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2021

Journal Article

Human CD141+ dendritic cells (cDC1) are impaired in patients with advanced melanoma but can be targeted to enhance anti-PD-1 in a humanized mouse model

Lee, Yoke Seng, O'Brien, Liam J., Walpole, Carina M., Pearson, Frances E., Leal-Rojas, Ingrid M., Masterman, Kelly-Anne, Atkinson, Victoria, Barbour, Andrew and Radford, Kristen J. (2021). Human CD141+ dendritic cells (cDC1) are impaired in patients with advanced melanoma but can be targeted to enhance anti-PD-1 in a humanized mouse model. Journal for ImmunoTherapy of Cancer, 9 (3) e001963, 1-12. doi: 10.1136/jitc-2020-001963

Human CD141+ dendritic cells (cDC1) are impaired in patients with advanced melanoma but can be targeted to enhance anti-PD-1 in a humanized mouse model

2021

Journal Article

Complications and survival after hybrid and fully minimally invasive oesophagectomy

Veenstra, M. M. K., Smithers, B. M., Visser, E., Edholm, D., Brosda, S., Thomas, J. M., Gotley, D. C., Thomson, I. G., Wijnhoven, B. P. L. and Barbour, A. P. (2021). Complications and survival after hybrid and fully minimally invasive oesophagectomy. BJS Open, 5 (1) zraa033, 1-7. doi: 10.1093/bjsopen/zraa033

Complications and survival after hybrid and fully minimally invasive oesophagectomy

2021

Journal Article

Targeting DNA damage response and replication stress in pancreatic cancer

Dreyer, Stephan B., Upstill-Goddard, Rosie, Paulus-Hock, Viola, Paris, Clara, Lampraki, Eirini-Maria, Dray, Eloise, Serrels, Bryan, Caligiuri, Giuseppina, Rebus, Selma, Plenker, Dennis, Galluzzo, Zachary, Brunton, Holly, Cunningham, Richard, Tesson, Mathias, Nourse, Craig, Bailey, Ulla-Maja, Jones, Marc D., Moran-Jones, Kim, Wright, Derek W., Duthie, Fraser, Oien, Karin, Evers, Lisa, McKay, Colin J., McGregor, Grant A., Gulati, Aditi, Brough, Rachel, Bajrami, Ilirjana, Pettitt, Stephan, Dziubinski, Michele L. ... Sansom, Owen J. (2021). Targeting DNA damage response and replication stress in pancreatic cancer. Gastroenterology, 160 (1), 362-377.e13. doi: 10.1053/j.gastro.2020.09.043

Targeting DNA damage response and replication stress in pancreatic cancer

2020

Journal Article

Clinical pathways and outcomes of patients with Barrett’s esophagus in tertiary care settings: a prospective longitudinal cohort study in Australia, 2008–2016

Na, Renhua, Miura, Kyoko, O’Brien, Suzanne, Eslick, Guy D., Kendall, Bradley J., Hourigan, Luke F., Bourke, Michael, Cox, Michael R., Farrokhzadi, Laal, Levert-Mignon, Angelique J., Barbour, Andrew P., Clemons, Nicholas J., Duong, Cuong P., Lord, Reginald V., Phillips, Wayne A., Watson, David I. and Whiteman, David C. (2020). Clinical pathways and outcomes of patients with Barrett’s esophagus in tertiary care settings: a prospective longitudinal cohort study in Australia, 2008–2016. Diseases of the Esophagus, 34 (8) doaa119. doi: 10.1093/dote/doaa119

Clinical pathways and outcomes of patients with Barrett’s esophagus in tertiary care settings: a prospective longitudinal cohort study in Australia, 2008–2016

