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2024

Conference Publication

POS0303 CROSSING THE BARRIERS: DYSBIOSIS AND SUBCLINICAL UTERINE INFLAMMATION IN THE PATHOGENESIS OF AxSpA IN FEMALES. ANOTHER BREAK IN THE WALL?

Mauro, D., Vecellio, M., Schmid, E., Bergot, A. S., Forte, G., Stingo, A., Salzillo, A., Pastore, A., Aretini, P., Ciancio, A., Pantano, I., Saccone, G., Zullo, F., Montecucco, C., Rizzo, A., Schett, G., Thomas, R., Zaiss, M. M. and Ciccia, F. (2024). POS0303 CROSSING THE BARRIERS: DYSBIOSIS AND SUBCLINICAL UTERINE INFLAMMATION IN THE PATHOGENESIS OF AxSpA IN FEMALES. ANOTHER BREAK IN THE WALL?. BMJ Publishing Group Ltd and European League Against Rheumatism. doi: 10.1136/annrheumdis-2024-eular.4993

POS0303 CROSSING THE BARRIERS: DYSBIOSIS AND SUBCLINICAL UTERINE INFLAMMATION IN THE PATHOGENESIS OF AxSpA IN FEMALES. ANOTHER BREAK IN THE WALL?

2024

Conference Publication

POS0313 INTESTINAL NEUROINFLAMMATION IN SPA IS CORRELATED WITH DYSBIOSIS

Forte, G., Mauro, D., Bergot, A. S., Cameron, A., Ciancio, A., Scalise, G., Salzillo, A., Pantano, I., Panarese, I., Vespere, G., De Luca, L., Desena, G., Napolitano, V., Franco, R., Provitera, V., Thomas, R. and Ciccia, F. (2024). POS0313 INTESTINAL NEUROINFLAMMATION IN SPA IS CORRELATED WITH DYSBIOSIS. BMJ Publishing Group Ltd and European League Against Rheumatism. doi: 10.1136/annrheumdis-2024-eular.5422

POS0313 INTESTINAL NEUROINFLAMMATION IN SPA IS CORRELATED WITH DYSBIOSIS

2024

Conference Publication

Type 3 cytokine blockade in translocation of instestinal bacteria in spondyloarthropathy

Cai, B., Giri, R., Benham, H., Rehaume, L., Strutton, G., Bergot, A. S. and Thomas, R. (2024). Type 3 cytokine blockade in translocation of instestinal bacteria in spondyloarthropathy. EULAR 2024 European Congress of Rheumatology, Vienna, Austria, 12-15 June 2024. London, United Kingdom: BMJ Group. doi: 10.1136/annrheumdis-2024-eular.2408

Type 3 cytokine blockade in translocation of instestinal bacteria in spondyloarthropathy

2023

Conference Publication

Goblet cell specific anti-apoptotic role of interleukin-24 in spondyloarthritis-associated ileitis

Cameron, A., Giri, R., Begun, J., Wells, T., Bergot, A. S. and Thomas, R. (2023). Goblet cell specific anti-apoptotic role of interleukin-24 in spondyloarthritis-associated ileitis. EULAR 2023 European Congress of Rheumatology, Milan, Italy, 31 May-3 June 2023. London, United Kingdom: BMJ Group. doi: 10.1136/annrheumdis-2023-eular.1346

Goblet cell specific anti-apoptotic role of interleukin-24 in spondyloarthritis-associated ileitis

2023

Conference Publication

The interplay of IL-23, probiotic and pathobiont bacteria in the pathogenesis of ileitis and spondyloarthritis in the SKG mouse model

Bergot, Anne-Sophie, Cai, Benjamin, Giri, Rabina, Cameron, Amy, Duggan, Emily, Lim, Kai, Rehaume, Linda, Morrison, Mark, Begun, Jakob and Thomas, Ranjeny (2023). The interplay of IL-23, probiotic and pathobiont bacteria in the pathogenesis of ileitis and spondyloarthritis in the SKG mouse model. 2023 Australian Rheumatology Association (ARA) 63rd Annual Scientific Meeting, Hobart, TAS, Australia, 6–9 May 2023. Hoboken, NJ, United States: Wiley.

