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2015 Journal Article Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1Glubb, Dylan, Maranian, Mel J., Michailidou, Kyriaki, Pooley, Karen A., Meyer, Kerstin, Kar, Siddhartha, Carlebur, Saskia, O'Reilly, Martin, Betts, Joshua A., Hillman, Kristine M., Kaufmann, Susanne, Beesley, Jonathan, Canisius, Sander, Hopper, John L., Southey, Melissa C., Tsimiklis, Helen, Apicella, Carmel, Schmidt, Marjanka K., Broeks, Annegien, Hogervorst, Frans B., van der Schoot, C. Ellen, Muir, Kenneth, Lophatananon, Artitaya, Stewart-Brown, Sarah, Siriwanarangsan, Pornthep, Fasching, Peter, Ruebner, Matthias, Ekici, Arif B., Beckmann, Matthias W. ... French, Juliet D. (2015). Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1. American Journal of Human Genetics, 96 (1), 5-20. doi: 10.1016/j.ajhg.2014.11.009 |
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2014 Journal Article Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulationGhoussaini, Maya, Edwards, Stacey L., Michailidou, Kyriaki, Nord, Silje, Lari, Richard Cowper-Sal, Desai, Kinjal, Kar, Siddhartha, Hillman, Kristine M., Kaufmann, Susanne, Glubb, Dylan M., Beesley, Jonathan, Dennis, Joe, Bolla, Manjeet K., Wang, Qin, Dicks, Ed, Guo, Qi, Schmidt, Marjanka K., Shah, Mitul, Luben, Robert, Brown, Judith, Czene, Kamila, Darabi, Hatef, Eriksson, Mikael, Klevebring, Daniel, Bojesen, Stig E., Nordestgaard, Borge G., Nielsen, Sune F., Flyger, Henrik, Lambrechts, Diether ... Dunning, Alison M. (2014). Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation. Nature Communications, 5 (1) 4999, 4999.1-4999.12. doi: 10.1038/ncomms5999 |
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2014 Journal Article Discovery and functional assessment of gene variants in the vascular endothelial growth factor pathwayParé-Brunet, Laia, Glubb, Dylan, Evans, Patrick, Berenguer-Llergo, Antoni, Etheridge, Amy S., Skol, Andrew D., Di Rienzo, Anna, Duan, Shiwei, Gamazon, Eric R. and Innocenti, Federico (2014). Discovery and functional assessment of gene variants in the vascular endothelial growth factor pathway. Human Mutation, 35 (2), 227-235. doi: 10.1002/humu.22475 |
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2013 Journal Article A guide to the current web-based resources in pharmacogenomicsGlubb, Dylan M., Paugh, Steven W., Van Schaik, Ron H. N. and Innocenti, Federico (2013). A guide to the current web-based resources in pharmacogenomics. Methods in Molecular Biology, 1015, 293-310. doi: 10.1007/978-1-62703-435-7_19 |
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2013 Journal Article Architecture of pharmacogenomic associations: Structures with functional foundations or castles made of sand?Glubb, Dylan M. and Innocenti, Federico (2013). Architecture of pharmacogenomic associations: Structures with functional foundations or castles made of sand?. Pharmacogenomics, 14 (1), 1-4. doi: 10.2217/pgs.12.188 |
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2012 Journal Article Liver expression quantitative trait loci: A foundation for pharmacogenomic researchGlubb, Dylan M., Dholakia, Neepa and Innocenti, Federico (2012). Liver expression quantitative trait loci: A foundation for pharmacogenomic research. Frontiers in Genetics, 3 (AUG) Article 153. doi: 10.3389/fgene.2012.00153 |
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2012 Journal Article A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303Innocenti, Federico, Owzar, Kouros, Cox, Nancy L., Evans, Patrick, Kubo, Michiaki, Zembutsu, Hitoshi, Jiang, Chen, Hollis, Donna, Mushiroda, Taisei, Li, Liang, Friedman, Paula, Wang, Liewei, Glubb, Dylan, Hurwitz, Herbert, Giacomini, Kathleen M., McLeod, Howard L., Goldberg, Richard M., Schilsky, Richard L., Kindler, Hedy L., Nakamura, Yusuke and Ratain, Mark J. (2012). A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303. Clinical Cancer Research, 18 (2), 577-584. doi: 10.1158/1078-0432.CCR-11-1387 |
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2011 Journal Article Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancerGlubb, Dylan M., Cerri, Elisa, Giese, Alexandra, Zhang, Wei, Mirza, Osman, Thompson, Emma E., Chen, Peixian, Das, Soma, Jassem, Jacek, Rzyman, Witold, Lingen, Mark W., Salgia, Ravi, Hirsch, Fred R., Dziadziuszko, Rafal, Ballmer-Hofer, Kurt and Innocenti, Federico (2011). Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancer. Clinical Cancer Research, 17 (16), 5257-5267. doi: 10.1158/1078-0432.CCR-11-0379 |
