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2024

Journal Article

A novel inhibitor of class IIa histone deacetylases attenuates collagen‐induced arthritis

Poon, Eunice K., Liu, Ligong, Wu, Kai‐Chen, Lim, Junxian, Sweet, Matthew J., Lohman, Rink‐Jan, Iyer, Abishek and Fairlie, David P. (2024). A novel inhibitor of class IIa histone deacetylases attenuates collagen‐induced arthritis. British Journal of Pharmacology, 181 (23), 4804-4821. doi: 10.1111/bph.17306

A novel inhibitor of class IIa histone deacetylases attenuates collagen‐induced arthritis

2020

Journal Article

Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition

Kennedy, Amanda J., Sundström, Linda, Geschwindner, Stefan, Poon, Eunice K. Y., Jiang, Yuhong, Chen, Rongfeng, Cooke, Rob, Johnstone, Shawn, Madin, Andrew, Lim, Junxian, Liu, Qingqi, Lohman, Rink-Jan, Nordqvist, Anneli, Fridén-Saxin, Maria, Yang, Wenzhen, Brown, Dean G., Fairlie, David P. and Dekker, Niek (2020). Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition. Communications Biology, 3 (1) 782, 782. doi: 10.1038/s42003-020-01504-0

Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition

2020

Journal Article

Potent thiophene antagonists of human complement C3a receptor with anti-inflammatory activity

Rowley, Jessica A., Reid, Robert C., Poon, Eunice K. Y., Wu, Kai-Chen, Lim, Junxian, Lohman, Rink-Jan, Hamidon, Johan K., Yau, Mei-Kwan, Halili, Maria A., Durek, Thomas, Iyer, Abishek and Fairlie, David P. (2020). Potent thiophene antagonists of human complement C3a receptor with anti-inflammatory activity. Journal of Medicinal Chemistry, 63 (2) acs.jmedchem.9b00927, 529-541. doi: 10.1021/acs.jmedchem.9b00927

Potent thiophene antagonists of human complement C3a receptor with anti-inflammatory activity