2020

Journal Article

Sex differences in oncogenic mutational processes

Li, Constance H., Prokopec, Stephenie D., Sun, Ren X., Yousif, Fouad, Schmitz, Nathaniel, Al-Shahrour, Fatima, Atwal, Gurnit, Bailey, Peter J., Biankin, Andrew V., Boutros, Paul C., Campbell, Peter J., Chang, David K., Cooke, Susanna L., Deshpande, Vikram, Faltas, Bishoy M., Faquin, William C., Garraway, Levi, Getz, Gad, Grimmond, Sean M., Haider, Syed, Hoadley, Katherine A., Jiao, Wei, Kaiser, Vera B., Karlić, Rosa, Kato, Mamoru, Kübler, Kirsten, Lazar, Alexander J., Li, Constance H., Louis, David N. ... Lakhani, Sunil R. (2020). Sex differences in oncogenic mutational processes. Nature Communications, 11 (1) 4330. doi: 10.1038/s41467-020-17359-2

Sex differences in oncogenic mutational processes

2020

Journal Article

Divergent mutational processes distinguish hypoxic and normoxic tumours

Bhandari, Vinayak, Li, Constance H., Bristow, Robert G., Boutros, Paul C., Aaltonen, Lauri A., Abascal, Federico, Abeshouse, Adam, Aburatani, Hiroyuki, Adams, David J., Agrawal, Nishant, Ahn, Keun Soo, Ahn, Sung-Min, Aikata, Hiroshi, Akbani, Rehan, Akdemir, Kadir C., Al-Ahmadie, Hikmat, Al-Sedairy, Sultan T., Al-Shahrour, Fatima, Alawi, Malik, Albert, Monique, Aldape, Kenneth, Alexandrov, Ludmil B., Ally, Adrian, Alsop, Kathryn, Alvarez, Eva G., Amary, Fernanda, Amin, Samirkumar B., Aminou, Brice, Ammerpohl, Ole ... PCAWG Consortium (2020). Divergent mutational processes distinguish hypoxic and normoxic tumours. Nature Communications, 11 (1) 737. doi: 10.1038/s41467-019-14052-x

Divergent mutational processes distinguish hypoxic and normoxic tumours

2020

Journal Article

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

Bailey, Matthew H., Meyerson, William U., Dursi, Lewis Jonathan, Wang, Liang-Bo, Dong, Guanlan, Liang, Wen-Wei, Weerasinghe, Amila, Li, Shantao, Kelso, Sean, Akbani, Rehan, Anur, Pavana, Bailey, Matthew H., Buchanan, Alex, Chiotti, Kami, Covington, Kyle, Creason, Allison, Ding, Li, Ellrott, Kyle, Fan, Yu, Foltz, Steven, Getz, Gad, Hale, Walker, Haussler, David, Hess, Julian M., Hutter, Carolyn M., Kandoth, Cyriac, Kasaian, Katayoon, Kasapi, Melpomeni, Larson, Dave ... von Mering, Christian (2020). Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples. Nature Communications, 11 (1) 4748. doi: 10.1038/s41467-020-18151-y

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

2020

Journal Article

Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (Nature Communications, (2020), 11, 1, (4748), 10.1038/s41467-020-18151-y)

Bailey, Matthew H., Meyerson, William U., Dursi, Lewis Jonathan, Wang, Liang-Bo, Dong, Guanlan, Liang, Wen-Wei, Weerasinghe, Amila, Li, Shantao, Li, Yize, Kelso, Sean, Akbani, Rehan, Anur, Pavana, Bailey, Matthew H., Buchanan, Alex, Chiotti, Kami, Covington, Kyle, Creason, Allison, Ding, Li, Ellrott, Kyle, Fan, Yu, Foltz, Steven, Getz, Gad, Hale, Walker, Haussler, David, Hess, Julian M., Hutter, Carolyn M., Kandoth, Cyriac, Kasaian, Katayoon, Kasapi, Melpomeni ... von Mering, Christian (2020). Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (Nature Communications, (2020), 11, 1, (4748), 10.1038/s41467-020-18151-y). Nature Communications, 11 (1) 6232. doi: 10.1038/s41467-020-20128-w

Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (Nature Communications, (2020), 11, 1, (4748), 10.1038/s41467-020-18151-y)

