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2021

Journal Article

An international survey on aminoglycoside practices in critically ill patients: the AMINO III study

Roger, Claire, Louart, Benjamin, Elotmani, Loubna, Barton, Greg, Escobar, Leslie, Koulenti, Despoina, Lipman, Jeffrey, Leone, Marc, Muller, Laurent, Boutin, Caroline, Amour, Julien, Banakh, Iouri, Cousson, Joel, Bourenne, Jeremy, Constantin, Jean-Michel, Albanese, Jacques, Roberts, Jason A., Lefrant, Jean-Yves, Darchy, Bruno, Sigismond, Lasocki, Debbat, Karim, Moschietto, Sébastien, Capellier, Gilles, Biais, Matthieu, Brunin, Guillaume, Huet, Olivier, Hausermann, Marie-Hélène, Just, Bernard, Constantin, Jean-Michel ... Felton, Timothy (2021). An international survey on aminoglycoside practices in critically ill patients: the AMINO III study. Annals of Intensive Care, 11 (1) 49, 49. doi: 10.1186/s13613-021-00834-4

An international survey on aminoglycoside practices in critically ill patients: the AMINO III study

2021

Journal Article

Initial antimicrobial management of sepsis

Niederman, Michael S., Baron, Rebecca M., Bouadma, Lila, Calandra, Thierry, Daneman, Nick, DeWaele, Jan, Kollef, Marin H., Lipman, Jeffrey and Nair, Girish B. (2021). Initial antimicrobial management of sepsis. Critical Care, 25 (1) 307, 307. doi: 10.1186/s13054-021-03736-w

Initial antimicrobial management of sepsis

2021

Journal Article

Micafungin population PK analysis in healthy and septic pigs: can the septic porcine model predict the micafungin PK in septic patients?

Garbez, Nicolas, Mbatchi, Litaty C., Louart, Guillaume, Wallis, Steven C., Muller, Laurent, Lipman, Jeffrey, Roberts, Jason A., Lefrant, Jean-Yves and Roger, Claire (2021). Micafungin population PK analysis in healthy and septic pigs: can the septic porcine model predict the micafungin PK in septic patients?. Pharmaceutical Research, 38 (11), 1863-1871. doi: 10.1007/s11095-021-03137-2

Micafungin population PK analysis in healthy and septic pigs: can the septic porcine model predict the micafungin PK in septic patients?

2021

Journal Article

Ventriculitis: infection or inflammation

Ramanan, Mahesh, Shorr, Andrew and Lipman, Jeffrey (2021). Ventriculitis: infection or inflammation. Antibiotics, 10 (10) 1246, 1246. doi: 10.3390/antibiotics10101246

Ventriculitis: infection or inflammation

2021

Journal Article

Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis

Billot, Laurent, Lipman, Jeffrey, Brett, Stephen J., Waele, Jan J. De, Cotta, Menino Osbert, Davis, Joshua S., Finfer, Simon, Hammond, Naomi E., Knowles, Serena, McGuinness, Shay, Myburgh, John, Paterson, David L., Peake, Sandra, Rajbhandari, Dorrilyn, Rhodes, Andrew, Roger, Claire, Roberts, Jason A., Shirwadkar, Charudatt, Starr, Therese, Taylor, Colman, Dulhunty, Joel M. and For the BLING III Investigators (2021). Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis. Critical Care and Resuscitation, 23 (3), 273-284. doi: 10.51893/2021.3.oa4

Statistical analysis plan for the BLING III study: a phase 3 multicentre randomised controlled trial of continuous versus intermittent β-lactam antibiotic infusion in critically ill patients with sepsis

2021

Journal Article

Pharmacokinetics of fluconazole and ganciclovir as combination antimicrobial chemotherapy on ECMO- A case report

Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2021). Pharmacokinetics of fluconazole and ganciclovir as combination antimicrobial chemotherapy on ECMO- A case report. International Journal of Antimicrobial Agents, 58 (5) 106431, 106431. doi: 10.1016/j.ijantimicag.2021.106431

