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2023

Conference Publication

Iron restricted erythropoiesis under hepcidin mimetic treatment (PN23114) improved disease parameters in a mouse model for sickle cell disease

Taranath, Roopa, Zhao, Li, Bourne, Gregory, Bhatt, Ramesh R., Plevy, Scott, Liu, David Y. and Bhandari, Ashok (2023). Iron restricted erythropoiesis under hepcidin mimetic treatment (PN23114) improved disease parameters in a mouse model for sickle cell disease. 65th Annual Meeting of the American Society of Hematology (ASH), San Diego, CA, United States, 9-12 December 2023. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2023-182472

Iron restricted erythropoiesis under hepcidin mimetic treatment (PN23114) improved disease parameters in a mouse model for sickle cell disease

2020

Conference Publication

Hepcidin peptidomimetics - oral efficacy in pre-clinical disease model of iron overload

Taranath, Roopa, Bourne, Gregory, Zhang, Jie, Frederick, Brian, Tran, Tran T., Bhandari, Ashok, Vengalam, Jayanthi, McMahon, Jaimee, Huie, Keith, Ledet, Grace A., Zhao, Li, Tovera, James, Lee, Larry, Yang, Bo, Dion, Celino, Yuan, Lucy, Zemede, Genet, Nguyen, Michelle, Masjedizadeh, Mohammad, Cheng, Xiaoli, Mattheakis, Larry, Liu, David and Smythe, Mark L. (2020). Hepcidin peptidomimetics - oral efficacy in pre-clinical disease model of iron overload. 62nd Annual Meeting of the American Society of Hematology (ASH), Virtual, 5-8 December 2020. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2020-141720

Hepcidin peptidomimetics - oral efficacy in pre-clinical disease model of iron overload

2018

Conference Publication

Oral delivery of peptides with dual mu/delta opioid receptor agonist activities are superior to eluxadoline in preclinical models of IBS-D

Mattheakis, Larry, Anandan, Sampath-Kumar, Zhao, Li, Zerangue, Noa, Zhang, Jenny, Bourne, Greg T., Shah, Shairaz, Foulke, Matthew, Vinh Tran,, Tovera, James, Bai, Lu, Taranath, Roopa, Stephenson, Adam, Annamalai, Thamil, Bhandari, Ashok and Liu, David Y. (2018). Oral delivery of peptides with dual mu/delta opioid receptor agonist activities are superior to eluxadoline in preclinical models of IBS-D. Annual Meeting of the American Society for Gastrointestinal Endoscopy / Digestive Disease Week, Washington, DC, United States, 2-5 June 2018. Philadelphia, PA, United States: Elsevier.

Oral delivery of peptides with dual mu/delta opioid receptor agonist activities are superior to eluxadoline in preclinical models of IBS-D

2017

Conference Publication

Hepcidin Mimetic Ptg-300 for Treatment of Ineffective Erythropoiesis and Iron Overload

Bourne, Gregory, Zhao, Li, Bhandari, Ashok, Frederick, Brian, McMahon, Jaimee, Tran, Vinh, Zhang, Jenny, Stephenson, Adam, Tovera, James, Bai, Lu, Annamalai, Thamil, Patel, Dinesh, Smythe, Mark and Liu, David (2017). Hepcidin Mimetic Ptg-300 for Treatment of Ineffective Erythropoiesis and Iron Overload. Seventh Congress of the International BioIron Society (IBIS)Biennial World Meeting (BioIron 2017), Los Angeles, CA, United States, 7 - 11 May 2017. Hoboken, NJ United States: Wiley.

Hepcidin Mimetic Ptg-300 for Treatment of Ineffective Erythropoiesis and Iron Overload

2016

Conference Publication

Discovery of novel and potent orally stable peptide antagonists of the human IL-23 receptor and their pre-clinical POC in rat colitis models

Bhandari, Ashok, Cheng, Xiaoli, Bourne, Greg T., Frederick, Brian, Zhang, Jenny, McMahon, Jaimee, Celino, Herodion, Zemede, Genet, Vinh Tran,, Tovera, James, Dogra, Mridula, Bai, Lu, Zhao, Li, Lister, Harriet, Shah, Shairaz, Annamalai, Thamil, Mattheakis, Larry, Patel, Dinesh and Liu, David (2016). Discovery of novel and potent orally stable peptide antagonists of the human IL-23 receptor and their pre-clinical POC in rat colitis models. Digestive Disease Week (DDW), San Diego, CA, United States, 20-24 May 2016. Philadelphia, PA, United States: Elsevier. doi: 10.1016/s0016-5085(16)30739-9

Discovery of novel and potent orally stable peptide antagonists of the human IL-23 receptor and their pre-clinical POC in rat colitis models

2016

Conference Publication

Novel hepcidin mimetics

Bourne, Greg, Smythe, Mark, Frederick, Brian, Scott, Sonya, Vink, Simone, Fog, Jacob Ulrik, Tofteng-Shelton, Pernille and Madala, Praveen (2016). Novel hepcidin mimetics. 6th Meeting of the International BioIron Society, Hangzhou, China, 6-10 September 2015. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/ajh.24277

Novel hepcidin mimetics

2013

Conference Publication

Replacement of peptide amide bond by amide nitroxide to enhance precision of distance distributions by DEER EPR

Marshall, Garland R., Kulis, Christina, Bourne, Gregory T., Hindson, Christopher M., Hanson, Graeme R. and Smythe, Mark L. (2013). Replacement of peptide amide bond by amide nitroxide to enhance precision of distance distributions by DEER EPR. 23rd American Peptide Symposium, Waikoloa, HI, United States, 22-27 June 2013. Hoboken, NJ, United States: John Wiley & Sons.

