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2025 Conference Publication Spatial transcriptomics reveals molecular determinants of mortality in thin melanomaZhou, C., Tan, S.X., Kao, Y., Claeson, M., Brown, S., Lambie, D., Whiteman, D.C., Pandeya, N., Olsen, C.M., Barbour, A., MacGregor, S., Soyer, H.P., Stark, M.S., Hayward, N., Smithers, B.M., Nguyen, Q. and Khosrotehrani, K. (2025). Spatial transcriptomics reveals molecular determinants of mortality in thin melanoma. Society for Investigative Dermatology (SID) 2025 Meeting, San Diego, CA United States, 7-10 May 2025. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2025.06.109 |
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2025 Conference Publication Epithelial-mesenchymal transition and immune exclusion underpin the natural history of primary cutaneous melanomaTan, S.X., Muller, N., Zhou, C., Vipulaguna, N., Kao, Y., Whiteman, D.C., Soyer, H.P., Stark, M.S., Nguyen, Q. and Khosrotehrani, K. (2025). Epithelial-mesenchymal transition and immune exclusion underpin the natural history of primary cutaneous melanoma. Society for Investigative Dermatology (SID) 2025 Meeting, San Diego, CA United States, 7-10 May 2025. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2025.06.953 |
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2025 Conference Publication Topical sirolimus prevents cutaneous squamous cell carcinomas by disrupting the balance between differentiation and proliferationDousset, L., Zhou, C., Kao, Y., Tan, S., Muller, N., Sormani, L., Cox, C., Soyer, H.P., Stark, M.S., Wong, H., Roy, E. and Khosrotehrani, K. (2025). Topical sirolimus prevents cutaneous squamous cell carcinomas by disrupting the balance between differentiation and proliferation. Society for Investigative Dermatology (SID) 2025 Meeting, San Diego, CA United States, 7-10 May 2025. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2025.06.777 |
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2025 Journal Article Prognostic markers could extend adjuvant immunotherapy to high-risk Stage IB/IIA melanoma: a modelling studyTan, Samuel X., Muller, Nicholas, Zhou, Chenhao, Walpole, Euan, Smithers, B. Mark, Whiteman, David C. and Khosrotehrani, Kiarash (2025). Prognostic markers could extend adjuvant immunotherapy to high-risk Stage IB/IIA melanoma: a modelling study. JAAD International, 18, 86-87. doi: 10.1016/j.jdin.2024.09.010 |
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2025 Journal Article Assessing spatial sequencing and imaging approaches to capture the molecular and pathological heterogeneity of archived cancer tissuesVo, Tuan, Prakrithi, P., Jones, Kahli, Yoon, Sohye, Lam, Pui Yeng, Kao, Yung-Ching, Ma, Ning, Tan, Samuel X., Jin, Xinnan, Zhou, Chenhao, Crawford, Joanna, Walters, Shaun, Gupta, Ishaan, Soyer, Peter H., Khosrotehrani, Kiarash, Stark, Mitchell S. and Nguyen, Quan (2025). Assessing spatial sequencing and imaging approaches to capture the molecular and pathological heterogeneity of archived cancer tissues. Journal of Pathology, 265 (3), 274-288. doi: 10.1002/path.6383 |
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2025 Journal Article Beta‐blockers and cutaneous melanoma outcomes: a systematic review and random‐effects meta‐analysisMuller, Nicholas M., Tan, Samuel X., Vipulaguna, Nisal, Zhou, Chenhao, Hughes, Maria Celia B., Soyer, H. Peter, von Schuckmann, Lena and Khosrotehrani, Kiarash (2025). Beta‐blockers and cutaneous melanoma outcomes: a systematic review and random‐effects meta‐analysis. Pigment Cell and Melanoma Research, 38 (1) e13225, 1-4. doi: 10.1111/pcmr.13225 |
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2024 Conference Publication Endothelial progenitors: Unlocking Tumor Vessel Normalization to Overcome Therapeutic Challenges in MelanomaSormani, L., Hashemi, G., Li, H., Zhou, C., Li, K., Chan, S., Tan, S.X., Nguyen, Q., Roy, E. and Khosrotehrani, K. (2024). Endothelial progenitors: Unlocking Tumor Vessel Normalization to Overcome Therapeutic Challenges in Melanoma. 53rd Annual ESDR Meeting, Lisbon, Portugal, 4-7 September 2024. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2024.10.391 |