2020

Journal Article

Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig

Rubanova, Yulia, Shi, Ruian, Harrigan, Caitlin F., Li, Roujia, Wintersinger, Jeff, Sahin, Nil, Deshwar, Amit G., Dentro, Stefan C., Leshchiner, Ignaty, Gerstung, Moritz, Jolly, Clemency, Haase, Kerstin, Tarabichi, Maxime, Wintersinger, Jeff, Deshwar, Amit G., Yu, Kaixian, Gonzalez, Santiago, Rubanova, Yulia, Macintyre, Geoff, Adams, David J., Anur, Pavana, Beroukhim, Rameen, Boutros, Paul C., Bowtell, David D., Campbell, Peter J., Cao, Shaolong, Christie, Elizabeth L., Cmero, Marek, Cun, Yupeng ... PCAWG Consortium (2020). Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig. Nature Communications, 11 (1) 731, 1-12. doi: 10.1038/s41467-020-14352-7

Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig

2020

Journal Article

A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns

Jiao, Wei, Atwal, Gurnit, Polak, Paz, Karlic, Rosa, Cuppen, Edwin, Al-Shahrour, Fatima, Atwal, Gurnit, Bailey, Peter J., Biankin, Andrew V., Boutros, Paul C., Campbell, Peter J., Chang, David K., Cooke, Susanna L., Deshpande, Vikram, Faltas, Bishoy M., Faquin, William C., Garraway, Levi, Getz, Gad, Grimmond, Sean M., Haider, Syed, Hoadley, Katherine A., Jiao, Wei, Kaiser, Vera B., Karlic, Rosa, Kato, Mamoru, Kübler, Kirsten, Lazar, Alexander J., Li, Constance H., Louis, David N. ... PCAWG Consortium (2020). A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns. Nature Communications, 11 (1) 728. doi: 10.1038/s41467-019-13825-8

A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns

2020

Journal Article

Pathogenic germline variants are associated with poor survival in stage III/IV melanoma patients

Aoude, Lauren G., Bonazzi, Vanessa F., Brosda, Sandra, Patel, Kalpana, Koufariotis, Lambros T., Oey, Harald, Nones, Katia, Wood, Scott, Pearson, John V., Lonie, James M., Arneil, Melissa, Atkinson, Victoria, Smithers, B. Mark, Waddell, Nicola and Barbour, Andrew P. (2020). Pathogenic germline variants are associated with poor survival in stage III/IV melanoma patients. Scientific Reports, 10 (1) 17687, 17687. doi: 10.1038/s41598-020-74956-3

Pathogenic germline variants are associated with poor survival in stage III/IV melanoma patients

2020

Journal Article

Factors predicting toxicity and response following isolated limb infusion for melanoma: an international multi-centre study

Kenyon-Smith, Timothy J., Kroon, Hidde M., Miura, John T., Teras, Jüri, Beasley, Georgia M., Mullen, Dean, Farrow, Norma E., Mosca, Paul J., Lowe, Michael C., Farley, Clara R., Potdar, Aishwarya, Daou, Hala, Sun, James, Farma, Jeffrey M., Henderson, Michael A., Speakman, David, Serpell, Jonathan, Delman, Keith A., Smithers, B. Mark, Barbour, Andrew, Coventry, Brendon J., Tyler, Douglas S., Zager, Jonathan S. and Thompson, John F. (2020). Factors predicting toxicity and response following isolated limb infusion for melanoma: an international multi-centre study. European Journal of Surgical Oncology, 46 (11), 2140-2146. doi: 10.1016/j.ejso.2020.06.040

Factors predicting toxicity and response following isolated limb infusion for melanoma: an international multi-centre study

2020

Journal Article

HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer

Brunton, Holly, Caligiuri, Giuseppina, Cunningham, Richard, Upstill-Goddard, Rosie, Bailey, Ulla-Maja, Garner, Ian M., Nourse, Craig, Dreyer, Stephan, Jones, Marc, Moran-Jones, Kim, Wright, Derek W., Paulus-Hock, Viola, Nixon, Colin, Thomson, Gemma, Jamieson, Nigel B., McGregor, Grant A., Evers, Lisa, McKay, Colin J., Gulati, Aditi, Brough, Rachel, Bajrami, Ilirjana, Pettitt, Stephen J., Dziubinski, Michele L., Barry, Simon T., Grützmann, Robert, Brown, Robert, Curry, Edward, Allison, Sarah, Biankin, Andrew V. ... Australian Pancreatic Cancer Genome Initiative (2020). HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer. Cell Reports, 31 (6) 107625, 1-28. doi: 10.1016/j.celrep.2020.107625

HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer

2020

Journal Article

Australasian Gastrointestinal Trials Group (AGITG) and Trans-Tasman Radiation Oncology Group (TROG) guidelines for pancreatic stereotactic body radiation therapy (SBRT)

Oar, Andrew, Lee, Mark, Le, Hien, Hruby, George, Dalfsen, Raymond, Pryor, David, Lee, Dominique, Chu, Julie, Holloway, Lois, Briggs, Adam, Barbour, Andrew, Chander, Sarat, Ng, Sweet Ping, Samra, Jas, Shakeshaft, John, Goldstein, David, Nguyen, Nam, Goodman, Karyn A., Chang, Daniel T. and Kneebone, Andrew (2020). Australasian Gastrointestinal Trials Group (AGITG) and Trans-Tasman Radiation Oncology Group (TROG) guidelines for pancreatic stereotactic body radiation therapy (SBRT). Practical Radiation Oncology, 10 (3), e136-e146. doi: 10.1016/j.prro.2019.07.018

Australasian Gastrointestinal Trials Group (AGITG) and Trans-Tasman Radiation Oncology Group (TROG) guidelines for pancreatic stereotactic body radiation therapy (SBRT)

2020

Journal Article

Management of early-stage gastro-esophageal cancers: expert perspectives from the Australasian Gastrointestinal Trials Group (AGITG) with invited international faculty

Roy, Amitesh C., Shapiro, Jeremy, Burge, Matt, Karapetis, Christos S., Pavlakis, Nick, Segelov, Eva, Chau, Ian, Lordick, Florian, Chen, Li-Tong, Barbour, Andrew, Tebbutt, Niall and Price, Tim (2020). Management of early-stage gastro-esophageal cancers: expert perspectives from the Australasian Gastrointestinal Trials Group (AGITG) with invited international faculty. Expert Review of Anticancer Therapy, 20 (4), 305-324. doi: 10.1080/14737140.2020.1746185

Management of early-stage gastro-esophageal cancers: expert perspectives from the Australasian Gastrointestinal Trials Group (AGITG) with invited international faculty

2020

Journal Article

International multicenter experience of isolated limb infusion for in-transit melanoma metastases in octogenarian and nonagenarian patients

Teras, Jüri, Kroon, Hidde M., Miura, John T., Kenyon-Smith, Tim, Beasley, Georgia M., Mullen, Dean, Farrow, Norma E., Mosca, Paul J., Lowe, Michael C., Farley, Clara R., Potdar, Aishwarya, Daou, Hala, Sun, James, Carr, Michael, Farma, Jeffrey M., Henderson, Michael A., Speakman, David, Serpell, Jonathan, Delman, Keith A., Smithers, B. Mark, Barbour, Andrew, Tyler, Douglas S., Coventry, Brendon J., Zager, Jonathan S. and Thompson, John F. (2020). International multicenter experience of isolated limb infusion for in-transit melanoma metastases in octogenarian and nonagenarian patients. Annals of Surgical Oncology, 27 (5), 1420-1429. doi: 10.1245/s10434-020-08312-0

International multicenter experience of isolated limb infusion for in-transit melanoma metastases in octogenarian and nonagenarian patients

