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2020 Journal Article Correction: The cysteine (Cys) residues Cys-6 and Cys-111 in mutant superoxide dismutase 1 (SOD1) A4V are required for induction of endoplasmic reticulum stress in amyotrophic lateral sclerosisPerri, Emma R., Parakh, Sonam, Vidal, Marta, Mehta, Prachi, Ma, Yi, Walker, Adam K. and Atkin, Julie D. (2020). Correction: The cysteine (Cys) residues Cys-6 and Cys-111 in mutant superoxide dismutase 1 (SOD1) A4V are required for induction of endoplasmic reticulum stress in amyotrophic lateral sclerosis. Journal of Molecular Neuroscience, 70 (9), 1369-1369. doi: 10.1007/s12031-020-01617-5 |
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2020 Journal Article The cysteine (Cys) residues Cys-6 and Cys-111 in mutant superoxide dismutase 1 (SOD1) A4V are required for induction of endoplasmic reticulum stress in amyotrophic lateral sclerosisPerri, Emma R., Parakh, Sonam, Vidal, Marta, Mehta, Prachi, Ma, Yi, Walker, Adam K. and Atkin, Julie D. (2020). The cysteine (Cys) residues Cys-6 and Cys-111 in mutant superoxide dismutase 1 (SOD1) A4V are required for induction of endoplasmic reticulum stress in amyotrophic lateral sclerosis. Journal of Molecular Neuroscience, 70 (9), 1357-1368. doi: 10.1007/s12031-020-01551-6 |
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2019 Journal Article Proteomics approaches for biomarker and drug target discovery in ALS and FTDHedl, Thomas J., San Gil, Rebecca, Cheng, Flora, Rayner, Stephanie L., Davidson, Jennilee M., De Luca, Alana, Villalva, Maria D., Ecroyd, Heath, Walker, Adam K. and Lee, Albert (2019). Proteomics approaches for biomarker and drug target discovery in ALS and FTD. Frontiers in Neuroscience, 13 (JUN) 548, 548. doi: 10.3389/fnins.2019.00548 |
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2019 Journal Article Label-free fluorescent poly(amidoamine) dendrimer for traceable and controlled drug deliveryWang, Guoying, Fu, Libing, Walker, Adam, Chen, Xianfeng, Lovejoy, David B., Hao, Mingcong, Lee, Albert, Chung, Roger, Rizos, Helen, Irvine, Mal, Zheng, Meng, Liu, Xiuhua, Lu, Yiqing and Shi, Bingyang (2019). Label-free fluorescent poly(amidoamine) dendrimer for traceable and controlled drug delivery. Biomacromolecules, 20 (5), 2148-2158. doi: 10.1021/acs.biomac.9b00494 |
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2019 Journal Article The Pathobiology of TDP-43 C-Terminal Fragments in ALS and FTLDBerning, Britt A. and Walker, Adam K. (2019). The Pathobiology of TDP-43 C-Terminal Fragments in ALS and FTLD. Frontiers in Neuroscience, 13 (APR) 335, 335. doi: 10.3389/fnins.2019.00335 |
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2019 Journal Article Genetic and immunopathological analysis of CHCHD10 in Australian amyotrophic lateral sclerosis and frontotemporal dementia and transgenic TDP-43 miceMcCann, Emily P., Fifita, Jennifer A., Grima, Natalie, Galper, Jasmin, Mehta, Prachi, Freckleton, Sarah E., Zhang, Katharine Y., Henden, Lyndal, Hogan, Alison L., Chan Moi Fat, Sandrine, Wu, Sharlynn S.L., Jagaraj, Cyril J., Berning, Britt A., Williams, Kelly Louise, Twine, Natalie A., Bauer, Denis, Piguet, Olivier, Hodges, John, Kwok, John B.J., Halliday, Glenda M., Kiernan, Matthew C., Atkin, Julie, Rowe, Dominic B., Nicholson, Garth A., Walker, Adam K., Blair, Ian P. and Yang, Shu (2019). Genetic and immunopathological analysis of CHCHD10 in Australian amyotrophic lateral sclerosis and frontotemporal dementia and transgenic TDP-43 mice. Journal of Neurology, Neurosurgery and Psychiatry, 91 (2), 162-2019. doi: 10.1136/jnnp-2019-321790 |
