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2024 Journal Article J-2156, a small molecule somatostatin type 4 receptor agonist, alleviated hindpaw hypersensitivity in the streptozotocin-induced rat model of painful diabetic neuropathy but with a 2-fold decrease in potency at an advanced stage in the model, mimicking morphineKuo, A., Imam, M. Z., Li, R., Lin, L., Raboczyj, A., Bohmer, A. E., Nicholson, J. R., Corradini, L. and Smith, M. T. (2024). J-2156, a small molecule somatostatin type 4 receptor agonist, alleviated hindpaw hypersensitivity in the streptozotocin-induced rat model of painful diabetic neuropathy but with a 2-fold decrease in potency at an advanced stage in the model, mimicking morphine. Frontiers in Pharmacology, 15 1346801. doi: 10.3389/fphar.2024.1346801 |
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2023 Journal Article In Vitro Assessment of the Metabolic Stability of Two Novel Endomorphin-2 Analogs, CYX-5 and CYX-6, in Rat Liver MicrosomesImam, Mohammad Zafar, Ghassabian, Sussan, Kuo, Andy, Cai, Yunxin, Qin, Yajuan, Li, Tingyou and Smith, Maree T. (2023). In Vitro Assessment of the Metabolic Stability of Two Novel Endomorphin-2 Analogs, CYX-5 and CYX-6, in Rat Liver Microsomes. European Journal of Drug Metabolism and Pharmacokinetics, 48 (4), 463-466. doi: 10.1007/s13318-023-00828-6 |
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2023 Journal Article Multitargeted opioid ligand discovery as a strategy to retain analgesia and reduce opioid-related adverse effectsSmith, Maree T., Kong, Dehui, Kuo, Andy, Imam, Mohammad Z. and Williams, Craig M. (2023). Multitargeted opioid ligand discovery as a strategy to retain analgesia and reduce opioid-related adverse effects. Journal of Medicinal Chemistry, 66 (6), 3746-3784. doi: 10.1021/acs.jmedchem.2c01695 |
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2023 Journal Article CYX-5, a G-protein biassed MOP receptor agonist, DOP receptor antagonist and KOP receptor agonist, evokes constipation but not respiratory depression relative to morphine in ratsImam, Mohammad Zafar, Kuo, Andy, Ghassabian, Sussan, Cai, Yunxin, Qin, Yajuan, Li, Tingyou and Smith, Maree T. (2023). CYX-5, a G-protein biassed MOP receptor agonist, DOP receptor antagonist and KOP receptor agonist, evokes constipation but not respiratory depression relative to morphine in rats. Pharmacological Reports, 75 (3), 634-646. doi: 10.1007/s43440-023-00446-8 |
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2022 Journal Article Analgesic opioid ligand discovery based on nonmorphinan scaffolds derived from natural sourcesSmith, Maree T., Kong, Dehui, Kuo, Andy, Imam, Mohammad Z. and Williams, Craig M. (2022). Analgesic opioid ligand discovery based on nonmorphinan scaffolds derived from natural sources. Journal of Medicinal Chemistry, 65 (3) acs.jmedchem.0c01915, 1612-1661. doi: 10.1021/acs.jmedchem.0c01915 |
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2020 Journal Article Assessment of the anti-allodynic efficacy of a glycine transporter 2 inhibitor relative to pregabalin and duloxetine in a rat model of prostate cancer-induced bone painImam, Mohammad Zafar, Kuo, Andy, Nicholson, Janet R., Corradini, Laura and Smith, Maree T. (2020). Assessment of the anti-allodynic efficacy of a glycine transporter 2 inhibitor relative to pregabalin and duloxetine in a rat model of prostate cancer-induced bone pain. Pharmacological Reports, 72 (5), 1418-1425. doi: 10.1007/s43440-020-00145-8 |
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2020 Journal Article Intracerebroventricular administration of CYX-6, a potent μ-opioid receptor agonist, a δ- and κ-opioid receptor antagonist and a biased ligand at μ, δ & κ-opioid receptors, evokes antinociception with minimal constipation and respiratory depression in rats in contrast to morphineImam, Mohammad Zafar, Kuo, Andy, Ghassabian, Sussan, Cai, Yunxin, Qin, Yajuan, Li, Tingyou and Smith, Maree T. (2020). Intracerebroventricular administration of CYX-6, a potent μ-opioid receptor agonist, a δ- and κ-opioid receptor antagonist and a biased ligand at μ, δ & κ-opioid receptors, evokes antinociception with minimal constipation and respiratory depression in rats in contrast to morphine. European Journal of Pharmacology, 871 172918, 172918. doi: 10.1016/j.ejphar.2020.172918 |
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2020 Journal Article Countering opioid-induced respiratory depression by non-opioids that are respiratory stimulantsImam, Mohammad Zafar, Kuo, Andy and Smith, Maree T. (2020). Countering opioid-induced respiratory depression by non-opioids that are respiratory stimulants. F1000Research, 9 91, 91. doi: 10.12688/f1000research.21738.1 |
