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2018

Journal Article

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

Gao, Qingsong, Liang, Wen-Wei, Foltz, Steven M., Mutharasu, Gnanavel, Jayasinghe, Reyka G., Cao, Song, Liao, Wen-Wei, Reynolds, Sheila M., Wyczalkowski, Matthew A., Yao, Lijun, Yu, Lihua, Sun, Sam Q., Chen, Ken, Lazar, Alexander J., Fields, Ryan C., Wendl, Michael C., Van Tine, Brian A., Vij, Ravi, Chen, Feng, Nykter, Matti, Shmulevich, Ilya, Ding, Li, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Driver Fusions and Their Implications in the Development and Treatment of Human Cancers. Cell Reports, 23 (1), 227-238.e3. doi: 10.1016/j.celrep.2018.03.050

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

2018

Journal Article

Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers

Peng, Xinxin, Chen, Zhongyuan, Farshidfar, Farshad, Xu, Xiaoyan, Lorenzi, Philip L., Wang, Yumeng, Cheng, Feixiong, Tan, Lin, Mojumdar, Kamalika, Du, Di, Ge, Zhongqi, Li, Jun, Thomas, George V., Birsoy, Kivanc, Liu, Lingxiang, Zhang, Huiwen, Zhao, Zhongming, Marchand, Calena, Weinstein, John N., Bathe, Oliver F., Liang, Han, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers. Cell Reports, 23 (1), 255-269.e4. doi: 10.1016/j.celrep.2018.03.077

Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers

2018

Journal Article

Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

Saltz, Joel, Gupta, Rajarsi, Hou, Le, Kurc, Tahsin, Singh, Pankaj, Nguyen, Vu, Samaras, Dimitris, Shroyer, Kenneth R., Zhao, Tianhao, Batiste, Rebecca, Van Arnam, John, Shmulevich, Ilya, Rao, Arvind U. K., Lazar, Alexander J., Sharma, Ashish, Thorsson, Vesteinn, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images. Cell Reports, 23 (1), 181-193.e7. doi: 10.1016/j.celrep.2018.03.086

Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

2018

Journal Article

Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

Knijnenburg, Theo A., Wang, Linghua, Zimmermann, Michael T., Chambwe, Nyasha, Gao, Galen F., Cherniack, Andrew D., Fan, Huihui, Shen, Hui, Way, Gregory P., Greene, Casey S., Liu, Yuexin, Akbani, Rehan, Feng, Bin, Donehower, Lawrence A., Miller, Chase, Shen, Yang, Karimi, Mostafa, Chen, Haoran, Kim, Pora, Jia, Peilin, Shinbrot, Eve, Zhang, Shaojun, Liu, Jianfang, Hu, Hai, Bailey, Matthew H., Yau, Christina, Wolf, Denise, Zhao, Zhongming, Weinstein, John N. ... Yang, Ian (2018). Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas. Cell Reports, 23 (1), 239-254.e6. doi: 10.1016/j.celrep.2018.03.076

Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

2018

Journal Article

Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

Ge, Zhongqi, Leighton, Jake S., Wang, Yumeng, Peng, Xinxin, Chen, Zhongyuan, Chen, Hu, Sun, Yutong, Yao, Fan, Li, Jun, Zhang, Huiwen, Liu, Jianfang, Shriver, Craig D., Hu, Hai, Piwnica-Worms, Helen, Ma, Li, Liang, Han, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types. Cell Reports, 23 (1), 213-226.e3. doi: 10.1016/j.celrep.2018.03.047

Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

2018

Journal Article

Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas

Way, Gregory P., Sanchez-Vega, Francisco, La, Konnor, Armenia, Joshua, Chatila, Walid K., Luna, Augustin, Sander, Chris, Cherniack, Andrew D., Mina, Marco, Ciriello, Giovanni, Schultz, Nikolaus, Sanchez, Yolanda, Greene, Casey S., The Cancer Genome Atlas Research Network and Yang, Ian (2018). Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas. Cell Reports, 23 (1), 172-180.e3. doi: 10.1016/j.celrep.2018.03.046

Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas

2018

Journal Article

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

Chiu, Hua-Sheng, Somvanshi, Sonal, Patel, Ektaben, Chen, Ting-Wen, Singh, Vivek P., Zorman, Barry, Patil, Sagar L., Pan, Yinghong, Chatterjee, Sujash S., Sood, Anil K., Gunaratne, Preethi H., Sumazin, Pavel, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context. Cell Reports, 23 (1), 297-312.e12. doi: 10.1016/j.celrep.2018.03.064

