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2025 Journal Article The design, synthesis, and biological evaluation of 5,6,7,8-tetrahydropteridines as anti-inflammatory compoundsChen, Rachel M., Emming, Stefan, Cinnamon, Roseanna, Cameron, Jacob P., Schroder, Kate, Kobe, Bostjan and Robertson, Avril A. B. (2025). The design, synthesis, and biological evaluation of 5,6,7,8-tetrahydropteridines as anti-inflammatory compounds. Organic & Biomolecular Chemistry, 23 (1), 174-182. doi: 10.1039/d4ob01453g |
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2024 Journal Article Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cellsHolley, Caroline L., Monteleone, Mercedes, Fisch, Daniel, Libert, Alexandre E. S., Ju, Robert J., Choi, Joon H., Condon, Nicholas D., Emming, Stefan, Crawford, Joanna, Lawrence, Grace M. E. P., Coombs, Jared R., Lefevre, James G., Bajracharya, Rinie, Lahoud, Mireille H., Yap, Alpha S., Hamilton, Nicholas, Stehbens, Samantha J., Kagan, Jonathan C., Ariotti, Nicholas, Burgener, Sabrina S. and Schroder, Kate (2024). Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells. Nature Immunology, 26 (1) eaas8995, 1-35. doi: 10.1038/s41590-024-02024-3 |
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2024 Journal Article The septin modifier, forchlorfenuron, activates NLRP3 via a potassium-independent mitochondrial axisHolley, Caroline L., Emming, Stefan, Monteleone, Mercedes M., Mellacheruvu, Manasa, Kenney, Kirsten M., Lawrence, Grace M.E.P., Coombs, Jared R., Burgener, Sabrina S. and Schroder, Kate (2024). The septin modifier, forchlorfenuron, activates NLRP3 via a potassium-independent mitochondrial axis. Cell Chemical Biology, 31 (5), 962-972.e4. doi: 10.1016/j.chembiol.2024.04.012 |
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2024 Journal Article NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasomeCoombs, Jared R., Zamoshnikova, Alina, Holley, Caroline L., Maddugoda, Madhavi P., Teo, Daniel Eng Thiam, Chauvin, Camille, Poulin, Lionel F, Vitak, Nazarii, Ross, Connie M., Mellacheruvu, Manasa, Coll, Rebecca C., Heinz, Leonhard X., Burgener, Sabrina S., Emming, Stefan, Chamaillard, Mathias, Boucher, Dave and Schroder, Kate (2024). NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome. Science Signaling, 17 (820) abg8145, eabg8145. doi: 10.1126/scisignal.abg8145 |
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2023 Journal Article Oxidized thioredoxin 1 places a leash on <scp>NLRP1</scp> inflammasome activityYap, Jeremy KY, Emming, Stefan and Schroder, Kate (2023). Oxidized thioredoxin 1 places a leash on NLRP1 inflammasome activity. Immunology & Cell Biology, 102 (1), 5-7. doi: 10.1111/imcb.12710 |
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2023 Journal Article Reversing the mitochondrial hex that bewitches NLRP3Mellacheruvu, Manasa, Lawrence, Grace M. E. P., Emming, Stefan and Schroder, Kate (2023). Reversing the mitochondrial hex that bewitches NLRP3. Science Immunology, 8 (84) eadh2967, 1-4. doi: 10.1126/sciimmunol.adh2967 |
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2023 Journal Article Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion releaseLabzin, Larisa I., Chew, Keng Yih, Eschke, Kathrin, Wang, Xiaohui, Esposito, Tyron, Stocks, Claudia J., Rae, James, Patrick, Ralph, Mostafavi, Helen, Hill, Brittany, Yordanov, Teodor E., Holley, Caroline L., Emming, Stefan, Fritzlar, Svenja, Mordant, Francesca L., Steinfort, Daniel P., Subbarao, Kanta, Nefzger, Christian M., Lagendijk, Anne K., Gordon, Emma J., Parton, Robert G., Short, Kirsty R., Londrigan, Sarah L. and Schroder, Kate (2023). Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion release. Science Signaling, 16 (782) eabq1366, eabq1366. doi: 10.1126/scisignal.abq1366 |