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2024 Conference Publication Systems genetics multi-trait analysis of mouse wound healing reveals novel trait interactions with candidate genes characterised by their epidermal expression nicheMuller, N.M., Tan, S.X., Galbraith, J., Zhou, C., Roy, E. and Khosrotehrani, K. (2024). Systems genetics multi-trait analysis of mouse wound healing reveals novel trait interactions with candidate genes characterised by their epidermal expression niche. 53rd Annual ESDR Meeting, Lisbon, Portugal, 4-7 September 2024. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2024.10.546 |
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2024 Conference Publication 404 Spatial transcriptomic signatures in primary melanomas associated with sentinel node positivityMuller, N. M., Tan, S. X., Zhou, C., Kao, Y., Stark, M., Nguyen, Q. and Khosrotehrani, K. (2024). 404 Spatial transcriptomic signatures in primary melanomas associated with sentinel node positivity. 53rd Annual ESDR Meeting, 4-7 September 2024, Lisbon, Portugal. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2024.10.414 |
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2024 Journal Article Squamous cell carcinoma is associated with reduced IL34 expression, alterations in the Langerhans cell antigen‐processing‐presentation machinery and poor patient survivalDang, Thi Viet Trinh, Gillinder, Kevin R., Nguyen, Quan, Mulay, Onkar, Vo, Tuan, Mehdi, Ahmed M., Zhou, Chenhao, Brooks, Andrew J., Leggatt, Graham R., Hume, David A., Frazer, Ian H. and Chandra, Janin (2024). Squamous cell carcinoma is associated with reduced IL34 expression, alterations in the Langerhans cell antigen‐processing‐presentation machinery and poor patient survival. Clinical and Translational Immunology, 13 (12) e70018, 1-18. doi: 10.1002/cti2.70018 |
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2024 Conference Publication Epithelial cancers demonstrate IL34-associated dysfunction of Langerhans cellsDang, Thi Viet Trinh, Gillinder, Kevin R., Nguyen, Quan, Mulay, Onkar, Vo, Tuan, Mehdi, Ahmed M., Zhou, Chenhao, Brooks, Andrew J., Asplett, Kiran, Leggatt, Graham R., Hume, David A., Frazer, Ian H. and Chandra, Janin (2024). Epithelial cancers demonstrate IL34-associated dysfunction of Langerhans cells. AACR Special Conference in Cancer Research: Tumor Immunology and Immunotherapy, Boston, MA, United States, 18-21 October 2024. Philadelphia, PA, United States: American Association for Cancer Research. doi: 10.1158/2326-6074.tumimm24-a001 |
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2024 Journal Article Distinct roles of SOX9 in self-renewal of progenitors and mesenchymal transition of the endotheliumZhao, Jilai, Sormani, Laura, Jacquelin, Sebastien, Li, Haiming, Styke, Cassandra, Zhou, Chenhao, Beesley, Jonathan, Oon, Linus, Kaur, Simranpreet, Sim, Seen-Ling, Wong, Ho Yi, Dight, James, Hashemi, Ghazaleh, Shafiee, Abbas, Roy, Edwige, Patel, Jatin and Khosrotehrani, Kiarash (2024). Distinct roles of SOX9 in self-renewal of progenitors and mesenchymal transition of the endothelium. Angiogenesis, 27 (3), 1-16. doi: 10.1007/s10456-024-09927-7 |
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2024 Journal Article Lymphatic expression of the proliferation marker Ki67 is linked to sentinel node positivity, recurrence and mortality in primary cutaneous melanomaTan, Samuel X., Chong, Sharene, Rowe, Casey, Galbraith, Jack, Dight, James, Zhou, Chenhao, Malt, Maryrose, Smithers, Bernard Mark and Khosrotehrani, Kiarash (2024). Lymphatic expression of the proliferation marker Ki67 is linked to sentinel node positivity, recurrence and mortality in primary cutaneous melanoma. Experimental Dermatology, 33 (3) e15041, 1-7. doi: 10.1111/exd.15041 |
