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2018

Journal Article

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

Gao, Qingsong, Liang, Wen-Wei, Foltz, Steven M., Mutharasu, Gnanavel, Jayasinghe, Reyka G., Cao, Song, Liao, Wen-Wei, Reynolds, Sheila M., Wyczalkowski, Matthew A., Yao, Lijun, Yu, Lihua, Sun, Sam Q., Chen, Ken, Lazar, Alexander J., Fields, Ryan C., Wendl, Michael C., Van Tine, Brian A., Vij, Ravi, Chen, Feng, Nykter, Matti, Shmulevich, Ilya, Ding, Li, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Driver Fusions and Their Implications in the Development and Treatment of Human Cancers. Cell Reports, 23 (1), 227-238.e3. doi: 10.1016/j.celrep.2018.03.050

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

2018

Journal Article

Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers

Peng, Xinxin, Chen, Zhongyuan, Farshidfar, Farshad, Xu, Xiaoyan, Lorenzi, Philip L., Wang, Yumeng, Cheng, Feixiong, Tan, Lin, Mojumdar, Kamalika, Du, Di, Ge, Zhongqi, Li, Jun, Thomas, George V., Birsoy, Kivanc, Liu, Lingxiang, Zhang, Huiwen, Zhao, Zhongming, Marchand, Calena, Weinstein, John N., Bathe, Oliver F., Liang, Han, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers. Cell Reports, 23 (1), 255-269.e4. doi: 10.1016/j.celrep.2018.03.077

Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers

2018

Journal Article

Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

Saltz, Joel, Gupta, Rajarsi, Hou, Le, Kurc, Tahsin, Singh, Pankaj, Nguyen, Vu, Samaras, Dimitris, Shroyer, Kenneth R., Zhao, Tianhao, Batiste, Rebecca, Van Arnam, John, Shmulevich, Ilya, Rao, Arvind U. K., Lazar, Alexander J., Sharma, Ashish, Thorsson, Vesteinn, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images. Cell Reports, 23 (1), 181-193.e7. doi: 10.1016/j.celrep.2018.03.086

Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

2018

Journal Article

Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

Knijnenburg, Theo A., Wang, Linghua, Zimmermann, Michael T., Chambwe, Nyasha, Gao, Galen F., Cherniack, Andrew D., Fan, Huihui, Shen, Hui, Way, Gregory P., Greene, Casey S., Liu, Yuexin, Akbani, Rehan, Feng, Bin, Donehower, Lawrence A., Miller, Chase, Shen, Yang, Karimi, Mostafa, Chen, Haoran, Kim, Pora, Jia, Peilin, Shinbrot, Eve, Zhang, Shaojun, Liu, Jianfang, Hu, Hai, Bailey, Matthew H., Yau, Christina, Wolf, Denise, Zhao, Zhongming, Weinstein, John N. ... Yang, Ian (2018). Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas. Cell Reports, 23 (1), 239-254.e6. doi: 10.1016/j.celrep.2018.03.076

Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

2018

Journal Article

Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

Ge, Zhongqi, Leighton, Jake S., Wang, Yumeng, Peng, Xinxin, Chen, Zhongyuan, Chen, Hu, Sun, Yutong, Yao, Fan, Li, Jun, Zhang, Huiwen, Liu, Jianfang, Shriver, Craig D., Hu, Hai, Piwnica-Worms, Helen, Ma, Li, Liang, Han, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types. Cell Reports, 23 (1), 213-226.e3. doi: 10.1016/j.celrep.2018.03.047

Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

2018

Journal Article

Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas

Way, Gregory P., Sanchez-Vega, Francisco, La, Konnor, Armenia, Joshua, Chatila, Walid K., Luna, Augustin, Sander, Chris, Cherniack, Andrew D., Mina, Marco, Ciriello, Giovanni, Schultz, Nikolaus, Sanchez, Yolanda, Greene, Casey S., The Cancer Genome Atlas Research Network and Yang, Ian (2018). Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas. Cell Reports, 23 (1), 172-180.e3. doi: 10.1016/j.celrep.2018.03.046

Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas

2018

Journal Article

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

Chiu, Hua-Sheng, Somvanshi, Sonal, Patel, Ektaben, Chen, Ting-Wen, Singh, Vivek P., Zorman, Barry, Patil, Sagar L., Pan, Yinghong, Chatterjee, Sujash S., Sood, Anil K., Gunaratne, Preethi H., Sumazin, Pavel, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context. Cell Reports, 23 (1), 297-312.e12. doi: 10.1016/j.celrep.2018.03.064