Replacement of peptide amide bond by amide nitroxide to enhance precision of distance distributions by DEER EPR

2010

Conference Publication

Design, synthesis and evaluation of inhibitors targeting the SHP-1 catalytic domain

Kulis, C., Bourne, G., Kellie, S. and Smythe, M. (2010). Design, synthesis and evaluation of inhibitors targeting the SHP-1 catalytic domain. EPS 2010: The 31st European Peptide Symposium, Copenhagen, Denmark, 5-9 September 2010. West Sussex, United Kingdom: John Wiley & Sons. doi: 10.1002/psc.1303

Design, synthesis and evaluation of inhibitors targeting the SHP-1 catalytic domain

2004

Conference Publication

From Omega-Conotoxins to Macrocycle Mimetics

Schroeder, CI, Nielsen, KJ, Adams, DA, Loughnan, M, Thomas, L, Bourne, GT, Smythe, ML, Alewood, PF, Craik, DJ and Lewis, RJ (2004). From Omega-Conotoxins to Macrocycle Mimetics. CHICHESTER: JOHN WILEY & SONS LTD.

From Omega-Conotoxins to Macrocycle Mimetics

2001

Conference Publication

Privilege structures: New strategies for the synthesis of cyclic tetrapepties

Meutermans, W., Golding, S., Campitelli, M.R., Horton, D., Bourne, G. T. and Smythe, M. L. (2001). Privilege structures: New strategies for the synthesis of cyclic tetrapepties. 17th AFS, San Diego, 9-15th June, 2001. USA: American Peptide Society.

Privilege structures: New strategies for the synthesis of cyclic tetrapepties

2001

Conference Publication

Incorporation of a cis-amide bond isostere in the synthesis of cyclic tetrapeptides

Bourne, G. T., Cassidy, P.J., Meutermans, W., Campitelli, M.R. and Smythe, M.L. (2001). Incorporation of a cis-amide bond isostere in the synthesis of cyclic tetrapeptides. Peptides: The wave of the future, San Diego, 9-14/6/01. USA: American Peptide Society.

Incorporation of a cis-amide bond isostere in the synthesis of cyclic tetrapeptides

2001

Conference Publication

The use of a novel safety catch linker for BOC-based assembly of cyclic peptide libraries

Golding, S.W., Bourne, G.T., Meutermans, W.D.F., Jones, A. and Smythe, M.L. (2001). The use of a novel safety catch linker for BOC-based assembly of cyclic peptide libraries. 17th Australian Peptide Conference, San Diego, Calafornia, 9-14 June, 2001. USA: American Peptide Society.

The use of a novel safety catch linker for BOC-based assembly of cyclic peptide libraries

2000

Conference Publication

An evaluation of a novel safety catch linker for the development of cyclic peptide libraries

Bourne, G. T., McGeary, R. P., Golding, S., Meutermans, W., Alewood, P. F. and Smythe, M. L. (2000). An evaluation of a novel safety catch linker for the development of cyclic peptide libraries. 16th American Peptide Symposium, Minneapolis, MN United States, 26 June - 1 July 1999.

An evaluation of a novel safety catch linker for the development of cyclic peptide libraries

2000

Conference Publication

The side-chain classification of loops from high resolution protein crystal structures

Tran, T. T., Bourne, G. T., Golding, S., Meutermans, W. and Smythe, M. L. (2000). The side-chain classification of loops from high resolution protein crystal structures. 16th American Peptide symposium, Minneapolis, MN United States, 26 June - 1 July 1999. Dordrecht, Netherlands: Kluwer. doi: 10.1007/0-306-46881-6_130

The side-chain classification of loops from high resolution protein crystal structures

2000

Conference Publication

Synthesis of small cyclic peptides: An auxiliary approach to address the difficult cyclization problem

Meutermans, W., Golding, S., Bourne, G. T., Miranda, L. P., Dooley, M., Alewood, P. F. and Smythe, M. L. (2000). Synthesis of small cyclic peptides: An auxiliary approach to address the difficult cyclization problem. 16th American Peptide Symposium, Minneapolis, MN United States, 26 June - 1 July 1999. Dordrecht, Netherlands: Kluwer. doi: 10.1007/0-306-46881-6_75

Synthesis of small cyclic peptides: An auxiliary approach to address the difficult cyclization problem