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2024 Journal Article Automated scoring of tumour infiltrating lymphocytes informs risk of death from thin melanoma: a nested case-case studyTan, Samuel X., Aung, Thazin N., Claeson, Magdalena, Acs, Balazs, Zhou, Chenhao, Brown, Susan, Lambie, Duncan, Baade, Peter D., Pandeya, Nirmala, Soyer, H. Peter, Smithers, B. Mark, Whiteman, David C., Rimm, David L. and Khosrotehrani, Kiarash (2024). Automated scoring of tumour infiltrating lymphocytes informs risk of death from thin melanoma: a nested case-case study. Journal of the American Academy of Dermatology, 90 (1), 179-182. doi: 10.1016/j.jaad.2023.09.026 |
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2023 Journal Article pSTAT5 is associated with improved survival in patients with thick or ulcerated primary cutaneous melanomaTan, Samuel X., Chong, Sharene, Rowe, Casey, Claeson, Magdalena, Dight, James, Zhou, Chenhao, Rodero, Mathieu P., Malt, Maryrose, Smithers, B. Mark, Green, Adele C. and Khosrotehrani, Kiarash (2023). pSTAT5 is associated with improved survival in patients with thick or ulcerated primary cutaneous melanoma. Melanoma Research, 33 (6), 506-513. doi: 10.1097/cmr.0000000000000915 |
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2022 Journal Article HPV status represents dominant trait driving delineation of survival-associated gene co-expression networks in head and neck cancerMehdi, Ahmed M., Zhou, Chenhao, Turrell, Gavin, Walpole, Euan, Porceddu, Sandro, Frazer, Ian H. and Chandra, Janin (2022). HPV status represents dominant trait driving delineation of survival-associated gene co-expression networks in head and neck cancer. Cancer Gene Therapy, 30 (4), 1-12. doi: 10.1038/s41417-022-00577-9 |
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2022 Other Outputs Understanding CD4+ T cell responses to HPV16 E7 antigen in a mouse model of precancerous skinZhou, Chenhao (2022). Understanding CD4+ T cell responses to HPV16 E7 antigen in a mouse model of precancerous skin. PhD Thesis, Faculty of Medicine, The University of Queensland. doi: 10.14264/84895f5 |
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2021 Journal Article A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasiaTuong, Zewen K., Lukowski, Samuel W., Nguyen, Quan H., Chandra, Janin, Zhou, Chenhao, Gillinder, Kevin, Bashaw, Abate A., Ferdinand, John R., Stewart, Benjamin J., Teoh, Siok Min, Hanson, Sarah J., Devitt, Katharina, Clatworthy, Menna R., Powell, Joseph E. and Frazer, Ian H. (2021). A model of impaired Langerhans cell maturation associated with HPV induced epithelial hyperplasia. iScience, 24 (11) 103326, 103326. doi: 10.1016/j.isci.2021.103326 |
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2021 Conference Publication Antigen-expanded t cells infiltrating new-onset rheumatoid arthritis synovial tissue are IL-6-reponsive, T-helper 2 and pro-inflammatory viral-specific clonesWehr, Pascale, Nel, Hendrik J., Zhou, Chenhao, Mehdi, Ahmed M., McGuire, Helen, Weedon, Helen, Small, Annabelle, Steptoe, Raymond, Gras, Stephanie, Wechalekar, Mihir D. and Thomas, Ranjeny (2021). Antigen-expanded t cells infiltrating new-onset rheumatoid arthritis synovial tissue are IL-6-reponsive, T-helper 2 and pro-inflammatory viral-specific clones. Australian Rheumatology Association 61st Annual Scientific Meeting, Hybrid Meeting, 21–23 May 2021. Richmond, VIC, Australia: Wiley-Blackwell. |
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2021 Journal Article Absence of Batf3 reveals a new dimension of cell state heterogeneity within conventional dendritic cellsLukowski, Samuel W., Rodahl, Inga, Kelly, Samuel, Yu, Meihua, Gotley, James, Zhou, Chenhao, Millard, Susan, Andersen, Stacey B., Christ, Angelika N., Belz, Gabrielle, Frazer, Ian H. and Chandra, Janin (2021). Absence of Batf3 reveals a new dimension of cell state heterogeneity within conventional dendritic cells. iScience, 24 (5) 102402, 1-21. doi: 10.1016/j.isci.2021.102402 |
