|
2017 Journal Article FBXO31 protects against genomic instability by capping FOXM1 levels at the G2/M transitionJeffery, J. M., Kalimutho, M., Johansson, P., Cardenas, D. G., Kumar, R. and Khanna, K. K. (2017). FBXO31 protects against genomic instability by capping FOXM1 levels at the G2/M transition. Oncogene, 36 (7), 1012-1022. doi: 10.1038/onc.2016.268 |
|
2017 Journal Article The metastasis suppressor RARRES3 as an endogenous inhibitor of the immunoproteasome expression in breast cancer cellsAnderson, Alison M., Kalimutho, Murugan, Harten, Sarah, Nanayakkara, Devathri M., Khanna, Kum Kum and Ragan, Mark A. (2017). The metastasis suppressor RARRES3 as an endogenous inhibitor of the immunoproteasome expression in breast cancer cells. Scientific Reports, 7 (1) 39873. doi: 10.1038/srep39873 |
|
2016 Journal Article RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesisBond, Catherine E., McKeone, Diane M., Kalimutho, Murugan, Bettington, Mark L., Pearson, Sally-Ann, Dumenil, Troy D., Wockner, Leesa F., Burge, Matthew, Leggett, Barbara A. and Whitehall, Vicki L. J. (2016). RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis. Oncotarget, 7 (43), 70589-70600. doi: 10.18632/oncotarget.12130 |
|
2016 Journal Article Adenosine 2B receptor expression on cancer cells promotes metastasisMittal, Deepak, Sinha, Debottam, Barkauskas, Deborah, Young, Arabella, Kalimutho, Murugan, Stannard, Kimberley, Caramia, Franco, Haibe-Kains, Benjamin, Stagg, John, Khanna, Kum Kum, Loi, Sherene and Smyth, Mark J. (2016). Adenosine 2B receptor expression on cancer cells promotes metastasis. Cancer Research, 76 (15), 4372-4382. doi: 10.1158/0008-5472.CAN-16-0544 |
|
2016 Journal Article Understanding the functional impact of copy number alterations in breast cancer using a network modeling approachSrihari, Sriganesh, Kalimutho, Murugan, Lal, Samir, Singla, Jitin, Patel, Dhaval, Simpson, Peter T., Khanna, Kum Kum and Ragan, Mark A. (2016). Understanding the functional impact of copy number alterations in breast cancer using a network modeling approach. Molecular Biosystems, 12 (3), 963-972. doi: 10.1039/C5MB00655D |
|
2016 Journal Article Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancerFrench, Juliet D., Johnatty, Sharon E., Lu, Yi, Beesley, Jonathan, Gao, Bo, Kalimutho, Murugan, Henderson, Michelle J., Russell, Amanda J., Kar, Siddhartha, Chen, Xiaoging, Hillman, Kristine M., Kaufmann, S, Sivakumaran H., O'Reilly, Martin, Wang, Chen, Korbie, Darren J., Lambrechts, Diether, Despierre, Evelyn, Van Nieuwenhuysen, Els, Lambrechts, Sandra, Vergote, Ignace, Karlan, Beth, Lester, Jenny, Orsulic, Sandra, Walsh, Christine, Fasching, Peter A., Beckmann, Matthias W., Ekici, Arif B., Hein, Alexander ... MacGregor, Stuart (2016). Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer. Oncotarget, 7 (6), 6353-6368. doi: 10.18632/oncotarget.7047 |
|
2015 Journal Article Targeted Therapies for Triple-Negative Breast Cancer: Combating a Stubborn DiseaseKalimutho, Murugan, Parsons, Kate, Mittal, Deepak, Lopez, J.Alejandro, Srihari, Sriganesh and Khanna, Kum Kum (2015). Targeted Therapies for Triple-Negative Breast Cancer: Combating a Stubborn Disease. Trends in Pharmacological Sciences, 36 (12), 822-846. doi: 10.1016/j.tips.2015.08.009 |
|
2015 Journal Article Beyond cytokinesis: the emerging roles of CEP55 in tumorigenesisJeffery, J., Sinha, D., Srihari, S., Kalimutho, M. and Khanna, K. K. (2015). Beyond cytokinesis: the emerging roles of CEP55 in tumorigenesis. Oncogene, 35 (6), 683-690. doi: 10.1038/onc.2015.128 |
