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2021

Journal Article

Microfluidic assembly of pomegranate-like hierarchical microspheres for efflux regulation in oral drug delivery

Raza, Aun, Alavi, Seyed Ebrahim, Sime, Fekade Bruck, Han, Felicity Y., Roberts, Jason A., Popat, Amirali, Falconer, James R. and Kumeria, Tushar (2021). Microfluidic assembly of pomegranate-like hierarchical microspheres for efflux regulation in oral drug delivery. Acta Biomaterialia, 126, 277-290. doi: 10.1016/j.actbio.2021.03.042

Microfluidic assembly of pomegranate-like hierarchical microspheres for efflux regulation in oral drug delivery

2021

Journal Article

Sustained release ketamine-loaded porous silicon-PLGA microparticles prepared by an optimized supercritical CO2 process

Xu, Weizhi, Zhao, Zonglan, Falconer, James, Whittaker, Andrew K., Popat, Amirali, Smith, Maree T., Kumeria, Tushar and Han, Felicity Y. (2021). Sustained release ketamine-loaded porous silicon-PLGA microparticles prepared by an optimized supercritical CO2 process. Drug Delivery and Translational Research, 12 (3), 676-694. doi: 10.1007/s13346-021-00991-w

Sustained release ketamine-loaded porous silicon-PLGA microparticles prepared by an optimized supercritical CO2 process

2021

Journal Article

Frontiers in the treatment of glioblastoma: past, present and emerging

Janjua, Taskeen Iqbal, Rewatkar, Prarthana, Ahmed-Cox, Aria, Saeed, Iqira, Mansfeld, Friederike M., Kulshreshtha, Ritu, Kumeria, Tushar, Ziegler, David S., Kavallaris, Maria, Mazzieri, Roberta and Popat, Amirali (2021). Frontiers in the treatment of glioblastoma: past, present and emerging. Advanced Drug Delivery Reviews, 171, 108-138. doi: 10.1016/j.addr.2021.01.012

Frontiers in the treatment of glioblastoma: past, present and emerging

2021

Journal Article

PLGA encapsulated γ-cyclodextrin-meropenem inclusion complex formulation for oral delivery

Raza, Aun, Miles, Jared A., Bruck Sime, Fekade, Ross, Benjamin P., Roberts, Jason A., Popat, Amirali, Kumeria, Tushar and Falconer, James R. (2021). PLGA encapsulated γ-cyclodextrin-meropenem inclusion complex formulation for oral delivery. International Journal of Pharmaceutics, 597 120280, 120280. doi: 10.1016/j.ijpharm.2021.120280

PLGA encapsulated γ-cyclodextrin-meropenem inclusion complex formulation for oral delivery

2021

Journal Article

Supercritical carbon dioxide assisted complexation of benznidazole: γ-cyclodextrin for improved dissolution

Ndayishimiye, John, Popat, Amirali, Kumeria, Tushar, Blaskovich, Mark A.T. and Falconer, James Robert (2021). Supercritical carbon dioxide assisted complexation of benznidazole: γ-cyclodextrin for improved dissolution. International Journal of Pharmaceutics, 596 120240, 120240. doi: 10.1016/j.ijpharm.2021.120240

Supercritical carbon dioxide assisted complexation of benznidazole: γ-cyclodextrin for improved dissolution

2021

Journal Article

Protein nanoparticles for enhanced oral delivery of coenzyme-Q10: in vitro and in silico studies

Banun, Vanessa Jane, Rewatkar, Prarthana, Chaudhary, Zanib, Qu, Zhi, Janjua, Taskeen, Patil, Anuja, Wu, Yuao, Ta, Hang T., Bansal, Nidhi, Miles, Jared A., Ross, Benjamin P., Kumeria, Tushar and Popat, Amirali (2021). Protein nanoparticles for enhanced oral delivery of coenzyme-Q10: in vitro and in silico studies. ACS Biomaterials Science and Engineering, 9 (6) acsbiomaterials.0c01354, 2846-2856. doi: 10.1021/acsbiomaterials.0c01354

Protein nanoparticles for enhanced oral delivery of coenzyme-Q10: in vitro and in silico studies

2021

Journal Article

Emerging nanomedicines for the treatment of atopic dermatitis

Parekh, Khushali, Mehta, Tejal A., Dhas, Namdev, Kumar, Pavan and Popat, Amirali (2021). Emerging nanomedicines for the treatment of atopic dermatitis. AAPS PharmSciTech, 22 (2) 55, 55. doi: 10.1208/s12249-021-01920-3