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2011 Journal Article Mechanisms of genetic regulation in gene expression: Examples from drug metabolizing enzymes and transportersGlubb, Dylan M. and Innocenti, Federico (2011). Mechanisms of genetic regulation in gene expression: Examples from drug metabolizing enzymes and transporters. Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 3 (3), 299-313. doi: 10.1002/wsbm.125 |
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2011 Journal Article NOD2 and ATG16L1 polymorphisms affect monocyte responses in crohn's diseaseGlubb, Dylan M, Gearry, Richard B, Barclay, Murray L, Roberts, Rebecca L, Pearson, John, Keenan, Jacqui I, Mckenzie, Judy and Bentley, Robert W. (2011). NOD2 and ATG16L1 polymorphisms affect monocyte responses in crohn's disease. World Journal of Gastroenterology, 17 (23), 2829-2837. doi: 10.3748/wjg.v17.i23.2829 |
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2010 Journal Article Proteomic analysis of rat hippocampus exposed to the antidepressant paroxetineMcHugh, P. C., Rogers, G. R., Glubb, D. M., Joyce, P. R. and Kennedy, M. A. (2010). Proteomic analysis of rat hippocampus exposed to the antidepressant paroxetine. Journal of Psychopharmacology, 24 (8), 1243-1251. doi: 10.1177/0269881109102786 |
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2010 Journal Article Association of a functional polymorphism in the adrenomedullin gene (ADM) with response to paroxetineGlubb, D. M., McHugh, P. C., Deng, X., Joyce, P. R. and Kennedy, M. A. (2010). Association of a functional polymorphism in the adrenomedullin gene (ADM) with response to paroxetine. Pharmacogenomics Journal, 10 (2), 126-133. doi: 10.1038/tpj.2009.33 |
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2009 Journal Article Expression and association analyses of promoter variants of the neurogenic gene HES6, a candidate gene for mood disorder susceptibility and antidepressant responseGlubb, Dylan M., Joyce, Peter R. and Kennedy, Martin A. (2009). Expression and association analyses of promoter variants of the neurogenic gene HES6, a candidate gene for mood disorder susceptibility and antidepressant response. Neuroscience Letters, 460 (2), 185-190. doi: 10.1016/j.neulet.2009.05.065 |
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2008 Journal Article Proteomic analysis of embryonic stem cell-derived neural cells exposed to the antidepressant paroxetineMcHugh, Patrick C., Rogers, Geraldine R., Loudon, Barbara, Glubb, Dylan M., Joyce, Peter R. and Kennedy, Martin A. (2008). Proteomic analysis of embryonic stem cell-derived neural cells exposed to the antidepressant paroxetine. Journal of Neuroscience Research, 86 (2), 306-316. doi: 10.1002/jnr.21482 |
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2008 Journal Article Downregulation of Ccnd1 and Hes6 in rat hippocampus after chronic exposure to the antidepressant paroxetineMcHugh, Patrick C., Rogers, Geraldine R., Glubb, Dylan M., Allington, Melanie D., Hughes, Mark, Joyce, Peter R. and Kennedy, Martin A. (2008). Downregulation of Ccnd1 and Hes6 in rat hippocampus after chronic exposure to the antidepressant paroxetine. Acta Neuropsychiatrica, 20 (6), 307-313. doi: 10.1111/j.1601-5215.2008.00334.x |
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2002 Journal Article Detection and location of the enzymes of de novo pyrimidine biosynthesis in mammalian spermatozoaCarrey, E. A., Dietz, C., Glubb, D. M., Löffler, M., Lucocq, J. M. and Watson, P. F. (2002). Detection and location of the enzymes of de novo pyrimidine biosynthesis in mammalian spermatozoa. Reproduction, 123 (6), 757-768. doi: 10.1530/rep.0.1230757 |
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2001 Journal Article Protection of erythrocytes by the macrophage synthesized antioxidant 7,8 dihydroneopterinGieseg, S. P., Maghzal, G. and Glubb, D. (2001). Protection of erythrocytes by the macrophage synthesized antioxidant 7,8 dihydroneopterin. Free Radical Research, 34 (2), 123-136. doi: 10.1080/10715760100300121 |
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2001 Journal Article Protection of U937 cells from free radical damage by the macrophage synthesized antioxidant 7,8-dihydroneopterinGieseg, S. P., Whybrow, J., Glubb, D. and Rait, C. (2001). Protection of U937 cells from free radical damage by the macrophage synthesized antioxidant 7,8-dihydroneopterin. Free Radical Research, 35 (3), 311-318. doi: 10.1080/10715760100300841 |
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2000 Journal Article Inhibition of haemolysis by the macrophage synthesized antioxidant, 7,8- dihydroneopterinGieseg, S. P., Maghzal, G. and Glubb, D. (2000). Inhibition of haemolysis by the macrophage synthesized antioxidant, 7,8- dihydroneopterin. Redox Report, 5 (2-3), 98-100. doi: 10.1179/135100000101535645 |
