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2024

Journal Article

The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis

Murray, Jayne E., Valli, Emanuele, Milazzo, Giorgio, Mayoh, Chelsea, Gifford, Andrew J., Fletcher, Jamie I., Xue, Chengyuan, Jayatilleke, Nisitha, Salehzadeh, Firoozeh, Gamble, Laura D., Rouaen, Jourdin R. C., Carter, Daniel R., Forgham, Helen, Sekyere, Eric O., Keating, Joanna, Eden, Georgina, Allan, Sophie, Alfred, Stephanie, Kusuma, Frances K., Clark, Ashleigh, Webber, Hannah, Russell, Amanda J., de Weck, Antoine, Kile, Benjamin T., Santulli, Martina, De Rosa, Piergiuseppe, Fleuren, Emmy D. G., Gao, Weiman, Wilkinson-White, Lorna ... Norris, Murray D. (2024). The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis. Nature Communications, 15 (1) 5585, 5585. doi: 10.1038/s41467-024-49871-0

The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis

2024

Journal Article

Multifunctional fluoropolymer‐engineered magnetic nanoparticles to facilitate blood‐brain barrier penetration and effective gene silencing in medulloblastoma

Forgham, Helen, Zhu, Jiayuan, Huang, Xumin, Zhang, Cheng, Biggs, Heather, Liu, Liwei, Wang, Yi Cheng, Fletcher, Nicholas, Humphries, James, Cowin, Gary, Mardon, Karine, Kavallaris, Maria, Thurecht, Kristofer, Davis, Thomas P. and Qiao, Ruirui (2024). Multifunctional fluoropolymer‐engineered magnetic nanoparticles to facilitate blood‐brain barrier penetration and effective gene silencing in medulloblastoma. Advanced Science, 11 (25) 2401340, e2401340. doi: 10.1002/advs.202401340

Multifunctional fluoropolymer‐engineered magnetic nanoparticles to facilitate blood‐brain barrier penetration and effective gene silencing in medulloblastoma

2024

Journal Article

Fluorine-modified polymers reduce the adsorption of immune-reactive proteins to PEGylated gold nanoparticles

Forgham, Helen, Zhu, Jiayuan, Zhang, Taoran, Huang, Xumin, Li, Xiangke, Shen, Ao, Biggs, Heather, Talbo, Gert, Xu, Chun, Davis, Thomas P. and Qiao, Ruirui (2024). Fluorine-modified polymers reduce the adsorption of immune-reactive proteins to PEGylated gold nanoparticles. Nanomedicine, 19 (11), 995-1012. doi: 10.2217/nnm-2023-0357

Fluorine-modified polymers reduce the adsorption of immune-reactive proteins to PEGylated gold nanoparticles

2024

Journal Article

Nanoengineering liquid metal core–shell nanostructures

Lu, Hongda, Tang, Shi‐Yang, Zhu, Jiayuan, Huang, Xumin, Forgham, Helen, Li, Xiangke, Shen, Ao, Yun, Guolin, Hu, Jinming, Zhang, Shiwu, Davis, Thomas P., Li, Weihua and Qiao, Ruirui (2024). Nanoengineering liquid metal core–shell nanostructures. Advanced Functional Materials, 34 (6) 2311300. doi: 10.1002/adfm.202311300

Nanoengineering liquid metal core–shell nanostructures

2024

Journal Article

Tailored fluorosurfactants through controlled/living radical polymerization for highly stable microfluidic droplet generation

Li, Xiangke, Tang, Shi‐Yang, Zhang, Yang, Zhu, Jiayuan, Forgham, Helen, Zhao, Chun‐Xia, Zhang, Cheng, Davis, Thomas P. and Qiao, Ruirui (2024). Tailored fluorosurfactants through controlled/living radical polymerization for highly stable microfluidic droplet generation. Angewandte Chemie, 136 (3) e202315552, 1-9. doi: 10.1002/ange.202315552

Tailored fluorosurfactants through controlled/living radical polymerization for highly stable microfluidic droplet generation

2023

Journal Article

Tailored fluorosurfactants through controlled/living radical polymerization for highly stable microfluidic droplet generation

Li, Xiangke, Tang, Shi-Yang, Zhang, Yang, Zhu, Jiayuan, Forgham, Helen, Zhao, Chun-Xia, Zhang, Cheng, Davis, Thomas P. and Qiao, Ruirui (2023). Tailored fluorosurfactants through controlled/living radical polymerization for highly stable microfluidic droplet generation. Angewandte Chemie International Edition, 63 (3) e202315552, e202315552. doi: 10.1002/anie.202315552

