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2024

Conference Publication

Multiomics Analysis of Paired Diagnosis and Relapse DLBCL Biopsies Shows a Reduction in T Cell Infiltration and Function at Relapse

Swain, Fiona, Burgess, Melinda, Kempe, Sarah, Sabdia, Muhammed B., Henden, Andrea S., Wight, Joel, Hawkes, Eliza A., Mutsando, Howard, Talaulikar, Dipti, Merida de Long, Lilia, Birch, Simone, Wyche, Penelope, Hawula, Zachary, Chowdhury, Rakin, Gandhi, Maher K. and Keane, Colm (2024). Multiomics Analysis of Paired Diagnosis and Relapse DLBCL Biopsies Shows a Reduction in T Cell Infiltration and Function at Relapse. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-199352

Multiomics Analysis of Paired Diagnosis and Relapse DLBCL Biopsies Shows a Reduction in T Cell Infiltration and Function at Relapse

2023

Conference Publication

High Frequency of HLA-Class II B Cell Receptor Neoantigens in IGHV Mutated-CLL

Sabdia, Muhammed B., Burgess, Melinda, Law, Soi Cheng, Thurgood, Lauren A., Kazakoff, Stephen, Swain, Fiona, Tobin, Joshua W.D., Mollee, Peter, Patch, Ann-Marie and Gandhi, Maher K (2023). High Frequency of HLA-Class II B Cell Receptor Neoantigens in IGHV Mutated-CLL. 65th ASH Annual Meeting, San Diego, CA United States, 9-12 December 2023. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2023-174149

High Frequency of HLA-Class II B Cell Receptor Neoantigens in IGHV Mutated-CLL

2023

Conference Publication

Final Analysis Of Australasian Leukaemia & Lymphoma Group NHL29: A Phase II Study Of Ibrutinib, Rituximab And Mini-chop In Very Elderly Patients With Newly Diagnosed DLBCL

Verner, Emma, Johnston, Amanda, Pati, Nalini, Hawkes, Eliza, Peng Lee, Hui, Cochrane, Tara, Yoon Cheah, Chan, Filshie, Robin, Purtill, Duncan, Sia, Hanlon, Enjeti, Anoop K, Brown, Christina, Murphy, Nicholas, Curnow, Jennifer, Lee, Kenneth, Gandhi, Maher, Butcher, Belinda and Trotman, Judith (2023). Final Analysis Of Australasian Leukaemia & Lymphoma Group NHL29: A Phase II Study Of Ibrutinib, Rituximab And Mini-chop In Very Elderly Patients With Newly Diagnosed DLBCL. EHA2023, Online, 8 - 15 June 2023. Philadelphia, PA United States: Wolters Kluwer. doi: 10.1097/01.hs9.0000971404.12997.4b

Final Analysis Of Australasian Leukaemia & Lymphoma Group NHL29: A Phase II Study Of Ibrutinib, Rituximab And Mini-chop In Very Elderly Patients With Newly Diagnosed DLBCL

2023

Conference Publication

Gene expression and spatial transcriptomic analysis of paired diagnosis and relapse DLBCL biopsies show a reduction in T cell infiltration and function at relapse

Swain, F., Burgess, M., Kempe, S., Sabdia, M., Wight, J., Hawkes, E., Mutsando, H., Talaulikar, D., Merida de Long, L., Hawula, Z., Birch, S., Wyche, P., Gandhi, M. K. and Keane, C. (2023). Gene expression and spatial transcriptomic analysis of paired diagnosis and relapse DLBCL biopsies show a reduction in T cell infiltration and function at relapse. 17th International Conference on Malignant Lymphoma, Lugano, Switzerland, 13 - 17 June 2023. Chichester, West Sussex United Kingdom: Wiley-Blackwell. doi: 10.1002/hon.3164_191

Gene expression and spatial transcriptomic analysis of paired diagnosis and relapse DLBCL biopsies show a reduction in T cell infiltration and function at relapse

2023

Conference Publication

Final analysis of Australasian Leukaemia & Lymphoma Group NHL29: A phase II study of ibrutinib, rituximab and mini‐CHOP in very elderly patients with newly diagnosed DLBCL