The interplay of IL-23, probiotic and pathobiont bacteria in the pathogenesis of ileitis and spondyloarthritis in the SKG mouse model

2023

Journal Article

Genetically encoded Runx3 and CD4+ intestinal epithelial lymphocyte deficiencies link SKG mouse and human predisposition to spondyloarthropathy

Bhuyan, Zaied Ahmed, Rahman, M. Arifur, Maradana, Muralidhara Rao, Mehdi, Ahmed M., Bergot, Anne-Sophie, Simone, Davide, El-Kurdi, Marya, Garrido-Mesa, Jose, Cai, Cheng Bang Benjamin, Cameron, Amy J., Hanson, Aimee L., Nel, Hendrik J., Kenna, Tony, Leo, Paul, Rehaume, Linda, Brown, Matthew A., Ciccia, Francesco and Thomas, Ranjeny (2023). Genetically encoded Runx3 and CD4+ intestinal epithelial lymphocyte deficiencies link SKG mouse and human predisposition to spondyloarthropathy. Clinical Immunology, 247 109220, 1-14. doi: 10.1016/j.clim.2022.109220

Genetically encoded Runx3 and CD4+ intestinal epithelial lymphocyte deficiencies link SKG mouse and human predisposition to spondyloarthropathy

2023

Journal Article

Islet‐specific CD8+ T cells gain effector function in the gut lymphoid tissues via bystander activation not molecular mimicry

Okada, Mirei, Zhang, Vivian, Loaiza Naranjo, Jeniffer D., Tillett, Bree J., Wong, F. Susan, Steptoe, Raymond J., Bergot, Anne‐Sophie and Hamilton‐Williams, Emma E (2023). Islet‐specific CD8+ T cells gain effector function in the gut lymphoid tissues via bystander activation not molecular mimicry. Immunology and Cell Biology, 101 (1), 36-48. doi: 10.1111/imcb.12593

Islet‐specific CD8+ T cells gain effector function in the gut lymphoid tissues via bystander activation not molecular mimicry

2022

Journal Article

Secreted NF-κB suppressive microbial metabolites modulate gut inflammation

Giri, Rabina, Hoedt, Emily C., Khushi, Shamsunnahar, Salim, Angela A., Bergot, Anne-Sophie, Schreiber, Veronika, Thomas, Ranjeny, McGuckin, Michael A., Florin, Timothy H., Morrison, Mark, Capon, Robert J., Ó Cuív, Páraic and Begun, Jakob (2022). Secreted NF-κB suppressive microbial metabolites modulate gut inflammation. Cell Reports, 39 (2) 110646, 110646. doi: 10.1016/j.celrep.2022.110646

Secreted NF-κB suppressive microbial metabolites modulate gut inflammation

2022

Journal Article

Tolerance induction by liposomes targeting a single CD8 epitope IGRP in a model of type 1 diabetes is impeded by co-targeting a CD4 islet epitope

Buckle, Irina, Loaiza Naranjo, Jeniffer D., Bergot, Anne-Sophie, Zhang, Vivian, Talekar, Meghna, Steptoe, Raymond J., Thomas, Ranjeny and Hamilton-Williams, Emma E. (2022). Tolerance induction by liposomes targeting a single CD8 epitope IGRP in a model of type 1 diabetes is impeded by co-targeting a CD4 islet epitope. Immunology and Cell Biology, 100 (1), 33-48. doi: 10.1111/imcb.12506

Tolerance induction by liposomes targeting a single CD8 epitope IGRP in a model of type 1 diabetes is impeded by co-targeting a CD4 islet epitope