|
2014 Journal Article Natural killer cells are essential for the ability of BRAF inhibitors to control BRAFV600E-mutant metastatic melanomade Andrade, Lucas Ferrari, Ngiow, Shin F., Stannard, Kimberly, Rusakiewicz, Sylvie, Kalimutho, Murugan, Khanna, Kum Kum, Tey, Siok-Keen, Takeda, Kazyuoshi, Zitvogel, Laurence, Martinet, Ludovic and Smyth, Mark J. (2014). Natural killer cells are essential for the ability of BRAF inhibitors to control BRAFV600E-mutant metastatic melanoma. Cancer Research, 74 (24), 7298-7308. doi: 10.1158/0008-5472.CAN-14-1339 |
|
2014 Journal Article ADAM17-Dependent c-MET-STAT3 Signaling Mediates Resistance to MEK Inhibitors in KRAS Mutant Colorectal CancerVan Schaeybroeck, Sandra, Kalimutho, Murugan, Dunne, Philip D., Carson, Robbie, Allen, Wendy, Jithesh, Puthen V., Redmond, Keara L., Sasazuki, Takehiko, Shirasawa, Senji, Blayney, Jaine, Michieli, Paolo, Fenning, Cathy, Lenz, Heinz-Josef, Lawler, Mark, Longley, Daniel B. and Johnston, Patrick G. (2014). ADAM17-Dependent c-MET-STAT3 Signaling Mediates Resistance to MEK Inhibitors in KRAS Mutant Colorectal Cancer. Cell Reports, 7 (6), 1940-1955. doi: 10.1016/j.celrep.2014.05.032 |
|
2014 Journal Article Gemcitabine and CHK1 inhibition potentiate EGFR-directed radioimmunotherapy against pancreatic ductal adenocarcinomaAl-Ejeh, Fares, Pajic, Marina, Shi, Wei, Kalimutho, Murugan, Miranda, Mariska, Nagrial, Adnan M., Chou, Angela, Biankin, Andrew V., Grimmond, Sean M., Brown, Michael P. and Khanna, Kum Kum (2014). Gemcitabine and CHK1 inhibition potentiate EGFR-directed radioimmunotherapy against pancreatic ductal adenocarcinoma. Clinical Cancer Research, 20 (12), 3187-3197. doi: 10.1158/1078-0432.CCR-14-0048 |
|
2014 Journal Article Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancerAl-Ejeh, F., Simpson, P. T., Sanus, J. M., Klein, K., Kalimutho, M., Shi, W., Miranda, M., Kutasovic, J., Raghavendra, A., Madore, J., Reid, L., Krause, L., Chenevix-Trench, G., Lakhani, S. R. and Khanna, K. K. (2014). Meta-analysis of the global gene expression profile of triple-negative breast cancer identifies genes for the prognostication and treatment of aggressive breast cancer. Oncogenesis, 3 (4) e100, 1-12. doi: 10.1038/oncsis.2014.14 |
|
2014 Journal Article AXL is a key regulator of inherent and chemotherapy-induced invasion and predicts a poor clinical outcome in early-stage colon cancerDunne, Philip D., McArt, Darragh G., Blayney, Jaine K., Kalimutho, Murugan, Greer, Samanda, Wang, Tingting, Srivastava, Supriya, Ong, Chee Wee, Arthur, Ken, Loughrey, Maurice, Redmond, Keara, Longley, Daniel B., Salto-Tellez, Manuel, Johnston, Patrick G. and Van Schaeybroeck, Sandra (2014). AXL is a key regulator of inherent and chemotherapy-induced invasion and predicts a poor clinical outcome in early-stage colon cancer. Clinical Cancer Research, 20 (1), 164-175. doi: 10.1158/1078-0432.CCR-13-1354 |
|
2011 Journal Article Differential expression of miR-144* as a novel fecal-based diagnostic marker for colorectal cancerKalimutho, Murugan, Blanco, Giovanna Del Vecchio, Di Cecilia, Serena, Sileri, Pierpaolo, Cretella, Micaela, Pallone, Francesco, Federici, Giorgio and Bernardini, Sergio (2011). Differential expression of miR-144* as a novel fecal-based diagnostic marker for colorectal cancer. Journal of Gastroenterology, 46 (12), 1391-1402. doi: 10.1007/s00535-011-0456-0 |