Pharmacokinetics of fluconazole and ganciclovir as combination antimicrobial chemotherapy on ECMO- A case report

2021

Journal Article

Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections caused by AmpC beta-lactamase producing Enterobacter spp., Citrobacter freundii, Morganella morganii, Providencia spp., or Serratia marcescens: a pilot multi-center randomized controlled trial (MERINO-2)

Stewart, Adam G., Paterson, David L., Young, Barnaby, Lye, David C, Davis, Joshua S., Schneider, Kellie, Yilmaz, Mesut, Dinleyici, Rumeysa, Runnegar, Naomi, Henderson, Andrew, Archuleta, Sophia, Kalimuddin, Shirin, Forde, Brian M., Chatfield, Mark D., Bauer, Michelle J., Lipman, Jeffrey, Harris-Brown, Tiffany, Harris, Patrick N. A. and for the MERINO Trial Investigators and the Australasian Society for Infectious Disease Clinical Research Network (ASID-CRN) (2021). Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections caused by AmpC beta-lactamase producing Enterobacter spp., Citrobacter freundii, Morganella morganii, Providencia spp., or Serratia marcescens: a pilot multi-center randomized controlled trial (MERINO-2). Open Forum Infectious Diseases, 8 (8) ofab387, ofab387. doi: 10.1093/ofid/ofab387

Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections caused by AmpC beta-lactamase producing Enterobacter spp., Citrobacter freundii, Morganella morganii, Providencia spp., or Serratia marcescens: a pilot multi-center randomized controlled trial (MERINO-2)

2021

Journal Article

Prediction accuracy of commonly used pneumonia severity scores in Aboriginal patients with severe community‐acquired pneumonia – a retrospective study

Tsai, Danny, Secombe, Paul, Chiong, Fabian, Ullah, Shahid, Lipman, Jeffrey and Hewagama, Saliya (2021). Prediction accuracy of commonly used pneumonia severity scores in Aboriginal patients with severe community‐acquired pneumonia – a retrospective study. Internal Medicine Journal, 53 (1), 51-60. doi: 10.1111/imj.15534

Prediction accuracy of commonly used pneumonia severity scores in Aboriginal patients with severe community‐acquired pneumonia – a retrospective study

2021

Journal Article

Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT)

Irwin, Adam D., Coin, Lachlan J. M., Harris, Patrick N. A., Cotta, Menino Osbert, Bauer, Michelle J., Buckley, Cameron, Balch, Ross, Kruger, Peter, Meyer, Jason, Shekar, Kiran, Brady, Kara, Fourie, Cheryl, Sharp, Natalie, Vlad, Luminita, Whiley, David, Beatson, Scott A., Forde, Brian M., Paterson, David, Clark, Julia, Hajkowicz, Krispin, Raman, Sainath, Bialasiewicz, Seweryn, Lipman, Jeffrey, Schlapbach, Luregn J. and Roberts, Jason A. (2021). Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT). Frontiers in Cellular and Infection Microbiology, 11 667680, 1-8. doi: 10.3389/fcimb.2021.667680

Optimising treatment outcomes for children and adults through rapid genome sequencing of sepsis pathogens. A study protocol for a prospective, multi-centre trial (DIRECT)

2021

Journal Article

Micafungin population PK analysis in plasma and peritoneal fluid in septic patients with intra-abdominal infections: a prospective cohort study

Garbez, Nicolas, Mbatchi, Litaty, Wallis, Steven C., Muller, Laurent, Lipman, Jeffrey, Roberts, Jason A., Lefrant, Jean-Yves and Roger, Claire (2021). Micafungin population PK analysis in plasma and peritoneal fluid in septic patients with intra-abdominal infections: a prospective cohort study. Antimicrobial Agents and Chemotherapy, 65 (7) e02307-20, 1-13. doi: 10.1128/aac.02307-20