2021

Journal Article

Inflammasome activation in ankylosing spondylitis is associated to gut dysbiosis

Guggino, Giuliana, Mauro, Daniele, Rizzo, Aroldo, Alessandro, Riccardo, Raimondo, Stefania, Bergot, Anne-Sophie, Rahman, M Arifur, Ellis, Jonathan J., Milling, Simon, Lories, Rik, Elewaut, Dirk, Brown, Matthew A., Thomas, Ranjeny and Ciccia, Francesco (2021). Inflammasome activation in ankylosing spondylitis is associated to gut dysbiosis. Arthritis and Rheumatology, 73 (7) art.41644, 1189-1199. doi: 10.1002/art.41644

Inflammasome activation in ankylosing spondylitis is associated to gut dysbiosis

2021

Journal Article

CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes

Narsale, Aditi, Lam, Breanna, Moya, Rosa, Lu, TingTing, Mandelli, Alessandra, Gotuzzo, Irene, Pessina, Benedetta, Giamporcaro, Gianmaria, Geoffrey, Rhonda, Buchanan, Kerry, Harris, Mark, Bergot, Anne-Sophie, Thomas, Ranjeny, Hessner, Martin J., Battaglia, Manuela, Serti, Elisavet and Davies, Joanna D. (2021). CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes. JCI Insight, 6 (2) e136114. doi: 10.1172/jci.insight.136114

CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes

2021

Journal Article

Proinsulin‐specific T‐cell responses correlate with estimated c‐peptide and predict partial remission duration in type 1 diabetes

Musthaffa, Yassmin, Hamilton‐Williams, Emma E, Nel, Hendrik J., Bergot, Anne‐Sophie, Mehdi, Ahmed M., Harris, Mark and Thomas, Ranjeny (2021). Proinsulin‐specific T‐cell responses correlate with estimated c‐peptide and predict partial remission duration in type 1 diabetes. Clinical & Translational Immunology, 10 (7) e1315, e1315. doi: 10.1002/cti2.1315

Proinsulin‐specific T‐cell responses correlate with estimated c‐peptide and predict partial remission duration in type 1 diabetes

2020

Journal Article

A Question of Tolerance—Antigen-Specific Immunotherapy for Type 1 Diabetes

Loaiza Naranjo, Jeniffer D., Bergot, Anne-Sophie, Buckle, Irina and Hamilton-Williams, Emma E. (2020). A Question of Tolerance—Antigen-Specific Immunotherapy for Type 1 Diabetes. Current Diabetes Reports, 20 (12) 70, 70. doi: 10.1007/s11892-020-01363-3

A Question of Tolerance—Antigen-Specific Immunotherapy for Type 1 Diabetes

2020

Conference Publication

Curdlan-induced Villous Permeability, Luminal Pathobiont Translocation to the Ileal Crypts, Ileitis and Arthritis Are Mitigated by Clostridia in Colonised Germ-free SKG Mice

Bergot, Anne-Sophie, Giri, Rabina, Cameron, Amy, Duggan, Emily, Loayza, Jeimy Jimenez, Morrison, Mark, Rehaume, Linda, Begun, Jakob and Thomas, Ranjeny (2020). Curdlan-induced Villous Permeability, Luminal Pathobiont Translocation to the Ileal Crypts, Ileitis and Arthritis Are Mitigated by Clostridia in Colonised Germ-free SKG Mice. Annual Meeting of the American-College-of-Rheumatology (ACR), Electr Network, Nov 05-09, 2020. HOBOKEN: WILEY.

