2024 Conference Publication Multiomics Analysis of Paired Diagnosis and Relapse DLBCL Biopsies Shows a Reduction in T Cell Infiltration and Function at RelapseSwain, Fiona, Burgess, Melinda, Kempe, Sarah, Sabdia, Muhammed B., Henden, Andrea S., Wight, Joel, Hawkes, Eliza A., Mutsando, Howard, Talaulikar, Dipti, Merida de Long, Lilia, Birch, Simone, Wyche, Penelope, Hawula, Zachary, Chowdhury, Rakin, Gandhi, Maher K. and Keane, Colm (2024). Multiomics Analysis of Paired Diagnosis and Relapse DLBCL Biopsies Shows a Reduction in T Cell Infiltration and Function at Relapse. 66th ASH Annual Meeting, San Diego, CA United States, 7-10 December 2024. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2024-199352 |
2023 Conference Publication High Frequency of HLA-Class II B Cell Receptor Neoantigens in IGHV Mutated-CLLSabdia, Muhammed B., Burgess, Melinda, Law, Soi Cheng, Thurgood, Lauren A., Kazakoff, Stephen, Swain, Fiona, Tobin, Joshua W.D., Mollee, Peter, Patch, Ann-Marie and Gandhi, Maher K (2023). High Frequency of HLA-Class II B Cell Receptor Neoantigens in IGHV Mutated-CLL. 65th ASH Annual Meeting, San Diego, CA United States, 9-12 December 2023. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2023-174149 |
2023 Conference Publication Final Analysis Of Australasian Leukaemia & Lymphoma Group NHL29: A Phase II Study Of Ibrutinib, Rituximab And Mini-chop In Very Elderly Patients With Newly Diagnosed DLBCLVerner, Emma, Johnston, Amanda, Pati, Nalini, Hawkes, Eliza, Peng Lee, Hui, Cochrane, Tara, Yoon Cheah, Chan, Filshie, Robin, Purtill, Duncan, Sia, Hanlon, Enjeti, Anoop K, Brown, Christina, Murphy, Nicholas, Curnow, Jennifer, Lee, Kenneth, Gandhi, Maher, Butcher, Belinda and Trotman, Judith (2023). Final Analysis Of Australasian Leukaemia & Lymphoma Group NHL29: A Phase II Study Of Ibrutinib, Rituximab And Mini-chop In Very Elderly Patients With Newly Diagnosed DLBCL. EHA2023, Online, 8 - 15 June 2023. Philadelphia, PA United States: Wolters Kluwer. doi: 10.1097/01.hs9.0000971404.12997.4b |
2023 Conference Publication Gene expression and spatial transcriptomic analysis of paired diagnosis and relapse DLBCL biopsies show a reduction in T cell infiltration and function at relapseSwain, F., Burgess, M., Kempe, S., Sabdia, M., Wight, J., Hawkes, E., Mutsando, H., Talaulikar, D., Merida de Long, L., Hawula, Z., Birch, S., Wyche, P., Gandhi, M. K. and Keane, C. (2023). Gene expression and spatial transcriptomic analysis of paired diagnosis and relapse DLBCL biopsies show a reduction in T cell infiltration and function at relapse. 17th International Conference on Malignant Lymphoma, Lugano, Switzerland, 13 - 17 June 2023. Chichester, West Sussex United Kingdom: Wiley-Blackwell. doi: 10.1002/hon.3164_191 |
2023 Conference Publication Final analysis of Australasian Leukaemia & Lymphoma Group NHL29: A phase II study of ibrutinib, rituximab and mini‐CHOP in very elderly patients with newly diagnosed DLBCLVerner, E., Johnston, A., Pati, N., Hawkes, E., Lee, H. P., Cochrane, T., Cheah, C. Y., Filshie, R., Purtill, D., Sia, H., Enjeti, A. K., Brown, C., Murphy, N., Curnow, J., Lee, K., Gandhi, M. K., Butcher, B. E. and Trotman, J. (2023). Final analysis of Australasian Leukaemia & Lymphoma Group NHL29: A phase II study of ibrutinib, rituximab and mini‐CHOP in very elderly patients with newly diagnosed DLBCL. 17th International Conference on Malignant Lymphoma, Lugano, Switzerland, 13 - 17 June 2023. Chichester, West Sussex United Kingdom: Wiley-Blackwell. doi: 10.1002/hon.3164_313 |