Micafungin population PK analysis in plasma and peritoneal fluid in septic patients with intra-abdominal infections: a prospective cohort study

2021

Journal Article

Development and validation of a UHPLC-MS/MS method to measure cefotaxime and metabolite desacetylcefotaxime in blood plasma: a pilot study suitable for capillary microsampling in critically ill children

Guerra Valero, Yarmarly C., Dorofaeff, Tavey, Roberts, Jason A., Lipman, Jeffrey, Coulthard, Mark G., Sparkes, Louise, Wallis, Steven C. and Parker, Suzanne L. (2021). Development and validation of a UHPLC-MS/MS method to measure cefotaxime and metabolite desacetylcefotaxime in blood plasma: a pilot study suitable for capillary microsampling in critically ill children. Analytical and Bioanalytical Chemistry, 413 (17), 4483-4491. doi: 10.1007/s00216-021-03411-7

Development and validation of a UHPLC-MS/MS method to measure cefotaxime and metabolite desacetylcefotaxime in blood plasma: a pilot study suitable for capillary microsampling in critically ill children

2021

Journal Article

Antimicrobial lessons from a large observational cohort on intra-abdominal infections in intensive care units

Vogelaers, Dirk, Blot, Stijn, Van den Berge, Andries, Montravers, Philippe, Francois, Guy, Labeau, Sonia, Blot, Koen, Deschepper, Mieke, Antonelli, Massimo, Lipman, Jeffrey, Lamrous, Amin, Pereyra, Cecilia, Lipovestky, Fernando, Koulenti, Despoina, De Waele, Jan, Rezende-Neto, Joao, Cardenas, Yenny, Vymazal, Tomas, Fjeldsoee-Nielsen, Hans, Kott, Matthias, Kostoula, Arvaniti, Javeri, Yash, Girardis, Massimo, Einav, Sharon, de Lange, Dylan, Makikado, Luis Daniel Umezawa, Mikstacki, Adam, Paiva, José-Artur, Tomescu, Dana ... Davis, Noelle (2021). Antimicrobial lessons from a large observational cohort on intra-abdominal infections in intensive care units. Drugs, 81 (9), 1065-1078. doi: 10.1007/s40265-021-01534-w

Antimicrobial lessons from a large observational cohort on intra-abdominal infections in intensive care units

2021

Journal Article

Microsampling to support pharmacokinetic clinical studies in pediatrics

Guerra Valero, Yarmarly, Dorofaeff, Tavey, Parker, Lisa, Coulthard, Mark G., Sparkes, Louise, Lipman, Jeffrey, Wallis, Steven C., Roberts, Jason A. and Parker, Suzanne L. (2021). Microsampling to support pharmacokinetic clinical studies in pediatrics. Pediatric Research, 91 (6), 1-5. doi: 10.1038/s41390-021-01586-4

Microsampling to support pharmacokinetic clinical studies in pediatrics

2021

Journal Article

A Multicenter Observational Study Evaluating Outcomes Associated With Antibiotic Combination Versus Monotherapy in Patients With Septic Shock

Torisson, Gustav, Bruun Madsen, Martin, Schmidt Davidsen, Agnes, Perner, Anders, Lipman, Jeffrey, Dulhunty, Joel and Sjövall, Fredrik (2021). A Multicenter Observational Study Evaluating Outcomes Associated With Antibiotic Combination Versus Monotherapy in Patients With Septic Shock. Critical Care Explorations, 3 (5) e0383, 1-10. doi: 10.1097/CCE.0000000000000383

A Multicenter Observational Study Evaluating Outcomes Associated With Antibiotic Combination Versus Monotherapy in Patients With Septic Shock

2021

Journal Article

Influence of the Obesity Phenotype on the Adequacy of Antibiotic Prophylaxis with Cefoxitin for Obese Patients Undergoing Bariatric Surgery: Lessons Learnt and Future Considerations