Tailored fluorosurfactants through controlled/living radical polymerization for highly stable microfluidic droplet generation

2023

Journal Article

Antifouling surface coatings for the next generation of nanomedicine: toward in vivo immune evasion

Forgham, Helen, Liu, Liwei, Davis, Thomas P and Qiao, Ruirui (2023). Antifouling surface coatings for the next generation of nanomedicine: toward in vivo immune evasion. Nanomedicine, 18 (27), 1997-2000. doi: 10.2217/nnm-2023-0316

Antifouling surface coatings for the next generation of nanomedicine: toward in vivo immune evasion

2023

Journal Article

Alzheimer's progenitor amyloid‐β targets and dissolves microbial amyloids and impairs biofilm function

Ali, Syed Aoun, Chung, Ka Hang Karen, Forgham, Helen, Olsen, William P., Kakinen, Aleksandr, Balaji, Arunpandian, Otzen, Daniel E., Davis, Thomas Paul and Javed, Ibrahim (2023). Alzheimer's progenitor amyloid‐β targets and dissolves microbial amyloids and impairs biofilm function. Advanced Science, 10 (29) 2301423, e2301423. doi: 10.1002/advs.202301423

Alzheimer's progenitor amyloid‐β targets and dissolves microbial amyloids and impairs biofilm function

2023

Journal Article

Vector enabled CRISPR gene editing – A revolutionary strategy for targeting the diversity of brain pathologies

Forgham, Helen, Liu, Liwei, Zhu, Jiayuan, Javed, Ibrahim, Cai, Weibo, Qiao, Ruirui and Davis, Thomas P. (2023). Vector enabled CRISPR gene editing – A revolutionary strategy for targeting the diversity of brain pathologies. Coordination Chemistry Reviews, 487 215172. doi: 10.1016/j.ccr.2023.215172

Vector enabled CRISPR gene editing – A revolutionary strategy for targeting the diversity of brain pathologies

2023

Journal Article

Magnetic iron oxide nanoparticles for brain imaging and drug delivery

Qiao, Ruirui, Fu, Changkui, Forgham, Helen, Javed, Ibrahim, Huang, Xumin, Zhu, Jiayuan, Whittaker, Andrew K. and Davis, Thomas P. (2023). Magnetic iron oxide nanoparticles for brain imaging and drug delivery. Advanced Drug Delivery Reviews, 197 114822, 1-31. doi: 10.1016/j.addr.2023.114822

Magnetic iron oxide nanoparticles for brain imaging and drug delivery

2023

Journal Article

Dual-ratiometric magnetic resonance tunable nanoprobe with acidic-microenvironment-responsive property to enhance the visualization of early tumor pathological changes

Cao, Rong, Tang, Ning, Zhu, Yi, Chen, An, Li, Yumeng, Ge, Renbin, Li, Yuan, Huang, Zhongyi, Guo, Jiajing, Deng, Jiali, Lu, Hongwei, Lu, Ziwei, Forgham, Helen, Davis, Thomas P., Qiao, Ruirui and Wang, Zhongling (2023). Dual-ratiometric magnetic resonance tunable nanoprobe with acidic-microenvironment-responsive property to enhance the visualization of early tumor pathological changes. Nano Research, 16 (7), 10034-10046. doi: 10.1007/s12274-023-5679-x

Dual-ratiometric magnetic resonance tunable nanoprobe with acidic-microenvironment-responsive property to enhance the visualization of early tumor pathological changes

2022

Journal Article

Star polymer nanomedicines─challenges and future perspectives

Forgham, Helen, Zhu, Jiayuan, Qiao, Ruirui and Davis, Thomas P. (2022). Star polymer nanomedicines─challenges and future perspectives. ACS Applied Polymer Materials, 4 (10), 6784-6796. doi: 10.1021/acsapm.2c01291

Star polymer nanomedicines─challenges and future perspectives

2022

Journal Article

Nanomaterials integrated 3D printing for biomedical application

Zhang, Liwen, Forgham, Helen, Shen, Ao, Wang, Jiafan, Zhu, Jiayuan, Huang, Xumin, Tang, Shiyang, Xu, Chun, Davis, Thomas P. and Qiao, Ruirui (2022). Nanomaterials integrated 3D printing for biomedical application. Journal of Materials Chemistry B, 10 (37), 7473-7490. doi: 10.1039/d2tb00931e

Nanomaterials integrated 3D printing for biomedical application

2022

Journal Article

Keeping up with the COVID's—Could siRNA‐based antivirals be a part of the answer?

