—Results From an Australian Expert Consensus Exercise. Australasian Journal of Dermatology ajd.14556. doi: 10.1111/ajd.14556

Criteria for Commencing and Continuing Subsidised Janus Kinase Inhibitor Therapy in Australian Alopecia Areata Patients—Results From an Australian Expert Consensus Exercise

2025

Conference Publication

Topical sirolimus prevents cutaneous squamous cell carcinomas by disrupting the balance between differentiation and proliferation

Dousset, L., Zhou, C., Kao, Y., Tan, S., Muller, N., Sormani, L., Cox, C., Soyer, H.P., Stark, M.S., Wong, H., Roy, E. and Khosrotehrani, K. (2025). Topical sirolimus prevents cutaneous squamous cell carcinomas by disrupting the balance between differentiation and proliferation. Society for Investigative Dermatology (SID) 2025 Meeting, San Diego, CA United States, 7-10 May 2025. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2025.06.777

Topical sirolimus prevents cutaneous squamous cell carcinomas by disrupting the balance between differentiation and proliferation

2025

Conference Publication

Spatial transcriptomics reveals molecular determinants of mortality in thin melanoma

Zhou, C., Tan, S.X., Kao, Y., Claeson, M., Brown, S., Lambie, D., Whiteman, D.C., Pandeya, N., Olsen, C.M., Barbour, A., MacGregor, S., Soyer, H.P., Stark, M.S., Hayward, N., Smithers, B.M., Nguyen, Q. and Khosrotehrani, K. (2025). Spatial transcriptomics reveals molecular determinants of mortality in thin melanoma. Society for Investigative Dermatology (SID) 2025 Meeting, San Diego, CA United States, 7-10 May 2025. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2025.06.109

Spatial transcriptomics reveals molecular determinants of mortality in thin melanoma

2025

Conference Publication

Epithelial-mesenchymal transition and immune exclusion underpin the natural history of primary cutaneous melanoma

Tan, S.X., Muller, N., Zhou, C., Vipulaguna, N., Kao, Y., Whiteman, D.C., Soyer, H.P., Stark, M.S., Nguyen, Q. and Khosrotehrani, K. (2025). Epithelial-mesenchymal transition and immune exclusion underpin the natural history of primary cutaneous melanoma. Society for Investigative Dermatology (SID) 2025 Meeting, San Diego, CA United States, 7-10 May 2025. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2025.06.953

Epithelial-mesenchymal transition and immune exclusion underpin the natural history of primary cutaneous melanoma

2025

Journal Article

Sociodemographic disparities in melanoma stage at diagnosis: the role of socioeconomic status and residential location

Gavanescu, Danielle, Dobson, Annette, Sharma, Hansa, Tan, Samuel X., Muller, Nicholas M., Hughes, Maria Celia B., Malt, Maryrose K., Smithers, B. Mark, Khosrotehrani, Kiarash and von Schuckmann, Lena A. (2025). Sociodemographic disparities in melanoma stage at diagnosis: the role of socioeconomic status and residential location. Cancer Epidemiology, Biomarkers and Prevention, OF1-OF5. doi: 10.1158/1055-9965.epi-25-0372

Sociodemographic disparities in melanoma stage at diagnosis: the role of socioeconomic status and residential location

2025

Journal Article

Bigger might actually be better: A prospective investigation into the association between body mass index, tumour stage, and recurrence in patients with high-risk primary melanoma

Sharma, Hansa, Hughes, Maria Celia B., Gavanescu, Danielle, Malt, Maryrose, Smithers, B Mark, Khosrotehrani, Kiarash and von Schuckmann, Lena (2025). Bigger might actually be better: A prospective investigation into the association between body mass index, tumour stage, and recurrence in patients with high-risk primary melanoma. Journal of the American Academy of Dermatology. doi: 10.1016/j.jaad.2025.07.043

Bigger might actually be better: A prospective investigation into the association between body mass index, tumour stage, and recurrence in patients with high-risk primary melanoma

2025

Journal Article

The Involvement of IL-34 in Inflammatory and Malignant Skin Diseases

Dang, Thi Viet Trinh, Mehdi, Ahmed M., Kumari, Snehlata, Khosrotehrani, Kiarash, Frazer, Ian H., Hume, David A. and Chandra, Janin (2025). The Involvement of IL-34 in Inflammatory and Malignant Skin Diseases. Journal of Investigative Dermatology, 1-13. doi: 10.1016/j.jid.2025.05.003

The Involvement of IL-34 in Inflammatory and Malignant Skin Diseases