2025 Journal Article Innate immune sensors and cell death—frontiers coordinating homeostasis, immunity, and inflammation in skinSoe, Ye Mon, Sim, Seen Ling and Kumari, Snehlata (2025). Innate immune sensors and cell death—frontiers coordinating homeostasis, immunity, and inflammation in skin. Viruses, 17 (2) 241. doi: 10.3390/v17020241 |
2024 Journal Article Distinct roles of SOX9 in self-renewal of progenitors and mesenchymal transition of the endotheliumZhao, Jilai, Sormani, Laura, Jacquelin, Sebastien, Li, Haiming, Styke, Cassandra, Zhou, Chenhao, Beesley, Jonathan, Oon, Linus, Kaur, Simranpreet, Sim, Seen-Ling, Wong, Ho Yi, Dight, James, Hashemi, Ghazaleh, Shafiee, Abbas, Roy, Edwige, Patel, Jatin and Khosrotehrani, Kiarash (2024). Distinct roles of SOX9 in self-renewal of progenitors and mesenchymal transition of the endothelium. Angiogenesis, 27 (3), 1-16. doi: 10.1007/s10456-024-09927-7 |
2023 Other Outputs Deciphering the influence of macrophages on endothelial progenitorsSim, Seen Ling (2023). Deciphering the influence of macrophages on endothelial progenitors. PhD Thesis, Frazer Institute, The University of Queensland. doi: 10.14264/3483871 |
2023 Conference Publication 1511 Macrophages regulate endothelial progenitors’ quiescence and self-renewal during homeostasis and cutaneous wound healing via paracrine signalingSim, S., Kaur, S., Styke, C., Millard, S., Blumenthal, A., Pettit, A. and Khosrotehrani, K. (2023). 1511 Macrophages regulate endothelial progenitors’ quiescence and self-renewal during homeostasis and cutaneous wound healing via paracrine signaling. 1st International Societies for Investigative Dermatology Meeting, Tokyo, Japan, 10 - 13 May 2023. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2023.03.1528 |
2023 Conference Publication PDGFRA-expressing endovascular progenitors contribute to differentiated endothelium of aorta and woundsStyke, C., Kaur, S., Sim, S., Zhao, J., Shafiee, A., Zhou, C., Wong, H. and Khosrotehrani, K. (2023). PDGFRA-expressing endovascular progenitors contribute to differentiated endothelium of aorta and wounds. 1st International Societies for Investigative Dermatology Meeting, Tokyo, Japan, 10 - 13 May 2023. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2023.03.1476 |
2022 Journal Article Macrophages in skin wounds: functions and therapeutic potentialSim, Seen Ling, Kumari, Snehlata, Kaur, Simranpreet and Khosrotehrani, Kiarash (2022). Macrophages in skin wounds: functions and therapeutic potential. Biomolecules, 12 (11) 1659, 1-31. doi: 10.3390/biom12111659 |
2022 Journal Article Myeloid Wls expression is dispensable for skin wound healing and blood vessel regenerationSim, Seen Ling, Blumenthal, Antje, Kaur, Simranpreet and Khosrotehrani, Kiarash (2022). Myeloid Wls expression is dispensable for skin wound healing and blood vessel regeneration. Frontiers in Endocrinology, 13 957833, 957833. doi: 10.3389/fendo.2022.957833 |
2022 Journal Article High-yield isolation of pure fetal endothelial colony forming cells and mesenchymal stem cells from the human full-term placentaNano, Rachel, Sim, Seen Ling, Shafiee, Abbas, Khosrotehrani, Kiarash and Patel, Jatin (2022). High-yield isolation of pure fetal endothelial colony forming cells and mesenchymal stem cells from the human full-term placenta. STAR Protocols, 3 (2) 101354, 101354. doi: 10.1016/j.xpro.2022.101354 |
2021 Journal Article Combination of human endothelial colony-forming cells and mesenchymal stromal cells exert neuroprotective effects in the growth-restricted newbornChand, Kirat K., Patel, Jatin, Bjorkman, S. T., Sim, Seen-Ling, Miller, Stephanie M., Teo, Elliot, Jones, Lara, Sun, Jane, Colditz, Paul B., Khosrotehrani, Kiarash and Wixey, Julie A. (2021). Combination of human endothelial colony-forming cells and mesenchymal stromal cells exert neuroprotective effects in the growth-restricted newborn. npj Regenerative Medicine, 6 (1) 75, 75. doi: 10.1038/s41536-021-00185-5 |
2021 Journal Article Subtype specific analyses reveal infiltrative basal cell carcinoma are highly interactive with their environmentVillani, Rehan, Murigneux, Valentine, Alexis, Josue, Sim, Seen-Ling, Wagels, Michael, Saunders, Nicholas, Soyer, H. Peter, Parmentier, Laurent, Nikolaev, Sergey, Fink, J. Lynn, Roy, Edwige and Khosrotehrani, Kiarash (2021). Subtype specific analyses reveal infiltrative basal cell carcinoma are highly interactive with their environment. The Journal of Investigative Dermatology, 141 (10), 2380-2390. doi: 10.1016/j.jid.2021.02.760 |