Forgham, Helen, Kakinen, Aleksandr, Qiao, Ruirui and Davis, Thomas P. (2022). Keeping up with the COVID's—Could siRNA‐based antivirals be a part of the answer?. Exploration, 00 (6) 20220012, 20220012. doi: 10.1002/exp.20220012

Keeping up with the COVID's—Could siRNA‐based antivirals be a part of the answer?

2022

Journal Article

Aerosol delivery of star polymer-siRNA nanoparticles as a therapeutic strategy to inhibit lung tumor growth

Ma, Z., Wong, S.W., Forgham, H., Esser, L., Lai, M., Leiske, M.N., Kempe, K., Sharbeen, G., Youkhana, J., Mansfeld, F., Quinn, J.F., Phillips, P.A., Davis, T.P., Kavallaris, M. and McCarroll, J.A. (2022). Aerosol delivery of star polymer-siRNA nanoparticles as a therapeutic strategy to inhibit lung tumor growth. Biomaterials, 285 121539, 121539. doi: 10.1016/j.biomaterials.2022.121539

Aerosol delivery of star polymer-siRNA nanoparticles as a therapeutic strategy to inhibit lung tumor growth

2022

Journal Article

All-in-one inorganic nanoagents for near-infrared-II photothermal-based cancer theranostics

Zhang, L., Forgham, H., Huang, X., Shen, A., Davis, T.P., Qiao, R. and Guo, B. (2022). All-in-one inorganic nanoagents for near-infrared-II photothermal-based cancer theranostics. Materials Today Advances, 14 100226, 100226. doi: 10.1016/j.mtadv.2022.100226

All-in-one inorganic nanoagents for near-infrared-II photothermal-based cancer theranostics

2022

Journal Article

Recent advances in single Fe-based nanoagents for photothermal–chemodynamic cancer therapy

Zhang, Li, Forgham, Helen, Shen, Ao, Qiao, Ruirui and Guo, Bing (2022). Recent advances in single Fe-based nanoagents for photothermal–chemodynamic cancer therapy. Biosensors, 12 (2) 86, 86. doi: 10.3390/bios12020086

Recent advances in single Fe-based nanoagents for photothermal–chemodynamic cancer therapy

2021

Journal Article

Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma

Janjua, Taskeen Iqbal, Ahmed-Cox, Aria, Meka, Anand Kumar, Mansfeld, Friederike M., Forgham, Helen, Ignacio, Rosa Mistica C., Cao, Yuxue, McCarroll, Joshua A., Mazzieri, Roberta, Kavallaris, Maria and Popat, Amirali (2021). Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma. Nanoscale, 13 (40), 16909-16922. doi: 10.1039/d1nr03553c

Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma

2020

Conference Publication

Development and Biological Optimization of Star-Shaped Polymeric Nanoparticles for the Delivery of Therapeutic siRNA to Lung Cancer Cells In Vitro and In Vivo

Ma, Zerong, Esser, Lars, Lai, May, Leiske, Meike N., Forgham, Helen, Wong, Sze W., Mansfeld, Friederike M., Lewis, Craig R., Davis, Thomas P., Quinn, John, Phillips, Phoebe, Kavallaris, Maria and McCarroll, Joshua A. (2020). Development and Biological Optimization of Star-Shaped Polymeric Nanoparticles for the Delivery of Therapeutic siRNA to Lung Cancer Cells In Vitro and In Vivo. 23rd Annual Meeting of the American-Society-for-Gene-and-Cell-Therapy, Electr Network, 12-15 May 2020. Cambridge, MA, United States: Cell Press.

Development and Biological Optimization of Star-Shaped Polymeric Nanoparticles for the Delivery of Therapeutic siRNA to Lung Cancer Cells In Vitro and In Vivo

2019

Journal Article

Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia

Somers, Klaartje, Evans, Kathryn, Cheung, Leanna, Karsa, Mawar, Pritchard, Tara, Kosciolek, Angelika, Bongers, Angelika, El-Ayoubi, Ali, Forgham, Helen, Middlemiss, Shiloh, Mayoh, Chelsea, Jones, Luke, Gupta, Mahima, Kees, Ursula R., Chernova, Olga, Korotchkina, Lioubov, Gudkov, Andrei V., Erickson, Stephen W., Teicher, Beverly, Smith, Malcolm A., Norris, Murray D., Haber, Michelle, Lock, Richard B. and Henderson, Michelle J. (2019). Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia. Leukemia, 34 (6), 1524-1539. doi: 10.1038/s41375-019-0683-6

Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia