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2025 Journal Article Amyloid Targeting-Gold Nanoparticles-Assisted X-ray Therapy Rescues Islet β-Cells from Amyloid Fibrils and Restores Insulin HomeostasisForgham, Helen, Matre, Stetson Van, Karen Chung, Ka Hang, Tahir, Muhammad Sajid, Ali, Syed Aoun, Kikuchi, Kai, Kaur, Amandeep, Qiao, Ruirui, Kakinen, Aleksandr, Qamar, Ahmad Zaman, Davis, Thomas Paul and Javed, Ibrahim (2025). Amyloid Targeting-Gold Nanoparticles-Assisted X-ray Therapy Rescues Islet β-Cells from Amyloid Fibrils and Restores Insulin Homeostasis. ACS Nano, 19 (5), 5460-5474. doi: 10.1021/acsnano.4c13916 |
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2024 Journal Article Reverse engineering the Gut-Brain Axis and microbiome-metabolomics for symbiotic/pathogenic balance in neurodegenerative diseasesMunir, Muhammad Usman, Ali, Syed Aoun, Chung, Ka Hang Karen, Kakinen, Aleksandr, Javed, Ibrahim and Davis, Thomas Paul (2024). Reverse engineering the Gut-Brain Axis and microbiome-metabolomics for symbiotic/pathogenic balance in neurodegenerative diseases. Gut Microbes, 16 (1) 2422468, 1-30. doi: 10.1080/19490976.2024.2422468 |
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2024 Journal Article Brain targeting nanomedicines: pitfalls and promiseKakinen, Aleksandr, Jiang, Yuhao, Davis, Thomas, Teesalu, Tambet and Saarma, Mart (2024). Brain targeting nanomedicines: pitfalls and promise. International Journal of Nanomedicine, 19, 4857-4875. doi: 10.2147/ijn.s454553 |
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2024 Journal Article Endothelial leakiness elicited by amyloid protein aggregationLi, Yuhuan, Ni, Nengyi, Lee, Myeongsang, Wei, Wei, Andrikopoulos, Nicholas, Kakinen, Aleksandr, Davis, Thomas P., Song, Yang, Ding, Feng, Leong, David Tai and Ke, Pu Chun (2024). Endothelial leakiness elicited by amyloid protein aggregation. Nature Communications, 15 (1) 613, 1-18. doi: 10.1038/s41467-024-44814-1 |
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2023 Journal Article Alzheimer's progenitor amyloid‐β targets and dissolves microbial amyloids and impairs biofilm functionAli, Syed Aoun, Chung, Ka Hang Karen, Forgham, Helen, Olsen, William P., Kakinen, Aleksandr, Balaji, Arunpandian, Otzen, Daniel E., Davis, Thomas Paul and Javed, Ibrahim (2023). Alzheimer's progenitor amyloid‐β targets and dissolves microbial amyloids and impairs biofilm function. Advanced Science, 10 (29) 2301423, e2301423. doi: 10.1002/advs.202301423 |
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2022 Journal Article Keeping up with the COVID's—Could siRNA‐based antivirals be a part of the answer?Forgham, Helen, Kakinen, Aleksandr, Qiao, Ruirui and Davis, Thomas P. (2022). Keeping up with the COVID's—Could siRNA‐based antivirals be a part of the answer?. Exploration, 00 (6) 20220012, 20220012. doi: 10.1002/exp.20220012 |
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2022 Journal Article Graphene quantum dots obstruct the membrane axis of Alzheimer's amyloid betaTang, Huayuan, Li, Yuhuan, Kakinen, Aleksandr, Andrikopoulos, Nicholas, Sun, Yunxiang, Kwak, Eunbi, Davis, Thomas P., Ding, Feng and Ke, Pu Chun (2022). Graphene quantum dots obstruct the membrane axis of Alzheimer's amyloid beta. Physical Chemistry Chemical Physics, 24 (1), 86-97. doi: 10.1039/d1cp04246g |