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2021 Journal Article Ex vivo microRNA and gene expression profiling of human Tr1-like cells suggests a role for miR-92a and -125a in the regulation of EOMES and IL-10RDe Simone, Marco, Chirichella, Michele, Emming, Stefan, Mazzara, Saveria, Ranzani, Valeria, Gruarin, Paola, Moschetti, Giorgia, Pulvirenti, Nadia, Maglie, Stefano, Vasco, Chiara, Crosti, Maria Cristina, Rossetti, Grazisa, Pagani, Massimiliano, Abrignani, Sergio, Monticelli, Silvia and Geginat, Jens (2021). Ex vivo microRNA and gene expression profiling of human Tr1-like cells suggests a role for miR-92a and -125a in the regulation of EOMES and IL-10R. European Journal of Immunology, 51 (12), 3243-3246. doi: 10.1002/eji.202149315 |
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2020 Journal Article Vitamin D and IFN-β modulate the inflammatory gene expression program of primary human T lymphocytesBianchi, Niccolò, Emming, Stefan, Zecca, Chiara and Monticelli, Silvia (2020). Vitamin D and IFN-β modulate the inflammatory gene expression program of primary human T lymphocytes. Frontiers in Immunology, 11 566781. doi: 10.3389/fimmu.2020.566781 |
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2020 Journal Article A molecular network regulating the proinflammatory phenotype of human memory T lymphocytesEmming, Stefan, Bianchi, Niccolò, Polletti, Sara, Balestrieri, Chiara, Leoni, Cristina, Montagner, Sara, Chirichella, Michele, Delaleu, Nicolas, Natoli, Gioacchino and Monticelli, Silvia (2020). A molecular network regulating the proinflammatory phenotype of human memory T lymphocytes. Nature Immunology, 21 (4), 388-399. doi: 10.1038/s41590-020-0622-8 |
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2020 Journal Article Rebound of disease activity after fingolimod withdrawal: immunological and gene expression profilingSacco, Rosaria, Emming, Stefan, Gobbi, Claudio, Zecca, Chiara and Monticelli, Silvia (2020). Rebound of disease activity after fingolimod withdrawal: immunological and gene expression profiling. Multiple Sclerosis and Related Disorders, 40 101927, 101927. doi: 10.1016/j.msard.2020.101927 |
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2019 Journal Article Tiered DNA sensors for escalating responsesEmming, Stefan and Schroder, Kate (2019). Tiered DNA sensors for escalating responses. Science, 365 (6460), 1375-1376. doi: 10.1126/science.aay2701 |
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2018 Journal Article MicroRNAs as modulators of T cell functions in cancerEmming, Stefan, Chirichella, Michele and Monticelli, Silvia (2018). MicroRNAs as modulators of T cell functions in cancer. Cancer Letters, 430, 172-178. doi: 10.1016/j.canlet.2018.05.019 |
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2017 Journal Article Erratum: TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities (Cell Reports (2016) 15 (7)(1566#x2013;1579) (S2211124716304715) (10.1016/j.celrep.2016.04.044))Montagner, Sara, Leoni, Cristina, Emming, Stefan, Della Chiara, Giulia, Balestrieri, Chiara, Barozzi, Iros, Piccolo, Viviana, Togher, Susan, Ko, Myunggon, Rao, Anjana, Natoli, Gioacchino and Monticelli, Silvia (2017). Erratum: TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities (Cell Reports (2016) 15 (7)(1566#x2013;1579) (S2211124716304715) (10.1016/j.celrep.2016.04.044)). Cell Reports, 20 (7). doi: 10.1016/j.celrep.2017.08.011 |
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2016 Journal Article TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic ActivitiesMontagner, Sara, Leoni, Cristina, Emming, Stefan, Della Chiara, Giulia, Balestrieri, Chiara, Barozzi, Iros, Piccolo, Viviana, Togher, Susan, Ko, Myunggon, Rao, Anjana, Natoli, Gioacchino and Monticelli, Silvia (2016). TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities. Cell Reports, 15 (7), 1566-1579. doi: 10.1016/j.celrep.2016.04.044 |
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2015 Journal Article Epigenetics of T lymphocytes in health and diseaseLeoni, Cristina, Vincenzetti, Lucia, Emming, Stefan and Monticelli, Silvia (2015). Epigenetics of T lymphocytes in health and disease. Swiss Medical Weekly, 145 w14191. doi: 10.4414/smw.2015.14191 |
