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2025 Journal Article Innate immune sensors and cell death—frontiers coordinating homeostasis, immunity, and inflammation in skinSoe, Ye Mon, Sim, Seen Ling and Kumari, Snehlata (2025). Innate immune sensors and cell death—frontiers coordinating homeostasis, immunity, and inflammation in skin. Viruses, 17 (2) 241. doi: 10.3390/v17020241 |
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2024 Journal Article Distinct roles of SOX9 in self-renewal of progenitors and mesenchymal transition of the endotheliumZhao, Jilai, Sormani, Laura, Jacquelin, Sebastien, Li, Haiming, Styke, Cassandra, Zhou, Chenhao, Beesley, Jonathan, Oon, Linus, Kaur, Simranpreet, Sim, Seen-Ling, Wong, Ho Yi, Dight, James, Hashemi, Ghazaleh, Shafiee, Abbas, Roy, Edwige, Patel, Jatin and Khosrotehrani, Kiarash (2024). Distinct roles of SOX9 in self-renewal of progenitors and mesenchymal transition of the endothelium. Angiogenesis, 27 (3), 1-16. doi: 10.1007/s10456-024-09927-7 |
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2022 Journal Article Macrophages in skin wounds: functions and therapeutic potentialSim, Seen Ling, Kumari, Snehlata, Kaur, Simranpreet and Khosrotehrani, Kiarash (2022). Macrophages in skin wounds: functions and therapeutic potential. Biomolecules, 12 (11) 1659, 1-31. doi: 10.3390/biom12111659 |
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2022 Journal Article Myeloid Wls expression is dispensable for skin wound healing and blood vessel regenerationSim, Seen Ling, Blumenthal, Antje, Kaur, Simranpreet and Khosrotehrani, Kiarash (2022). Myeloid Wls expression is dispensable for skin wound healing and blood vessel regeneration. Frontiers in Endocrinology, 13 957833, 957833. doi: 10.3389/fendo.2022.957833 |
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2022 Journal Article High-yield isolation of pure fetal endothelial colony forming cells and mesenchymal stem cells from the human full-term placentaNano, Rachel, Sim, Seen Ling, Shafiee, Abbas, Khosrotehrani, Kiarash and Patel, Jatin (2022). High-yield isolation of pure fetal endothelial colony forming cells and mesenchymal stem cells from the human full-term placenta. STAR Protocols, 3 (2) 101354, 101354. doi: 10.1016/j.xpro.2022.101354 |
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2021 Journal Article Combination of human endothelial colony-forming cells and mesenchymal stromal cells exert neuroprotective effects in the growth-restricted newbornChand, Kirat K., Patel, Jatin, Bjorkman, S. T., Sim, Seen-Ling, Miller, Stephanie M., Teo, Elliot, Jones, Lara, Sun, Jane, Colditz, Paul B., Khosrotehrani, Kiarash and Wixey, Julie A. (2021). Combination of human endothelial colony-forming cells and mesenchymal stromal cells exert neuroprotective effects in the growth-restricted newborn. npj Regenerative Medicine, 6 (1) 75, 75. doi: 10.1038/s41536-021-00185-5 |
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2021 Journal Article Subtype specific analyses reveal infiltrative basal cell carcinoma are highly interactive with their environmentVillani, Rehan, Murigneux, Valentine, Alexis, Josue, Sim, Seen-Ling, Wagels, Michael, Saunders, Nicholas, Soyer, H. Peter, Parmentier, Laurent, Nikolaev, Sergey, Fink, J. Lynn, Roy, Edwige and Khosrotehrani, Kiarash (2021). Subtype specific analyses reveal infiltrative basal cell carcinoma are highly interactive with their environment. The Journal of Investigative Dermatology, 141 (10), 2380-2390. doi: 10.1016/j.jid.2021.02.760 |
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2021 Journal Article Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitorsZhao, Jilai, Patel, Jatin, Kaur, Simranpreet, Sim, Seen-Ling, Wong, Ho Yi, Styke, Cassandra, Hogan, Isabella, Kahler, Sam, Hamilton, Hamish, Wadlow, Racheal, Dight, James, Hashemi, Ghazaleh, Sormani, Laura, Roy, Edwige, Yoder, Mervin C., Francois, Mathias and Khosrotehrani, Kiarash (2021). Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitors. Nature Communications, 12 (1) 2564, 1-17. doi: 10.1038/s41467-021-22717-9 |
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2020 Journal Article Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal ProgenitorsRoy, Edwige, Wong, Ho Yi, Villani, Rehan, Rouille, Thomas, Salik, Basit, Sim, Seen Ling, Murigneux, Valentine, Stark, Mitchell S., Fink, J. Lynn, Soyer, H. Peter, Walker, Graeme, Lyons, J. Guy, Saunders, Nicholas and Khosrotehrani, Kiarash (2020). Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors. Cell Reports, 31 (9) 107702, 107702. doi: 10.1016/j.celrep.2020.107702 |
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2020 Journal Article Ectopic expression of SOX18 in Basal cell carcinoma negatively regulates tumour progressionVillani, Rehan, Sim, Seen Ling, Roy, Edwige, Wainwright, Brandon, Francois, Mathias and Khosrotehrani, Kiarash (2020). Ectopic expression of SOX18 in Basal cell carcinoma negatively regulates tumour progression. Journal of Dermatological Science, 98 (3), 179-185. doi: 10.1016/j.jdermsci.2020.04.006 |
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2019 Journal Article Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cellsLukowski, Samuel W., Patel, Jatin, Andersen, Stacey B., Sim, Seen-Ling, Wong, Ho Yi, Tay, Joshua, Winkler, Ingrid, Powell, Joseph E. and Khosrotehrani, Kiarash (2019). Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells. Cell Reports, 27 (9), 2748-2758. doi: 10.1016/j.celrep.2019.04.102 |
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2019 Journal Article Abstract 576: Immunosuppression Agent Cyclosporine Reduces Self-Renewal and Vessel Regeneration Potentiation of Human Endothelial Colony Forming CellsSim, Seen-Ling, Alexis, Josue, Shafiee, Abbas, Khosrotehrani, Kiarash and Patel, Jatin (2019). Abstract 576: Immunosuppression Agent Cyclosporine Reduces Self-Renewal and Vessel Regeneration Potentiation of Human Endothelial Colony Forming Cells. Arteriosclerosis, Thrombosis, and Vascular Biology, 39 (Suppl_1). doi: 10.1161/atvb.39.suppl_1.576 |
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2019 Journal Article Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasisDonovan, Prudence, Patel, Jatin, Dight, James, Wong, Ho Yi, Sim, Seen-Ling, Murigneux, Valentine, Francois, Mathias and Khosrotehrani, Kiarash (2019). Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis. Nature Communications, 10 (1) 18, 18. doi: 10.1038/s41467-018-07961-w |
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2018 Journal Article Immunosuppression agent cyclosporine reduces self-renewal and vessel regeneration potentiation of human endothelial colony forming cells: deleterious effect of cyclosporine on ECFCSim, Seen-Ling, Alexis, Josue, Roy, Edwige, Shafiee, Abbas, Khosrotehrani, Kiarash and Patel, Jatin (2018). Immunosuppression agent cyclosporine reduces self-renewal and vessel regeneration potentiation of human endothelial colony forming cells: deleterious effect of cyclosporine on ECFC. STEM CELLS Translational Medicine, 8 (2), 162-168. doi: 10.1002/sctm.18-0103 |