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2018 Journal Article Stilbenes from Veratrum maackii Regel protect against ethanol-induced DNA damage in mouse cerebellum and cerebral cortexWu, Yantong, Li, Shasha, Liu, Jinjin, Liu, Xiping, Ruan, Weimin, Lu, Jengwei, Liu, Yong, Lawson, Tom, Shimoni, Olga, Lovejoy, David B., Walker, Adam K., Cong, Yue and Shi, Bingyang (2018). Stilbenes from Veratrum maackii Regel protect against ethanol-induced DNA damage in mouse cerebellum and cerebral cortex. ACS Chemical Neuroscience, 9 (7), 1616-1624. doi: 10.1021/acschemneuro.8b00006 |
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2018 Journal Article ERp57 is protective against mutant SOD1-induced cellular pathology in amyotrophic lateral sclerosisParakh, Sonam, Jagaraj, Cyril J., Vidal, Marta, Ragagnin, Audrey M. G., Perri, Emma R., Konopka, Anna, Toth, Reka P., Galper, Jasmin, Blair, Ian P., Thomas, Colleen J., Walker, Adam K., Yang, Shu, Spencer, Damian M. and Atkin, Julie D. (2018). ERp57 is protective against mutant SOD1-induced cellular pathology in amyotrophic lateral sclerosis. Human Molecular Genetics, 27 (8), 1311-1331. doi: 10.1093/hmg/ddy041 |
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2017 Journal Article Casein kinase II phosphorylation of cyclin F at serine 621 regulates the Lys48-ubiquitylation E3 ligase activity of the SCF(cyclin F) complexLee, Albert, Rayner, Stephanie L., De Luca, Alana, Gwee, Serene S. L., Morsch, Marco, Sundaramoorthy, Vinod, Shahheydari, Hamideh, Ragagnin, Audrey, Shi, Bingyang, Yang, Shu, Williams, Kelly L., Don, Emily K., Walker, Adam K., Zhang, Katharine Y., Yerbury, Justin J., Cole, Nicholas J., Atkin, Julie D., Blair, Ian P., Molloy, Mark P. and Chung, Roger S. (2017). Casein kinase II phosphorylation of cyclin F at serine 621 regulates the Lys48-ubiquitylation E3 ligase activity of the SCF(cyclin F) complex. Open Biology, 7 (10) 170058, 170058. doi: 10.1098/rsob.170058 |
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2017 Journal Article Erratum: Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis (Human molecular genetics (2015) 24 13 (3830-3846))Sundaramoorthy, Vinod, Walker, Adam K., Tan, Vanessa, Fifita, Jennifer A., Mccann, Emily P., Williams, Kelly L., Blair, Ian P., Guillemin, Gilles J., Farg, Manal A. and Atkin, Julie D. (2017). Erratum: Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis (Human molecular genetics (2015) 24 13 (3830-3846)). Human Molecular Genetics, 26 (17), 3452-3452. doi: 10.1093/hmg/ddx268 |
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2017 Journal Article Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagyLee, Albert, Rayner, Stephanie L., Gwee, Serene S. L., De Luca, Alana, Shahheydari, Hamideh, Sundaramoorthy, Vinod, Ragagnin, Audrey, Morsch, Marco, Radford, Rowan, Galper, Jasmin, Freckleton, Sarah, Shi, Bingyang, Walker, Adam K., Don, Emily K., Cole, Nicholas J., Yang, Shu, Williams, Kelly L., Yerbury, Justin J., Blair, Ian P., Atkin, Julie D., Molloy, Mark P. and Chung, Roger S. (2017). Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy. Cellular and Molecular Life Sciences, 75 (2), 335-354. doi: 10.1007/s00018-017-2632-8 |
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2017 Journal Article Protein quality control and the amyotrophic lateral sclerosis/frontotemporal dementia continuumShahheydari, Hamideh, Ragagnin, Audrey, Walker, Adam K., Toth, Reka P., Vidal, Marta, Jagaraj, Cyril J., Perri, Emma R., Konopka, Anna, Sultana, Jessica M. and Atkin, Julie D. (2017). Protein quality control and the amyotrophic lateral sclerosis/frontotemporal dementia continuum. Frontiers in Molecular Neuroscience, 10 119, 1-25. doi: 10.3389/fnmol.2017.00119 |