2021 Journal Article Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitorsZhao, Jilai, Patel, Jatin, Kaur, Simranpreet, Sim, Seen-Ling, Wong, Ho Yi, Styke, Cassandra, Hogan, Isabella, Kahler, Sam, Hamilton, Hamish, Wadlow, Racheal, Dight, James, Hashemi, Ghazaleh, Sormani, Laura, Roy, Edwige, Yoder, Mervin C., Francois, Mathias and Khosrotehrani, Kiarash (2021). Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitors. Nature Communications, 12 (1) 2564, 1-17. doi: 10.1038/s41467-021-22717-9 |
2020 Journal Article Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal ProgenitorsRoy, Edwige, Wong, Ho Yi, Villani, Rehan, Rouille, Thomas, Salik, Basit, Sim, Seen Ling, Murigneux, Valentine, Stark, Mitchell S., Fink, J. Lynn, Soyer, H. Peter, Walker, Graeme, Lyons, J. Guy, Saunders, Nicholas and Khosrotehrani, Kiarash (2020). Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors. Cell Reports, 31 (9) 107702, 107702. doi: 10.1016/j.celrep.2020.107702 |
2020 Journal Article Ectopic expression of SOX18 in Basal cell carcinoma negatively regulates tumour progressionVillani, Rehan, Sim, Seen Ling, Roy, Edwige, Wainwright, Brandon, Francois, Mathias and Khosrotehrani, Kiarash (2020). Ectopic expression of SOX18 in Basal cell carcinoma negatively regulates tumour progression. Journal of Dermatological Science, 98 (3), 179-185. doi: 10.1016/j.jdermsci.2020.04.006 |
2019 Journal Article Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cellsLukowski, Samuel W., Patel, Jatin, Andersen, Stacey B., Sim, Seen-Ling, Wong, Ho Yi, Tay, Joshua, Winkler, Ingrid, Powell, Joseph E. and Khosrotehrani, Kiarash (2019). Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells. Cell Reports, 27 (9), 2748-2758. doi: 10.1016/j.celrep.2019.04.102 |
2019 Journal Article Abstract 576: Immunosuppression Agent Cyclosporine Reduces Self-Renewal and Vessel Regeneration Potentiation of Human Endothelial Colony Forming CellsSim, Seen-Ling, Alexis, Josue, Shafiee, Abbas, Khosrotehrani, Kiarash and Patel, Jatin (2019). Abstract 576: Immunosuppression Agent Cyclosporine Reduces Self-Renewal and Vessel Regeneration Potentiation of Human Endothelial Colony Forming Cells. Arteriosclerosis, Thrombosis, and Vascular Biology, 39 (Suppl_1). doi: 10.1161/atvb.39.suppl_1.576 |
2019 Journal Article Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasisDonovan, Prudence, Patel, Jatin, Dight, James, Wong, Ho Yi, Sim, Seen-Ling, Murigneux, Valentine, Francois, Mathias and Khosrotehrani, Kiarash (2019). Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis. Nature Communications, 10 (1) 18, 18. doi: 10.1038/s41467-018-07961-w |
2019 Conference Publication Cancer associated fibroblast profiling reveals endothelin signalling as a novel mediator of niche to tumour cross-talk in Basal Cell CarcinomaVillani, R., Roy, E., Murigneux, V., Sim, S., Malapitan, C., Galbraith, J., Kapadia, S., Fink, L. and Khosrotehrani, K. (2019). Cancer associated fibroblast profiling reveals endothelin signalling as a novel mediator of niche to tumour cross-talk in Basal Cell Carcinoma. 49th Annual Meeting of the European Society for Dermatological Research (ESDR), Bordeaux, France, 18-21 September 2019. New York, NY United States: Elsevier. doi: 10.1016/j.jid.2019.07.507 |
2019 Conference Publication Changing endothelial cell fate in wound healing through modulation of Sox9 to reduce scarringPatel, J., Hamilton, H., Kahler, S., Sim, S., Wong, H. and Khosrotehrani, K. (2019). Changing endothelial cell fate in wound healing through modulation of Sox9 to reduce scarring. 49th Annual Meeting of the European Society for Dermatological Research (ESDR), Bordeaux, France, 18-21 September, 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2019.07.628 |
2018 Journal Article Immunosuppression agent cyclosporine reduces self-renewal and vessel regeneration potentiation of human endothelial colony forming cells: deleterious effect of cyclosporine on ECFCSim, Seen-Ling, Alexis, Josue, Roy, Edwige, Shafiee, Abbas, Khosrotehrani, Kiarash and Patel, Jatin (2018). Immunosuppression agent cyclosporine reduces self-renewal and vessel regeneration potentiation of human endothelial colony forming cells: deleterious effect of cyclosporine on ECFC. STEM CELLS Translational Medicine, 8 (2), 162-168. doi: 10.1002/sctm.18-0103 |
2016 Conference Publication Basal cell carcinoma development is promoted by ablation of the dermal papilla mesenchymal nicheVillani, R., Sim, S. L., Greaney, J., Wainwright, B. and Khosrotehrani, K. (2016). Basal cell carcinoma development is promoted by ablation of the dermal papilla mesenchymal niche. Asia-Pacific Combined Dermatology Research Conference 2016, Noosa, QLD, Australia, 25–28 August 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.12584 |