Emerging nanomedicines for the treatment of atopic dermatitis

2021

Journal Article

Liquid CO2 formulated mesoporous silica nanoparticles for pH-responsive oral delivery of meropenem

Raza, Aun, Sime, Fekade Bruck, Cabot, Peter J., Roberts, Jason A., Falconer, James R., Kumeria, Tushar and Popat, Amirali (2021). Liquid CO2 formulated mesoporous silica nanoparticles for pH-responsive oral delivery of meropenem. ACS Biomaterials Science and Engineering, 7 (5) acsbiomaterials.0c01284, 1836-1853. doi: 10.1021/acsbiomaterials.0c01284

Liquid CO2 formulated mesoporous silica nanoparticles for pH-responsive oral delivery of meropenem

2021

Journal Article

Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma

Janjua, Taskeen Iqbal, Ahmed-Cox, Aria, Meka, Anand Kumar, Mansfeld, Friederike M., Forgham, Helen, Ignacio, Rosa Mistica C., Cao, Yuxue, McCarroll, Joshua A., Mazzieri, Roberta, Kavallaris, Maria and Popat, Amirali (2021). Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma. Nanoscale, 13 (40), 16909-16922. doi: 10.1039/d1nr03553c

Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma

2021

Journal Article

Engineering mesoporous silica nanoparticles towards oral delivery of vancomycin

Ndayishimiye, John, Cao, Yuxue, Kumeria, Tushar, Blaskovich, Mark A. T., Falconer, James Robert and Popat, Amirali (2021). Engineering mesoporous silica nanoparticles towards oral delivery of vancomycin. Journal of Materials Chemistry B, 9 (35), 7145-7166. doi: 10.1039/d1tb01430g

Engineering mesoporous silica nanoparticles towards oral delivery of vancomycin

2021

Journal Article

Rapid fabrication of homogeneously distributed hyper-branched gold nanostructured electrode based electrochemical immunosensor for detection of protein biomarkers

Bakshi, Shrishty, Mehta, Samriddhi, Kumeria, Tushar, Shiddiky, Muhammad J.A., Popat, Amirali, Choudhury, Sangeeta, Bose, Sudeep and Nayak, Ranu (2021). Rapid fabrication of homogeneously distributed hyper-branched gold nanostructured electrode based electrochemical immunosensor for detection of protein biomarkers. Sensors and Actuators, B: Chemical, 326 128803, 128803. doi: 10.1016/j.snb.2020.128803

Rapid fabrication of homogeneously distributed hyper-branched gold nanostructured electrode based electrochemical immunosensor for detection of protein biomarkers

2020

Journal Article

Oral meropenem for superbugs: challenges and opportunities

Raza, Aun, Ngieng, Shih Chen, Sime, Fekade Bruck, Cabot, Peter J., Roberts, Jason A., Popat, Amirali, Kumeria, Tushar and Falconer, James R. (2020). Oral meropenem for superbugs: challenges and opportunities. Drug Discovery Today, 26 (2), 551-560. doi: 10.1016/j.drudis.2020.11.004

Oral meropenem for superbugs: challenges and opportunities

2020

Journal Article

One‐pot synthesis of pH‐responsive eudragit‐mesoporous silica nanocomposites enable colonic delivery of glucocorticoids for the treatment of inflammatory bowel disease

Qu, Zhi, Wong, Kuan Yau, Moniruzzaman, Md., Begun, Jakob, Santos, Hélder A, Hasnain, Sumaira Z., Kumeria, Tushar, McGuckin, Michael A. and Popat, Amirali (2020). One‐pot synthesis of pH‐responsive eudragit‐mesoporous silica nanocomposites enable colonic delivery of glucocorticoids for the treatment of inflammatory bowel disease. Advanced Therapeutics, 4 (2) 2000165, 2000165. doi: 10.1002/adtp.202000165

One‐pot synthesis of pH‐responsive eudragit‐mesoporous silica nanocomposites enable colonic delivery of glucocorticoids for the treatment of inflammatory bowel disease

2020

Journal Article

Silica nanoparticles: a promising platform for enhanced oral delivery of macromolecules

Abeer, Muhammad Mustafa, Rewatkar, Prarthana, Qu, Zhi, Talekar, Meghna, Kleitz, Freddy, Schmid, Roman, Lindén, Mika, Kumeria, Tushar and Popat, Amirali (2020). Silica nanoparticles: a promising platform for enhanced oral delivery of macromolecules. Journal of Controlled Release, 326, 544-555. doi: 10.1016/j.jconrel.2020.07.021