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2015 Journal Article An insoluble frontotemporal lobar degeneration-associated TDP-43 C-terminal fragment causes neurodegeneration and hippocampus pathology in transgenic miceWalker, Adam K., Tripathy, Kalyan, Restrepo, Clark R., Ge, Guanghui, Xu, Yan, Kwong, Linda K., Trojanowski, John Q. and Lee, Virginia M. -Y. (2015). An insoluble frontotemporal lobar degeneration-associated TDP-43 C-terminal fragment causes neurodegeneration and hippocampus pathology in transgenic mice. Human Molecular Genetics, 24 (25), 7241-7254. doi: 10.1093/hmg/ddv424 |
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2015 Journal Article Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43Walker, Adam K., Spiller, Krista J., Ge, Guanghui, Zheng, Allen, Xu, Yan, Zhou, Melissa, Tripathy, Kalyan, Kwong, Linda K., Trojanowski, John Q. and Lee, Virginia M. -Y. (2015). Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43. Acta Neuropathologica, 130 (5), 643-660. doi: 10.1007/s00401-015-1460-x |
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2015 Journal Article Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosisSundaramoorthy, Vinod, Walker, Adam K., Tan, Vanessa, Fifita, Jennifer A., Mccann, Emily P., Williams, Kelly L., Blair, Ian P., Guillemin, Gilles J., Farg, Manal A. and Atkin, Julie D. (2015). Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis. Human Molecular Genetics, 24 (13), 3830-3846. doi: 10.1093/hmg/ddv126 |
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2014 Journal Article Astrocytic TDP-43 pathology in Alexander diseaseWalker, Adam K., Daniels, Christine M. LaPash, Goldman, James E., Trojanowski, John Q., Lee, Virginia M. -Y. and Messing, Albee (2014). Astrocytic TDP-43 pathology in Alexander disease. Journal of Neuroscience, 34 (19), 6448-6458. doi: 10.1523/JNEUROSCI.0248-14.2014 |
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2014 Journal Article Mutant SOD1 inhibits ER-Golgi transport in amyotrophic lateral sclerosisAtkin, Julie D., Farg, Manal A., Soo, Kai Ying, Walker, Adam K., Halloran, Mark, Turner, Bradley J., Nagley, Phillip and Horne, Malcolm K. (2014). Mutant SOD1 inhibits ER-Golgi transport in amyotrophic lateral sclerosis. Journal of Neurochemistry, 129 (1), 190-204. doi: 10.1111/jnc.12493 |
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2014 Journal Article Novel monoclonal antibodies to normal and pathologically altered human TDP-43 proteinsKwong, Linda K., Irwin, David J., Walker, Adam K., Xu, Yan, Riddle, Dawn M, Trojanowski, John Q. and Lee, Virginia M. Y. (2014). Novel monoclonal antibodies to normal and pathologically altered human TDP-43 proteins. Acta Neuropathologica Communications, 2 (1) 33. doi: 10.1186/2051-5960-2-33 |
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2013 Journal Article ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formationWalker, Adam K., Soo, Kai Y., Sundaramoorthy, Vinod, Parakh, Sonam, Ma, Yi, Farg, Manal A., Wallace, Robyn H., Crouch, Peter J., Turner, Bradley J., Horne, Malcolm K. and Atkin, Julie D. (2013). ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formation. PLoS One, 8 (11) e81170, e81170.1-e81170.12. doi: 10.1371/journal.pone.0081170 |
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2013 Journal Article Extracellular wildtype and mutant SOD1 induces ER-Golgi pathology characteristic of amyotrophic lateral sclerosis in neuronal cellsSundaramoorthy, Vinod, Walker, Adam K., Yerbury, Justin, Soo, Kai Ying, Farg, Manal A., Hoang, Vy, Zeineddine, Rafaa, Spencer, Damian and Atkin, Julie D. (2013). Extracellular wildtype and mutant SOD1 induces ER-Golgi pathology characteristic of amyotrophic lateral sclerosis in neuronal cells. Cellular and Molecular Life Sciences, 70 (21), 4181-4195. doi: 10.1007/s00018-013-1385-2 |