|
2011 Journal Article Platinum-(IV)-derivative satraplatin induced G<sub>2</sub>/M cell cycle perturbation via p53-p21<sup>waf1/cip1</sup>-independent pathway in human colorectal cancer cellsKalimutho, Murugan, Minutolo, Antonella, Grelli, Sandro, Federici, Giorgio and Bernardini, Sergio (2011). Platinum-(IV)-derivative satraplatin induced G2/M cell cycle perturbation via p53-p21waf1/cip1-independent pathway in human colorectal cancer cells. Acta Pharmacologica Sinica, 32 (11), 1387-1396. doi: 10.1038/aps.2011.107 |
|
2011 Journal Article Salivary miRNAome profiling uncovers epithelial and proliferative miRNAs with differential expression across dentition stagesFormosa, Amanda, Piro, Maria Cristina, Docimo, Raffaella, Maturo, Paolo, Sollecito, Daniela Rita Maria, Kalimutho, Murugan, Sancesario, Giulia, Barlattani, Alberto, Melino, Gerry, Candi, Eleonora and Bernardini, Sergio (2011). Salivary miRNAome profiling uncovers epithelial and proliferative miRNAs with differential expression across dentition stages. Cell Cycle, 10 (19), 3359-3368. doi: 10.4161/cc.10.19.17647 |
|
2011 Journal Article Satraplatin (JM-216) mediates G2/M cell cycle arrest and potentiates apoptosis via multiple death pathways in colorectal cancer cells thus overcoming platinum chemo-resistanceKalimutho, Murugan, Minutolo, Antonella, Grelli, Sandro, Formosa, Amanda, Sancesario, Giulia, Valentini, Alessandra, Federici, Giorgio and Bernardini, Sergio (2011). Satraplatin (JM-216) mediates G2/M cell cycle arrest and potentiates apoptosis via multiple death pathways in colorectal cancer cells thus overcoming platinum chemo-resistance. Cancer Chemotherapy and Pharmacology, 67 (6), 1299-1312. doi: 10.1007/s00280-010-1428-4 |
|
2011 Journal Article Epigenetically silenced miR-34b/c as a novel faecal-based screening marker for colorectal cancerKalimutho, M., Di Cecilia, S., Blanco, G. Del Vecchio, Roviello, F., Sileri, P., Cretella, M., Formosa, A., Corso, G., Marrelli, D., Pallone, F., Federici, G. and Bernardini, S. (2011). Epigenetically silenced miR-34b/c as a novel faecal-based screening marker for colorectal cancer. British Journal of Cancer, 104 (11), 1770-1778. doi: 10.1038/bjc.2011.82 |
|
2011 Journal Article A simplified, non-invasive fecal-based DNA integrity assay and iFOBT for colorectal cancer detectionKalimutho, Murugan, Blanco, Giovanna Del Vecchio, Cretella, Micaela, Mannisi, Elena, Sileri, Pierpaolo, Formosa, Amanda, Pallone, Francesco, Federici, Giorgio and Bernardini, Sergio (2011). A simplified, non-invasive fecal-based DNA integrity assay and iFOBT for colorectal cancer detection. International Journal of Colorectal Disease, 26 (5), 583-592. doi: 10.1007/s00384-010-1128-x |
|
2010 Journal Article Quantitative denaturing high performance liquid chromatography (Q-dHPLC) detection of APC long DNA in faeces from patients with colorectal cancerKalimutho, Murugan, Blanco, Giovanna Del Vecchio, Gravina, Paolo, Cretella, Micaela, Mannucci, Liliana, Mannisi, Elena, Formosa, Amanda, Pallone, Francesco, Federici, Giorgio and Bernardini, Sergio (2010). Quantitative denaturing high performance liquid chromatography (Q-dHPLC) detection of APC long DNA in faeces from patients with colorectal cancer. Clinical Chemistry and Laboratory Medicine, 48 (9), 1303-1311. doi: 10.1515/CCLM.2010.245 |