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

2018

Journal Article

Systematic Analysis of Splice-Site-Creating Mutations in Cancer

Jayasinghe, Reyka G., Cao, Song, Gao, Qingsong, Wendl, Michael C., Vo, Nam Sy, Reynolds, Sheila M., Zhao, Yanyan, Climente-Gonzalez, Hector, Chai, Shengjie, Wang, Fang, Varghese, Rajees, Huang, Mo, Liang, Wen-Wei, Wyczalkowski, Matthew A., Sengupta, Sohini, Li, Zhi, Payne, Samuel H., Fenyo, David, Miner, Jeffrey H., Walter, Matthew J., Vincent, Benjamin, Eyras, Eduardo, Chen, Ken, Shmulevich, Ilya, Chen, Feng, Ding, Li, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Systematic Analysis of Splice-Site-Creating Mutations in Cancer. Cell Reports, 23 (1), 270-281.e3. doi: 10.1016/j.celrep.2018.03.052

Systematic Analysis of Splice-Site-Creating Mutations in Cancer

2018

Journal Article

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

Campbell, Joshua D., Yau, Christina, Bowlby, Reanne, Liu, Yuexin, Brennan, Kevin, Fan, Huihui, Taylor, Alison M., Wang, Chen, Walter, Vonn, Akbani, Rehan, Byers, Lauren Averett, Creighton, Chad J., Coarfa, Cristian, Shih, Juliann, Cherniack, Andrew D., Gevaert, Olivier, Prunello, Marcos, Shen, Hui, Anur, Pavana, Chen, Jianhong, Cheng, Hui, Hayes, D. Neil, Bullman, Susan, Pedamallu, Chandra Sekhar, Ojesina, Akinyemi I., Sadeghi, Sara, Mungall, Karen L., Robertson, A. Gordon, Benz, Christopher ... Yang, Ian (2018). Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas. Cell Reports, 23 (1), 194-212.e6. doi: 10.1016/j.celrep.2018.03.063

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

2018

Journal Article

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

Ricketts, Christopher J., de Cubas, Aguirre A., Fan, Huihui, Smith, Christof C., Lang, Martin, Reznik, Ed, Bowlby, Reanne, Gibb, Ewan A., Akbani, Rehan, Beroukhim, Rameen, Bottaro, Donald P., Choueiri, Toni K., Gibbs, Richard A., Godwin, Andrew K., Haake, Scott, Hakimi, A. Ari, Henske, Elizabeth P., Hsieh, James J., Ho, Thai H., Kanchi, Rupa S., Krishnan, Bhavani, Kwaitkowski, David J., Lui, Wembin, Merino, Maria J., Mills, Gordon B., Myers, Jerome, Nickerson, Michael L., Reuter, Victor E., Schmidt, Laura S. ... Yang, Ian (2018). The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma. Cell Reports, 23 (1), 313-326.e5. doi: 10.1016/j.celrep.2018.03.075

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

2018

Journal Article

Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

Ellrott, Kyle, Bailey, Matthew H., Saksena, Gordon, Covington, Kyle R., Kandoth, Cyriac, Stewart, Chip, Hess, Julian, Ma, Singer, Chiotti, Kami E., McLellan, Michael, Sofia, Heidi J., Hutter, Carolyn, Getz, Gad, Wheeler, David, Ding, Li, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines. Cell Systems, 6 (3), 271-281.e7. doi: 10.1016/j.cels.2018.03.002

Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

2018

Journal Article

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

Schaub, Franz X., Dhankani, Varsha, Berger, Ashton C., Trivedi, Mihir, Richardson, Anne B., Shaw, Reid, Zhao, Wei, Zhang, Xiaoyang, Ventura, Andrea, Liu, Yuexin, Ayer, Donald E., Hurlin, Peter J., Cherniack, Andrew D., Eisenman, Robert N., Bernard, Brady, Grandori, Carla, The Cancer Genome Atlas Network and Yang, Ian (2018). Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas. Cell Systems, 6 (3), 282-300.e2. doi: 10.1016/j.cels.2018.03.003

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

2018

Journal Article

Editorial on PanCan study

Marshall, Henry M., Yang, Ian A., Bowman, Rayleen V. and Fong, Kwun M. (2018). Editorial on PanCan study. Translational Lung Cancer Research, 7 (Suppl 1), S57-S59. doi: 10.21037/tlcr.2018.01.17

Editorial on PanCan study

2018

Journal Article

The contribution of respiratory microbiome analysis to a treatable traits model of care

Taylor, Steven L., O'Farrell, Hannah E., Simpson, Jodie L., Yang, Ian A. and Rogers, Geraint B. (2018). The contribution of respiratory microbiome analysis to a treatable traits model of care. Respirology, 24 (1), 19-28. doi: 10.1111/resp.13411

The contribution of respiratory microbiome analysis to a treatable traits model of care

2017

Journal Article

COPD-X australian and New Zealand guidelines for the diagnosis and management of chronic obstructive pulmonary disease: 2017 update

Yang, Ian A., Brown, Juliet L., George, Johnson, Jenkins, Sue, McDonald, Christine F., McDonald, Vanessa M., Phillips, Kirsten, Smith, Brian J., Zwar, Nicholas A. and Dabscheck, Eli (2017). COPD-X australian and New Zealand guidelines for the diagnosis and management of chronic obstructive pulmonary disease: 2017 update. Medical Journal of Australia, 207 (10), 436-442. doi: 10.5694/mja17.00686

COPD-X australian and New Zealand guidelines for the diagnosis and management of chronic obstructive pulmonary disease: 2017 update

2017

Journal Article

The effect of different radiological models on diagnostic accuracy and lung cancer screening performance

Marshall, Henry M., Zhao, Henry, Bowman, Rayleen V., Passmore, Linda H., McCaul, Elizabeth M., Yang, Ian A. and Fong, Kwun M. (2017). The effect of different radiological models on diagnostic accuracy and lung cancer screening performance. Thorax, 72 (12), 1147-1150. doi: 10.1136/thoraxjnl-2016-209624

The effect of different radiological models on diagnostic accuracy and lung cancer screening performance

2017

Journal Article

Ultrafine particle transport and deposition in a large scale 17-generation lung model

Islam, Mohammad S., Saha, Suvash C., Sauret, Emilie, Gemci, Tevfik, Yang, Ian A. and Gu, Y. T. (2017). Ultrafine particle transport and deposition in a large scale 17-generation lung model. Journal of Biomechanics, 64, 16-25. doi: 10.1016/j.jbiomech.2017.08.028

Ultrafine particle transport and deposition in a large scale 17-generation lung model

2017

Journal Article

Is Digital Tomosynthesis on Par With Computed Tomography for the Detection and Measurement of Pulmonary Nodules?

Lee, Xiang Wen, Marshall, Henry M., Leong, Steven C., O'Rourke, Rachael L., Steinke, Karin, Mirjalili, Negar, Bowman, Rayleen V., Yang, Ian A. and Fong, Kwun M. (2017). Is Digital Tomosynthesis on Par With Computed Tomography for the Detection and Measurement of Pulmonary Nodules?. Journal of Thoracic Imaging, 32 (6), W67-W68. doi: 10.1097/RTI.0000000000000298

Is Digital Tomosynthesis on Par With Computed Tomography for the Detection and Measurement of Pulmonary Nodules?

2017

Journal Article

RE: Proportion of Never-Smoker Non-Small Cell Lung Cancer Patients at Three Diverse Institutions

Page, Barbara J, Bowman, Rayleen V, Yang, Ian A and Fong, Kwun M (2017). RE: Proportion of Never-Smoker Non-Small Cell Lung Cancer Patients at Three Diverse Institutions. Journal of the National Cancer Institute, 110 (4), 432-432. doi: 10.1093/jnci/djx216

RE: Proportion of Never-Smoker Non-Small Cell Lung Cancer Patients at Three Diverse Institutions

2017

Journal Article

Ist eine thrombophilie-untersuchung bei patienten mit venöser thromboembolie notwendig?

Kudo, M., Lee, H. L., Yang, I. A. and Masel, P. J. (2017). Ist eine thrombophilie-untersuchung bei patienten mit venöser thromboembolie notwendig?. Vasomed, 29 (5).

Ist eine thrombophilie-untersuchung bei patienten mit venöser thromboembolie notwendig?