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2018 Journal Article Trichosanthes dioica Roxb.: a vegetable with diverse pharmacological propertiesKhandaker, Mahia, Akter, Saleha and Imam, Mohammad Zafar (2018). Trichosanthes dioica Roxb.: a vegetable with diverse pharmacological properties. Food Science and Human Wellness, 7 (1), 34-48. doi: 10.1016/j.fshw.2017.12.005 |
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2017 Journal Article Progress in understanding mechanisms of opioid-induced gastrointestinal adverse effects and respiratory depressionImam, Mohammad Zafar, Kuo, Andy, Ghassabian, Sussan and Smith, Maree T. (2017). Progress in understanding mechanisms of opioid-induced gastrointestinal adverse effects and respiratory depression. Neuropharmacology, 131, 238-255. doi: 10.1016/j.neuropharm.2017.12.032 |
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2017 Journal Article Antinociceptive activity of methanol extract of leaves of Solanum sisymbriifolium in heat and chemical-induced painNasrin, Tania, Khandaker, Mahia, Akter, Saleha and Imam, Mohammad Zafar (2017). Antinociceptive activity of methanol extract of leaves of Solanum sisymbriifolium in heat and chemical-induced pain. Journal of Applied Pharmaceutical Science, 7 (11), 142-146. doi: 10.7324/JAPS.2017.71121 |
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2015 Journal Article Antinociceptive and neuropharmacological activities of methanol extract of Phoenix sylvestris fruit pulpShajib, Md. Shafiullah, Akter, Saleha, Ahmed, Tajnin and Imam, Mohammad Zafar (2015). Antinociceptive and neuropharmacological activities of methanol extract of Phoenix sylvestris fruit pulp. Frontiers in Pharmacology, 6 (OCT) 212, 1-12. doi: 10.3389/fphar.2015.00212 |
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2015 Journal Article Antinociceptive effect of methanol extract of leaves of Persicaria hydropiper in miceKhatun, Ambia, Imam, Mohammad Zafar and Rana, Md Sohel (2015). Antinociceptive effect of methanol extract of leaves of Persicaria hydropiper in mice. BMC Complementary and Alternative Medicine, 15 (1) 63, 63. doi: 10.1186/s12906-015-0558-y |
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2015 Journal Article Evaluation of antinociceptive activity of ethanol extract of leaves of Adenanthera pavoninaMoniruzzaman, Md., Khatun, Ambia and Imam, Mohammad Zafar (2015). Evaluation of antinociceptive activity of ethanol extract of leaves of Adenanthera pavonina. Evidence-Based Complementary and Alternative Medicine, 2015 412497, 1-8. doi: 10.1155/2015/412497 |
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2014 Journal Article Evaluation of antinociceptive effect of methanolic extract of leaves of Crataeva nurvala Buch.-Ham.Moniruzzaman, Md and Imam, Mohammad Zafar (2014). Evaluation of antinociceptive effect of methanolic extract of leaves of Crataeva nurvala Buch.-Ham.. BMC Complementary and Alternative Medicine, 14 (1) 354, 1-7. doi: 10.1186/1472-6882-14-354 |
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2014 Journal Article Antinociceptive effect of ethanol extract of leaves of Lannea coromandelicaImam, Mohammad Zafar and Moniruzzaman, Md (2014). Antinociceptive effect of ethanol extract of leaves of Lannea coromandelica. Journal of Ethnopharmacology, 154 (1), 109-115. doi: 10.1016/j.jep.2014.03.032 |
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2014 Journal Article Evaluation of antinociceptive activity of hydromethanol extract of Cyperus rotundus in miceImam, Mohammad Zafar and Sumi, Chandra Datta (2014). Evaluation of antinociceptive activity of hydromethanol extract of Cyperus rotundus in mice. BMC Complementary and Alternative Medicine, 14 83. doi: 10.1186/1472-6882-14-83 |
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2013 Journal Article Awareness regarding the importance of calcium and vitamin D among the undergraduate pharmacy students in BangladeshUddin, Riaz, Huda, Naz Hasan, Jhanker, Yeakuty Marzan, Jesmeen, Tasbira, Imam, Mohammad Zafar and Akter, Saleha (2013). Awareness regarding the importance of calcium and vitamin D among the undergraduate pharmacy students in Bangladesh. BMC Research Notes, 6 (1) 134. doi: 10.1186/1756-0500-6-134 |
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2012 Journal Article Antinociceptive, antidiarrheal, and neuropharmacological activities of Barringtonia acutangulaImam, Mohammad Zafar, Sultana, Shamima and Akter, Saleha (2012). Antinociceptive, antidiarrheal, and neuropharmacological activities of Barringtonia acutangula. Pharmaceutical Biology, 50 (9), 1078-1084. doi: 10.3109/13880209.2012.656850 |
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2012 Journal Article Antinociceptive activity of methanol extract of flowers of Impatiens balsaminaImam, Mohammad Zafar, Nahar, Nazmun, Akter, Saleha and Rana, Md. Sohel (2012). Antinociceptive activity of methanol extract of flowers of Impatiens balsamina. Journal of Ethnopharmacology, 142 (3), 804-810. doi: 10.1016/j.jep.2012.06.004 |
