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2023 Journal Article Ryanodine receptor activity and store‐operated Ca <sup>2+</sup> entry: critical regulators of Ca <sup>2+</sup> content and function in skeletal musclePearce, Luke, Meizoso‐Huesca, Aldo, Seng, Crystal, Lamboley, Cedric R., Singh, Daniel P. and Launikonis, Bradley S. (2023). Ryanodine receptor activity and store‐operated Ca 2+ entry: critical regulators of Ca 2+ content and function in skeletal muscle. The Journal of Physiology, 601 (19), 4183-4202. doi: 10.1113/jp279512 |
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2023 Journal Article Evolutionary isolation of ryanodine receptor isoform 1 for muscle-based thermogenesis in mammalsSingh, Daniel P., Pearce, Luke, Choi, Rocky H., Meizoso-Huesca, Aldo, Wette, Stefan G., Scott, John W., Lamboley, Cedric R., Murphy, Robyn M. and Launikonis, Bradley S. (2023). Evolutionary isolation of ryanodine receptor isoform 1 for muscle-based thermogenesis in mammals. Proceedings of the National Academy of Sciences, 120 (4) e2117503120, 1-12. doi: 10.1073/pnas.2117503120 |
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2022 Journal Article Tiny changes in cytoplasmic [Ca<sup>2+</sup>] cause large changes in mitochondrial Ca<sup>2+</sup>: what are the triggers and functional implications?Seng, Crystal, Pearce, Luke, Meizoso-Huesca, Aldo, Singh, Daniel P., Murphy, Robyn M., Lamboley, Cedric and Launikonis, Bradley S. (2022). Tiny changes in cytoplasmic [Ca2+] cause large changes in mitochondrial Ca2+: what are the triggers and functional implications?. American Journal of Physiology-Cell Physiology, 323 (4), C1285-C1289. doi: 10.1152/ajpcell.00092.2022 |
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2022 Journal Article Cardiac ryanodine receptor N-terminal region biosensors identify novel inhibitors via FRET-based high-throughput screeningZhang, Jingyan, Singh, Daniel P., Ko, Christopher Y., Nikolaienko, Roman, Wong King Yuen, Siobhan M., Schwarz, Jacob A., Treinen, Levy M., Tung, Ching-Chieh, Rožman, Kaja, Svensson, Bengt, Aldrich, Courtney C., Zima, Aleksey V., Thomas, David D., Bers, Donald M., Launikonis, Bradley S., Van Petegem, Filip and Cornea, Razvan L. (2022). Cardiac ryanodine receptor N-terminal region biosensors identify novel inhibitors via FRET-based high-throughput screening. Journal of Biological Chemistry, 298 (1) 101412, 101412. doi: 10.1016/j.jbc.2021.101412 |
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2021 Journal Article Ryanodine receptor leak triggers fiber Ca2+ redistribution to preserve force and elevate basal metabolism in skeletal muscleLamboley, Cedric R., Pearce, Luke, Seng, Crystal, Meizoso-Huesca, Aldo, Singh, Daniel P., Frankish, Barnaby P., Kaura, Vikas, Lo, Harriet P., Ferguson, Charles, Allen, Paul D., Hopkins, Philip M., Parton, Robert G., Murphy, Robyn M., van der Poel, Chris, Barclay, Christopher J. and Launikonis, Bradley S. (2021). Ryanodine receptor leak triggers fiber Ca2+ redistribution to preserve force and elevate basal metabolism in skeletal muscle. Science Advances, 7 (44) eabi7166, 1-15. doi: 10.1126/sciadv.abi7166 |
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2021 Other Outputs Ryanodine receptor calcium regulation in healthy and compromised skeletal muscleSingh, Daniel (2021). Ryanodine receptor calcium regulation in healthy and compromised skeletal muscle. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/ba6ef1f |
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2020 Journal Article Comparative label-free mass spectrometric analysis of temporal changes in the skeletal muscle proteome after impact trauma in ratsLiu, Lian, Broszczak, Daniel A., Broadbent, James A., Singh, Daniel P., Steck, Roland, Parker, Tony J. and Peake, Jonathan M. (2020). Comparative label-free mass spectrometric analysis of temporal changes in the skeletal muscle proteome after impact trauma in rats. AJP: Endocrinology and Metabolism, 318 (6), E1022-E1037. doi: 10.1152/ajpendo.00433.2019 |
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2020 Journal Article RyR1-targeted drug discovery pipeline integrating FRET-based high-throughput screening and human myofiber dynamic Ca2+ assaysRebbeck, Robyn T., Singh, Daniel P., Janicek, Kevyn A., Bers, Donald M., Thomas, David D., Launikonis, Bradley S. and Cornea, Razvan L. (2020). RyR1-targeted drug discovery pipeline integrating FRET-based high-throughput screening and human myofiber dynamic Ca2+ assays. Scientific Reports, 10 (1) 1791, 1791. doi: 10.1038/s41598-020-58461-1 |
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2019 Journal Article Mechanistic insights into store-operated Ca 2+ entry during excitation-contraction coupling in skeletal muscleKoenig, Xaver, Choi, Rocky H., Schicker, Klaus, Singh, Daniel P., Hilber, Karlheinz and Launikonis, Bradley S. (2019). Mechanistic insights into store-operated Ca 2+ entry during excitation-contraction coupling in skeletal muscle. Biochimica et Biophysica Acta, 1866 (7), 1239-1248. doi: 10.1016/j.bbamcr.2019.02.014 |
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2019 Conference Publication High-throughput screening yields allosteric inhibitors of leaky RyRs for therapeutic developmentRebbeck, Robyn T., Singh, Daniel P., Ginsburg, Kenneth S., Dong, Xiaoqiong, Thomas, David D., Bers, Donald M., Launikonis, Bradley S. and Cornea, Razvan L. (2019). High-throughput screening yields allosteric inhibitors of leaky RyRs for therapeutic development. 63rd Annual Meeting of the Biophysical Society, Baltimore, MD, United States, 2-6 March, 2019. St. Louis, MO, United States: Cell Press. doi: 10.1016/j.bpj.2018.11.2062 |
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2018 Conference Publication High-throughput screening yields allosteric inhibitors of leaky RyRS for therapeutic applicationsRebbeck, Robyn T., Dong, Xiaoqiong, Ginsburg, Kenneth S., Singh, Daniel P., Gillispie, Gregory D., Thomas, David D., Launikonis, Bradley S., Bers, Donald M. and Cornea, Razvan L. (2018). High-throughput screening yields allosteric inhibitors of leaky RyRS for therapeutic applications. 62nd Annual Meeting of the Biophysical Society, San Francisco, California, 17-21 February 2018. St. Louis, MO, United States: Cell Press. |
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2017 Journal Article Effects of topical icing on inflammation, angiogenesis, revascularization, and myofiber regeneration in skeletal muscle following contusion injurySingh, Daniel P., Lonbani, Zohreh Barani, Woodruff, Maria A., Parker, Tony J., Steck, Roland and Peake, Jonathan M. (2017). Effects of topical icing on inflammation, angiogenesis, revascularization, and myofiber regeneration in skeletal muscle following contusion injury. Frontiers in Physiology, 8, 93. doi: 10.3389/fphys.2017.00093 |