2023 Conference Publication Prognostic impact of HLA‐I neoantigen‐specific CD8+ T cells in limited‐stage follicular lymphomaTobin, J. W., Tsang, H., Patch, A., Keane, C., Law, S. C., Gunawardana, J., Blombery, P., Thompson, E. R., Sabdia, M. B., De Long, L. M., Nath, K., Kazakoff, S. H., Cheah, C., Amanuel, B., Cochrane, T., Butler, J., Johnston, A., Shanavas, M., Li, L., Shelton, V., Hershenfeld, S., Kridel, R., Seymour, J. F., MacManus, M. and Gandhi, M. K. (2023). Prognostic impact of HLA‐I neoantigen‐specific CD8+ T cells in limited‐stage follicular lymphoma. 17th International Conference on Malignant Lymphoma, Lugano, Switzerland, 13 - 17 June 2023. Chichester, West Sussex United Kingdom: Wiley-Blackwell. doi: 10.1002/hon.3164_189 |
2023 Conference Publication Rituximab‐containing combined modality therapy in limited stage follicular lymphoma: mature follow up and derivation of a novel prognostic score from the TROG99.03 trialTobin, J. W., Jurinovic, V., Tsang, H., Roos, D., Tsang, R., Macann, A., Davis, S., Christie, D., Law, S., Nath, K., Sabdia, M., Patch, A. M., Gunawardana, J., Merida de Long, L., Hoster, E., Horn, H., Shanavas, M., Li, L., Cheah, C., Benhur, A., Hou, M., O'Brien, P., Johnston, A. M., Cochrane, T., Butler, J., Thompson, E., Blombery, P., Seymour, J. F., Gandhi, M. K. and MacManus, M. (2023). Rituximab‐containing combined modality therapy in limited stage follicular lymphoma: mature follow up and derivation of a novel prognostic score from the TROG99.03 trial. 17th International Conference on Malignant Lymphoma, Lugano, Switzerland, 13-17 June 2023. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/hon.3163_140 |
2023 Conference Publication ANALYSIS OF THE GENETIC LANDSCAPE IN ELDERLY DIFFUSE LARGE B CELL LYMPHOMA AGED ≥ 75 YEARS IDENTIFIES NEW TARGETABLE MUTATIONSRijal, Sewa, Lim, Jun Hee, Smyth, Lillian, Coombes, Caitlin, Jain, Sanjiv, Saxena, Kartik, Trotman, Judith, Verner, Emma, Gandhi, Maher K., Gandhi, Kaushal and Talaulikar, Dipti (2023). ANALYSIS OF THE GENETIC LANDSCAPE IN ELDERLY DIFFUSE LARGE B CELL LYMPHOMA AGED ≥ 75 YEARS IDENTIFIES NEW TARGETABLE MUTATIONS. HOBOKEN: WILEY. |
2022 Conference Publication FLIPI24: An Improved International Prognostic Model Developed on Early Events in Follicular LymphomaMaurer, Matthew J., Prochazka, Vit K., Flowers, Christopher R., Jakobsen, Lasse Hjort, Villa, Diego, Weibull, Caroline E., Cahn, Elliot J., Smith, Alexandra, Ghesquieres, Herve, Kridel, Robert, Gandhi, Maher, Cheah, Chan Y., Hawkes, Eliza, Seymour, John F., Freeman, Ciara L., Clausen, Michael Roost, Wahlin, Bjorn E., Friedberg, Jonathan W., Casulo, Carla, Habermann, Thomas M., Wang, Yucai, Nastoupil, Loretta J., Brown, Peter De Nully, Belada, David, Janikova, Andrea, Mocikova, Heidi, Furst, Tomas, Burack, Richard, Martin, Peter ... Cerhan, James R. (2022). FLIPI24: An Improved International Prognostic Model Developed on Early Events in Follicular Lymphoma. 64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), New Orleans La, Dec 10-13, 2022. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2022-157194 |
2022 Conference Publication Comparative Analysis of Genome-Scale Gene Regulatory Networks in Human Hematopoietic Stem and Myeloid Progenitor FractionsSubramanian, Shruthi, Thoms, Julie A., Huang, Yizhou, Jacquelin, Sebastien, Shen, Sylvie, Song, Emma, Joshi, Swapna, Brownlee, Chris, Woll, Petter S., Fajardo, Diego Chacon, Beck, Dominik, Curtis, David J., Yehson, Kenneth, Antonenas, Vicki, O' Brien, Tracey, Trickett, Annette, Powell, Jason, Pitson, Stuart M., Gandhi, Maher K., Cornejo, Paola, Wong, Emily, Lane, Steven W., Gottgens, Bertie, Rokny, Hamid Alinejad, Wong, Jason W. H. and Pimanda, John E. (2022). Comparative Analysis of Genome-Scale Gene Regulatory Networks in Human Hematopoietic Stem and Myeloid Progenitor Fractions. 64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), New Orleans La, Dec 10-13, 2022. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2022-165620 |