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

2018

Journal Article

Systematic Analysis of Splice-Site-Creating Mutations in Cancer

Jayasinghe, Reyka G., Cao, Song, Gao, Qingsong, Wendl, Michael C., Vo, Nam Sy, Reynolds, Sheila M., Zhao, Yanyan, Climente-Gonzalez, Hector, Chai, Shengjie, Wang, Fang, Varghese, Rajees, Huang, Mo, Liang, Wen-Wei, Wyczalkowski, Matthew A., Sengupta, Sohini, Li, Zhi, Payne, Samuel H., Fenyo, David, Miner, Jeffrey H., Walter, Matthew J., Vincent, Benjamin, Eyras, Eduardo, Chen, Ken, Shmulevich, Ilya, Chen, Feng, Ding, Li, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Systematic Analysis of Splice-Site-Creating Mutations in Cancer. Cell Reports, 23 (1), 270-281.e3. doi: 10.1016/j.celrep.2018.03.052

Systematic Analysis of Splice-Site-Creating Mutations in Cancer

2018

Journal Article

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

Campbell, Joshua D., Yau, Christina, Bowlby, Reanne, Liu, Yuexin, Brennan, Kevin, Fan, Huihui, Taylor, Alison M., Wang, Chen, Walter, Vonn, Akbani, Rehan, Byers, Lauren Averett, Creighton, Chad J., Coarfa, Cristian, Shih, Juliann, Cherniack, Andrew D., Gevaert, Olivier, Prunello, Marcos, Shen, Hui, Anur, Pavana, Chen, Jianhong, Cheng, Hui, Hayes, D. Neil, Bullman, Susan, Pedamallu, Chandra Sekhar, Ojesina, Akinyemi I., Sadeghi, Sara, Mungall, Karen L., Robertson, A. Gordon, Benz, Christopher ... Yang, Ian (2018). Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas. Cell Reports, 23 (1), 194-212.e6. doi: 10.1016/j.celrep.2018.03.063

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

2018

Journal Article

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

Ricketts, Christopher J., de Cubas, Aguirre A., Fan, Huihui, Smith, Christof C., Lang, Martin, Reznik, Ed, Bowlby, Reanne, Gibb, Ewan A., Akbani, Rehan, Beroukhim, Rameen, Bottaro, Donald P., Choueiri, Toni K., Gibbs, Richard A., Godwin, Andrew K., Haake, Scott, Hakimi, A. Ari, Henske, Elizabeth P., Hsieh, James J., Ho, Thai H., Kanchi, Rupa S., Krishnan, Bhavani, Kwaitkowski, David J., Lui, Wembin, Merino, Maria J., Mills, Gordon B., Myers, Jerome, Nickerson, Michael L., Reuter, Victor E., Schmidt, Laura S. ... Yang, Ian (2018). The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma. Cell Reports, 23 (1), 313-326.e5. doi: 10.1016/j.celrep.2018.03.075

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

2018

Journal Article

Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

Ellrott, Kyle, Bailey, Matthew H., Saksena, Gordon, Covington, Kyle R., Kandoth, Cyriac, Stewart, Chip, Hess, Julian, Ma, Singer, Chiotti, Kami E., McLellan, Michael, Sofia, Heidi J., Hutter, Carolyn, Getz, Gad, Wheeler, David, Ding, Li, The Cancer Genome Atlas Research Network and Yang, Ian (2018). Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines. Cell Systems, 6 (3), 271-281.e7. doi: 10.1016/j.cels.2018.03.002

Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

2018

Journal Article

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

Schaub, Franz X., Dhankani, Varsha, Berger, Ashton C., Trivedi, Mihir, Richardson, Anne B., Shaw, Reid, Zhao, Wei, Zhang, Xiaoyang, Ventura, Andrea, Liu, Yuexin, Ayer, Donald E., Hurlin, Peter J., Cherniack, Andrew D., Eisenman, Robert N., Bernard, Brady, Grandori, Carla, The Cancer Genome Atlas Network and Yang, Ian (2018). Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas. Cell Systems, 6 (3), 282-300.e2. doi: 10.1016/j.cels.2018.03.003

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

2018

Journal Article

Editorial on PanCan study

Marshall, Henry M., Yang, Ian A., Bowman, Rayleen V. and Fong, Kwun M. (2018). Editorial on PanCan study. Translational Lung Cancer Research, 7 (Suppl 1), S57-S59. doi: 10.21037/tlcr.2018.01.17

Editorial on PanCan study

2018

Conference Publication

Management of acute COPD exacerbations: Do we follow the guidelines?