Verner, E., Johnston, A., Pati, N., Hawkes, E., Lee, H. P., Cochrane, T., Cheah, C. Y., Filshie, R., Purtill, D., Sia, H., Enjeti, A. K., Brown, C., Murphy, N., Curnow, J., Lee, K., Gandhi, M. K., Butcher, B. E. and Trotman, J. (2023). Final analysis of Australasian Leukaemia & Lymphoma Group NHL29: A phase II study of ibrutinib, rituximab and mini‐CHOP in very elderly patients with newly diagnosed DLBCL. 17th International Conference on Malignant Lymphoma, Lugano, Switzerland, 13 - 17 June 2023. Chichester, West Sussex United Kingdom: Wiley-Blackwell. doi: 10.1002/hon.3164_313

Final analysis of Australasian Leukaemia & Lymphoma Group NHL29: A phase II study of ibrutinib, rituximab and mini‐CHOP in very elderly patients with newly diagnosed DLBCL

2023

Conference Publication

Prognostic impact of HLA‐I neoantigen‐specific CD8+ T cells in limited‐stage follicular lymphoma

Tobin, J. W., Tsang, H., Patch, A., Keane, C., Law, S. C., Gunawardana, J., Blombery, P., Thompson, E. R., Sabdia, M. B., De Long, L. M., Nath, K., Kazakoff, S. H., Cheah, C., Amanuel, B., Cochrane, T., Butler, J., Johnston, A., Shanavas, M., Li, L., Shelton, V., Hershenfeld, S., Kridel, R., Seymour, J. F., MacManus, M. and Gandhi, M. K. (2023). Prognostic impact of HLA‐I neoantigen‐specific CD8+ T cells in limited‐stage follicular lymphoma. 17th International Conference on Malignant Lymphoma, Lugano, Switzerland, 13 - 17 June 2023. Chichester, West Sussex United Kingdom: Wiley-Blackwell. doi: 10.1002/hon.3164_189

Prognostic impact of HLA‐I neoantigen‐specific CD8+ T cells in limited‐stage follicular lymphoma

2023

Conference Publication

Rituximab‐containing combined modality therapy in limited stage follicular lymphoma: mature follow up and derivation of a novel prognostic score from the TROG99.03 trial

Tobin, J. W., Jurinovic, V., Tsang, H., Roos, D., Tsang, R., Macann, A., Davis, S., Christie, D., Law, S., Nath, K., Sabdia, M., Patch, A. M., Gunawardana, J., Merida de Long, L., Hoster, E., Horn, H., Shanavas, M., Li, L., Cheah, C., Benhur, A., Hou, M., O'Brien, P., Johnston, A. M., Cochrane, T., Butler, J., Thompson, E., Blombery, P., Seymour, J. F., Gandhi, M. K. and MacManus, M. (2023). Rituximab‐containing combined modality therapy in limited stage follicular lymphoma: mature follow up and derivation of a novel prognostic score from the TROG99.03 trial. 17th International Conference on Malignant Lymphoma, Lugano, Switzerland, 13-17 June 2023. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/hon.3163_140

Rituximab‐containing combined modality therapy in limited stage follicular lymphoma: mature follow up and derivation of a novel prognostic score from the TROG99.03 trial

2023

Conference Publication

ANALYSIS OF THE GENETIC LANDSCAPE IN ELDERLY DIFFUSE LARGE B CELL LYMPHOMA AGED ≥ 75 YEARS IDENTIFIES NEW TARGETABLE MUTATIONS

Rijal, Sewa, Lim, Jun Hee, Smyth, Lillian, Coombes, Caitlin, Jain, Sanjiv, Saxena, Kartik, Trotman, Judith, Verner, Emma, Gandhi, Maher K., Gandhi, Kaushal and Talaulikar, Dipti (2023). ANALYSIS OF THE GENETIC LANDSCAPE IN ELDERLY DIFFUSE LARGE B CELL LYMPHOMA AGED ≥ 75 YEARS IDENTIFIES NEW TARGETABLE MUTATIONS. HOBOKEN: WILEY.