2020

Journal Article

Pan-cancer analysis of whole genomes

Campbell, Peter J., Getz, Gad, Korbel, Jan O., Stuart, Joshua M., Jennings, Jennifer L., Stein, Lincoln D., Perry, Marc D., Nahal-Bose, Hardeep K., Ouellette, B. F. Francis, Li, Constance H., Rheinbay, Esther, Nielsen, G. Petur, Sgroi, Dennis C., Wu, Chin-Lee, Faquin, William C., Deshpande, Vikram, Boutros, Paul C., Lazar, Alexander J., Hoadley, Katherine A., Louis, David N., Dursi, L. Jonathan, Yung, Christina K., Bailey, Matthew H., Saksena, Gordon, Raine, Keiran M., Buchhalter, Ivo, Kleinheinz, Kortine, Schlesner, Matthias, Zhang, Junjun ... Hamdy, Freddie C. (2020). Pan-cancer analysis of whole genomes. Nature, 578 (7793), 82-93. doi: 10.1038/s41586-020-1969-6

Pan-cancer analysis of whole genomes

2020

Journal Article

Genomic basis for RNA alterations in cancer

Calabrese, Claudia, Davidson, Natalie R., Demircioğlu, Deniz, Fonseca, Nuno A., He, Yao, Kahles, André, Lehmann, Kjong-Van, Liu, Fenglin, Shiraishi, Yuichi, Soulette, Cameron M., Urban, Lara, Greger, Liliana, Li, Siliang, Liu, Dongbing, Perry, Marc D., Xiang, Qian, Zhang, Fan, Zhang, Junjun, Bailey, Peter, Erkek, Serap, Hoadley, Katherine A., Hou, Yong, Huska, Matthew R., Kilpinen, Helena, Korbel, Jan O., Marin, Maximillian G., Markowski, Julia, Nandi, Tannistha, Pan-Hammarström, Qiang ... von Mering, Christian (2020). Genomic basis for RNA alterations in cancer. Nature, 578 (7793), 129-136. doi: 10.1038/s41586-020-1970-0

Genomic basis for RNA alterations in cancer

2020

Journal Article

Comprehensive molecular characterization of mitochondrial genomes in human cancers

Yuan, Yuan, Ju, Young Seok, Kim, Youngwook, Li, Jun, Wang, Yumeng, Yoon, Christopher J., Yang, Yang, Martincorena, Inigo, Creighton, Chad J., Weinstein, John N., Xu, Yanxun, Han, Leng, Kim, Hyung-Lae, Nakagawa, Hidewaki, Park, Keunchil, Campbell, Peter J., Liang, Han, Aaltonen, Lauri A., Abascal, Federico, Abeshouse, Adam, Aburatani, Hiroyuki, Adams, David J., Agrawal, Nishant, Ahn, Keun Soo, Ahn, Sung-Min, Aikata, Hiroshi, Akbani, Rehan, Akdemir, Kadir C., Al-Ahmadie, Hikmat ... von Mering, Christian (2020). Comprehensive molecular characterization of mitochondrial genomes in human cancers. Nature Genetics, 52 (3), 342-352. doi: 10.1038/s41588-019-0557-x

Comprehensive molecular characterization of mitochondrial genomes in human cancers

2020

Journal Article

Preoperative cisplatin, fluorouracil, and docetaxel with or without radiotherapy after poor early response to cisplatin and fluorouracil for resectable oesophageal adenocarcinoma (AGITG DOCTOR): results from a multicentre, randomised controlled phase II trial

Barbour, A P, Walpole, E T, Mai, G T, Barnes, E H, Watson, D I, Ackland, S P, Martin, J M, Burge, M, Finch, R, Karapetis, C S, Shannon, J, Nott, L M, Varma, S, Marx, G, Falk, G L, Gebski, V, Oostendorp, M, Wilson, K, Thomas, J, Lampe, G, Zalcberg, J R, Simes, J, Smithers, B M and DOCTOR investigators (2020). Preoperative cisplatin, fluorouracil, and docetaxel with or without radiotherapy after poor early response to cisplatin and fluorouracil for resectable oesophageal adenocarcinoma (AGITG DOCTOR): results from a multicentre, randomised controlled phase II trial. Annals of Oncology, 31 (2), 236-245. doi: 10.1016/j.annonc.2019.10.019

Preoperative cisplatin, fluorouracil, and docetaxel with or without radiotherapy after poor early response to cisplatin and fluorouracil for resectable oesophageal adenocarcinoma (AGITG DOCTOR): results from a multicentre, randomised controlled phase II trial