Cousins, J., Wood-Baker, R., Wark, P., Yang, I., Hutchinson, A., Sajkov, D., Gibson, P. and Mcdonald, V. (2018). Management of acute COPD exacerbations: Do we follow the guidelines?. The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting, Adelaide, Australia, 23–27 March 2018. Hoboken, NJ United States: Wiley.

Management of acute COPD exacerbations: Do we follow the guidelines?

2018

Journal Article

The contribution of respiratory microbiome analysis to a treatable traits model of care

Taylor, Steven L., O'Farrell, Hannah E., Simpson, Jodie L., Yang, Ian A. and Rogers, Geraint B. (2018). The contribution of respiratory microbiome analysis to a treatable traits model of care. Respirology, 24 (1), 19-28. doi: 10.1111/resp.13411

The contribution of respiratory microbiome analysis to a treatable traits model of care

2018

Conference Publication

Primary human bronchial epithelial cell responses to diesel and novel biodiesel emissions

Vaughan, Annalicia, Stevanovic, Svetlana, Jafari, Mohammad, Bowman, Rayleen, Fong, Kwun, Ristovski, Zoran and Yang, Ian (2018). Primary human bronchial epithelial cell responses to diesel and novel biodiesel emissions. 28th International Congress of the European Respiratory Society (ERS), Paris, France, 15-19 September 2018. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2018.PA4243

Primary human bronchial epithelial cell responses to diesel and novel biodiesel emissions

2018

Conference Publication

Association between bacterial load and inflammatory gene expression in COPD exacerbations

O'Farrell, Hannah, Shaw, Janet, Bowman, Rayleen, Fong, Kwun and Yang, Ian (2018). Association between bacterial load and inflammatory gene expression in COPD exacerbations. 28th International Congress of the European-Respiratory-Society (ERS), Paris, France, 15-19 September 2018. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2018.PA3864

Association between bacterial load and inflammatory gene expression in COPD exacerbations

2018

Conference Publication

Sputum biospecimen quality and suitability for microbiome characterisation in COPD

Shaw, Janet, O'Farrell, Hannah, Ferry, Olivia, Fung, Pamela, Courtney, Deborah, Bowman, Rayleen, Fong, Kwun and Yang, Ian (2018). Sputum biospecimen quality and suitability for microbiome characterisation in COPD. 28th International Congress of the European-Respiratory-Society (ERS), Paris, France, 15-19 September 2018. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2018.PA5304

Sputum biospecimen quality and suitability for microbiome characterisation in COPD

2017

Journal Article

COPD-X australian and New Zealand guidelines for the diagnosis and management of chronic obstructive pulmonary disease: 2017 update

Yang, Ian A., Brown, Juliet L., George, Johnson, Jenkins, Sue, McDonald, Christine F., McDonald, Vanessa M., Phillips, Kirsten, Smith, Brian J., Zwar, Nicholas A. and Dabscheck, Eli (2017). COPD-X australian and New Zealand guidelines for the diagnosis and management of chronic obstructive pulmonary disease: 2017 update. Medical Journal of Australia, 207 (10), 436-442. doi: 10.5694/mja17.00686

COPD-X australian and New Zealand guidelines for the diagnosis and management of chronic obstructive pulmonary disease: 2017 update

2017

Journal Article

The effect of different radiological models on diagnostic accuracy and lung cancer screening performance

Marshall, Henry M., Zhao, Henry, Bowman, Rayleen V., Passmore, Linda H., McCaul, Elizabeth M., Yang, Ian A. and Fong, Kwun M. (2017). The effect of different radiological models on diagnostic accuracy and lung cancer screening performance. Thorax, 72 (12), 1147-1150. doi: 10.1136/thoraxjnl-2016-209624

The effect of different radiological models on diagnostic accuracy and lung cancer screening performance