ANALYSIS OF THE GENETIC LANDSCAPE IN ELDERLY DIFFUSE LARGE B CELL LYMPHOMA AGED ≥ 75 YEARS IDENTIFIES NEW TARGETABLE MUTATIONS

2022

Conference Publication

FLIPI24: An Improved International Prognostic Model Developed on Early Events in Follicular Lymphoma

Maurer, Matthew J., Prochazka, Vit K., Flowers, Christopher R., Jakobsen, Lasse Hjort, Villa, Diego, Weibull, Caroline E., Cahn, Elliot J., Smith, Alexandra, Ghesquieres, Herve, Kridel, Robert, Gandhi, Maher, Cheah, Chan Y., Hawkes, Eliza, Seymour, John F., Freeman, Ciara L., Clausen, Michael Roost, Wahlin, Bjorn E., Friedberg, Jonathan W., Casulo, Carla, Habermann, Thomas M., Wang, Yucai, Nastoupil, Loretta J., Brown, Peter De Nully, Belada, David, Janikova, Andrea, Mocikova, Heidi, Furst, Tomas, Burack, Richard, Martin, Peter ... Cerhan, James R. (2022). FLIPI24: An Improved International Prognostic Model Developed on Early Events in Follicular Lymphoma. 64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), New Orleans La, Dec 10-13, 2022. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2022-157194

FLIPI24: An Improved International Prognostic Model Developed on Early Events in Follicular Lymphoma

2022

Conference Publication

Comparative Analysis of Genome-Scale Gene Regulatory Networks in Human Hematopoietic Stem and Myeloid Progenitor Fractions

Subramanian, Shruthi, Thoms, Julie A., Huang, Yizhou, Jacquelin, Sebastien, Shen, Sylvie, Song, Emma, Joshi, Swapna, Brownlee, Chris, Woll, Petter S., Fajardo, Diego Chacon, Beck, Dominik, Curtis, David J., Yehson, Kenneth, Antonenas, Vicki, O' Brien, Tracey, Trickett, Annette, Powell, Jason, Pitson, Stuart M., Gandhi, Maher K., Cornejo, Paola, Wong, Emily, Lane, Steven W., Gottgens, Bertie, Rokny, Hamid Alinejad, Wong, Jason W. H. and Pimanda, John E. (2022). Comparative Analysis of Genome-Scale Gene Regulatory Networks in Human Hematopoietic Stem and Myeloid Progenitor Fractions. 64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), New Orleans La, Dec 10-13, 2022. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2022-165620

Comparative Analysis of Genome-Scale Gene Regulatory Networks in Human Hematopoietic Stem and Myeloid Progenitor Fractions

2022

Conference Publication

Identification of Genetic Subtypes in Follicular Lymphoma

Shelton, Victoria, Isaev, Keren, Liu, Ting, Silva, Anjali, Detroja, Rajesh, Bakhtiari, Mehran, Calvente, Lourdes, Hong, Michael, Modi, Saloni, Hershenfeld, Samantha A., Ludvigsen, Maja, d'Amore, Francesco Annibale, Brodtkorb, Marianne, Johnson, Nathalie A., Baetz, Tara, LeBrun, David, Tobin, Josh, Gandhi, Maher K., Mungall, Andrew J., Steidl, Christian, Delabie, Jan, Tremblay-Lemay, Rosemarie, Kahl, Brad S., Evens, Andrew M and Kridel, Robert (2022). Identification of Genetic Subtypes in Follicular Lymphoma. 64th ASH Annual Meeting, New Orleans, LA United States, 10-13 December 2022. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2022-164610

Identification of Genetic Subtypes in Follicular Lymphoma

2022

Conference Publication

Abstract A17: the immune checkpoints TIGIT and PD-1 are markedly upregulated in NLPHL compared to classical Hodgkin Lymphoma