Belveyre, Thibaut, Scala-Bertola, Julien, Esposito, Mathieu, Luc, Amandine, Lipman, Jeffrey and Novy, Emmanuel (2021). Influence of the Obesity Phenotype on the Adequacy of Antibiotic Prophylaxis with Cefoxitin for Obese Patients Undergoing Bariatric Surgery: Lessons Learnt and Future Considerations. European Journal of Drug Metabolism and Pharmacokinetics, 46 (4), 479-485. doi: 10.1007/s13318-021-00688-y

Influence of the Obesity Phenotype on the Adequacy of Antibiotic Prophylaxis with Cefoxitin for Obese Patients Undergoing Bariatric Surgery: Lessons Learnt and Future Considerations

2021

Journal Article

Early sequential microcirculation assessment in shocked patients as a predictor of outcome: a prospective observational cohort study

Holley, Anthony D., Dulhunty, Joel, Udy, Andrew, Midwinter, Mark, Lukin, Bill, Stuart, Janine, Boots, Robert, Lassig-Smith, Melissa, Holley, Robert B., Paratz, Jenny and Lipman, Jeffrey (2021). Early sequential microcirculation assessment in shocked patients as a predictor of outcome: a prospective observational cohort study. Shock, 55 (5), 581-586. doi: 10.1097/SHK.0000000000001578

Early sequential microcirculation assessment in shocked patients as a predictor of outcome: a prospective observational cohort study

2021

Journal Article

Lorazepam challenge test for catatonia

Smith, Samuel , Ketheesan, Sarangan , Touma, Emeile , Lipman, Jeffrey and Brown, Anthony F. T. (2021). Lorazepam challenge test for catatonia. Emergency Medicine Australasia, 33 (4) 1742-6723.13780, 763-764. doi: 10.1111/1742-6723.13780

Lorazepam challenge test for catatonia

2021

Journal Article

Impact of the epithelial lining fluid milieu on amikacin pharmacodynamics against Pseudomonas aeruginosa

Heffernan, Aaron J., Sime, Fekade B., Lim, Sazlyna Mohd Sazlly, Naicker, Saiyuri, Andrews, Katherine T., Ellwood, David, Lipman, Jeffrey, Grimwood, Keith and Roberts, Jason A. (2021). Impact of the epithelial lining fluid milieu on amikacin pharmacodynamics against Pseudomonas aeruginosa. Drugs in R&D, 21 (2), 203-215. doi: 10.1007/s40268-021-00344-5

Impact of the epithelial lining fluid milieu on amikacin pharmacodynamics against Pseudomonas aeruginosa

2021

Journal Article

A narrative review on antimicrobial therapy in septic shock: updates and controversies

Ling, Lowell, Joynt, Gavin Matthew and Lipman, Jeffrey (2021). A narrative review on antimicrobial therapy in septic shock: updates and controversies. Current Opinion in Anaesthesiology, 34 (2), 92-98. doi: 10.1097/ACO.0000000000000954

A narrative review on antimicrobial therapy in septic shock: updates and controversies

2021

Journal Article

Evaluation of meropenem-ciprofloxacin combination dosage regimens for the pharmacokinetics of critically ill patients with augmented renal clearance

Agyeman, Akosua A., Rogers, Kate E., Tait, Jessica R., Bergen, Phillip J., Kirkpatrick, Carl M., Wallis, Steven C., Bulitta, Jürgen B., Paterson, David L., Lipman, Jeffrey, Nation, Roger L., Roberts, Jason A. and Landersdorfer, Cornelia B. (2021). Evaluation of meropenem-ciprofloxacin combination dosage regimens for the pharmacokinetics of critically ill patients with augmented renal clearance. Clinical Pharmacology and Therapeutics, 109 (4), 1104-1115. doi: 10.1002/cpt.2191

Evaluation of meropenem-ciprofloxacin combination dosage regimens for the pharmacokinetics of critically ill patients with augmented renal clearance