Silica nanoparticles: a promising platform for enhanced oral delivery of macromolecules

2020

Journal Article

Formulation technologies and advances for oral delivery of novel nitroimidazoles and antimicrobial peptides

Ndayishimiye, John, Popat, Amirali, Blaskovich, Mark and Falconer, James Robert (2020). Formulation technologies and advances for oral delivery of novel nitroimidazoles and antimicrobial peptides. Journal of Controlled Release, 324, 728-749. doi: 10.1016/j.jconrel.2020.05.002

Formulation technologies and advances for oral delivery of novel nitroimidazoles and antimicrobial peptides

2020

Journal Article

Gastro-protective protein-silica nanoparticles formulation for oral drug delivery: In vitro release, cytotoxicity and mitochondrial activity

Juère, Estelle, Del Favero, Giorgia, Masse, Florence, Marko, Doris, Popat, Amirali, Florek, Justyna, Caillard, Romain and Kleitz, Freddy (2020). Gastro-protective protein-silica nanoparticles formulation for oral drug delivery: In vitro release, cytotoxicity and mitochondrial activity. European Journal of Pharmaceutics and Biopharmaceutics, 151, 171-180. doi: 10.1016/j.ejpb.2020.03.015

Gastro-protective protein-silica nanoparticles formulation for oral drug delivery: In vitro release, cytotoxicity and mitochondrial activity

2020

Journal Article

Oral delivery of β-lactoglobulin nanospheres encapsulated resveratrol alleviates inflammation in Winnie mice with spontaneous ulcerative colitis

Pujara, Naisarg, Wong, Kuan Yau, Qu, Zhi, Wang, Ran, Moniruzzaman, Md., Rewatkar, Prarthana, Kumeria, Tushar, Ross, Benjamin P., McGuckin, Michael and Popat, Amirali (2020). Oral delivery of β-lactoglobulin nanospheres encapsulated resveratrol alleviates inflammation in Winnie mice with spontaneous ulcerative colitis. Molecular Pharmaceutics, 18 (2) acs.molpharmaceut.0c00048, 627-640. doi: 10.1021/acs.molpharmaceut.0c00048

Oral delivery of β-lactoglobulin nanospheres encapsulated resveratrol alleviates inflammation in Winnie mice with spontaneous ulcerative colitis

2020

Journal Article

The solid progress of nanomedicine

Martins, João Pedro, das Neves, José, de la Fuente, María, Celia, Christian, Florindo, Helena, Günday-Türeli, Nazende, Popat, Amirali, Santos, José Luis, Sousa, Flávia, Schmid, Ruth, Wolfram, Joy, Sarmento, Bruno and Santos, Hélder A. (2020). The solid progress of nanomedicine. Drug Delivery and Translational Research, 10 (3), 726-729. doi: 10.1007/s13346-020-00743-2

The solid progress of nanomedicine

2020

Journal Article

Polymer-mesoporous silica nanoparticle core-shell nanofibers as a dual-drug-delivery system for guided tissue regeneration

Xu, Chun, Cao, Yuxue, Lei, Chang, Li, Zhihao, Kumeria, Tushar, Meka, Anand Kumar, Xu, Jia, Liu, Jingyu, Yan, Cheng, Luo, Lihua, Khademhosseini, Ali, Popat, Amirali, He, Yan and Ye, Qingsong (2020). Polymer-mesoporous silica nanoparticle core-shell nanofibers as a dual-drug-delivery system for guided tissue regeneration. ACS Applied Nano Materials, 3 (2), 1457-1467. doi: 10.1021/acsanm.9b02298

Polymer-mesoporous silica nanoparticle core-shell nanofibers as a dual-drug-delivery system for guided tissue regeneration

2019

Journal Article

Efficient photoacoustic imaging using indocyanine green (ICG) loaded functionalized mesoporous silica nanoparticles

Chaudhary, Zanib, Khan, Gul Majid, Abeer, Muhammad Mustafa, Pujara, Naisarg, Wan-Chi Tse, Brian, McGuckin, Michael A., Popat, Amirali and Kumeria, Tushar (2019). Efficient photoacoustic imaging using indocyanine green (ICG) loaded functionalized mesoporous silica nanoparticles. Biomaterials Science, 7 (12), 5002-5015. doi: 10.1039/c9bm00822e

Efficient photoacoustic imaging using indocyanine green (ICG) loaded functionalized mesoporous silica nanoparticles