Curdlan-induced Villous Permeability, Luminal Pathobiont Translocation to the Ileal Crypts, Ileitis and Arthritis Are Mitigated by Clostridia in Colonised Germ-free SKG Mice

2020

Journal Article

The microbiome and rheumatoid arthritis

Bergot, Anne-Sophie, Giri, Rabina and Thomas, Ranjeny (2020). The microbiome and rheumatoid arthritis. Best Practice and Research: Clinical Rheumatology, 33 (6) 101497, 101497. doi: 10.1016/j.berh.2020.101497

The microbiome and rheumatoid arthritis

2020

Journal Article

Regulatory T cells induced by single-peptide liposome immunotherapy suppress islet-Specific T cell responses to multiple antigens and protect from autoimmune diabetes

Bergot, Anne-Sophie, Buckle, Irina, Cikaluru, Sumana, Naranjo, Jennifer Loaiza, Wright, Casey Maree, Zheng, Guoliang, Talekar, Meghna, Hamilton-Williams, Emma E. and Thomas, Ranjeny (2020). Regulatory T cells induced by single-peptide liposome immunotherapy suppress islet-Specific T cell responses to multiple antigens and protect from autoimmune diabetes. Journal of Immunology, 204 (7), ji1901128-1797. doi: 10.4049/jimmunol.1901128

Regulatory T cells induced by single-peptide liposome immunotherapy suppress islet-Specific T cell responses to multiple antigens and protect from autoimmune diabetes

2019

Conference Publication

CD4+CD25+CD127HI cells correlate with length of remission in type 1 diabetes: validated in a multi-site study

Narsale, A., Moya, R., Robertson, H., Payne, D., Lu, T. T., Geoffery, R., Buchanan, K., Harris, M., Bergot, A. S., Thomas, R., Hessner, M., Battaglia, M., Serti, E. and Davies, J. (2019). CD4+CD25+CD127HI cells correlate with length of remission in type 1 diabetes: validated in a multi-site study. International Conference on Lymphocyte Engineering (ICLE), London, United Kingdom, 13-15 September 2019. New Rochelle, NY United States: Mary Ann Liebert. doi: 10.1089/hum.2019.29091.abstracts

CD4+CD25+CD127HI cells correlate with length of remission in type 1 diabetes: validated in a multi-site study

2018

Conference Publication

Antigen-Specific CD4 regulation by Liposomes encapsulating calcitriol and ChgA mimotope in NOD mice

Bergot, A. S., Buckle,, Wright, C., Talekar, M., Hamilton-Williams, E. and Thomas, R. (2018). Antigen-Specific CD4 regulation by Liposomes encapsulating calcitriol and ChgA mimotope in NOD mice. 15th International Symposium on Dendritic Cells (DC), Aachen, Germany, 10-14 June 2018. Hoboken, NJ, United States: Wiley. doi: 10.1002/eji.201871000

Antigen-Specific CD4 regulation by Liposomes encapsulating calcitriol and ChgA mimotope in NOD mice

2017

Journal Article

Human papillomavirus E7 oncoprotein expression by keratinocytes alters the cytotoxic mechanisms used by CD8 T cells

Bhat, Purnima, Bergot, Anne-Sophie, Waterhouse, Nigel and Frazer, Ian Hector (2017). Human papillomavirus E7 oncoprotein expression by keratinocytes alters the cytotoxic mechanisms used by CD8 T cells. Oncotarget, 9 (5), 6015-6027. doi: 10.18632/oncotarget.23210

Human papillomavirus E7 oncoprotein expression by keratinocytes alters the cytotoxic mechanisms used by CD8 T cells

2017

Conference Publication

Antigen specific immunotherapy for autoimmune disease targeting dendritic cells

Bergot, Anne-Sophie, Talekar, Meghna, Nel, Hanno, Galea, Ryan, Harris, Mark, Hamilton-Williams, Emma and Thomas, Ranjeny (2017). Antigen specific immunotherapy for autoimmune disease targeting dendritic cells. 5th Annual Meeting of the International Cytokine and Interferon Society (ICIS), Kanazawa Japan, 29 October - 2 November 2017. London United Kingdom: Elsevier.

Antigen specific immunotherapy for autoimmune disease targeting dendritic cells