2022 Conference Publication Identification of Genetic Subtypes in Follicular LymphomaShelton, Victoria, Isaev, Keren, Liu, Ting, Silva, Anjali, Detroja, Rajesh, Bakhtiari, Mehran, Calvente, Lourdes, Hong, Michael, Modi, Saloni, Hershenfeld, Samantha A., Ludvigsen, Maja, d'Amore, Francesco Annibale, Brodtkorb, Marianne, Johnson, Nathalie A., Baetz, Tara, LeBrun, David, Tobin, Josh, Gandhi, Maher K., Mungall, Andrew J., Steidl, Christian, Delabie, Jan, Tremblay-Lemay, Rosemarie, Kahl, Brad S., Evens, Andrew M and Kridel, Robert (2022). Identification of Genetic Subtypes in Follicular Lymphoma. 64th ASH Annual Meeting, New Orleans, LA United States, 10-13 December 2022. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2022-164610 |
2022 Conference Publication Abstract A17: the immune checkpoints TIGIT and PD-1 are markedly upregulated in NLPHL compared to classical Hodgkin LymphomaGunawardana, Jay, Law, Soi C., Sabdia, Muhammed B., Bednarska, Karolina, Brosda, Sandra, Zaharia, Andreea, Tsang, Hennes, de Long, Lilia M., Burgess, Melinda, Talaulikar, Dipti, Lee, Justina N., Jude, Emily, Hawkes, Eliza A., Jain, Sanjiv, Nath, Karthik, Gould, Clare, Swain, Fiona, Tobin, Joshua W. D., Keane, Colm, Birch, Simone, Shanavas, Mohamed, Snell, Cameron and Gandhi, Maher K. (2022). Abstract A17: the immune checkpoints TIGIT and PD-1 are markedly upregulated in NLPHL compared to classical Hodgkin Lymphoma. Third AACR International Meeting: Advances in Malignant Lymphoma: Maximizing the Basic-Translational Interface for Clinical Application, 23-25 June 2022, Boston, MA USA. Philadelphia, PA USA: American Association for Cancer Research. doi: 10.1158/2643-3249.lymphoma22-a17 |
2021 Conference Publication The NLPHL Tumor Microenvironment Is Markedly Enriched in the Tigit and PD-1 Signalling Axes Compared to Classical Hodgkin LymphomaGunawardana, Jay, Sabdia, Muhammed B., Bednarska, Karolina, Law, Soi C., Brosda, Sandra, Tsang, Hennes, De Long, Lilia Merida, Zaharia, Andreea, Lee, Justina, Jude, Emily, Hawkes, Eliza, Nath, Karthik, Gould, Clare, Burgess, Melinda Lea, Swain, Fiona, Tobin, Joshua W. D., Keane, Colm, Birch, Simone, Talaulikar, Dipti, Jain, Sanjiv, Shanavas, Mohamed, Snell, Cameron and Gandhi, Maher (2021). The NLPHL Tumor Microenvironment Is Markedly Enriched in the Tigit and PD-1 Signalling Axes Compared to Classical Hodgkin Lymphoma. 63rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta Ga, Dec 11-14, 2021. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2021-145840 |
2021 Conference Publication Lenalidomide Consolidation Added to Rituximab Maintenance Therapy in Patients Remaining PET Positive after Treatment for Relapsed Follicular Lymphoma: Phase 2 Australasian Leukaemia & Lymphoma Group NHL26 StudyTrotman, Judith, Presgrave, Peter, Carradice, Duncan P., Lenton, Douglas Stuart, Gandhi, Maher, Cochrane, Tara, Badoux, Xavier, NKhoma, Gloria, Butcher, Belinda, Fulham, Michael and Johnston, Anna (2021). Lenalidomide Consolidation Added to Rituximab Maintenance Therapy in Patients Remaining PET Positive after Treatment for Relapsed Follicular Lymphoma: Phase 2 Australasian Leukaemia & Lymphoma Group NHL26 Study. 63rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta Ga, Dec 11-14, 2021. AMSTERDAM: ELSEVIER. doi: 10.1182/blood-2021-146343 |
2020 Conference Publication A cost-effectiveness analysis of front-line treatment strategies in early stage follicular lymphomaTobin, Joshua W.D., Hapgood, Greg, Gandhi, Maher K., Mollee, Peter, Ma, Ti, Crothers, Anna and Scuffham, Paul (2020). A cost-effectiveness analysis of front-line treatment strategies in early stage follicular lymphoma. 62nd ASH Annual Meeting and Exposition, Online, 5-8 December 2020. Washington, DC USA: American Society of Hematology. doi: 10.1182/blood-2020-138590 |