Gunawardana, Jay, Law, Soi C., Sabdia, Muhammed B., Bednarska, Karolina, Brosda, Sandra, Zaharia, Andreea, Tsang, Hennes, de Long, Lilia M., Burgess, Melinda, Talaulikar, Dipti, Lee, Justina N., Jude, Emily, Hawkes, Eliza A., Jain, Sanjiv, Nath, Karthik, Gould, Clare, Swain, Fiona, Tobin, Joshua W. D., Keane, Colm, Birch, Simone, Shanavas, Mohamed, Snell, Cameron and Gandhi, Maher K. (2022). Abstract A17: the immune checkpoints TIGIT and PD-1 are markedly upregulated in NLPHL compared to classical Hodgkin Lymphoma. Third AACR International Meeting: Advances in Malignant Lymphoma: Maximizing the Basic-Translational Interface for Clinical Application, 23-25 June 2022, Boston, MA USA. Philadelphia, PA USA: American Association for Cancer Research. doi: 10.1158/2643-3249.lymphoma22-a17

Abstract A17: the immune checkpoints TIGIT and PD-1 are markedly upregulated in NLPHL compared to classical Hodgkin Lymphoma

2021

Conference Publication

The NLPHL Tumor Microenvironment Is Markedly Enriched in the Tigit and PD-1 Signalling Axes Compared to Classical Hodgkin Lymphoma

Gunawardana, Jay, Sabdia, Muhammed B., Bednarska, Karolina, Law, Soi C., Brosda, Sandra, Tsang, Hennes, De Long, Lilia Merida, Zaharia, Andreea, Lee, Justina, Jude, Emily, Hawkes, Eliza, Nath, Karthik, Gould, Clare, Burgess, Melinda Lea, Swain, Fiona, Tobin, Joshua W. D., Keane, Colm, Birch, Simone, Talaulikar, Dipti, Jain, Sanjiv, Shanavas, Mohamed, Snell, Cameron and Gandhi, Maher (2021). The NLPHL Tumor Microenvironment Is Markedly Enriched in the Tigit and PD-1 Signalling Axes Compared to Classical Hodgkin Lymphoma. 63rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta Ga, Dec 11-14, 2021. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2021-145840

The NLPHL Tumor Microenvironment Is Markedly Enriched in the Tigit and PD-1 Signalling Axes Compared to Classical Hodgkin Lymphoma

2021

Conference Publication

Lenalidomide Consolidation Added to Rituximab Maintenance Therapy in Patients Remaining PET Positive after Treatment for Relapsed Follicular Lymphoma: Phase 2 Australasian Leukaemia & Lymphoma Group NHL26 Study

Trotman, Judith, Presgrave, Peter, Carradice, Duncan P., Lenton, Douglas Stuart, Gandhi, Maher, Cochrane, Tara, Badoux, Xavier, NKhoma, Gloria, Butcher, Belinda, Fulham, Michael and Johnston, Anna (2021). Lenalidomide Consolidation Added to Rituximab Maintenance Therapy in Patients Remaining PET Positive after Treatment for Relapsed Follicular Lymphoma: Phase 2 Australasian Leukaemia & Lymphoma Group NHL26 Study. 63rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta Ga, Dec 11-14, 2021. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2021-146343

Lenalidomide Consolidation Added to Rituximab Maintenance Therapy in Patients Remaining PET Positive after Treatment for Relapsed Follicular Lymphoma: Phase 2 Australasian Leukaemia & Lymphoma Group NHL26 Study

2020

Conference Publication

A cost-effectiveness analysis of front-line treatment strategies in early stage follicular lymphoma

Tobin, Joshua W.D., Hapgood, Greg, Gandhi, Maher K., Mollee, Peter, Ma, Ti, Crothers, Anna and Scuffham, Paul (2020). A cost-effectiveness analysis of front-line treatment strategies in early stage follicular lymphoma. 62nd ASH Annual Meeting and Exposition, Online, 5-8 December 2020. Washington, DC USA: American Society of Hematology. doi: 10.1182/blood-2020-138590

A cost-effectiveness analysis of front-line treatment strategies in early stage follicular lymphoma

2020

Conference Publication

Neoantigens are typically associated with intact HLA class I presentation in early-stage follicular lymphoma

Tsang, Hennes, Patch, Ann-Marie, Keane, Colm, Law, Soi C., Gunawardana, Jay, Blombery, Piers, Thompson, Ella R., Sabdia, Muhammed B., De Long, Lilia Merida, Belle, Clemence J., Nath, Karthik, Tobin, Joshua W.D., Kazakoff, Stephen H., Seymour, John F., MacManus, Michael and Gandhi, Maher K. (2020). Neoantigens are typically associated with intact HLA class I presentation in early-stage follicular lymphoma. 62nd ASH Annual Meeting and Exposition, Online, 5-8 December 2020. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2020-135954