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2021 Journal Article Dynamic protein corona of gold nanoparticles with an evolving morphologyNandakumar, Aparna, Wei, Wei, Siddiqui, Ghizal, Tang, Huayuan, Li, Yuhuan, Kakinen, Aleksandr, Wan, Xulin, Koppel, Kairi, Lin, Sijie, Davis, Thomas P., Leong, David T., Creek, Darren J., Ding, Feng, Song, Yang and Ke, Pu Chun (2021). Dynamic protein corona of gold nanoparticles with an evolving morphology. ACS Applied Materials and Interfaces, 13 (48), 58238-58251. doi: 10.1021/acsami.1c19824 |
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2021 Journal Article Structure dependent differential modulation of Aβ fibrillization by selenadiazole-based inhibitorsKalsoom, Umme, Alazmi, Meshari, Farrukh, Hafiz Syed Usama Bin, Chung, Ka Hang Karen, Alshammari, Nawaf, Kakinen, Aleksandr, Chotana, Ghayoor Abbas, Javed, Ibrahim, Davis, Thomas Paul and Saleem, Rahman Shah Zaib (2021). Structure dependent differential modulation of Aβ fibrillization by selenadiazole-based inhibitors. ACS Chemical Neuroscience, 12 (20), 3806-3817. doi: 10.1021/acschemneuro.1c00478 |
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2021 Journal Article A framework of paracellular transport via nanoparticles‐induced endothelial leakinessLee, Myeongsang, Ni, Nengyi, Tang, Huayuan, Li, Yuhuan, Wei, Wei, Kakinen, Aleksandr, Wan, Xulin, Davis, Thomas P., Song, Yang, Leong, David Tai, Ding, Feng and Ke, Pu Chun (2021). A framework of paracellular transport via nanoparticles‐induced endothelial leakiness. Advanced Science, 8 (21) 2102519, e2102519. doi: 10.1002/advs.202102519 |
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2021 Journal Article Inhibition of amyloid aggregation and toxicity with Janus iron oxide nanoparticlesAndrikopoulos, Nicholas, Song, Zhiyuan, Wan, Xulin, Douek, Alon M., Javed, Ibrahim, Fu, Changkui, Xing, Yanting, Xin, Fangyun, Li, Yuhuan, Kakinen, Aleksandr, Koppel, Kairi, Qiao, Ruirui, Whittaker, Andrew K., Kaslin, Jan, Davis, Thomas P., Song, Yang, Ding, Feng and Ke, Pu Chun (2021). Inhibition of amyloid aggregation and toxicity with Janus iron oxide nanoparticles. Chemistry of Materials, 33 (16) acs.chemmater.1c01947, 6484-6500. doi: 10.1021/acs.chemmater.1c01947 |
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2021 Journal Article Nanotoxicology and nanomedicine: The Yin and Yang of nano-bio interactions for the new decadeBondarenko, Olesja, Mortimer, Monika, Kahru, Anne, Feliu, Neus, Javed, Ibrahim, Kakinen, Aleksandr, Lin, Sijie, Xia, Tian, Song, Yang, Davis, Thomas P., Lynch, Iseult, Parak, Wolfgang J., Leong, David Tai, Ke, Pu Chun, Chen, Chunying and Zhao, Yuliang (2021). Nanotoxicology and nanomedicine: The Yin and Yang of nano-bio interactions for the new decade. Nano Today, 39 101184, 101184. doi: 10.1016/j.nantod.2021.101184 |
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2021 Journal Article Ultrasmall molybdenum disulfide quantum dots cage Alzheimer’s amyloid beta to restore membrane fluidityLi, Yuhuan, Tang, Huayuan, Zhu, Houjuan, Kakinen, Aleksandr, Wang, Di, Andrikopoulos, Nicholas, Sun, Yunxiang, Nandakumar, Aparna, Kwak, Eunbi, Davis, Thomas P., Leong, David Tai, Ding, Feng and Ke, Pu Chun (2021). Ultrasmall molybdenum disulfide quantum dots cage Alzheimer’s amyloid beta to restore membrane fluidity. ACS Applied Materials and Interfaces, 13 (25) acsami.1c06478, 29936-29948. doi: 10.1021/acsami.1c06478 |