2020 Conference Publication Neoantigens are typically associated with intact HLA class I presentation in early-stage follicular lymphomaTsang, Hennes, Patch, Ann-Marie, Keane, Colm, Law, Soi C., Gunawardana, Jay, Blombery, Piers, Thompson, Ella R., Sabdia, Muhammed B., De Long, Lilia Merida, Belle, Clemence J., Nath, Karthik, Tobin, Joshua W.D., Kazakoff, Stephen H., Seymour, John F., MacManus, Michael and Gandhi, Maher K. (2020). Neoantigens are typically associated with intact HLA class I presentation in early-stage follicular lymphoma. 62nd ASH Annual Meeting and Exposition, Online, 5-8 December 2020. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2020-135954 |
2019 Conference Publication Intra-tumoral CD8+T-cells in follicular lymphoma contain large clonal expansions that are amenable to dual-checkpoint blockadeNath, Karthik, Law, Soi C., Sabdia, Muhammed B., De Long, Lilia Merida, Shanavas, Mohamed, Tobin, Joshua W. D., Gunawardana, Jay, Vari, Frank, Halliday, Sarah-Jane, Hernandez, Annette, Cross, Donna, Bird, Robert J., Keane, Colm and Gandhi, Maher K. (2019). Intra-tumoral CD8+T-cells in follicular lymphoma contain large clonal expansions that are amenable to dual-checkpoint blockade. 61st Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Orlando, FL, United States, 7 - 10 December 2019. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2019-130050 |
2019 Conference Publication EBV+ CNS lymphomas have a distinctive tumor microenvironment and genetic profile, which is amenable to combination 3rd party EBV-specific CTL and Ibrutinib therapyGandhi, M.K., Hoang, T., Tobin, J.W., Law, S.C., Talaulikar, D., Jain, S., Vari, F., Murigneux, V., Fink, L., Gunawardana, J., Gould, C., Oey, H., Delecluse, S., Trappe, R.U., Merida de Long, L., Sabdia, M.B., Bhagat, G., Hapgood, G., Blyth, E., Clancy, L., Casey, J., Wight, J., Hawkes, E. and Keane, C. (2019). EBV+ CNS lymphomas have a distinctive tumor microenvironment and genetic profile, which is amenable to combination 3rd party EBV-specific CTL and Ibrutinib therapy. 15th International Conference on Malignant Lymphoma, Lugano, Switzerland, 18–22 June 2019. Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/hon.91_2629 |
2019 Conference Publication B2M Gene Expression Reflects an Immunologically Active Tumor Microenvironment in DLBCLGould, Clare, Keane, Colm, Murigneux, Valentine, Oey, Harald, Ellis, Jonathan, Birch, Simone, Gunawardana, Jay, Talaulikar, Dipti, Hertzberg, Mark S., Jones, Kimberley and Gandhi, Maher K. (2019). B2M Gene Expression Reflects an Immunologically Active Tumor Microenvironment in DLBCL. ASH Annual Meeting, Orlando, FL, United States, 7-10 December 2019. Washington, DC, United States: American Society of Hematology. doi: 10.1182/blood-2019-126537 |
2018 Conference Publication A critical role for intratumoral and circulating LAG3 in classical Hodgkin Lymphoma: analysis from the Rathl prospective phase III international clinical trialAbro, Emad Uddin, Law, Soi C., Keane, Colm, Birch, Simone, Sabdia, Muhammed Bilal, Tobin, Joshua W. D., Johnson, Peter, Trotman, Judith, Berkahn, Leanne, Fulham, Michael, Anderson, Richard A., Saunderson, Anne L., Gunawardana, Jay, Cross, Donna, Hernandez, Annette, Halliday, Sarah-Jane, Bird, Robert, Law, W. P., Gill, Devinder and Gandhi, Maher K. (2018). A critical role for intratumoral and circulating LAG3 in classical Hodgkin Lymphoma: analysis from the Rathl prospective phase III international clinical trial. 60th ASH Annual Meeting, San Diego, CA United States, 1-4 December 2020. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood-2018-99-112008 |