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2022

Journal Article

A dimeric proteomimetic prevents SARS-CoV-2 infection by dimerizing the spike protein

Khatri, Bhavesh, Pramanick, Ishika, Malladi, Sameer Kumar, Rajmani, Raju S., Kumar, Sahil, Ghosh, Pritha, Sengupta, Nayanika, Rahisuddin, R., Kumar, Narender, Kumaran, S., Ringe, Rajesh P., Varadarajan, Raghavan, Dutta, Somnath and Chatterjee, Jayanta (2022). A dimeric proteomimetic prevents SARS-CoV-2 infection by dimerizing the spike protein. Nature Chemical Biology, 18 (10), 1046-1055. doi: 10.1038/s41589-022-01060-0

A dimeric proteomimetic prevents SARS-CoV-2 infection by dimerizing the spike protein

Featured

2021

Journal Article

Desolvation of Peptide Bond by O to S Substitution Impacts Protein Stability

Khatri, Bhavesh, Raghunathan, Shampa, Chakraborti, Sohini, Rahisuddin, R., Kumaran, S., Tadala, Raghu, Wagh, Padmakar, Priyakumar, U. Deva and Chatterjee, Jayanta (2021). Desolvation of Peptide Bond by O to S Substitution Impacts Protein Stability. Angewandte Chemie, 133 (47), 25074-25078. doi: 10.1002/ange.202110978

Desolvation of Peptide Bond by O to S Substitution Impacts Protein Stability

Featured

2021

Journal Article

Desolvation of peptide bond by O to S substitution impacts protein stability

Khatri, Bhavesh, Raghunathan, Shampa, Chakraborti, Sohini, Rahisuddin, R., Kumaran, S., Tadala, Raghu, Wagh, Padmakar, Priyakumar, U. Deva and Chatterjee, Jayanta (2021). Desolvation of peptide bond by O to S substitution impacts protein stability. Angewandte Chemie International Edition, 60 (47), 24870-24874. doi: 10.1002/anie.202110978

Desolvation of peptide bond by O to S substitution impacts protein stability

Featured

2020

Journal Article

Increasing protein stability by engineering the n → π* interaction at the β-turn

Khatri, Bhavesh, Majumder, Puja, Nagesh, Jayashree, Penmatsa, Aravind and Chatterjee, Jayanta (2020). Increasing protein stability by engineering the n → π* interaction at the β-turn. Chemical Science, 11 (35), 9480-9487. doi: 10.1039/d0sc03060k

Increasing protein stability by engineering the n → π* interaction at the β-turn

2023

Journal Article

An amide to thioamide substitution improves the permeability and bioavailability of macrocyclic peptides

Ghosh, Pritha, Raj, Nishant, Verma, Hitesh, Patel, Monika, Chakraborti, Sohini, Khatri, Bhavesh, Doreswamy, Chandrashekar M., Anandakumar, S. R., Seekallu, Srinivas, Dinesh, M. B., Jadhav, Gajanan, Yadav, Prem Narayan and Chatterjee, Jayanta (2023). An amide to thioamide substitution improves the permeability and bioavailability of macrocyclic peptides. Nature Communications, 14 (1) 6050. doi: 10.1038/s41467-023-41748-y

An amide to thioamide substitution improves the permeability and bioavailability of macrocyclic peptides

2022

Journal Article

Structural impact of thioamide incorporation into a β-hairpin

Fiore, Kristen E., Patist, Martijn J., Giannakoulias, Sam, Huang, Cheng-Hsin, Verma, Hitesh, Khatri, Bhavesh, Cheng, Richard P., Chatterjee, Jayanta and Petersson, E. James (2022). Structural impact of thioamide incorporation into a β-hairpin. RSC Chemical Biology, 3 (5), 582-591. doi: 10.1039/d1cb00229e

Structural impact of thioamide incorporation into a β-hairpin

2022

Journal Article

Graphene oxide as a dual template for induced helicity of peptides

Pandit, Subrata, Maroli, Nikhil, Naskar, Supriyo, Khatri, Bhavesh, Maiti, Prabal K. and De, Mrinmoy (2022). Graphene oxide as a dual template for induced helicity of peptides. Nanoscale, 14 (21), 7881-7890. doi: 10.1039/d2nr00183g

Graphene oxide as a dual template for induced helicity of peptides

2020

Journal Article

Convenient synthesis of thioamidated peptides and proteins

Khatri, Bhavesh, Bhat, Prabhat and Chatterjee, Jayanta (2020). Convenient synthesis of thioamidated peptides and proteins. Journal of Peptide Science, 26 (4-5) e3248, 1-9. doi: 10.1002/psc.3248

Convenient synthesis of thioamidated peptides and proteins

2018

Journal Article

Increasing the bioactive space of peptide macrocycles by thioamide substitution

Verma, Hitesh, Khatri, Bhavesh, Chakraborti, Sohini and Chatterjee, Jayanta (2018). Increasing the bioactive space of peptide macrocycles by thioamide substitution. Chemical Science, 9 (9), 2443-2451. doi: 10.1039/c7sc04671e

Increasing the bioactive space of peptide macrocycles by thioamide substitution

2015

Journal Article

Solution structural features of N-acyl homoserine lactones

Tumminakatti, Shama, Khatri, Bhavesh, Krishnamurti, Vinayak, Athavale, Vishikh and Prabhakaran, Erode N. (2015). Solution structural features of N-acyl homoserine lactones. Tetrahedron Letters, 56 (42), 5771-5775. doi: 10.1016/j.tetlet.2015.08.078

Solution structural features of N-acyl homoserine lactones