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2021 Journal Article Spontaneous formation of β-sheet nano-barrels during the early aggregation of Alzheimer’s amyloid betaSun, Yunxiang, Kakinen, Aleksandr, Wan, Xulin, Moriarty, Niamh, Hunt, Cameron P.J., Li, Yuhuan, Andrikopoulos, Nicholas, Nandakumar, Aparna, Davis, Thomas P., Parish, Clare L., Song, Yang, Ke, Pu Chun and Ding, Feng (2021). Spontaneous formation of β-sheet nano-barrels during the early aggregation of Alzheimer’s amyloid beta. Nano Today, 38 101125, 101125. doi: 10.1016/j.nantod.2021.101125 |
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2021 Journal Article In vitro and in vivo models for anti-amyloidosis nanomedicinesKakinen, Aleksandr, Javed, Ibrahim, Davis, Thomas P. and Ke, Pu Chun (2021). In vitro and in vivo models for anti-amyloidosis nanomedicines. Nanoscale Horizons, 6 (2), 95-119. doi: 10.1039/d0nh00548g |
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2020 Journal Article Amyloid aggregation under the lens of liquid–liquid phase separationXing, Yanting, Nandakumar, Aparna, Kakinen, Aleksandr, Sun, Yunxiang, Davis, Thomas P., Ke, Pu Chun and Ding, Feng (2020). Amyloid aggregation under the lens of liquid–liquid phase separation. The Journal of Physical Chemistry Letters, 12 (1), 368-378. doi: 10.1021/acs.jpclett.0c02567 |
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2020 Journal Article The membrane axis of Alzheimer's nanomedicineLi, Yuhuan, Tang, Huayuan, Andrikopoulos, Nicholas, Javed, Ibrahim, Cecchetto, Luca, Nandakumar, Aparna, Kakinen, Aleksandr, Davis, Thomas P., Ding, Feng and Ke, Pu Chun (2020). The membrane axis of Alzheimer's nanomedicine. Advanced NanoBiomed Research, 1 (1) 2000040, 2000040. doi: 10.1002/anbr.202000040 |
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2020 Journal Article Human plasma protein corona of Aβ amyloid and its impact on islet amyloid polypeptide cross-seedingNandakumar, Aparna, Xing, Yanting, Aranha, Ritchlynn R., Faridi, Ava, Kakinen, Aleksandr, Javed, Ibrahim, Koppel, Kairi, Pilkington, Emily H., Purcell, Anthony Wayne, Davis, Thomas P., Faridi, Pouya, Ding, Feng and Ke, Pu Chun (2020). Human plasma protein corona of Aβ amyloid and its impact on islet amyloid polypeptide cross-seeding. Biomacromolecules, 21 (2), 988-998. doi: 10.1021/acs.biomac.9b01650 |
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2019 Journal Article Single-Molecular Heteroamyloidosis of Human Islet Amyloid PolypeptideKakinen, Aleksandr, Xing, Yanting, Hegoda Arachchi, Nuwan, Javed, Ibrahim, Feng, Lei, Faridi, Ava, Douek, Alon M., Sun, Yunxiang, Kaslin, Jan, Davis, Thomas P., Higgins, Michael J., Ding, Feng and Ke, Pu Chun (2019). Single-Molecular Heteroamyloidosis of Human Islet Amyloid Polypeptide. Nano Letters, 19 (9), 6535-6546. doi: 10.1021/acs.nanolett.9b02771 |
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2019 Journal Article Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategyJaved, Ibrahim, Peng, Guotao, Xing, Yanting, Yu, Tianyu, Zhao, Mei, Kakinen, Aleksandr, Faridi, Ava, Parish, Clare L., Ding, Feng, Davis, Thomas P., Ke, Pu Chun and Lin, Sijie (2019). Inhibition of amyloid beta toxicity in zebrafish with a chaperone-gold nanoparticle dual strategy. Nature Communications, 10 (1) 3780, 3780. doi: 10.1038/s41467-019-11762-0 |