Neoantigens are typically associated with intact HLA class I presentation in early-stage follicular lymphoma

2019

Conference Publication

Intra-tumoral CD8+T-cells in follicular lymphoma contain large clonal expansions that are amenable to dual-checkpoint blockade

Nath, Karthik, Law, Soi C., Sabdia, Muhammed B., De Long, Lilia Merida, Shanavas, Mohamed, Tobin, Joshua W. D., Gunawardana, Jay, Vari, Frank, Halliday, Sarah-Jane, Hernandez, Annette, Cross, Donna, Bird, Robert J., Keane, Colm and Gandhi, Maher K. (2019). Intra-tumoral CD8+T-cells in follicular lymphoma contain large clonal expansions that are amenable to dual-checkpoint blockade. 61st Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Orlando, FL, United States, 7 - 10 December 2019. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2019-130050

Intra-tumoral CD8+T-cells in follicular lymphoma contain large clonal expansions that are amenable to dual-checkpoint blockade

2019

Conference Publication

EBV+ CNS lymphomas have a distinctive tumor microenvironment and genetic profile, which is amenable to combination 3rd party EBV-specific CTL and Ibrutinib therapy

Gandhi, M.K., Hoang, T., Tobin, J.W., Law, S.C., Talaulikar, D., Jain, S., Vari, F., Murigneux, V., Fink, L., Gunawardana, J., Gould, C., Oey, H., Delecluse, S., Trappe, R.U., Merida de Long, L., Sabdia, M.B., Bhagat, G., Hapgood, G., Blyth, E., Clancy, L., Casey, J., Wight, J., Hawkes, E. and Keane, C. (2019). EBV+ CNS lymphomas have a distinctive tumor microenvironment and genetic profile, which is amenable to combination 3rd party EBV-specific CTL and Ibrutinib therapy. 15th International Conference on Malignant Lymphoma, Lugano, Switzerland, 18–22 June 2019. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/hon.91_2629

EBV+ CNS lymphomas have a distinctive tumor microenvironment and genetic profile, which is amenable to combination 3rd party EBV-specific CTL and Ibrutinib therapy

2019

Conference Publication

B2M Gene Expression Reflects an Immunologically Active Tumor Microenvironment in DLBCL

Gould, Clare, Keane, Colm, Murigneux, Valentine, Oey, Harald, Ellis, Jonathan, Birch, Simone, Gunawardana, Jay, Talaulikar, Dipti, Hertzberg, Mark S., Jones, Kimberley and Gandhi, Maher K. (2019). B2M Gene Expression Reflects an Immunologically Active Tumor Microenvironment in DLBCL. ASH Annual Meeting, Orlando, FL, United States, 7-10 December 2019. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2019-126537

B2M Gene Expression Reflects an Immunologically Active Tumor Microenvironment in DLBCL

2018

Conference Publication

A critical role for intratumoral and circulating LAG3 in classical Hodgkin Lymphoma: analysis from the Rathl prospective phase III international clinical trial

Abro, Emad Uddin, Law, Soi C., Keane, Colm, Birch, Simone, Sabdia, Muhammed Bilal, Tobin, Joshua W. D., Johnson, Peter, Trotman, Judith, Berkahn, Leanne, Fulham, Michael, Anderson, Richard A., Saunderson, Anne L., Gunawardana, Jay, Cross, Donna, Hernandez, Annette, Halliday, Sarah-Jane, Bird, Robert, Law, W. P., Gill, Devinder and Gandhi, Maher K. (2018). A critical role for intratumoral and circulating LAG3 in classical Hodgkin Lymphoma: analysis from the Rathl prospective phase III international clinical trial. 60th ASH Annual Meeting, San Diego, CA United States, 1-4 December 2020. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2018-99-112008

A critical role for intratumoral and circulating LAG3 in classical Hodgkin Lymphoma: analysis from the Rathl prospective phase III international clinical trial